Eberly College of Science

Projects

Projects per year 1989 2022

• 53 Active
• 117 Finished

Projects per year

Search results

• Active

  Integrative Analysis of Metabolic Phenotypes (IAMP) Predoctoral Training Program

  Patterson, A. D. & Perdew, G. H.

  6/1/20 → 5/31/21

  Project: Research project

• Activities of yeast Ccr4-Not transcription factor complex

  Reese, J. C.

  6/1/20 → 3/31/21

  Project: Research project

• Acetyllysine Structure-Function Analysis by 13C Direct-Detect NMR Spectroscopy

  Showalter, S. A.

  5/1/20 → 3/31/21

  Project: Research project

• SHaping of Authentic Practices by Engaging in Modeling of A Topic with Teachers to Explore Research in Science (SHAPE MATTERS)

  Boal, A. K., Ropson, I., Yennawar, H. P., Yennawar, N. & HILL, K.

  5/1/20 → 3/31/21

  Project: Research project

• Translational control in neurogenesis by ZNF804A

  Mao, Y., MAO, Y., Shi, Y. & Shi, Y.

  4/1/20 → 1/31/22

  Project: Research project

• Unique targeting of PPAR?/? regulation for cancer prevention and therapy

  Patterson, A. D., Peters, J. M., PATTERSON, A. & PETERS, J.

  12/6/19 → 11/30/21

  Project: Research project

• R01: FXR and the Gut Microbiome as Modulators of Non-Alcoholic Fatty Liver Disease

  Patterson, A. D. & PATTERSON, A.

  9/23/19 → 5/31/21

  Project: Research project

• Structural and functional studies of RNase MRP RNP

  Krasilnikov, A. S. & KRASILNIKOV, A.

  9/16/19 → 7/31/21

  Project: Research project

• The role of Cytohesin dependent recycling in HGF stimulated migration and tissue repair

  Santy, L. C.

  9/15/19 → 8/31/21

  Project: Research project

• Development of Regioselective Alkene Dicarbofunctionalization Reactions

  Giri, R.

  9/1/19 → 5/31/21

  Project: Research project

• Modeling stress-induced, de novo epiallele architecture in the model Arabidopsis as a tractable entrypoint

  Mackenzie, S. & MACKENZIE, S.

  8/1/19 → 6/30/21

  Project: Research project

• Effects of histone ubiquitylation on nucleosome dynamics

  Lee, T.

  8/1/19 → 5/31/21

  Project: Research project

  • Nucleosomes
  • Ubiquitination
  • Histones
  • Histone Chaperones
  • Chromatin

• Structure and Mechanism of Transcription Factors in Pancreatic Beta Cells

  Showalter, S. A.

  7/1/19 → 6/30/21

  Project: Research project

• Diverse Transition-Metal and Free-Radical Chemistry Enabling 2'-Deoxyribonucleotide Production by Bacteria in Restrictive Environments

  Bollinger, Jr., J. M. & BOLLINGER, J.

  6/1/19 → 5/31/21

  Project: Research project

• Y Chromosome Evolution

  Makova, K. D. & MAKOVA, K.

  2/1/19 → 1/31/22

  Project: Research project

  • Y chromosome
  • Pongidae
  • Gorilla
  • genes
  • male sterility

• Implementing the Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL)

  Nekrutenko, A., Carey, V. J., LEEK, J., Morgan, M., Schatz, M., Taylor, J. P., Waldron, L. D., Goecks, J., Goecks, J., Morgan, M., Schatz, M., Carey, V. J., Goecks, J., LEEK, J., NEKRUTENKO, A., Waldron, L. D. & Waldron, L. D.

  9/21/18 → 6/30/21

  Project: Research project

  • Data Science
  • Informatics
  • Application programming interfaces (API)
  • Space platforms
  • Galaxies

• Structural studies of chromatin complexes

  Tan, S. & TAN, S.

  9/1/18 → 8/31/21

  Project: Research project

• Probing the Metabolism and Cellular Roles of 2',3'-Cyclic Nucleotide Monophosphate

  Weinert, E. & WEINERT, E.

  8/17/18 → 7/31/21

  Project: Research project

  • Metabolism
  • Cyclic Nucleotides
  • Bacteria
  • Biofilms
  • Messenger RNA

• Heterogeneity in bacterial quorum sensing during infection

  Miyashiro, T. I. & MIYASHIRO, T.

  8/1/18 → 7/31/21

  Project: Research project

  • quorum sensing
  • Vibrio fischeri
  • infection
  • bioluminescence
  • squid

• Eukaryotic Gene Regulation (EGR) Predoctoral Training Program

  Reese, J. C. & PUGH, F.

  7/1/18 → 6/30/21

  Project: Research project

• RNA folding and catalysis at the interface of biophysics and genomics

  Bevilacqua, P. C.

  5/1/18 → 4/30/21

  Project: Research project

  • RNA Folding
  • Biophysics
  • Catalysis
  • Genomics
  • Catalytic RNA

• Mechanisms of Mononuclear non-Heme-Iron Enzymes

  Krebs, C.

  5/1/18 → 4/30/21

  Project: Research project

• N-terminal acylation of Lipoproteins in Firmicutes

  Meredith, T. C.

  5/1/18 → 4/30/21

  Project: Research project

  • acylation
  • Firmicutes
  • lipoproteins
  • Enterococcus faecalis
  • Toll-like receptor 2

• Forward genetic prediction and testing of virulence loci in herpes simplex virus 1

  Szpara, M. L., SZPARA, M. & SZPARA, M.

  2/23/18 → 1/31/22

  Project: Research project

  • Human Herpesvirus 1
  • Genetic Testing
  • Virulence
  • Viral Proteins
  • Phenotype

• Dynamics of histone-DNA interaction

  Lee, T. & Lee, T. H.

  2/1/18 → 1/31/22

  Project: Research project

  • Histones
  • DNA
  • Chromatin Assembly and Disassembly
  • Nucleosomes
  • Gene Components

• Genome-wide structural organization of proteins within human gene regulatory complexes

  Mahony, S. A., MAHONY, S. A., PUGH, F., MAHONY, S. A. & PUGH, F.

  1/19/18 → 12/31/21

  Project: Research project

• Development of Cryo-EM/TEM Technologies for Small Protein and RNA Systems

  Hafenstein, S., Lindner, S. E., HAFENSTEIN, S. & LINDNER, S.

  1/1/18 → 12/31/21

  Project: Research project

• Statistical Models for Estimating and Projecting HIV/AIDS Epidemics

  Bao, L., BAO, L. & BAO, L.

  9/25/17 → 8/31/21

  Project: Research project

• Environmental Ah Receptor Ligand Impact on the Host-Microbiome Metabolic Axis

  Patterson, A. D. & PATTERSON, A.

  9/1/17 → 7/31/21

  Project: Research project

  • microbiome
  • hydrocarbons
  • ligands
  • fatty liver
  • receptors

• Physiology of ribosome rescue in bacteria

  Keiler, K. C.

  8/1/17 → 4/30/21

  Project: Research project

• Modeling the influence of translation-elongation kinetics on protein structure and function

  O'Brien, Jr., E. P. & O'BRIEN, E. P.

  8/1/17 → 7/31/21

  Project: Research project

  • Kinetics
  • Codon
  • Proteins
  • Silent Mutation
  • Cystic Fibrosis Transmembrane Conductance Regulator

• Epigenetic regulation of the circadian gene Per1 in age-related memory impairments

  Kwapis, J. & KWAPIS, J. L.

  7/15/17 → 5/31/21

  Project: Research project

  • Epigenomics
  • Memory
  • Long-Term Memory
  • histone deacetylase 3
  • Genes

• Tuning big data analysis infrastructure for HIV research

  Nekrutenko, A., Pond, S. K., Taylor, J. P., Schatz, M., NEKRUTENKO, A., Pond, S. K., NEKRUTENKO, A., Pond, S. K. & Schatz, M.

  6/26/17 → 5/31/21

  Project: Research project

  • Big Data
  • Data Analysis
  • HIV
  • Genome
  • Acquired Immunodeficiency Syndrome

• Radical Mechanisms of Iron-Sulfur Proteins

  Booker, S. J.

  4/1/17 → 3/31/21

  Project: Research project

  • Iron-Sulfur Proteins
  • S-Adenosylmethionine
  • Biosynthesis
  • Sulfur
  • Atoms

• Mechanistic study of pioneer factors

  Bai, L.

  1/1/17 → 12/31/21

  Project: Research project

  • Nucleosomes
  • Transcription Factors
  • Regulator Genes
  • Chromosomes
  • Binding Sites

• Mechanisms Governing Translational Regulation During Plasmodium Transmission

  Lindner, S. E.

  11/1/16 → 10/31/21

  Project: Research project

  • Plasmodium
  • Parasites
  • Sporozoites
  • Mosquito Vectors
  • Messenger RNA

• Emergent dynamics from network connectivity: a minimal model

  Curto, C. P.

  9/30/16 → 6/30/21

  Project: Research project

  • Neurons
  • Positive ions
  • Directed graphs
  • Brain
  • Neural networks

• Mapping the structural basis for mechanistic diversity in metalloenzyme superfamilies

  Boal, A. K.

  8/1/16 → 5/31/21

  Project: Research project

  • Scaffolds
  • Enzymes
  • Transition metals
  • Reengineering
  • Free Radicals

• VISION: ValIdated Systematic IntegratiON of epigenomic data

  Hardison, R. C., Blobel, G., BODINE, D., Taylor, J. P., Weiss, M., Zhang, Y., HARDISON, R., Schatz, M. & Zhang, Y.

  7/18/16 → 5/31/21

  Project: Research project

  • Genes
  • Gene expression
  • Stem cells
  • Chromosomes
  • Testing

• Gene Regulation from Long-Distance Chromosomal Interactions in Yeast

  Bai, L.

  5/6/16 → 4/30/21

  Project: Research project

• Mechanisms and Reprogramming of Iron/2-Oxoglutarate Desaturases and Oxacyclases

  Bollinger, Jr., J. M., KREBS, C., Krebs, C., BOLLINGER, J. & KREBS, C.

  4/15/16 → 3/31/21

  Project: Research project

  • Oxygenases
  • Ketoglutaric Acids
  • Iron
  • Halogenation
  • Carbon

• Penn State Biomedical Big Data to Knowledge (B2D2K) Training Program

  Li, R., Ritchie, M. D., HONAVAR, V., BROACH, J., HONAVAR, V., BROACH, J. & Honavar, V. G.

  4/1/16 → 3/31/21

  Project: Research project

  • Big data
  • Health
  • Data Science
  • Informatics
  • Bioinformatics

• From Cells to Societies: Mechanisms by Which Microbial Parasites Control Host Phenotypes

  Hanks, E. M., Hughes, D. P. & Chen, D. Z.

  2/1/16 → 1/31/22

  Project: Research project

  • Formicidae
  • parasites
  • phenotype
  • group behavior
  • insect trails

• Genomic Architecture of LGL Leukemia

  Hardison, R. C., Loughran, T. P., HARDISON, R., HARDISON, R. & Loughran, T. P.

  12/1/15 → 11/30/21

  Project: Research project

  • Large Granular Lymphocytic Leukemia
  • Genome
  • Phenotype
  • Mutation
  • Genomic Structural Variation

• Center for Complex Data to Knowledge in Drug Abuse and HIV Behavioral Science

  Li, R., Collins, L. M., LANZA, S., COLLINS, L., Bray, B., Lanza, S. T., Lanza, S. T. & Li, R.

  9/1/15 → 7/31/21

  Project: Research project

  • Substance-Related Disorders
  • HIV
  • Behavioral Sciences
  • Research Personnel
  • Software

• The Dynamics of Mitochondrial Mutations

  Makova, K. D., Nielsen, R., Nielsen, R., Nielsen, R., MAKOVA, K. & Nielsen, R.

  8/1/15 → 3/31/21

  Project: Research project

  • mitochondrial DNA
  • mutation
  • somatic mutation
  • oocytes
  • alleles

• Computation, Bioinformatics, and Statistics (CBIOS) Training Program

  Makova, K. D., Shashikant, C. S., Chiaromonte, F., Shashikant, C. S., Schaeffer, S. W., Ghosh, D., Chiaromonte, F., MAKOVA, K., SHASHIKANT, C., SHASHIKANT, C. S., Ghosh, D., Hardison, R. C., HARDISON, R., Shashikant, C. S., HARDISON, R., HARDISON, R., SHASHIKANT, C. S. & HARDISON, R.

  7/1/13 → 6/30/21

  Project: Research project

  • education programs
  • bioinformatics
  • statistics
  • training program
  • trainee

• GABAergic Control of Depression Related Brain States

  Luscher, B. & LUSCHER, B.

  4/18/13 → 8/31/21

  Project: Research project

  • Major Depressive Disorder
  • Interneurons
  • Antidepressive Agents
  • Depression
  • Brain

• Physiological Regulation of Proinsulin Quality and Quantity Control in the Pancre

  Cavener, D. R., CAVENER, D. R. & CAVENER, D. R.

  9/27/10 → 6/30/21

  Project: Research project

  • Proinsulin
  • Quality Control
  • Insulin Secretion
  • Endoplasmic Reticulum
  • Insulin

• Using Drosophila Neurons to Identify Mechanisms that Control Microtubule Polarity

  Rolls, M., ROLLS, M. & ROLLS, M.

  5/1/10 → 4/30/21

  Project: Research project

  • Microtubules
  • Drosophila
  • Neurons
  • Dendrites
  • Axons