• 664 Citations
  • 11 h-Index
20062020

Research output per year

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Personal profile

Research interests

The lab of Drs. Amanda Nelson and Diane Thiboutot is focused on understanding the skin-specific and immune mechanisms underlying inflammatory skin diseases associated with sebaceous glands and hair follicles, such as acne vulgaris and hidradenitis suppurativa. The lab is also interested in the role of innate immunity, specifically TLR signaling pathways, in normal keratinocytes and in non-melanoma skin cancer. Another focus of the laboratory is understanding the relationship between the skin microbiome, host immune response and changes that occur with the development of skin diseases or the treatment of skin diseases. Translational studies use cell culture, mouse models and samples from patients. The group uses its varied expertise in cell and molecular biology approaches and human subjects research to investigate the pathogenesis of skin diseases.

Teaching and educational interests

Dr. Amanda Nelson is a faculty member in the Biomedical Sciences (BMS) Graduate Program and the MD/PhD Medical Scientist Training Program at Penn State College of Medicine.

Education/Academic qualification

Postdoctoral Fellowship, Johns Hopkins University School of Medicine

20102013

Postdoctoral Fellowship, Penn State College of Medicine

20072010

PhD, Penn State College of Medicine

… → 2007

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Projects

  • Research Output

    Loss of Skin Microbial Diversity and Alteration of Bacterial Metabolic Function in Hidradenitis Suppurativa

    Schneider, A. M., Cook, L. C., Zhan, X., Banerjee, K., Cong, Z., Imamura-Kawasawa, Y., Gettle, S. L., Longenecker, A. L., Kirby, J. S. & Nelson, A. M., Mar 2020, In : Journal of Investigative Dermatology. 140, 3, p. 716-720 5 p.

    Research output: Contribution to journalArticle

    4 Scopus citations

    Response to Ring et al. In Silico Predictive Metagenomic Analyses Highlight Key Metabolic Pathways Impacted in the Hidradenitis Suppurativa Skin Microbiome

    Schneider, A. M., Cook, L. C., Zhan, X., Banerjee, K., Cong, Z., Imamura-Kawasawa, Y., Gettle, S. L., Longenecker, A. L., Kirby, J. S. & Nelson, A. M., 2020, (Accepted/In press) In : Journal of Investigative Dermatology.

    Research output: Contribution to journalArticle

    Association of Systemic Antibiotic Treatment of Acne with Skin Microbiota Characteristics

    Chien, A. L., Tsai, J., Leung, S., Mongodin, E. F., Nelson, A. M., Kang, S. & Garza, L. A., Apr 2019, In : JAMA Dermatology. 155, 4, p. 425-434 10 p.

    Research output: Contribution to journalArticle

  • 8 Scopus citations

    E-cadherin and p120ctn protein expression are lost in hidradenitis suppurativa lesions

    Nelson, A. M., Cong, Z., Gettle, S. L., Longenecker, A. L., Kidacki, M., Kirby, J. S., Adams, D. R., Stairs, D. B. & Danby, F. W., Jul 2019, In : Experimental Dermatology. 28, 7, p. 867-871 5 p.

    Research output: Contribution to journalArticle

  • Increased risk of alopecia areata for people with hidradenitis suppurativa in a cross-sectional study

    Horissian, M., Maczuga, S., Kirby, J. S. & Nelson, A. M., Dec 2019, In : Journal of the American Academy of Dermatology. 81, 6, p. 1431-1432 2 p.

    Research output: Contribution to journalArticle

    1 Scopus citations