• 25299 Citations
  • 77 h-Index
1969 …2019

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Article
1996

Overexpression of HER2 modulates bcl-2, Bcl-X(L) and tamoxifen induced apoptosis in human MCP-7 breast cancer cells

Kumar, R., Mandal, M., Lipton, A., Harvey, H. & Thompson, C. B., Jul 1 1996, In : Clinical Cancer Research. 2, 7, p. 1215-1219 5 p.

Research output: Contribution to journalArticle

126 Scopus citations

Pamidronate (Aredia).

Lipton, A., Sep 1996, In : British journal of clinical practice. Supplement. 87, p. 2; discussion 13-14

Research output: Contribution to journalArticle

Pamidronate (Aredia) and zoledronate: update on clinical results. Introduction.

Lipton, A. & Delmas, P. D., Sep 1996, In : British journal of clinical practice. Supplement. 87, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Phase I trial of recombinant platelet factor 4 (rPF4) in patients with advanced colorectal carcinoma

Belman, N., Bonnem, E. M., Harvey, H. A. & Lipton, A., Jan 1 1996, In : Investigational New Drugs. 14, 4, p. 387-389 3 p.

Research output: Contribution to journalArticle

24 Scopus citations

Protein tyrosine kinase activity in breast cancer and its relation to prognostic indicators

Kopreski, M. S., Witters, L., Brennan, W. A., Buckwalter, E. A., Chinchilli, V., Demers, L. & Lipton, A., Sep 1 1996, In : Anticancer Research. 16, 5 B, p. 3037-3041 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Serial serum c-erbB-2 levels in patients with breast carcinoma

Volas, G. H., Leitzel, K., Teramoto, Y., Grossberg, H., Demers, L. & Lipton, A., Jul 15 1996, In : Cancer. 78, 2, p. 267-272 6 p.

Research output: Contribution to journalArticle

64 Scopus citations

The impact of 2D versus 3D quantitation of tumor bulk determination on current methods of assessing response to treatment

Hopper, K. D., Kasales, C. J., Eggli, K. D., TenHave, T. R., Belman, N. M., Potok, P. S., Van Slyke, M. A., Olt, G. J., Close, P., Lipton, A., Harvey, H. A. & Hartzel, J. S., Nov 1 1996, In : Journal of Computer Assisted Tomography. 20, 6, p. 930-937 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

The role of bisphosphonates in the treatment of bone metastases - The U.S. experience

Harvey, H. & Lipton, A., May 1996, In : Supportive Care in Cancer. 4, 3, p. 213-217 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Zoledronate in the treatment of osteolytic bone metastases

Lipton, A., Dec 1 1996, In : British Journal of Clinical Practice. SUPPL. 87, 1 p.

Research output: Contribution to journalArticle

7 Scopus citations
1995

Aromatase inhibitor development for treatment of breast cancer

Masamura, S., Adlercreutz, H., Harvey, H., Lipton, A., Demers, L., Santen, R. J. & Santner, S. J., Jan 1 1995, In : Breast Cancer Research and Treatment. 33, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Biochemical markers of bone turnover in patients with metastatic bone disease

Demers, L., Costa, L., Chinchilli, V., Gaydos, L., Curley, E. & Lipton, A., 1995, In : Clinical Chemistry. 41, 10, p. 1489-1494 6 p.

Research output: Contribution to journalArticle

131 Scopus citations

Bone markers in osteoporosis and malignancy.

Lipton, A., Costa, L. & Demers, L., Dec 1995, In : The Canadian journal of oncology. 5 Suppl 1, p. 11-15 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Calcium absorption, endogenous excretion, and endocrine changes during and after long-term bed rest

Leblanc, A., Schneider, V., Spector, E., Evans, H., Rowe, R., Lane, H., Demers, L. & Lipton, A., Apr 1995, In : Bone. 16, 4 SUPPL., p. S301-S304

Research output: Contribution to journalArticle

94 Scopus citations

Elevated serum c-erbB-2 antigen levels and decreased response to hormone therapy of breast cancer

Leitzel, K., Teramoto, Y., Konrad, K., Chinchilli, V., Volas, G., Grossberg, H., Harvey, H., Demers, L. & Lipton, A., Jan 1 1995, In : Journal of Clinical Oncology. 13, 5, p. 1129-1135 7 p.

Research output: Contribution to journalArticle

289 Scopus citations

Epidermal Growth Factor Receptor Ectodomain in the Urine of Patients with Squamous Cell Carcinoma

Witters, L. M., Curley, E. M., Kumar, R., Chinchilli, V., Harvey, J. P., Crebbin, V., Harvey, H. & Lipton, A., May 1 1995, In : Clinical Cancer Research. 1, 5, p. 551-557 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Letrozole (CGS 20267). A phase I study of a new potent oral aromatase inhibitor of breast cancer

Lipton, A., Demers, L. M., Harvey, H. A., Kambic, K. B., Grossberg, H., Brady, C., Adlercruetz, H., Trunet, P. F. & Santen, R. J., Apr 15 1995, In : Cancer. 75, 8, p. 2132-2138 7 p.

Research output: Contribution to journalArticle

97 Scopus citations
1994

Intravenous pamidronate disodium treatment of bone metastases in patients with breast cancer. A dose‐seeking study

Glover, D., Lipton, A., Keller, A., Miller, A. A., Browning, S., Fram, R. J., George, S., Zelenakas, K., Macerata, R. S. & Seaman, J. J., Dec 1 1994, In : Cancer. 74, 11, p. 2949-2955 7 p.

Research output: Contribution to journalArticle

121 Scopus citations

Pamidronate in the treatment of bone metastases: Results of 2 dose-ranging trials in patients with breast or prostate cancer

Lipton, A., Glover, D., Harvey, H., Grabelsky, S., Zelenakas, K., Macerata, R. & Seaman, J., Jan 1 1994, In : Annals of Oncology. 5, SUPPL. 7, p. 31-35 5 p.

Research output: Contribution to journalArticle

65 Scopus citations

The role of pamidronate

Lipton, A., Jan 1 1994, In : Annals of Oncology. 5, SUPPL. 7, p. 25-26 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Transforming growth factors-α and -β1 levels in plasma and effusions from patients with cancer or hematologic malignancies

Witters, L. M., Al-Mondhiry, H., Matthews, Y. L., Walker, R. P., Langton, B. C., Dasch, J. R. & Lipton, A., Jan 1 1994, In : International journal of oncology. 4, 4, p. 943-950 8 p.

Research output: Contribution to journalArticle

1993

Increased urinary excretion of pyridinium cross-links in cancer patients

Lipton, A., Demers, L., Daniloff, Y., Curley, E., Hamilton, C., Harvey, H., Witters, L., Seaman, J., Van der Giessen, R. & Seyedin, S., Jan 1 1993, In : Clinical Chemistry. 39, 4, p. 614-618 5 p.

Research output: Contribution to journalArticle

74 Scopus citations

Interleukin-2 and interferon-α-2a outpatient therapy for metastatic renal cell carcinoma

Lipton, A., Harvey, H., Givant, E., Hopper, K., Lawler, J., Matthews, Y., Hirsh, M. & Zeffren, J., Jan 1 1993, In : Journal of Immunotherapy. 13, 2, p. 122-129 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Subcutaneous interleukin-2 plus interferon alfa-2a in metastatic renal cancer: An outpatient multicenter trial

Vogelzang, N. J., Lipton, A. & Figlin, R. A., Jan 1 1993, In : Journal of Clinical Oncology. 11, 9, p. 1809-1816 8 p.

Research output: Contribution to journalArticle

117 Scopus citations

The effects of long term fadrozole hydrochloride treatment in patients with advanced stage breast cancer

Demers, L., Lipton, A., Harvey, H., Hanagan, J., Mulagha, M. & Santen, R. J., Mar 1993, In : Journal of Steroid Biochemistry and Molecular Biology. 44, 4-6, p. 683-685 3 p.

Research output: Contribution to journalArticle

17 Scopus citations

The efficacy of CGS 20267 in suppressing estrogen biosynthesis in patients with advanced stage breast cancer

Demers, L. M., Lipton, A., Harvey, H. A., Kambic, K. B., Grossberg, H., Brady, C. & Santen, R. J., Mar 1993, In : Journal of Steroid Biochemistry and Molecular Biology. 44, 4-6, p. 687-691 5 p.

Research output: Contribution to journalArticle

82 Scopus citations
1992

Elevated soluble c-erbB-2 antigen levels in the serum and effusions of a proportion of breast cancer patients

Leitzel, K., Teramoto, Y., Sampson, E., Mouceri, J., Langten, B. C., Demers, L., Podczaski, E., Harvey, H., Shambaugh, S., Volas, G., Weaver, S. & Lipton, A., Jan 1 1992, In : Journal of Clinical Oncology. 10, 9, p. 1436-1443 8 p.

Research output: Contribution to journalArticle

130 Scopus citations

Hormonal and immunological regulation of 2′,5′-oligoadenylate synthetase activity in human peripheral blood mononuclear cells

Miele, M. B., Vesell, E. S., Ehmann, W. C., Lipton, A., Harvey, H. & Kan, N. C., Nov 1992, In : Clinical Immunology and Immunopathology. 65, 2, p. 183-192 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prognostic value of breast cancer aromatase

Lipton, A., Santen, R. J., Santner, S. J., Harvey, H. A., Sanders, S. I. & Matthews, Y. L., Oct 1 1992, In : Cancer. 70, 7, p. 1951-1955 5 p.

Research output: Contribution to journalArticle

69 Scopus citations
1991

Corynebacterium parvum versus bacille calmette-guérin adjuvant immunotherapy of stage II malignant melanoma

Lipton, A., Harvey, H. A., Balch, C. M., Antle, C. E., Heckard, R. & Bartolucci, A. A., Jan 1 1991, In : Journal of Clinical Oncology. 9, 7, p. 1151-1156 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Elevated Plasma Platelet-derived Growth Factor B-Chain Levels in Cancer Patients

Leitzel, K., Bryce, W., Tomita, J., Manderino, G., Tribby, I., Thomason, A., Billingsley, M., Podczaski, E., Harvey, H. & Lipton, A., Aug 15 1991, In : Cancer Research. 51, 16, p. 4149-4154 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Specificity of low dose fadrozole hydrochloride (CGS 16949A) as an aromatase inhibitor

Santen, R. J., Demers, L. M., Lynch, J., Harvey, H., Lipton, A., Mulagha, M., Hanagan, J., Garber, J. E., Henderson, I. C., Navari, R. M. & Miller, A. A., Jul 1991, In : Journal of Clinical Endocrinology and Metabolism. 73, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

44 Scopus citations
1990

A phase I trial of CGS 16949a. A new aromatase inhibitor

Lipton, A., Harvey, H. A., Demers, L. M., Hanagan, J. R., Mulagha, M. T., Kochak, G. M., Fitzsimmons, S., Sanders, S. I. & Santen, R. J., Mar 15 1990, In : Cancer. 65, 6, p. 1279-1285 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

FAM chemotherapy ± aminoglutethimide in the treatment of pancreatic carcinoma

Lipton, A., Harvey, H., Santen, R. J., Stryker, J. A., Barnes, S. G., Walker, B. K., Dixon, R. H., Givant, E. M., Bartholomew, M. J. & Nadjafi, C., Mar 23 1990, In : European Journal of Surgical Oncology. 16, 1, p. 12-14 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Phase I study of interleukin-2 and interferon alfa-2a as outpatient therapy for patients with advanced malignancy

Hirsh, M., Lipton, A., Harvey, H., Givant, E., Hopper, K., Jones, G., Zeffren, J. & Levitt, D., Jan 1 1990, In : Journal of Clinical Oncology. 8, 10, p. 1657-1663 7 p.

Research output: Contribution to journalArticle

62 Scopus citations

Somatostatin analogues in the treatment of breast and prostate cancer

Manni, A., Boucher, A. E., Demers, L. M., Harvey, H. A., Lipton, A., Simmonds, M. A. & Bartholomew, M., Dec 20 1990, In : Journal of Steroid Biochemistry and Molecular Biology. 37, 6, p. 1083-1087 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

The effects of CGS 16949A, an aromatase inhibitor on adrenal mineralocorticoid biosynthesis

Demers, L., Melby, J. C., Wilson, T. E., Lipton, A., Harvey, H. & Santen, R. J., Apr 1990, In : Journal of Clinical Endocrinology and Metabolism. 70, 4, p. 1162-1166 5 p.

Research output: Contribution to journalArticle

66 Scopus citations

The Pharmacodynamic Inhibition of Estrogen Synthesis by Fadrozole, an Aromatase Inhibitor, and Its Pharmacokinetic Disposition

Kochak, G. M., Mangat, S., Mulagha, M. T., Entwistle, E. A., Santen, R. J., Lipton, A. & Demers, L., Nov 1990, In : Journal of Clinical Endocrinology and Metabolism. 71, 5, p. 1349-1355 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
1989

A phase I study of hepatic arterial infusion using difluoromethylornithine

Lipton, A., Harvey, H. A., Glenn, J., Weidner, W. A., Strauss, M., Miller, S. E., Taylor, J. B., White‐Hershey, D. & Barlow, J. L. R., Feb 1 1989, In : Cancer. 63, 3, p. 433-437 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Chemotherapy plus RA223 in the treatment of oat cell lung cancer

Lipton, A., Harvey, H. A., Walker, B., Dixon, R., Valdivia, D., Barnes, S., Gordon, R., White-Hershey, D., Bartholomew, M. J., Warzawski, N. & Antle, C. E., Jan 1 1989, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 12, 3, p. 259-263 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Endocrine effects of combined somatostatin analog and bromocriptine therapy in women with advanced breast cancer

Manni, A., Boucher, A. E., Demers, L. M., Harvey, H. A., Lipton, A., Simmonds, M. A. & Bartholomew, M., Dec 1 1989, In : Breast Cancer Research and Treatment. 14, 3, p. 289-298 10 p.

Research output: Contribution to journalArticle

63 Scopus citations

Immunologic monitoring studies in advanced cancer patients treated with recombinant human gamma interferon (IFN-gamma 4A).

Romano, P. J., Lipton, A., Harvey, H., Bartholomew, M. J., Giudice, G., Kloszewski, F., Witkowski, L. & Downing, M. R., 1989, In : Molecular biotherapy. 1, 4, p. 208-212 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Predictors of grief among spouses of deceased cancer patients

Houts, P. S., Lipton, A., Harvey, H., Simmonds, M. A. & Bartholomew, M. J., Nov 7 1989, In : Journal of Psychosocial Oncology. 7, 3, p. 113-126 14 p.

Research output: Contribution to journalArticle

24 Scopus citations

The incidence and causes of job-related problems among employed people with cancer in pennsylvania

Houts, P. S., Kahn, S. B., Yasco, J. M., Hermann, J. F., Lipton, A., Schelzel, G. W., Marconi, K. M. & Bartholomew, M. J., Jul 6 1989, In : Journal of Psychosocial Oncology. 7, 1-2, p. 19-30 12 p.

Research output: Contribution to journalArticle

7 Scopus citations
1988

Androgen priming and chemotherapy in advanced prostate cancer: Evaluation of determinants of clinical outcome

Manni, A., Bartholomew, M., Caplan, R., Boucher, A., Santen, R., Lipton, A., Harvey, H., Simmonds, M., White-Hershey, D., Gordon, R., Rohner, T., Drago, J., Wettlaufer, J. & Glode, L., Jan 1 1988, In : Journal of Clinical Oncology. 6, 9, p. 1456-1466 11 p.

Research output: Contribution to journalArticle

87 Scopus citations

A phase I trial of recombinant human gamma interferon (IFN-γ4A) in patients with advanced malignancy

Perez, R., Lipton, A., Harvey, H. A., Simmonds, M. A., Romano, P. J., Imboden, S. L., Giudice, G., Downing, M. R. & Alton, N. K., Jun 1988, In : Journal of Biological Response Modifiers. 7, 3, p. 309-317 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Correlation of aromatase activity with histological differentiation of breast cancer - A morphometric analysis

Lipton, A., Santen, R. J., Santner, S. J., Harvey, H. A., White-Hershey, D., Bartholomew, M. J. & Sharkey, F. E., Sep 1 1988, In : Breast Cancer Research and Treatment. 12, 1, p. 31-35 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Marked heterogeneity of aromatase activity in human malignant melanoma tissue

Santen, R. J., Santner, S. J., Harvey, H., Lipton, A., Simmonds, M., Feil, P. D., Manders, E. & Davis, T. S., Dec 1988, In : European Journal of Cancer and Clinical Oncology. 24, 12, p. 1811-1816 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
1987

Addition of etoposide to cyclophosphamide, doxorubicin and vincristine for remission induction and survival in patients with small cell lung cancer

Messeih, A. A., Schweitzer, J. M., Lipton, A., Harvey, H. A., Simmonds, M. A., Stryker, J. A., Ricci, J. A., Hoffman, S. L., Gottleib, R. J. & Dixon, R. H., Mar 25 1987, In : Cancer Treatment Reports. 71, 1, p. 61-66 6 p.

Research output: Contribution to journalArticle

38 Scopus citations

Androgen depletion and repletion as a means of potentiating the effect of cytotoxic chemotherapy in advanced prostate cancer

Manni, A., Samten, R. J., Boucher, A. E., Lipton, A., Harvey, H., Simmonds, M., Gordon, R., Rohner, T., Drago, J., Wettlaufer, J. & Glode, L. M., 1987, In : Journal of Steroid Biochemistry. 27, 1-3, p. 551-556 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

A randomized trial of aminoglutethimide ± estrogen before chemotherapy in advanced breast cancer

Lipton, A., Santen, R. J., Harvey, H., Manni, A., Simmonds, M. A., White-Hershey, D., Bartholomew, M. J., Walker, B. K., Dixon, R. H. & Valdevia, D. E., Jan 1 1987, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 10, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

15 Scopus citations