Organization profile

Organization profile

The Division of Colon and Rectal Surgery in the Department of Surgery at Penn State College of Medicine provides advanced and effective medical care, including state-of-the-art diagnostic capabilities, the latest drug therapies, and leading-edge surgical techniques for benign and malignant colorectal disease.

From treating cancer and inflammatory bowel disease to performing advanced diagnostics and robotic surgery, the colorectal team is one of the largest and most experienced in Pennsylvania. 

The division has an active clinical and basic science research program, including a research laboratory that has studied IBD for nearly 20 years. 

Organization profile

The Division of Colon and Rectal Surgery in the Department of Surgery at Penn State College of Medicine provides advanced and effective medical care, including state-of-the-art diagnostic capabilities, the latest drug therapies, and leading-edge surgical techniques for benign and malignant colorectal disease.

From treating cancer and inflammatory bowel disease to performing advanced diagnostics and robotic surgery, the colorectal team is one of the largest and most experienced in Pennsylvania. 

The division has an active clinical and basic science research program, including a research laboratory that has studied IBD for nearly 20 years. 

Fingerprint Dive into the research topics where Division of Colon and Rectal Surgery is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

Crohn Disease Medicine & Life Sciences
Inflammatory Bowel Diseases Medicine & Life Sciences
Ulcerative Colitis Medicine & Life Sciences
Colonic Pouches Medicine & Life Sciences
Colectomy Medicine & Life Sciences
Diverticulitis Medicine & Life Sciences
Colitis Medicine & Life Sciences
Pouchitis Medicine & Life Sciences

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Research Output 1977 2020

Gastrointestinal hypoalgesia in inflammatory bowel disease

Coates, M. D., Soriano, C., Dalessio, S., Stuart, A., Walter, V., Koltun, W., Bernasko, N., Tinsley, A., Clarke, K. & Williams, E. D., Jan 1 2020, In : Annals of Gastroenterology. 33, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

Open Access
Inflammatory Bowel Diseases
Pain
Tertiary Care Centers
Fistula
Opiate Alkaloids

Matrix metalloproteinases cleave membrane-bound PD-L1 on CD90+ (myo-)fibroblasts in Crohn's disease and regulate Th1/Th17 cell responses

Aguirre, J. E., Beswick, E. J., Grim, C., Uribe, G., Tafoya, M., Chacon Palma, G., Samedi, V., McKee, R., Villeger, R., Fofanov, Y., Cong, Y., Yochum, G., Koltun, W., Powell, D. & Pinchuk, I. V., Jan 9 2020, In : International immunology. 32, 1, p. 57-68 12 p.

Research output: Contribution to journalArticle

Th17 Cells
Th1 Cells
Matrix Metalloproteinases
Crohn Disease
Fibroblasts
1 Citation (Scopus)
Open Access
dopamine beta-monooxygenase
Dopamine beta-Hydroxylase
inflammatory bowel disease
Polymorphism
Inflammatory Bowel Diseases
1 Citation (Scopus)

Challenges in IBD Research: Precision Medicine

Denson, L. A., Curran, M., McGovern, D. P. B., Koltun, W. A., Duerr, R. H., Kim, S. C., Sartor, R. B., Sylvester, F. A., Abraham, C., de Zoeten, E. F., Siegel, C. A., Burns, R. M., Dobes, A. M., Shtraizent, N., Honig, G., Heller, C. A., Hurtado-Lorenzo, A. & Cho, J. H., May 16 2019, In : Inflammatory bowel diseases. 25, 2, p. S31-S39

Research output: Contribution to journalArticle

Open Access
Precision Medicine
Inflammatory Bowel Diseases
Research
Biomarkers
Technology

Elevated colonic mucin expression correlates with extended time to surgery for ulcerative colitis patients

Eshelman, M. A., Jeganathan, N. A., Schieffer, K. M., Kline, B. P., Mendenhall, M., Deiling, S., Harris, L., Koltun, W. A. & Yochum, G. S., Jan 1 2019, In : Journal of Gastrointestinal and Liver Diseases. 28, 4, p. 405-413 9 p.

Research output: Contribution to journalArticle

Open Access
Mucins
Ulcerative Colitis
Colectomy
Gene Expression Profiling
Genes

Gastrointestinal stromal tumors (GIST) of the anus: A single institution experience

Scow, J. S. & Mathis, K. L., Jan 1 2019, In : Turkish Journal of Gastroenterology. 30, 6, p. 576-577 2 p.

Research output: Contribution to journalLetter

Open Access
Gastrointestinal Stromal Tumors
Anal Canal

Impact of the NaV1.8 variant, A1073V, on post-sigmoidectomy pain and electrophysiological function in rat sympathetic neurons

Coates, M. D., Kim, J. S., Carkaci-Salli, N., Vrana, K. E., Koltun, W. A., Puhl, H. L., Adhikary, S. D., Janicki, P. K. & Ruiz-Velasco, V., Dec 1 2019, In : Journal of neurophysiology. 122, 6, p. 2591-2600 10 p.

Research output: Contribution to journalArticle

Abdominal Pain
Postoperative Pain
Analgesics
Neurons
Pain
2 Citations (Scopus)

Multifocal Versus Conventional Unifocal Diverticulitis: A Comparison of Clinical and Transcriptomic Characteristics

Kline, B. P., Schieffer, K. M., Choi, C. S., Connelly, T., Chen, J., Harris, L., Deiling, S., Yochum, G. S. & Koltun, W. A., Nov 1 2019, In : Digestive Diseases and Sciences. 64, 11, p. 3143-3151 9 p.

Research output: Contribution to journalArticle

Diverticulitis
Recurrence
RNA

Post-Discharge Opioid Prescribing Patterns and Risk Factors in Patients Undergoing Elective Colon and Rectal Surgery Without Complications

Scow, J. S., Tomhave, N. M., Lovely, J. K., Spears, G. M., Huebner, M. & Larson, D. W., May 15 2019, In : Journal of Gastrointestinal Surgery. 23, 5, p. 1022-1029 8 p.

Research output: Contribution to journalArticle

Opioid Analgesics
Colon
Prescriptions
Colorectal Surgery
Pouchitis
Colonic Pouches
Ulcerative Colitis
Smoking