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Research Output 1975 2019

1992
20 Citations (Scopus)

The 45- and 104-kDa forms of phosphatidate phosphatase from Saccharomyces cerevisiae are regulated differentially by phosphorylation via cAMP-dependent protein kinase

Quinlan, J. J., Nickels, J. T., Wu, W. I., Lin, Y. P., Broach, J. & Carman, G. M., Jan 1 1992, In : Journal of Biological Chemistry. 267, 25, p. 18013-18020 8 p.

Research output: Contribution to journalArticle

Phosphatidate Phosphatase
Phosphorylation
Cyclic AMP-Dependent Protein Kinases
Yeast
Saccharomyces cerevisiae
1991
208 Citations (Scopus)

Cloning Genes by Complementation in Yeast

Rose, M. D. & Broach, J., Jan 1 1991, In : Methods in Enzymology. 194, C, p. 195-230 36 p.

Research output: Contribution to journalArticle

Cloning
Yeast
Organism Cloning
Genes
Yeasts
131 Citations (Scopus)

Evidence suggesting that the ARS elements associated with silencers of the yeast mating-type locus HML do not function as chromosomal DNA replication origins

Dubey, D. D., Davis, L. R., Greenfeder, S. A., Ong, L. Y., Zhu, J., Broach, J., Newlon, C. S. & Huberman, J. A., Jan 1 1991, In : Molecular and cellular biology. 11, 10, p. 5346-5355 10 p.

Research output: Contribution to journalArticle

Replication Origin
Telomere
DNA Replication
Yeasts
Plasmids
66 Citations (Scopus)

Mutations in the HML E silencer of Saccharomyces cerevisiae yield metastable inheritance of transcriptional repression

Mahoney, D. J., Marquardt, R., Shei, G. J., Rose, A. B. & Broach, J., Jan 1 1991, In : Genes and Development. 5, 4, p. 605-615 11 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae
Mutation
Genes
DNA-Binding Proteins
DNA Replication
163 Citations (Scopus)

RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway

Broach, J., Jan 1 1991, In : Trends in Genetics. 7, 1, p. 28-33 6 p.

Research output: Contribution to journalArticle

ras Proteins
Saccharomycetales
Saccharomyces cerevisiae
Signal Transduction
Cell Cycle
39 Citations (Scopus)

Ras-regulated signaling processes in Saccharomyces cerevisiae

Broach, J., Jan 1 1991, In : Current Opinion in Genetics and Development. 1, 3, p. 370-377 8 p.

Research output: Contribution to journalArticle

ras Proteins
Guanine Nucleotides
GTP Phosphohydrolases
Post Translational Protein Processing
Saccharomyces cerevisiae
130 Citations (Scopus)

The CDC25 Protein of Saccharomyces cerevisiae Promotes Exchange of Guanine Nucleotides Bound to Ras

Jones, S., Vignais, M. L. & Broach, J., Jan 1 1991, In : Molecular and Cellular Biology. 11, 5, p. 2641-2646 6 p.

Research output: Contribution to journalArticle

ras-GRF1
Saccharomyces cerevisiae Proteins
Guanine Nucleotides
Galactosidases
Guanosine Triphosphate
101 Citations (Scopus)

The Saccharomyces cerevisiae YAK1 gene encodes a protein kinase that is induced by arrest early in the cell cycle

Garrett, S., Menold, M. M. & Broach, J., Jan 1 1991, In : Molecular and Cellular Biology. 11, 8, p. 4045-4052 8 p.

Research output: Contribution to journalArticle

Protein Kinases
Saccharomyces cerevisiae
Cell Cycle
Adenosine Monophosphate
Genes
1990
28 Citations (Scopus)

Acylation and prenylation of proteins

Deschenes, R. J., Resh, M. D. & Broach, J., Jan 1 1990, In : Current Opinion in Cell Biology. 2, 6, p. 1108-1113 6 p.

Research output: Contribution to journalArticle

Myristic Acids
Butadienes
Protein Prenylation
Palmitic Acids
Acylation
8 Citations (Scopus)

Cell fates in C. elegans: In medias ras

Greenwald, I. & Broach, J., Dec 21 1990, In : Cell. 63, 6, p. 1113-1116 4 p.

Research output: Contribution to journalShort survey

Caenorhabditis
Biological Models
ras Genes
Saccharomyces cerevisiae
Cell Differentiation
88 Citations (Scopus)

Propagation and expression of cloned genes in yeast: 2-μm circle-based vectors

Rose, A. B. & Broach, J., Jan 1 1990, In : Methods in enzymology. 185, C, p. 234-279 46 p.

Research output: Contribution to journalArticle

Yeast
Genes
179 Citations (Scopus)

SRV2, a gene required for RAS activation of adenylate cyclase in yeast

Fedor-Chaiken, M., Deschenes, R. J. & Broach, J., Apr 20 1990, In : Cell. 61, 2, p. 329-340 12 p.

Research output: Contribution to journalArticle

Adenylyl Cyclases
Yeast
Genes
Yeasts
Chemical activation
158 Citations (Scopus)

The function of ras genes in: Saccharomyces cerevisiae

Broach, J. & Deschenes, R. J., Jan 1 1990, In : Advances in Cancer Research. 54, C, p. 79-139 61 p.

Research output: Contribution to journalArticle

ras Genes
Saccharomyces cerevisiae
Proteins
Adenylyl Cyclases
Yeasts
1989
31 Citations (Scopus)

A general screen for mutant of Saccharomyces cerevisiae deficient in tRNA biosynthesis.

van Zyl, W. H., Wills, N. & Broach, J., Sep 1989, In : Genetics. 123, 1, p. 55-68 14 p.

Research output: Contribution to journalArticle

Transfer RNA
Saccharomyces cerevisiae
Temperature
Introns
Genes
63 Citations (Scopus)

Deoxyribonucleic acid plasmids in yeasts

Volkert, F. C., Wilson, D. W. & Broach, J., Jan 1 1989, In : Microbiological Reviews. 53, 3, p. 299-317 19 p.

Research output: Contribution to journalReview article

Fungal Gene Expression Regulation
Fungal DNA
Genetic Vectors
Restriction Mapping
Saccharomyces
163 Citations (Scopus)
Cyclic AMP-Dependent Protein Kinases
Saccharomyces cerevisiae
Phosphotransferases
Growth
Genes
18 Citations (Scopus)

Propagation and expression of genes in yeast using 2-micron circle vectors.

Armstrong, K. A., Som, T., Volkert, F. C., Rose, A. & Broach, J., Jan 1 1989, In : Biotechnology (Reading, Mass.). 13, p. 165-192 28 p.

Research output: Contribution to journalReview article

54 Citations (Scopus)

RAS2 protein of Saccharomyces cerevisiae is methyl-esterified at its carboxyl terminus

Deschenes, R. J., Stimmel, J. B., Clarke, S., Stock, J. & Broach, J., 1989, In : Journal of Biological Chemistry. 264, 20, p. 11865-11873 9 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae Proteins
Cysteine
Esterification
ras Proteins
Proteins
78 Citations (Scopus)

The HML mating-type cassette of Saccharomyces cerevisiae is regulated by two separate but functionally equivalent silencers

Mahoney, D. J. & Broach, J., Jan 1 1989, In : Molecular and cellular biology. 9, 11, p. 4621-4630 10 p.

Research output: Contribution to journalArticle

Fungal Gene Expression Regulation
Fungal Chromosomes
Fungal RNA
Fungal Genes
Genetic Transcription
1988
88 Citations (Scopus)

Autoregulation of 2μm circle gene expression provides a model for maintenance of stable plasmid copy levels

Som, T., Armstrong, K. A., Volkert, F. C. & Broach, J., Jan 15 1988, In : Cell. 52, 1, p. 27-37 11 p.

Research output: Contribution to journalArticle

Gene expression
Plasmids
Homeostasis
Maintenance
Gene Expression
1987
43 Citations (Scopus)

A yeast plasmid partitioning protein is a karyoskeletal component

Wu, L. C. C., Fisher, P. A. & Broach, J., Jan 1 1987, In : Journal of Biological Chemistry. 262, 2, p. 883-891 9 p.

Research output: Contribution to journalArticle

Yeast
Plasmids
Yeasts
Proteins
Scleroproteins
42 Citations (Scopus)

Expression of Rous sarcoma virus transforming protein pp60v-src in Saccharomyces cerevisiae cells.

Brugge, J. S., Jarosik, G., Andersen, J., Queral-Lustig, A., Fedor-Chaiken, M. & Broach, J., Jan 1 1987, In : Molecular and Cellular Biology. 7, 6, p. 2180-2187 8 p.

Research output: Contribution to journalArticle

Rous sarcoma virus
Saccharomyces cerevisiae
Yeasts
src Genes
Proteins
64 Citations (Scopus)

Fatty acylation is important but not essential for Saccharomyces cerevisiae RAS function.

Deschenes, R. J. & Broach, J. R., Jul 1987, In : Molecular and cellular biology. 7, 7, p. 2344-2351 8 p.

Research output: Contribution to journalArticle

Acylation
Saccharomyces cerevisiae
Fungal Proteins
Terminator Codon
Palmitates
84 Citations (Scopus)

Functional domains of SIR4, a gene required for position effect regulation in Saccharomyces cerevisiae.

Marshall, M., Mahoney, D., Rose, A., Hicks, J. B. & Broach, J., Jan 1 1987, In : Molecular and cellular biology. 7, 12, p. 4441-4452 12 p.

Research output: Contribution to journalArticle

Gene Order
Saccharomyces cerevisiae
Genes
Chromosomes
Gene Expression
2 Citations (Scopus)

MECHANISM OF PROPAGATION OF THE YEAST 2- mu m CIRCLE PLASMID.

Volkert, F. C. & Broach, J., 1987, Unknown Host Publication Title. Stewart, G. G., Russell, I., Klein, R. D. & Hiebsch, R. R. (eds.). CRC Press Inc, Vol. 2. p. 145-170 26 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yeast
DNA
1986
83 Citations (Scopus)

Identification of the crossover site during FLP-mediated recombination in the Saccharomyces cerevisiae plasmid 2 microns circle.

McLeod, M., Craft, S. & Broach, J., Jan 1 1986, In : Molecular and cellular biology. 6, 10, p. 3357-3367 11 p.

Research output: Contribution to journalArticle

Genetic Recombination
Saccharomyces cerevisiae
Plasmids
Gene Conversion
Base Pairing
26 Citations (Scopus)

Interaction of the FLP recombinase of the Saccharomyces cerevisiae 2 micron plasmid with mutated target sequences.

Andrews, B. J., McLeod, M., Broach, J. & Sadowski, P. D., Jan 1 1986, In : Molecular and cellular biology. 6, 7, p. 2482-2489 8 p.

Research output: Contribution to journalArticle

Genetic Recombination
Saccharomyces cerevisiae
Plasmids
Base Pairing
Mutation
8 Citations (Scopus)

New approaches to a genetic analysis of mitosis

Broach, J., Jan 17 1986, In : Cell. 44, 1, p. 3-4 2 p.

Research output: Contribution to journalShort survey

Genetic Nondisjunction
Fungal Genes
Genetic Suppression
Type II DNA Topoisomerase
Fungal Proteins
136 Citations (Scopus)

Site-specific recombination promotes plasmid amplification in yeast

Volkert, F. C. & Broach, J., Aug 15 1986, In : Cell. 46, 4, p. 541-550 10 p.

Research output: Contribution to journalArticle

Yeast
Genetic Recombination
Amplification
Plasmids
Yeasts
6 Citations (Scopus)

Survival strategies of the yeast plasmid two-micron circle.

Volkert, F. C., Wu, L. C., Fisher, P. A. & Broach, J., Dec 1 1986, In : Basic life sciences. 40, p. 375-396 22 p.

Research output: Contribution to journalArticle

Plasmids
Yeasts
Cell Division
Centromere
Mitosis
1985
12 Citations (Scopus)

ATP-dependent specific binding of Tn3 transposase to Tn3 inverted repeats

Wishart, W. L., Broach, J. & Ohtsubo, E., Dec 1 1985, In : Nature. 314, 6011, p. 556-558 3 p.

Research output: Contribution to journalArticle

Transposases
Adenosine Triphosphate
DNA
Proteins
Heparin
158 Citations (Scopus)

Functional homology of mammalian and yeast RAS genes

Kataoka, T., Powers, S., Cameron, S., Fasano, O., Goldfarb, M., Broach, J. & Wigler, M., Jan 1 1985, In : Cell. 40, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

Yeast
Genes
Yeasts
Galactose
Haploidy
682 Citations (Scopus)

In yeast, RAS proteins are controlling elements of adenylate cyclase

Toda, T., Uno, I., Ishikawa, T., Powers, S., Kataoka, T., Broek, D., Cameron, S., Broach, J., Matsumoto, K. & Wigler, M., Jan 1 1985, In : Cell. 40, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Adenylyl Cyclases
Yeast
Yeasts
Proteins
Membranes
44 Citations (Scopus)

Properties of REP3: A cis-acting locus required for stable propagation of the Saccharomyces cerevisiae plasmid 2μm circle

Jayaram, M., Sutton, A. & Broach, J., Jan 1 1985, In : Molecular and Cellular Biology. 5, 9, p. 2466-2475 10 p.

Research output: Contribution to journalArticle

Fungal Genes
Genetic Transformation
Circular DNA
Replicon
Regulator Genes
30 Citations (Scopus)

Signals for transcription initiation and termination in the Saccharomyces cerevisiae plasmid 2μm circle

Sutton, A. & Broach, J., Jan 1 1985, In : Molecular and Cellular Biology. 5, 10, p. 2770-2780 11 p.

Research output: Contribution to journalArticle

Fungal RNA
Post Transcriptional RNA Processing
RNA Caps
Fungal DNA
Fungal Genes
1984
19 Citations (Scopus)

Components of the site-specific recombination system encoded by the yeast plasmid 2-micron circle

McLeod, M., Volkert, F. & Broach, J., Jan 1 1984, In : Cold Spring Harbor Symposia on Quantitative Biology. VOL. 49, p. 779-787 9 p.

Research output: Contribution to journalArticle

site-specific recombination
genetic recombination
chromosome mapping
binding sites
plasmids
223 Citations (Scopus)

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins

Powers, S., Kataoka, T., Fasano, O., Goldfarb, M., Strathem, J., Broach, J. & Wigler, M., Jan 1 1984, In : Cell. 36, 3, p. 607-612 6 p.

Research output: Contribution to journalArticle

Saccharomyces cerevisiae Proteins
ras Proteins
Genes
Fungal Proteins
Yeast
259 Citations (Scopus)

Genetic analysis of yeast RAS1 and RAS2 genes

Kataoka, T., Powers, S., McGill, C., Fasano, O., Strathern, J., Broach, J. & Wigler, M., Jan 1 1984, In : Cell. 37, 2, p. 437-445 9 p.

Research output: Contribution to journalArticle

ras Genes
Yeast
Genes
Yeasts
Diploidy
75 Citations (Scopus)

Identification of sites required for repression of a silent mating type locus in yeast

Feldman, J. B., Hicks, J. B. & Broach, J., Oct 5 1984, In : Journal of Molecular Biology. 178, 4, p. 815-834 20 p.

Research output: Contribution to journalArticle

Yeasts
Plasmids
Mars
Saccharomyces
DNA Replication
10 Citations (Scopus)

Structure of the SAD mutation and the location of control sites at silent mating type genes in Saccharomyces cerevisiae

Hicks, J., Strathern, J., Klar, A., Ismail, S. & Broach, J., Jan 1 1984, In : Molecular and cellular biology. 4, 7, p. 1278-1285 8 p.

Research output: Contribution to journalArticle

Fungal Mating Type Genes
Fungal Genes
Genetic Crosses
Lethal Genes
Species Specificity
1983
101 Citations (Scopus)

[21] Construction of High Copy Yeast Vectors Using 2-μm Circle Sequences

Broach, J., Jan 1 1983, In : Methods in enzymology. 101, C, p. 307-325 19 p.

Research output: Contribution to journalArticle

Fungal DNA
Genetic engineering
Genetic Vectors
DNA Restriction Enzymes
Yeast
98 Citations (Scopus)

The yeast plasmid 2μ circle encodes components required for its high copy propagation

Jayaram, M., Li, Y. Y. & Broach, J., Jan 1 1983, In : Cell. 34, 1, p. 95-104 10 p.

Research output: Contribution to journalArticle

Yeast
Plasmids
Yeasts
Replication Origin
Nucleic Acid Repetitive Sequences
9 Citations (Scopus)
Genetic Recombination
Yeasts
Plasmids
Genome
1982
59 Citations (Scopus)

Genetic properties of chromosomally integrated 2μ plasmid DNA in yeast

Falco, S. C., Li, Y., Broach, J. & Botstein, D., Jan 1 1982, In : Cell. 29, 2, p. 573-584 12 p.

Research output: Contribution to journalArticle

Chromosomes
Yeast
Plasmids
Yeasts
DNA
241 Citations (Scopus)

Localization and sequence analysis of yeast origins of DNA replication

Broach, J., Li, Y. Y., Feldman, J., Jayaram, M., Abraham, J., Nasmyth, K. A. & Hicks, J. B., Dec 1 1982, In : Cold Spring Harbor Symposia on Quantitative Biology. 47, 2, p. 1165-1173 9 p.

Research output: Contribution to journalArticle

DNA replication
Saccharomyces cerevisiae
plasmids
sequence analysis
transcription (genetics)
153 Citations (Scopus)

Recombination within the yeast plasmid 2μ circle is site-specific

Broach, J., Guarascio, V. R. & Jayaram, M., Jan 1 1982, In : Cell. 29, 1, p. 227-234 8 p.

Research output: Contribution to journalArticle

Yeast
Genetic Recombination
Plasmids
Genes
Yeasts
35 Citations (Scopus)

Sites required for position-effect regulation of mating-type information in yeast

Abraham, J., Feldman, J., Nasmyth, K. A., Strathern, J. N., Klar, A. J., Broach, J. & Hicks, J. B., Dec 1 1982, In : Cold Spring Harbor Symposia on Quantitative Biology. 47, 2, p. 989-998 10 p.

Research output: Contribution to journalArticle

Genetic Crosses
position effect (genetics)
Superhelical DNA
chromosome elimination
genetic recombination
47 Citations (Scopus)

The yeast plasmid 2μ circle

Broach, J., Jan 1 1982, In : Cell. 28, 2, p. 203-204 2 p.

Research output: Contribution to journalArticle

Circular DNA
DNA Replication
Genetic Recombination
Saccharomyces cerevisiae
Cell Cycle
1981
20 Citations (Scopus)

Correspondence of yeast UAA suppressors to cloned tRNAUCA Ser genes

Broach, J., Friedman, L. & Sherman, F., Aug 15 1981, In : Journal of Molecular Biology. 150, 3, p. 375-387 13 p.

Research output: Contribution to journalArticle

Yeasts
Plasmids
Genes
Alleles
DNA
102 Citations (Scopus)

Regulation of transcription in expressed and unexpressed mating type cassettes of yeast

Klar, A. J. S., Strathern, J. N., Broach, J. & Hicks, J. B., Dec 1 1981, In : Nature. 289, 5795, p. 239-244 6 p.

Research output: Contribution to journalArticle

Saccharomyces
DNA Transposable Elements
Yeasts
Genes