Organization profile

Organization profile

The Division of Colon and Rectal Surgery in the Department of Surgery at Penn State College of Medicine provides advanced and effective medical care, including state-of-the-art diagnostic capabilities, the latest drug therapies, and leading-edge surgical techniques for benign and malignant colorectal disease.

From treating cancer and inflammatory bowel disease to performing advanced diagnostics and robotic surgery, the colorectal team is one of the largest and most experienced in Pennsylvania. 

The division has an active clinical and basic science research program, including a research laboratory that has studied IBD for nearly 20 years. 

Organization profile

The Division of Colon and Rectal Surgery in the Department of Surgery at Penn State College of Medicine provides advanced and effective medical care, including state-of-the-art diagnostic capabilities, the latest drug therapies, and leading-edge surgical techniques for benign and malignant colorectal disease.

From treating cancer and inflammatory bowel disease to performing advanced diagnostics and robotic surgery, the colorectal team is one of the largest and most experienced in Pennsylvania. 

The division has an active clinical and basic science research program, including a research laboratory that has studied IBD for nearly 20 years. 

Fingerprint Dive into the research topics where Division of Colon and Rectal Surgery is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Crohn Disease Medicine & Life Sciences
Inflammatory Bowel Diseases Medicine & Life Sciences
Ulcerative Colitis Medicine & Life Sciences
Colonic Pouches Medicine & Life Sciences
Diverticulitis Medicine & Life Sciences
Colectomy Medicine & Life Sciences
Colitis Medicine & Life Sciences
Pouchitis Medicine & Life Sciences

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Research Output 1980 2019

1 Citation (Scopus)
Open Access
dopamine beta-monooxygenase
Dopamine beta-Hydroxylase
inflammatory bowel disease
Polymorphism
Inflammatory Bowel Diseases

Challenges in IBD Research: Precision Medicine

Denson, L. A., Curran, M., McGovern, D. P. B., Koltun, W. A., Duerr, R. H., Kim, S. C., Sartor, R. B., Sylvester, F. A., Abraham, C., de Zoeten, E. F., Siegel, C. A., Burns, R. M., Dobes, A. M., Shtraizent, N., Honig, G., Heller, C. A., Hurtado-Lorenzo, A. & Cho, J. H., May 16 2019, In : Inflammatory bowel diseases. 25, 2, p. S31-S39

Research output: Contribution to journalArticle

Open Access
Precision Medicine
Inflammatory Bowel Diseases
Research
Biomarkers
Technology

Gastrointestinal stromal tumors (GIST) of the anus: A single institution experience

Scow, J. S. & Mathis, K. L., Jan 1 2019, In : Turkish Journal of Gastroenterology. 30, 6, p. 576-577 2 p.

Research output: Contribution to journalLetter

Open Access
Gastrointestinal Stromal Tumors
Anal Canal
1 Citation (Scopus)

Multifocal Versus Conventional Unifocal Diverticulitis: A Comparison of Clinical and Transcriptomic Characteristics

Kline, B. P., Schieffer, K. M., Choi, C. S., Connelly, T., Chen, J., Harris, L., Deiling, S., Yochum, G. S. & Koltun, W. A., Nov 1 2019, In : Digestive Diseases and Sciences. 64, 11, p. 3143-3151 9 p.

Research output: Contribution to journalArticle

Diverticulitis
Recurrence
RNA

Post-Discharge Opioid Prescribing Patterns and Risk Factors in Patients Undergoing Elective Colon and Rectal Surgery Without Complications

Scow, J. S., Tomhave, N. M., Lovely, J. K., Spears, G. M., Huebner, M. & Larson, D. W., May 15 2019, In : Journal of Gastrointestinal Surgery. 23, 5, p. 1022-1029 8 p.

Research output: Contribution to journalArticle

Opioid Analgesics
Colon
Prescriptions
Colorectal Surgery
Pouchitis
Colonic Pouches
Ulcerative Colitis
Smoking

The Crohn’s disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells

Matthews, S. M., Eshelman, M. A., Berg, A. S., Koltun, W. A. & Yochum, G. S., Feb 2019, In : PloS one. 14, 2, e0212850.

Research output: Contribution to journalArticle

Open Access
Crohn disease
Polymorphism
Gene expression
Crohn Disease
single nucleotide polymorphism

Tristetraprolin targets Nos2 expression in the colonic epithelium

Eshelman, M. A., Matthews, S. M., Schleicher, E. M., Fleeman, R. M., Kawasawa, Y. I., Stumpo, D. J., Blackshear, P. J., Koltun, W. A., Ishmael, F. T. & Yochum, G. S., Dec 1 2019, In : Scientific reports. 9, 1, 14413.

Research output: Contribution to journalArticle

Open Access
Tristetraprolin
Epithelium
Epithelial Cells
3' Untranslated Regions
Colitis

3D Modeling of the Anorectum in Fistulous Crohn's Disease: Long Overdue

Koltun, W., Jun 1 2018, In : Annals of surgery. 267, 6, p. e108

Research output: Contribution to journalComment/debate

Crohn Disease
1 Citation (Scopus)

A differential host response to viral infection defines a subset of earlier-onset diverticulitis patients

Schieffer, K. M., Kline, B. P., Harris, L. R., Deiling, S., Koltun, W. & Yochum, G., Sep 1 2018, In : Journal of Gastrointestinal and Liver Diseases. 27, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

Diverticulitis
Virus Diseases
RNA Sequence Analysis
High-Throughput Nucleotide Sequencing
Viral Genes