• 500 University Drive

    17033 Hershey

    United States

Research Output 1975 2019

2018
21 Citations (Scopus)

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

The Geisinger-Regeneron DiscovEHR Collaboration, The VA Million Veteran Program, Global Lipids Genetics Consortium & Myocardial Infarction Genetics (MIGen) Consortium, Nov 1 2018, In : Nature Genetics. 50, 11, p. 1514-1523 10 p.

Research output: Contribution to journalArticle

Veterans
Lipids
Electronic Health Records
Abdominal Aortic Aneurysm
Hispanic Americans
62 Citations (Scopus)

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

ITALSGEN Consortium, Genomic Translation for ALS Care (GTAC) Consortium, ALS Sequencing Consortium, NYGC ALS Consortium, Answer ALS Foundation, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, SLAGEN Consortium, French ALS Consortium & Project MinE ALS Sequencing Consortium, Mar 21 2018, In : Neuron. 97, 6, p. 1268-1283.e6

Research output: Contribution to journalArticle

Kinesin
Genome
Mutation
Genes
Genome-Wide Association Study
33 Citations (Scopus)

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell Reports. 23, 1, p. 194-212.e6

Research output: Contribution to journalArticle

Squamous Cell Carcinoma
MicroRNAs
Mutation
Epithelial Cells
Squamous Cell Neoplasms
6 Citations (Scopus)

GM-CSF overexpression after influenza a virus infection prevents mortality and moderates M1-like airway monocyte/macrophage polarization

Halstead, E. S., Umstead, T. M., Davies, M. L., Imamura, Y., Silveyra, P., Howyrlak, J., Yang, L., Guo, W., Hu, S., Hewage, E. K. & Chroneos, Z., Jan 5 2018, In : Respiratory research. 19, 1, 1 p.

Research output: Contribution to journalArticle

Virus Diseases
Granulocyte-Macrophage Colony-Stimulating Factor
Orthomyxoviridae
Monocytes
Macrophages

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

Worley, B. L., Kim, Y. S., Mardini, J., Zaman, R., Leon, K. E., Vallur, P. G., Nduwumwami, A., Warrick, J., Timmins, P. F., Kesterson, J., Phaeton, R., Lee, N. Y., Walter, V., Endres, L., Mythreye, K., Aird, K. & Hempel, N., Jan 1 2018, (Accepted/In press) In : Redox Biology.

Research output: Contribution to journalArticle

Glutathione Peroxidase
Ovarian Neoplasms
Oxidation-Reduction
Ascites
Adenocarcinoma
Hepatitis C Antibodies
Hepacivirus
Tissue Donors
RNA
Kidney
Open Access
Inflammatory Bowel Diseases
Phenotype
Voltage-Gated Sodium Channels
Abdominal Pain
Single Nucleotide Polymorphism
21 Citations (Scopus)

Integrative detection and analysis of structural variation in cancer genomes

Dixon, J. R., Xu, J., Dileep, V., Zhan, Y., Song, F., Le, V. T., Yardımcı, G. G., Chakraborty, A., Bann, D. V., Wang, Y., Clark, R., Zhang, L., Yang, H., Liu, T., Iyyanki, S., An, L., Pool, C., Sasaki, T., Rivera-Mulia, J. C., Ozadam, H. & 17 others, Lajoie, B. R., Kaul, R., Buckley, M., Lee, K., Diegel, M., Pezic, D., Ernst, C., Hadjur, S., Odom, D. T., Stamatoyannopoulos, J. A., Broach, J. R., Hardison, R. C., Ay, F., Noble, W. S., Dekker, J., Gilbert, D. M. & Yue, F., Oct 1 2018, In : Nature Genetics. 50, 10, p. 1388-1398 11 p.

Research output: Contribution to journalArticle

Genome
Genomic Structural Variation
DNA Replication Timing
Neoplasms
Sequence Deletion
33 Citations (Scopus)

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

BrainSpan Consortium, PsychENCODE Consortium & PsychENCODE Developmental Subgroup, Dec 14 2018, In : Science. 362, 6420, 1264.

Research output: Contribution to journalArticle

Open Access
Human Development
Epigenomics
Brain
Gene Regulatory Networks
Genes
29 Citations (Scopus)

Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

George, J., Walter, V., Peifer, M., Alexandrov, L. B., Seidel, D., Leenders, F., Maas, L., Müller, C., Dahmen, I., Delhomme, T. M., Ardin, M., Leblay, N., Byrnes, G., Sun, R., De Reynies, A., McLeer-Florin, A., Bosco, G., Malchers, F., Menon, R., Altmüller, J. & 42 others, Becker, C., Nürnberg, P., Achter, V., Lang, U., Schneider, P. M., Bogus, M., Soloway, M. G., Wilkerson, M. D., Cun, Y., McKay, J. D., Moro-Sibilot, D., Brambilla, C. G., Lantuejoul, S., Lemaitre, N., Soltermann, A., Weder, W., Tischler, V., Brustugun, O. T., Lund-Iversen, M., Helland, Å., Solberg, S., Ansén, S., Wright, G., Solomon, B., Roz, L., Pastorino, U., Petersen, I., Clement, J. H., Sänger, J., Wolf, J., Vingron, M., Zander, T., Perner, S., Travis, W. D., Haas, S. A., Olivier, M., Foll, M., Büttner, R., Hayes, D. N., Brambilla, E., Fernandez-Cuesta, L. & Thomas, R. K., Dec 1 2018, In : Nature communications. 9, 1, 1048.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Large Cell Carcinoma
Neuroendocrine Tumors
lungs
Tumors
10 Citations (Scopus)

Isolation and Identification of the Follicular Microbiome: Implications for Acne Research

Hall, J. B., Cong, Z., Imamura, Y., Kidd, B. A., Dudley, J. T., Thiboutot, D. & Nelson, A., Sep 1 2018, In : Journal of Investigative Dermatology. 138, 9, p. 2033-2040 8 p.

Research output: Contribution to journalArticle

Microbiota
Acne Vulgaris
Skin
Propionibacterium acnes
Sampling

MVisAGe identifies concordant and discordant genomic alterations of driver genes in squamous tumors

Walter, V., Du, Y., Danilova, L., Hayward, M. C. & Hayes, D. N., Jun 15 2018, In : Cancer Research. 78, 12, p. 3375-3385 11 p.

Research output: Contribution to journalArticle

Oncogenes
Gene Expression
DNA Copy Number Variations
Genes
Neoplasms
4 Citations (Scopus)
Long Noncoding RNA
Untranslated RNA
MicroRNAs
Liver Diseases
Hepatocellular Carcinoma
2 Citations (Scopus)

Paired Box 5 (PAX5) Expression in Poorly Differentiated Neuroendocrine Carcinoma of the Gastrointestinal and Pancreatobiliary Tract: Diagnostic and Potentially Therapeutic Implications

Ainechi, S., Mann, S. A., Lin, J., Patil, D., Sheehan, C. E., Yang, Z., Zuo, C. & Lee, H., Sep 1 2018, In : Applied Immunohistochemistry and Molecular Morphology. 26, 8, p. 545-551 7 p.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Gastrointestinal Tract
Small Cell Carcinoma
Therapeutics
Neuroendocrine Tumors
6 Citations (Scopus)

PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress

Schleicher, E. M., Galvan, A. M., Imamura, Y., Moldovan, G-L. & Nicolae, C., Jan 1 2018, In : Nucleic acids research. 46, 17, p. 8908-8916 9 p.

Research output: Contribution to journalArticle

Carcinogenesis
Cell Proliferation
HeLa Cells
Neoplasms
Clustered Regularly Interspaced Short Palindromic Repeats
1 Citation (Scopus)

Plk2 Loss Commonly Occurs in Colorectal Carcinomas but not Adenomas: Relationship to mTOR Signaling

Matthew, E. M., Yang, Z., Peri, S., Andrake, M., Dunbrack, R., Ross, E. & El-Deiry, W. S., Mar 1 2018, In : Neoplasia (United States). 20, 3, p. 244-255 12 p.

Research output: Contribution to journalArticle

Adenoma
Colorectal Neoplasms
S 6
Adenocarcinoma
Neoplasms
5 Citations (Scopus)

Proper conditional analysis in the presence of missing data: Application to large scale meta-analysis of tobacco use phenotypes

Jiang, Y., Chen, S., McGuire, D., Chen, F., Liu, M., Iacono, W. G., Hewitt, J. K., Hokanson, J. E., Krauter, K., Laakso, M., Li, K. W., Lutz, S. M., McGue, M., Pandit, A., Zajac, G. J. M., Boehnke, M., Abecasis, G. R., Vrieze, S. I., Zhan, X., Jiang, B. & 1 others, Liu, D., Jul 1 2018, In : PLoS genetics. 14, 7, e1007452.

Research output: Contribution to journalArticle

tobacco use
meta-analysis
Tobacco Use
tobacco
Meta-Analysis
4 Citations (Scopus)

Rare loss of function variants in candidate genes and risk of colorectal cancer

NHLBI GO Exome Sequencing Project, Pulmonary Arterial Hypertension (PAH), Severe Asthma Research Program (SARP), Women’s Health Initiative (WHI), Anthropometry Project Team, Blood Count/Hematology Project Team, Blood Pressure Project Team, Data Flow Working Group, Early MI Project Team, ELSI Working Group, Executive Committee, Family Study Project Team, Lipids Project Team, Lung Project Team, Personal Genomics Project Team, Phenotype and Harmonization Working Group, Population Genetics and Statistical Analysis Working Group, Publications and Presentations Working Group, Quantitative Analysis Ad Hoc Task Group, Sequencing and Genotyping Working Group & 15 others, Steering Committee, Stroke Project Team, Structural Variation Working Group, Subclinical/Quantitative Project Team, Acute Lung Injury (ALI), Atherosclerosis Risk in Communities (ARIC), Cardiovascular Health Study (CHS), Chronic Obstructive Pulmonary Disease (COPDGene), Coronary Artery Risk Development in Young Adults (CARDIA), Cystic Fibrosis (CF), Early Pseudomonas Infection Control (EPIC), Framingham Heart Study (FHS), Jackson Heart Study (JHS), Lung Health Study (LHS) & Multi-Ethnic Study of Atherosclerosis (MESA), Oct 1 2018, In : Human genetics. 137, 10, p. 795-806 12 p.

Research output: Contribution to journalArticle

Polyps
Colorectal Neoplasms
Genes
Penetrance
Genetic Testing
1 Citation (Scopus)

Repository corticotrophin injection exerts direct acute effects on human B cell gene expression distinct from the actions of glucocorticoids

Benko, A. L., McAloose, C. A., Becker, P. M., Wright, D., Sunyer, T., Imamura, Y., Olsen, N. & Kovacs, W., Apr 1 2018, In : Clinical and Experimental Immunology. 192, 1, p. 68-81 14 p.

Research output: Contribution to journalArticle

Adrenocorticotropic Hormone
Glucocorticoids
B-Lymphocytes
Gene Expression
Messenger RNA
14 Citations (Scopus)

Spatiotemporal transcriptomic divergence across human and macaque brain development

Zhu, Y., Sousa, A. M. M., Gao, T., Skarica, M., Li, M., Santpere, G., Esteller-Cucala, P., Juan, D., Ferrández-Peral, L., Gulden, F. O., Yang, M., Miller, D. J., Marques-Bonet, T., Imamura, Y., Zhao, H. & Sestan, N., Dec 14 2018, In : Science. 362, 6420, 1267.

Research output: Contribution to journalArticle

Macaca
Brain
Human Development
Prefrontal Cortex
Macaca mulatta
28 Citations (Scopus)

The 3D Genome Browser: A web-based browser for visualizing 3D genome organization and long-range chromatin interactions

Wang, Y., Song, F., Zhang, B., Zhang, L., Xu, J., Kuang, D., Li, D., Choudhary, M. N. K., Li, Y., Hu, M., Hardison, R., Wang, T. & Yue, F., Oct 4 2018, In : Genome biology. 19, 1, 151.

Research output: Contribution to journalArticle

Web Browser
Chromatin
chromatin
genome
Genome
1 Citation (Scopus)

The 7q11.23 Protein DNAJC30 Interacts with ATP Synthase and Links Mitochondria to Brain Development

Tebbenkamp, A. T. N., Varela, L., Choi, J., Paredes, M. I., Giani, A. M., Song, J. E., Sestan-Pesa, M., Franjic, D., Sousa, A. M. M., Liu, Z. W., Li, M., Bichsel, C., Koch, M., Szigeti-Buck, K., Liu, F., Li, Z., Imamura, Y., Paspalas, C. D., Mineur, Y. S., Prontera, P. & 5 others, Merla, G., Picciotto, M. R., Arnsten, A. F. T., Horvath, T. L. & Sestan, N., Nov 1 2018, In : Cell. 175, 4, p. 1088-1104.e23

Research output: Contribution to journalArticle

Mitochondrial Proton-Translocating ATPases
Williams Syndrome
Mitochondria
Machinery
Brain
4 Citations (Scopus)

The DGCR5 long noncoding RNA may regulate expression of several schizophrenia-related genes

Meng, Q., Wang, K., Brunetti, T., Xia, Y., Jiao, C., Dai, R., Fitzgerald, D., Thomas, A., Jay, L., Eckart, H., Grennan, K., Imamura, Y., Li, M., Sestan, N., White, K. P., Chen, C. & Liu, C., Dec 19 2018, In : Science Translational Medicine. 10, 472, eaat6912.

Research output: Contribution to journalArticle

Long Noncoding RNA
Schizophrenia
Genes
RNA Sequence Analysis
Induced Pluripotent Stem Cells

The expression of TTF1, CDX2 and ISL1 in 74 poorly differentiated neuroendocrine carcinomas

Lee, H., Fu, Z., Koo, B. H., Sheehan, C. E., Young, G. Q., Lin, J., Patil, D. T. & Yang, Z., Dec 1 2018, In : Annals of Diagnostic Pathology. 37, p. 30-34 5 p.

Research output: Contribution to journalArticle

Neuroendocrine Carcinoma
Small Cell Carcinoma
Staining and Labeling
Lung
Students
18 Citations (Scopus)

The Integrated Genomic Landscape of Thymic Epithelial Tumors

The Cancer Genome Atlas Network, Feb 12 2018, In : Cancer Cell. 33, 2, p. 244-258.e10

Research output: Contribution to journalArticle

Thymoma
Myasthenia Gravis
Autoantigens
Aneuploidy
Mutation

Transdifferentiation of Human Circulating Monocytes Into Neuronal-Like Cells in 20 Days and Without Reprograming

Bellon, A., Wegener, A., Lescallette, A. R., Valente, M., Yang, S. K., Gardette, R., Matricon, J., Mouaffak, F., Watts, P., Vimeux, L., Yun, J., Imamura, Y., Clawson, G., Blandin, E., Chaumette, B., Jay, T. M., Krebs, M. O., Feuillet, V. & Hosmalin, A., Sep 19 2018, In : Frontiers in Molecular Neuroscience. 11, 323.

Research output: Contribution to journalArticle

Monocytes
Neurons
Neuronal Plasticity
Electrophysiology
Dopamine Receptors
1 Citation (Scopus)

Tumor molecular profiling for an individualized approach to the treatment of hepatocellular carcinoma: A patient case study

Posadas, K., Ankola, A., Yang, Z. & Yee, N. S-S., Jun 1 2018, In : Biomedicines. 6, 2, 46.

Research output: Contribution to journalArticle

Tumors
Hepatocellular Carcinoma
oxaliplatin
Chemotherapy
Catenins
13 Citations (Scopus)

Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism

The New York Genome Center ALS Consortium, Jul 13 2018, In : eLife. 7, e37754.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Heterogeneous-Nuclear Ribonucleoprotein Group F-H
Brain
RNA-Binding Proteins
Genes
1 Citation (Scopus)

WDR68 is essential for the transcriptional activation of the PRC1-AUTS2 complex and neuronal differentiation of mouse embryonic stem cells

Wang, Q., Geng, Z., Gong, Y., Warren, K., Zheng, H., Imamura, Y. & Gao, Z., Dec 1 2018, In : Stem Cell Research. 33, p. 206-214 9 p.

Research output: Contribution to journalArticle

Open Access
Autistic Disorder
Transcriptional Activation
Polycomb Repressive Complex 1
Genes
Mouse Embryonic Stem Cells
2017
12 Citations (Scopus)

A comprehensive NGS data analysis of differentially regulated miRNAs, piRNAs, lncRNas and sn/snoRNAs in triple negative breast cancer

Koduru, S., Tiwari, A. K., Leberfinger, A., Hazard, S. W., Imamura, Y., Mahajan, M. & Ravnic, D., Jan 1 2017, In : Journal of Cancer. 8, 4, p. 578-596 19 p.

Research output: Contribution to journalArticle

Small Nucleolar RNA
Long Noncoding RNA
Triple Negative Breast Neoplasms
Small Untranslated RNA
MicroRNAs
2 Citations (Scopus)

Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident

Goldenberg, D., Russo, M., Houser, K., Crist, H., Derr, J. B., Walter, V., Warrick, J., Sheldon, K. E., Broach, J. & Bann, D. V., Jul 1 2017, In : Laryngoscope. 127, p. S1-S9

Research output: Contribution to journalArticle

Radioactive Hazard Release
Thyroid Neoplasms
Islands
Gene Fusion
Radiation-Induced Neoplasms
5 Citations (Scopus)

Association of frequent genetic variants in platelet activation pathway genes with large-vessel ischemic stroke in Polish population

Postula, M., Janicki, P., Milanowski, L., Pordzik, J., Eyileten, C., Karlinski, M., Wylezol, P., Solarska, M., Czlonkowka, A., Kurkowska-Jastrzebka, I., Sugino, S., Imamura, Y. & Mirowska-Guzel, D., Jan 2 2017, In : Platelets. 28, 1, p. 66-73 8 p.

Research output: Contribution to journalArticle

Platelet Activation
Stroke
Gene Frequency
Blood Platelets
Population
3 Citations (Scopus)

Autologous reconstitution of human cancer and immune system in vivo

Fu, J., Sen, R., Masica, D. L., Karchin, R., Pardoll, D., Walter, V., Hayes, D. N., Chung, C. H. & Kim, Y. J., Jan 1 2017, In : Oncotarget. 8, 2, p. 2053-2068 16 p.

Research output: Contribution to journalArticle

Immune System
Tumor Microenvironment
Neoplasms
Human Trafficking
Tumor-Infiltrating Lymphocytes
3 Citations (Scopus)

Circulating cholesterol levels may link to the factors influencing Parkinson's Risk

Zhang, L., Wang, X., Wang, M., Sterling, N. W., Du, G., Lewis, M., Yao, T., Mailman, R., Li, R. & Huang, X., Sep 27 2017, In : Frontiers in Neurology. 8, SEP, 501.

Research output: Contribution to journalArticle

Parkinson Disease
Cholesterol
LDL Cholesterol
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Propensity Score
8 Citations (Scopus)

Clonal evolution in paired endometrial intraepithelial neoplasia/atypical hyperplasia and endometrioid adenocarcinoma

Russo, M., Broach, J., Sheldon, K., Houser, K. R., Liu, D., Kesterson, J., Phaeton, R., Hossler, C., Hempel, N., Baker, M., Newell, J., Zaino, R. & Warrick, J., Sep 1 2017, In : Human Pathology. 67, p. 69-77 9 p.

Research output: Contribution to journalArticle

Clonal Evolution
Endometrioid Carcinoma
Endometrial Hyperplasia
Hyperplasia
Endometrial Neoplasms
138 Citations (Scopus)

Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

Fishbein, L., Leshchiner, I., Walter, V., Danilova, L., Robertson, A. G., Johnson, A. R., Lichtenberg, T. M., Murray, B. A., Ghayee, H. K., Else, T., Ling, S., Jefferys, S. R., de Cubas, A. A., Wenz, B., Korpershoek, E., Amelio, A. L., Makowski, L., Rathmell, W. K., Gimenez-Roqueplo, A. P., Giordano, T. J. & 187 others, Asa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Arachchi, H., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Lin, P., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Riester, A., Roach, J., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J. J., Zhang, W., Zhu, J., Zinzindohoué, F. & Zmuda, E., Feb 13 2017, In : Cancer Cell. 31, 2, p. 181-193 13 p.

Research output: Contribution to journalArticle

Paraganglioma
Pheochromocytoma
Gene Fusion
Genes
Precision Medicine
17 Citations (Scopus)

Control of species-dependent cortico-motoneuronal connections underlying manual dexterity

Gu, Z., Kalamboglas, J., Yoshioka, S., Han, W., Li, Z., Imamura, Y., Pochareddy, S., Li, Z., Liu, F., Xu, X., Wijeratne, S., Ueno, M., Blatz, E., Salomone, J., Kumanogoh, A., Rasin, M. R., Gebelein, B., Weirauch, M. T., Sestan, N., Martin, J. H. & 1 others, Yoshida, Y., Jul 28 2017, In : Science. 357, 6349, p. 400-404 5 p.

Research output: Contribution to journalArticle

Primates
Motor Cortex
2 Citations (Scopus)

Corrigendum: The 4D nucleome project (Nature (2017) 549 (219-226) DOI: 10.1038/nature23884)

4D Nucleome Network, Dec 14 2017, In : Nature. 552, 7684, 1 p.

Research output: Contribution to journalComment/debate

Open Access
health
director
funding
Factor VIII
Assays
Screening
Blood Coagulation Factors
Thromboplastin

Endobronchial Sarcoidosis

Scrobola, J. F., McClune, J. R., Harriott, A. J., Yang, Z. & Gilbert, C. R., Jan 1 2017, In : Journal of Bronchology and Interventional Pulmonology. 24, 4, p. 303-306 4 p.

Research output: Contribution to journalArticle

Sarcoidosis
5 Citations (Scopus)

Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection

Serfass, J. M., Takahashi, Y., Zhou, Z., Imamura, Y., Liu, Y., Tsotakos, N., Young, M. M., Tang, Z., Yang, L., Xavier, J., Chroneos, Z. & Wang, H-G., Jun 16 2017, In : Journal of Biological Chemistry. 292, 24, p. 10097-10111 15 p.

Research output: Contribution to journalArticle

Endosomes
Influenza A virus
Autophagy
Virus Diseases
Viruses
Brain-Computer Interfaces
Amyotrophic Lateral Sclerosis
Evoked Potentials
Neurodegenerative Diseases
Alleles
25 Citations (Scopus)

Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment

Gezgin, G., Dogrusöz, M., van Essen, T. H., Kroes, W. G. M., Luyten, G. P. M., van der Velden, P. A., Walter, V., Verdijk, R. M., van Hall, T., van der Burg, S. H. & Jager, M. J., Jul 1 2017, In : Cancer Immunology, Immunotherapy. 66, 7, p. 903-912 10 p.

Research output: Contribution to journalArticle

Molecular Evolution
T-Lymphocytes
Chromosomes, Human, Pair 3
Chromosomes
Macrophages

Genome-wide profiling of differentially spliced mRNAs in human fetal cortical tissue exposed to alcohol

Imamura, Y., Mohammad, S., Son, A. I., Morizono, H., Basha, A., Salzberg, A. C., Torii, M. & Hashimoto-Torii, K., Aug 1 2017, In : Alcohol. 62, p. 1-9 9 p.

Research output: Contribution to journalArticle

alcohol consumption
Protein Isoforms
Fetus
Ethanol
Genes

HiCComp: Multiple-level comparative analysis of Hi-C data by triplet network

Zhang, Y., Zhang, B., Zheng, W. J., Tang, J. & Yue, F., Dec 15 2017, Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017. Yoo, I., Zheng, J. H., Gong, Y., Hu, X. T., Shyu, C-R., Bromberg, Y., Gao, J. & Korkin, D. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 92-96 5 p. (Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017; vol. 2017-January).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Genes
Tissue
Neural networks
Transcription factors
Binding sites
29 Citations (Scopus)

HiCRep: assessing the reproducibility of Hi-C data using a stratum-adjusted correlation coefficient

Yang, T., Zhang, F., Yardımci, G. G., Song, F., Hardison, R. C., Noble, W. S., Yue, F. & Li, Q., Nov 2017, In : Genome research. 27, 11, p. 1939-1949 11 p.

Research output: Contribution to journalArticle

Cell Lineage
Quality Control
Chromatin
Genome
Technology
5 Citations (Scopus)
Tobacco
Mouth Neoplasms
Biomarkers
carcinogens
Early Detection of Cancer
8 Citations (Scopus)

Identification of a rare LAMB4 variant associated with familial diverticulitis through exome sequencing

Coble, J. L., Yue, F., Salameh, T. J., Harris, L. R., Deiling, S., Ruggiero, F. M., Eshelman, M. A., Yochum, G. S., Koltun, W. A., Gerhard, G. S. & Broach, J. R., Aug 15 2017, In : Human Molecular Genetics. 26, 16, p. 3212-3220 9 p., ddx204.

Research output: Contribution to journalArticle

Exome
Diverticulitis
Enteric Nervous System
Laminin
Genes
19 Citations (Scopus)

Immunohistochemical Characterization of the Origins of Metastatic Well-differentiated Neuroendocrine Tumors to the Liver

Yang, Z., Klimstra, D. S., Hruban, R. H. & Tang, L. H., Jan 1 2017, In : American Journal of Surgical Pathology. 41, 7, p. 915-922 8 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Liver
Bile Ducts
Rectum
Lung
74 Citations (Scopus)

Integrated Molecular Characterization of Uterine Carcinosarcoma

Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S. & 130 others, Baylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R. G. W., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J. J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In : Cancer Cell. 31, 3, p. 411-423 13 p.

Research output: Contribution to journalArticle

Carcinosarcoma
Epithelial-Mesenchymal Transition
Epigenomics
Proteomics
Mutation