• 612 Citations
  • 10 h-Index
20062021
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Personal profile

Research interests

The lab of Drs. Amanda Nelson and Diane Thiboutot is focused on understanding the skin-specific and immune mechanisms underlying inflammatory skin diseases associated with sebaceous glands and hair follicles, such as acne vulgaris and hidradenitis suppurativa. The lab is also interested in the role of innate immunity, specifically TLR signaling pathways, in normal keratinocytes and in non-melanoma skin cancer. Another focus of the laboratory is understanding the relationship between the skin microbiome, host immune response and changes that occur with the development of skin diseases or the treatment of skin diseases. Translational studies use cell culture, mouse models and samples from patients. The group uses its varied expertise in cell and molecular biology approaches and human subjects research to investigate the pathogenesis of skin diseases.

Teaching and educational interests

Dr. Amanda Nelson is a faculty member in the Biomedical Sciences (BMS) Graduate Program and the MD/PhD Medical Scientist Training Program at Penn State College of Medicine.

Education/Academic qualification

Postdoctoral Fellowship, Johns Hopkins University School of Medicine

20102013

Postdoctoral Fellowship, Penn State College of Medicine

20072010

PhD, Penn State College of Medicine

… → 2007

Fingerprint Dive into the research topics where Amanda Nelson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Acne Vulgaris Medicine & Life Sciences
Sebaceous Glands Medicine & Life Sciences
Isotretinoin Medicine & Life Sciences
Skin Medicine & Life Sciences
Hair Follicle Medicine & Life Sciences
Hidradenitis Suppurativa Medicine & Life Sciences
Microbiota Medicine & Life Sciences
Sebum Medicine & Life Sciences

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Projects 2012 2021

Toll-Like Receptor 3
Carcinogenesis
Homeostasis
Skin
Wounds and Injuries
Regeneration
Cytokines
Skin
Wounds and Injuries
Hair

Research Output 2006 2019

4 Citations (Scopus)

Association of Systemic Antibiotic Treatment of Acne with Skin Microbiota Characteristics

Chien, A. L., Tsai, J., Leung, S., Mongodin, E. F., Nelson, A. M., Kang, S. & Garza, L. A., Apr 2019, In : JAMA Dermatology. 155, 4, p. 425-434 10 p.

Research output: Contribution to journalArticle

Microbiota
Acne Vulgaris
Anti-Bacterial Agents
Skin
Minocycline

E-cadherin and p120ctn protein expression are lost in hidradenitis suppurativa lesions

Nelson, A., Cong, Z., Gettle, S. L., Longenecker, A. L., Kidacki, M., Sciacca Kirby, J., Adams, D., Stairs, D. & Danby, F. W., Jul 1 2019, In : Experimental Dermatology. 28, 7, p. 867-871 5 p.

Research output: Contribution to journalArticle

Hidradenitis Suppurativa
Cadherins
Skin
Catenins
Proteins

Increased risk of alopecia areata for people with hidradenitis suppurativa in a cross-sectional study

Horissian, M., Maczuga, S., Kirby, J. S. & Nelson, A. M., Dec 2019, In : Journal of the American Academy of Dermatology. 81, 6, p. 1431-1432 2 p.

Research output: Contribution to journalArticle

Hidradenitis Suppurativa
Alopecia Areata
Cross-Sectional Studies
3 Citations (Scopus)

Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3

Kim, D., Chen, R., Sheu, M., Kim, N., Kim, S., Islam, N., Wier, E. M., Wang, G., Li, A., Park, A., Son, W., Evans, B., Yu, V., Prizmic, V. P., Oh, E., Wang, Z., Yu, J., Huang, W., Archer, N. K., Hu, Z. & 10 others, Clemetson, N., Nelson, A. M., Chien, A., Okoye, G. A., Miller, L. S., Ghiaur, G., Kang, S., Jones, J. W., Kane, M. A. & Garza, L. A., Dec 1 2019, In : Nature communications. 10, 1, 2811.

Research output: Contribution to journalArticle

Open Access
Toll-Like Receptor 3
Hair Follicle
hair
Tretinoin
regeneration

Skin microbiota: Friend or foe in pediatric skin health and skin disease

Schneider, A. M. & Nelson, A. M., Jan 1 2019, (Accepted/In press) In : Pediatric dermatology.

Research output: Contribution to journalReview article

Microbiota
Skin Diseases
Pediatrics
Skin
Acne Vulgaris