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Research Output 1975 2019

2019

Abstracts of Presentations at the Association of Clinical Scientists 139th Meeting Hershey, PA, May 15-18, 2019

Donaldson, K., Buchanich, J. M., Grigson, P. S., Deneke, E., Vrana, K. E., Sacks, D. B., Kuehn, G. J., Cardamone, D., Pesce, A., Smiley, S., Nickley, J., Krock, K., Thomas, R., Wilkerson, M. L., Farag, H. A., Challa, S. R., Tice, A. M., Wolk, D. M., Prichard, J., Grant, M. L. & 102 others, Regmi, S., Kerbacher, B., Quinton, L. E., Tice, A. M., Olson, J., Haynes, A., Yu, E., McCully, K. S., Assi, J., Wong, M., Zarrin-Khameh, N., Nifong, T. P., Hawker, C. D., Carlton, G. T., Rivera, J. M., Foulis, P. R., Zuraw, A., Morlote, D., Peker, D., Reddy, V., Harada, S., Crutchfield, C., Zander, D., Barbhuiya, M. A., Pederson, E. C., Straub, M. L., Scott, S. C., Neibauer, T. L., Salter, W. F., Creer, M. H., Zhu, Y., Bornhorst, J. A., Theobald, J. P., Algeciras-Schimnich, A., Cao, L., Knox, J., Hardy, R., Texas, H. J., McGuire, M. F., Hunter, R. L., Brown, R. E., Hicks, J., Cai, Z., Brown, R. E., Ali, Y., Cheng, K. C., Katz, S. R., Ding, Y., Vanselow, D. J., Yakovlev, M. A., Lin, A. Y., Clark, D. P., Vargas, P., Xin, X., Copper, J. E., Canfield, V. A., Ang, K. C., Wang, Y., Xiao, X., De Carlo, F., van Rossum, D. B., La Rivière, P. J., Newell, J., Hossler, C., Roche, M., Warrick, J., Phaeton, R., Kesterson, J., Myers, C., Barrios, R., Mintz, P., Robyak, K., Hamilton, C., McGhee, P., Pederson, C., Straub, M., Scott, S., Neibauer, T., Salter, W., Robyak, K., Singh, N., Morlote, D., Vnencak-Jones, C., Yemelyanova, A., Harada, S., Shah, M., Moghadamtousi, S. Z., Lan, C., Duose, D., Hu, P., Esquenazi, Y., Luthra, R., Ballester, L. Y., Koenig, A. N., Liu, C. G., Zhang, J., Kalia, A., Al-Habib, A., Van Arsdall, M., Dhingra, S., Patel, K. & Tatevian, N., May 1 2019, In : Annals of clinical and laboratory science. 49, 3, p. 403-416 14 p.

Research output: Contribution to journalArticle

An R package for model fitting, model selection and the simulation for longitudinal data with dropout missingness

Xu, C., Li, Z., Xue, Y., Zhang, L. & Wang, M., Oct 21 2019, In : Communications in Statistics: Simulation and Computation. 48, 9, p. 2812-2829 18 p.

Research output: Contribution to journalArticle

Drop out
Model Fitting
Longitudinal Data
Model Selection
Weighted Estimating Equations
1 Citation (Scopus)
Open Access
dopamine beta-monooxygenase
Dopamine beta-Hydroxylase
inflammatory bowel disease
Polymorphism
Inflammatory Bowel Diseases
5 Citations (Scopus)

Association between DNA methylation in obesity-related genes and body mass index percentile in adolescents

He, F., Berg, A., Imamura, Y., Bixler, E., Fernandez-Mendoza, J., Whitsel, E. A. & Liao, D., Dec 1 2019, In : Scientific reports. 9, 1, 2079.

Research output: Contribution to journalArticle

DNA Methylation
Body Mass Index
Obesity
Genes
Pediatric Obesity
35 Citations (Scopus)

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

23andMe Research Team, HUNT All-In Psychiatry, Liu, M., Jiang, Y., Wedow, R., Li, Y., Brazel, D. M., Chen, F., Datta, G., Davila-Velderrain, J., McGuire, D., Tian, C., Zhan, X., Agee, M., Alipanahi, B., Auton, A., Bell, R. K., Bryc, K., Elson, S. L., Fontanillas, P. & 32 others, Furlotte, N. A., Hinds, D. A., Hromatka, B. S., Huber, K. E., Kleinman, A., Litterman, N. K., McIntyre, M. H., Mountain, J. L., Northover, C. A. M., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Shringarpure, S., Tian, C., Tung, J. Y., Vacic, V., Wilson, C. H., Pitts, S. J., Mitchell, A., Skogholt, A. H., Winsvold, B. S., Sivertsen, B., Stordal, E., Morken, G., Kallestad, H., Heuch, I., Zwart, J. A., Fjukstad, K. K., Pedersen, L. M., Gabrielsen, M. E., Johnsen, M. B. & Liu, D., Feb 1 2019, In : Nature Genetics. 51, 2, p. 237-244 8 p.

Research output: Contribution to journalLetter

Tobacco Use
Alcohols
Tobacco Use Cessation
Genetic Association Studies
Synaptic Transmission
1 Citation (Scopus)
Acute Myeloid Leukemia
Respiratory Insufficiency
Non-Hodgkin's Lymphoma
Autopsy
Pathology
1 Citation (Scopus)

Characterization of histone deacetylase expression within in vitro and in vivo bladder cancer model systems

Buckwalter, J. M., Chan, W., Shuman, L., Wildermuth, T., Ellis-Mohl, J., Walter, V., Warrick, J. I., Wu, X. R., Kaag, M., Raman, J. D. & Degraff, D. J., May 2 2019, In : International journal of molecular sciences. 20, 10, 2599.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylases
bladder
Polymerase chain reaction
Urinary Bladder Neoplasms
cancer
1 Citation (Scopus)

Circulating microRNAs in plasma among men with low-grade and high-grade prostate cancer at prostate biopsy

McDonald, A. C., Vira, M., Walter, V., Shen, J., Raman, J. D., Sanda, M. G., Patil, D. & Taioli, E., Jun 15 2019, In : Prostate. 79, 9, p. 961-968 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Biopsy
Neoplasm Grading
Prostate-Specific Antigen

Differential impact of co-expressed SP-A1/SP-A2 protein on AM miRNome; Sex differences

Thorenoor, N., Imamura, Y., Gandhi, C., Zhang, X. & Floros, J., Jan 1 2019, In : Frontiers in immunology. 10, AUG, 1960.

Research output: Contribution to journalArticle

Open Access
Alveolar Macrophages
varespladib methyl
Sex Characteristics
Pulmonary Surfactant-Associated Protein A
Oxidative Stress
4 Citations (Scopus)

Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis

Liu, Z., Yee, P. P., Wei, Y., Liu, Z., Imamura, Y. & Li, W., Mar 1 2019, In : Journal of Cell Science. 132, 5, jcs225714.

Research output: Contribution to journalArticle

Open Access
Glioma
Carcinogenesis
Neoplasms
Glioblastoma
Growth
1 Citation (Scopus)

Early-life stress impairs postnatal oligodendrogenesis and adult emotional behaviour through activity-dependent mechanisms

Teissier, A., Le Magueresse, C., Olusakin, J., Andrade da Costa, B. L. S., De Stasi, A. M., Bacci, A., Imamura Kawasawa, Y., Vaidya, V. A. & Gaspar, P., Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
Oligodendroglia
Psychological Stress
Prefrontal Cortex
Neurons
Immediate-Early Genes
Open Access
Students
evaluation
student
Nonparametric Statistics
Medical Students

Empirical-likelihood-based criteria for model selection on marginal analysis of longitudinal data with dropout missingness

Chen, C., Shen, B., Zhang, L., Xue, Y. & Wang, M., Sep 1 2019, In : Biometrics. 75, 3, p. 950-965 16 p.

Research output: Contribution to journalArticle

dropouts
Information Criterion
Empirical Likelihood
Drop out
Longitudinal Data
1 Citation (Scopus)

Excess Dietary Zinc Intake in Neonatal Mice Causes Oxidative Stress and Alters Intestinal Host–Microbe Interactions

Podany, A., Rauchut, J., Wu, T., Imamura, Y., Wright, J., Lamendella, R., Soybel, D. & Kelleher, S. L., Feb 1 2019, In : Molecular Nutrition and Food Research. 63, 3, 1800947.

Research output: Contribution to journalArticle

Zinc
neonates
Oxidative Stress
oxidative stress
zinc
6 Citations (Scopus)

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

CHD Exome+ Consortium, Consortium for Genetics of Smoking Behaviour, Brazel, D. M., Jiang, Y., Hughey, J. M., Turcot, V., Zhan, X., Gong, J., Batini, C., Weissenkampen, J. D., Liu, M. Z., Surendran, P., Young, R., Barnes, D. R., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Kontto, J., Perola, M. & 32 others, Caslake, M., de Craen, A. J. M., Trompet, S., Uria-Nickelsen, M., Malarstig, A., Reily, D. F., Hoek, M., Vogt, T., Jukema, J. W., Sattar, N., Ford, I., Packard, C. J., Alam, D. S., Majumder, A. A. S., Di Angelantonio, E., Chowdhury, R., Amouyel, P., Arveiler, D., Blankenberg, S., Ferrières, J., Kee, F., Kuulasmaa, K., Müller-Nurasyid, M., Veronesi, G., Virtamo, J., EPIC-CVD Consortium, C., Frossard, P., Nordestgaard, B. G., Saleheen, D., Danesh, J., Butterworth, A. S. & Liu, D., Jun 1 2019, In : Biological Psychiatry. 85, 11, p. 946-955 10 p.

Research output: Contribution to journalArticle

Exome
Meta-Analysis
Smoking
Alcohols
Phenotype
2 Citations (Scopus)

Gene Expression Subtype Predicts Nodal Metastasis and Survival in Human Papillomavirus–Negative Head and Neck Cancer

Zevallos, J. P., Mazul, A. L., Walter, V. & Hayes, D. N., Jan 1 2019, In : Laryngoscope. 129, 1, p. 154-161 8 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Squamous Cell Carcinoma
Neoplasm Metastasis
Gene Expression
Survival

Genetic variants implicate dual oxidase-2 in familial and sporadic nonmedullary thyroid cancer

Bann, D. V., Jin, Q., Sheldon, K. E., Houser, K. R., Nguyen, L., Warrick, J. I., Baker, M. J., Broach, J. R., Gerhard, G. S. & Goldenberg, D., Nov 1 2019, In : Cancer Research. 79, 21, p. 5490-5499 10 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Penetrance
Oxidoreductases
Exome
Hydrogen Peroxide
2 Citations (Scopus)

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

Worley, B. L., Kim, Y. S., Mardini, J., Zaman, R., Leon, K. E., Vallur, P. G., Nduwumwami, A., Warrick, J. I., Timmins, P. F., Kesterson, J. P., Phaëton, R., Lee, N. Y., Walter, V., Endres, L., Mythreye, K., Aird, K. M. & Hempel, N., Jul 2019, In : Redox Biology. 25, 101051.

Research output: Contribution to journalArticle

Glutathione Peroxidase
Ovarian Neoplasms
Oxidation-Reduction
Ascites
Adenocarcinoma

HBV induces different responses of the hepatocytes and oval cells during HBV-related hepatic cirrhosis

Zhang, L., Chen, Y., Zhang, L. J., Wang, M., Chang, D. L., Wan, W. W., Zhang, B. X., Zhang, W. G. & Chen, X. P., Feb 28 2019, In : Cancer Letters. 443, p. 47-55 9 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Liver Cirrhosis
Hepatocytes
Transgenic Mice
Fibrosis

Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer

Osei-Amponsa, V., Buckwalter, J. M., Shuman, L., Zheng, Z., Yamashita, H., Walter, V., Wildermuth, T., Ellis-Mohl, J., Liu, C., Warrick, J. I., Shantz, L. M., Feehan, R. P., Al-Ahmadie, H., Mendelsohn, C., Raman, J. D., Kaestner, K. H., Wu, X. R. & DeGraff, D. J., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Loss of Heterozygosity
Urinary Bladder Neoplasms
Urothelium
Inborn Genetic Diseases
DNA

Increased burden of rare deleterious variants of the KCNQ1 gene in patients with large‑vessel ischemic stroke

Janicki, P., Eyileten, C., Ruiz-Velasco, V., Pordzik, J., Czlonkowska, A., Kurkowska-Jastrzebska, I., Sugino, S., Imamura, Y., Mirowska-Guzel, D. & Postula, M., Apr 1 2019, In : Molecular medicine reports. 19, 4, p. 3263-3272 10 p.

Research output: Contribution to journalArticle

Platelets
Genes
Stroke
Quality control
Blood Platelets
21 Citations (Scopus)

Intratumoral Heterogeneity of Bladder Cancer by Molecular Subtypes and Histologic Variants [Figure presented]

Warrick, J., Sjödahl, G., Kaag, M. G., Raman, J., Merrill, S., Shuman, L., Chen, G., Walter, V. & Degraff, D., Jan 1 2019, In : European Urology. 75, 1, p. 18-22 5 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Neoplasms
Histology
Selection Bias
Carcinoma
4 Citations (Scopus)

Measuring the reproducibility and quality of Hi-C data

Yardımcı, G. G., Ozadam, H., Sauria, M. E. G., Ursu, O., Yan, K. K., Yang, T., Chakraborty, A., Kaul, A., Lajoie, B. R., Song, F., Zhan, Y., Ay, F., Gerstein, M., Kundaje, A., Li, Q., Taylor, J., Yue, F., Dekker, J. & Noble, W. S., Mar 19 2019, In : Genome biology. 20, 1, 57.

Research output: Contribution to journalArticle

reproducibility
Noise
Benchmarking
DNA Replication
Practice Guidelines
2 Citations (Scopus)

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, Erzurumluoglu, A. M., Liu, M., Jackson, V. E., Barnes, D. R., Datta, G., Melbourne, C. A., Young, R., Batini, C., Surendran, P., Jiang, T., Adnan, S. D., Afaq, S., Agrawal, A., Altmaier, E., Antoniou, A. C., Asselbergs, F. W., Baumbach, C., Bierut, L., Bertelsen, S. & 31 others, Boehnke, M., Bots, M. L., Brazel, D. M., Chambers, J. C., Chang-Claude, J., Chen, C., Corley, J., Chou, Y. L., David, S. P., de Boer, R. A., de Leeuw, C. A., Dennis, J. G., Dominiczak, A. F., Dunning, A. M., Easton, D. F., Eaton, C., Elliott, P., Evangelou, E., Faul, J. D., Foroud, T., Goate, A., Gong, J., Grabe, H. J., Haessler, J., Haiman, C., Hallmans, G., Hammerschlag, A. R., Harris, S. E., Hattersley, A., Heath, A. & Liu, D., Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Open Access
Genetic Loci
Meta-Analysis
Smoking
Nucleotides
Exome
1 Citation (Scopus)

Methods for the Analysis and Interpretation for Rare Variants Associated with Complex Traits

Weissenkampen, J. D., Jiang, Y., Eckert, S., Jiang, B., Li, B. & Liu, D., Apr 1 2019, In : Current protocols in human genetics. 101, 1, e83.

Research output: Contribution to journalArticle

Exome
Precision Medicine
DNA Sequence Analysis
Sequence Analysis
Meta-Analysis
Papillary Carcinoma
Recurrence
Neoplasms
Proportional Hazards Models
Neoplasm Grading
1 Citation (Scopus)

Molecular characterization of tumors meeting diagnostic criteria for the non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)

Pool, C., Walter, V., Bann, D., Goldenberg, D., Broach, J., Hennessy, M., Cottrill, E., Washburn, E., Williams, N., Crist, H., Imamura, Y. & Warrick, J., Mar 11 2019, In : Virchows Archiv. 474, 3, p. 341-351 11 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Factor IX
Neoplasms
Adenoma
RNA Sequence Analysis

O-GlcNAcylation alters the selection of mRNAs for translation and promotes 4E-BP1 dependent mitochondrial dysfunction in the retina

Dierschke, S. K., Miller, W. P., Favate, J. S., Shah, P., Kawasawa, Y. I., Salzberg, A. C., Kimball, S. R., Jefferson, L. S. & Dennis, M. D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 14, p. 5508-5520 13 p.

Research output: Contribution to journalArticle

Protein Biosynthesis
Retina
Messenger RNA
Ribosomes
Eukaryotic Initiation Factors
5 Citations (Scopus)

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, InterAct & ReproGen Consortium, Mar 1 2019, In : Nature Genetics. 51, 3, p. 452-469 18 p.

Research output: Contribution to journalArticle

Body Fat Distribution
Homeostasis
Lipids
Fats
Genes

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x)

CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, EPIC InterAct Consortium, INTERVAL Study, ReproGen Consortium, T2D-Genes Consortium, The MAGIC Investigators & Understanding Society Scientific Group, Jan 1 2019, (Accepted/In press) In : Nature Genetics.

Research output: Contribution to journalComment/debate

Open Access
Energy Intake
Energy Metabolism
Body Mass Index
Obesity
Proteins
1 Citation (Scopus)

RAG1 high expression associated with IKZF1 dysfunction in adult B-cell acute lymphoblastic leukemia

Han, Q., Ma, J., Gu, Y., Song, H., Kapadia, M., Kawasawa, Y. I., Dovat, S., Song, C. & Ge, Z., Jan 1 2019, In : Journal of Cancer. 10, 16, p. 3842-3850 9 p.

Research output: Contribution to journalArticle

Open Access
Precursor Cell Lymphoblastic Leukemia-Lymphoma
B-Lymphocytes
Genetic Recombination
Clonal Evolution
Carcinogenesis

Repository corticotropin injection reverses critical elements of the TLR9/B cell receptor activation response in human B cells in vitro

Olsen, N., Benko, A. L., McAloose, C. A., Becker, P. M., Wright, D., Sunyer, T., Imamura, Y. & Kovacs, W., Apr 1 2019, In : Clinical Immunology. 201, p. 70-78 9 p.

Research output: Contribution to journalArticle

Adrenocorticotropic Hormone
B-Lymphocytes
Messenger RNA
Injections
Immunoglobulin M
6 Citations (Scopus)

Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis

The ITALSGEN Consortium & The International ALS Genomics Consortium, Apr 2019, In : Annals of Neurology. 85, 4, p. 470-481 12 p.

Research output: Contribution to journalArticle

Open Access
Amyotrophic Lateral Sclerosis
Genome-Wide Association Study
Linkage Disequilibrium
Random Allocation
Smoking
2 Citations (Scopus)

Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

Buj, R., Chen, C. W., Dahl, E. S., Leon, K. E., Kuskovsky, R., Maglakelidze, N., Navaratnarajah, M., Zhang, G., Doan, M. T., Jiang, H., Zaleski, M., Kutzler, L., Lacko, H., Lu, Y., Mills, G. B., Gowda, R., Robertson, G., Warrick, J., Herlyn, M., Imamura, Y. & 4 others, Kimball, S., Degraff, D., Snyder, N. W. & Aird, K., Aug 20 2019, In : Cell Reports. 28, 8, p. 1971-1980.e8

Research output: Contribution to journalArticle

Open Access
Nucleotides
Metabolism
Carcinogenesis
Up-Regulation
Neoplasms

Targeting IDH1 as a prosenescent therapy in high-grade serous ovarian cancer

Dahl, E. S., Buj, R., Leon, K. E., Newell, J. M., Imamura, Y., Bitler, B. G., Snyder, N. W. & Aird, K. M., Aug 1 2019, In : Molecular Cancer Research. 17, 8, p. 1710-1720 11 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Carcinoma
Therapeutics
Neoplasms
Epigenomics

Tristetraprolin targets Nos2 expression in the colonic epithelium

Eshelman, M. A., Matthews, S. M., Schleicher, E. M., Fleeman, R. M., Kawasawa, Y. I., Stumpo, D. J., Blackshear, P. J., Koltun, W. A., Ishmael, F. T. & Yochum, G. S., Dec 1 2019, In : Scientific reports. 9, 1, 14413.

Research output: Contribution to journalArticle

Open Access
Tristetraprolin
Epithelium
Epithelial Cells
3' Untranslated Regions
Colitis

VPS37A directs ESCRT recruitment for phagophore closure

Takahashi, Y., Liang, X., Hattori, T., Tang, Z., He, H., Chen, H., Liu, X., Abraham, T., Imamura-Kawasawa, Y., Buchkovich, N. J., Young, M. M. & Wang, H. G., Oct 7 2019, In : The Journal of cell biology. 218, 10, p. 3336-3354 19 p.

Research output: Contribution to journalArticle

Open Access
Endosomal Sorting Complexes Required for Transport
Clustered Regularly Interspaced Short Palindromic Repeats
Multivesicular Bodies
Ubiquitin
Epidermal Growth Factor Receptor

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

Pajtler, K. W., Wei, Y., Okonechnikov, K., Silva, P. B. G., Vouri, M., Zhang, L., Brabetz, S., Sieber, L., Gulley, M., Mauermann, M., Wedig, T., Mack, N., Imamura Kawasawa, Y., Sharma, T., Zuckermann, M., Andreiuolo, F., Holland, E., Maass, K., Körkel-Qu, H., Liu, H. K. & 13 others, Sahm, F., Capper, D., Bunt, J., Richards, L. J., Jones, D. T. W., Korshunov, A., Chavez, L., Lichter, P., Hoshino, M., Pfister, S. M., Kool, M., Li, W. & Kawauchi, D., Dec 1 2019, In : Nature communications. 10, 1, 3914.

Research output: Contribution to journalArticle

Open Access
NFI Transcription Factors
Ependymoma
subgroups
Carcinogenesis
Fusion reactions
2018
4 Citations (Scopus)

Activity-Induced Regulation of Synaptic Strength through the Chromatin Reader L3mbtl1

Mao, W., Salzberg, A. C., Uchigashima, M., Hasegawa, Y., Hock, H., Watanabe, M., Akbarian, S., Kawasawa, Y. I. & Futai, K., Jun 12 2018, In : Cell Reports. 23, 11, p. 3209-3222 14 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Chromatin
Tumors
Brain
Histone Code
3 Citations (Scopus)

Adaptive-weight burden test for associations between quantitative traits and genotype data with complex correlations

Wu, X., Guan, T., Liu, D. J., Novelo, L. G. L. & Bandyopadhyay, D., Sep 2018, In : Annals of Applied Statistics. 12, 3, p. 1558-1582 25 p.

Research output: Contribution to journalArticle

Genotype
Genes
Glucose
Throughput
Statistics
4 Citations (Scopus)
Interleukin-4
Dendritic Cells
Malaria
Interleukin-12
Proteins
1 Citation (Scopus)

A possible role for platelet-activating factor receptor in amyotrophic lateral sclerosis treatment

Briones, M. R. S., Snyder, A., Ferreira, R. C., Neely, E. B., Connor, J. & Broach, J., Feb 6 2018, In : Frontiers in Neurology. 9, FEB, 39.

Research output: Contribution to journalArticle

Amyotrophic Lateral Sclerosis
Platelet Activating Factor
ginkgolide B
Interleukin-18
WEB 2086
6 Citations (Scopus)

B-Cell-Intrinsic Type 1 Interferon Signaling Is Crucial for Loss of Tolerance and the Development of Autoreactive B Cells

Domeier, P. P., Chodisetti, S. B., Schell, S. L., Imamura, Y., Fasnacht, M. J., Soni, C. & Rahman, Z., Jul 10 2018, In : Cell Reports. 24, 2, p. 406-418 13 p.

Research output: Contribution to journalArticle

Interferon Type I
B-Lymphocytes
Cells
Germinal Center
Antibodies
2 Citations (Scopus)

CD4 T cells control development and maintenance of brain-resident CD8 T cells during polyomavirus infection

Mockus, T. E., Shwetank, Lauver, M. D., Ren, H. M., Netherby, C. S., Salameh, T., Kawasawa, Y. I., Yue, F., Broach, J. R. & Lukacher, A. E., Oct 2018, In : PLoS pathogens. 14, 10, e1007365.

Research output: Contribution to journalArticle

Polyomavirus Infections
Maintenance
T-Lymphocytes
Brain
JC Virus

Dynamic chromatin accessibility unveils a regulatory landscape in early embryogenesis in human

Liu, T. & Yue, F., Dec 1 2018, In : Biology of reproduction. 99, 6, p. 1116-1118 3 p.

Research output: Contribution to journalComment/debate

Chromatin
Embryonic Development
10 Citations (Scopus)

Effectiveness of Practices to Support Appropriate Laboratory Test Utilization

Rubinstein, M., Hirsch, R., Bandyopadhyay, K., Madison, B., Taylor, T., Ranne, A., Linville, M., Donaldson, K., Lacbawan, F. & Cornish, N., Feb 17 2018, In : American journal of clinical pathology. 149, 3, p. 197-221 25 p.

Research output: Contribution to journalReview article

Medical Order Entry Systems
Reflex
Length of Stay
Clinical Decision Support Systems
Education
21 Citations (Scopus)

Enhancing Hi-C data resolution with deep convolutional neural network HiCPlus

Zhang, Y., An, L., Xu, J., Zhang, B., Zheng, W. J., Hu, M., Tang, J. & Yue, F., Dec 1 2018, In : Nature communications. 9, 1, 750.

Research output: Contribution to journalArticle

sequencing
Genes
Neural networks
Chromatin
chromatin
9 Citations (Scopus)
Manuscripts
Neoplasms
Chromosomes
Uveal melanoma
2 Citations (Scopus)
Malpractice
Climate
Thyroid Neoplasms
climate
incidence
5 Citations (Scopus)

Exosomes impact survival to radiation exposure in cell line models of nervous system cancer

Mrowczynski, O. D., Madhankumar, A., Sundstrom, J., Zhao, Y., Imamura, Y., Slagle-Webb, B., Mau, C., Payne, R. A., Rizk, E., Zacharia, B. & Connor, J., Nov 1 2018, In : Oncotarget. 9, 90, p. 36083-36101 19 p.

Research output: Contribution to journalArticle

Exosomes
Nervous System
Cell Line
Survival
Neoplasms