Projects 1975 2024

Filter
Finished
Research project
Epidermal Growth Factor Receptor
Ligands
Ubiquitination
Phosphorylation
Endosomes

Development of a Novel Class for Opioid Drugs

Dokholyan, N. & Diatchenko, L.

National Institutes of Health

4/1/129/30/14

Project: Research project

Opioid Analgesics
mu Opioid Receptor
Protein Isoforms
Analgesics
Pharmaceutical Preparations
Melanoma
Therapeutics
Carcinogenesis
Quality of Life
Isothiocyanates
Melanoma
Small Interfering RNA
Phosphotransferases
Therapeutics
Neoplasms

ISC-4 as a Novel Lung Cancer Chemopreventive Agent

Sharma, A. & Sharma, A. K.

National Institutes of Health

9/30/098/31/11

Project: Research project

Lung Neoplasms
Selenium
Neoplasms
Enzymes
Isothiocyanates
Substance-Related Disorders
Recurrence
kappa Opioid Receptor
Narcotic Antagonists
Opioid Receptors
Selenium
Selenious Acid
Prostatic Neoplasms
Caspases
Apoptosis
Melanoma
Apoptosis
plumbagin
Sunscreening Agents
Skin Neoplasms
Thioridazine
Stereotyped Behavior
Cricetinae
Stereotypic Movement Disorder
Pharmaceutical Preparations
Adenosine Triphosphatases
Ouabain
Messenger RNA
Protein Isoforms
Cardiac Glycosides
Olfactory Bulb
Smell
Aptitude
Central Nervous System
Synaptic Vesicles
Self Administration
Genomics
Cocaine
Cocaine-Related Disorders
Gene Expression

IMMUNE AND BRAIN STUDIES

Mailman, R. & Allen, A.

National Institutes of Health

12/8/8912/27/94

Project: Research project

Brain
Parturition
Haplorhini
Rodentia
Lithium

Functional Selectivity: A Novel approach for CNS Drug Discovery

Mailman, R., Roth, B., Caron, M. G., Caron, M. G., Wetsel, W. & Jian, J.

National Institutes of Health

9/28/074/30/18

Project: Research project

Ligands
Dopamine D2 Receptors
Antipsychotic Agents
Schizophrenia
Signal Transduction
Epitopes
Photoreceptor Cells
Isoenzymes
Hydra
Genes

NEUROBIOLOGY OF ENVIRONMENTAL POLLUTANTS

Mailman, R., Krigman, M., Goodrum, J., Morell, P., Suzuki, K., Bouldin, T. & Krigman, M.

National Institutes of Health

5/1/759/19/98

Project: Research project

Environmental Pollutants
Neurobiology
Nervous System
Metals
Organotin Compounds
Superoxide Dismutase
Cell Movement
Reactive Oxygen Species
Neoplasms
Focal Adhesion Protein-Tyrosine Kinases
oxaliplatin
Platinum
Cisplatin
DNA-Directed DNA Polymerase
Nuclear magnetic resonance
Chemoprevention
Melanoma
Selenium Compounds
Isothiocyanates
Skin Neoplasms
Breast Neoplasms
Therapeutics
Biological Products
Heterografts
Cell Line

Prevention of PTEN deletion driven prostate cancer by selenium

Lu, J., Lu, J., Deng, Y. & Deng, Y.

National Institutes of Health

12/15/1011/30/13

Project: Research project

Selenium
Prostatic Neoplasms
Selenomethionine
Prostate
Vitamin E
Glioma
Glioblastoma
Biological Products
Brain Neoplasms
Stilbenes
Farnesyltranstransferase
Prostatic Neoplasms
zoledronic acid
Bone and Bones
Heterografts
Linoleic Acid
Mitogen-Activated Protein Kinases
Fats
Breast Neoplasms
Carcinogenesis
Ants
Bone Diseases
Prostatic Neoplasms
Breast Neoplasms
Morbidity
Neuropharmacology
Phenothiazines
Pharmaceutical Preparations
Thioridazine
Trifluoperazine
Celecoxib
Cyclooxygenase 2 Inhibitors
Chemoprevention
Colonic Neoplasms
Inbred F344 Rats
Protein Kinase C
Cysteine
Breast Neoplasms
Protein Isoforms
Phosphotransferases
Self Administration
Primates
Alcoholism
Biomarkers
Alcohols
Tyrosine 3-Monooxygenase
Biogenic Amines
Enzymes
Tryptophan Hydroxylase
biogenic amines

SYNTHESIS OF SELECTED CHEMICAL CARCINOGENS

Amin, S., Ruehle, P. & Kaplan, J.

National Institutes of Health

3/16/923/15/97

Project: Research project

Carcinogens
Derivatives
Polycyclic Aromatic Hydrocarbons
Polycyclic aromatic hydrocarbons
Metabolites

MULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISM

Vrana, K., Samson, H., Grant, K., McCool, B. & Friedman, D.

National Institutes of Health

7/1/946/30/19

Project: Research project

Alcoholism
Alcohols
Neurosciences
Biochemistry
Students

CHILD DEVELOPMENT AND MENTAL RETARDATION

Mailman, R., Hershey, H. G., Fordham, C., Helms, R. W., Suzuki, K., Burchinal, M., Piven, J., Reznick, J., Hatton, D., Boccia, M., Bailey, D., Skinner, D., Warren, S., Seltzer, M. M. & Belger, A.

National Institutes of Health

9/1/779/23/13

Project: Research project

Computer hardware
Information technology
Intranets
Computer programming
Application programs
Carcinogens
Derivatives
Polycyclic Aromatic Hydrocarbons
Metabolites
Purification
Dopamine Receptors
GTP-Binding Proteins
Adenylyl Cyclases
Dopamine
Lactotrophs
Carcinogenesis
Pentanones
Cytochrome P-450 Enzyme System
Lung
Microsomes
Genes
Adenosine Triphosphatases
Protein Isoforms
Complementary DNA
Ouabain

Targeted Sphingolipid Metabolism for Treatment of AML

Claxton, D., Wang, H., Wang, H., Amin, S., Liao, J. (., Fox, T., Loughran, T. P., Loughran, T. P., Kester, M., Kester, M. & Cabot, M. C.

National Institutes of Health

9/10/138/31/19

Project: Research project

Acute Myeloid Leukemia
Acid Ceramidase
Sphingolipids
Ceramides
Tamoxifen
Oxidation-Reduction
Reactive Oxygen Species
Neoplasm Metastasis
Neoplasms
Urinary Bladder Neoplasms
Amyotrophic Lateral Sclerosis
Mutation
Proteins
Neurodegenerative Diseases
Poisons
Epitopes
Carbohydrates
HIV
Viruses
Glycosylation
Chemoprevention
Melanoma
Small Interfering RNA
Skin
Technology
Chemoprevention
Small Interfering RNA
Melanoma
Phosphotransferases
Lymphatic System

A novel compound for colorectal cancer prevention

Sharma, A. & Sharma, A. K.

National Institutes of Health

7/11/143/31/17

Project: Research project

Aspirin
Colorectal Neoplasms
Hydrogen Cyanide
Inbred F344 Rats
Carcinogenesis
Infection
Anti-Bacterial Agents
Therapeutics
Bacteria
bolaamphiphile
Rubiaceae
Chemoprevention
Prostatic Neoplasms
Glucose
Apoptosis
Herbal Medicine
Chemoprevention
Prostate
Prostatic Neoplasms
Neoplasm Metastasis
Chemoprevention
Selenium
Prostatic Neoplasms
Selenomethionine
Prostate
Brain
Pharmaceutical Preparations
Functional groups
Bearings (structural)
Poisons