• 621 Citations
  • 10 h-Index
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Personal profile

Research interests

The lab of Drs. Amanda Nelson and Diane Thiboutot is focused on understanding the skin-specific and immune mechanisms underlying inflammatory skin diseases associated with sebaceous glands and hair follicles, such as acne vulgaris and hidradenitis suppurativa. The lab is also interested in the role of innate immunity, specifically TLR signaling pathways, in normal keratinocytes and in non-melanoma skin cancer. Another focus of the laboratory is understanding the relationship between the skin microbiome, host immune response and changes that occur with the development of skin diseases or the treatment of skin diseases. Translational studies use cell culture, mouse models and samples from patients. The group uses its varied expertise in cell and molecular biology approaches and human subjects research to investigate the pathogenesis of skin diseases.

Teaching and educational interests

Dr. Amanda Nelson is a faculty member in the Biomedical Sciences (BMS) Graduate Program and the MD/PhD Medical Scientist Training Program at Penn State College of Medicine.

Education/Academic qualification

Postdoctoral Fellowship, Johns Hopkins University School of Medicine


Postdoctoral Fellowship, Penn State College of Medicine


PhD, Penn State College of Medicine

… → 2007

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  • 2 Similar Profiles
Acne Vulgaris Medicine & Life Sciences
Sebaceous Glands Medicine & Life Sciences
Isotretinoin Medicine & Life Sciences
Skin Medicine & Life Sciences
Hidradenitis Suppurativa Medicine & Life Sciences
Hair Follicle Medicine & Life Sciences
Microbiota Medicine & Life Sciences
Sebum Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2021

Toll-Like Receptor 3
Wounds and Injuries
Wounds and Injuries

Research Output 2006 2019

4 Citations (Scopus)

Association of Systemic Antibiotic Treatment of Acne with Skin Microbiota Characteristics

Chien, A. L., Tsai, J., Leung, S., Mongodin, E. F., Nelson, A. M., Kang, S. & Garza, L. A., Apr 2019, In : JAMA Dermatology. 155, 4, p. 425-434 10 p.

Research output: Contribution to journalArticle

Acne Vulgaris
Anti-Bacterial Agents

E-cadherin and p120ctn protein expression are lost in hidradenitis suppurativa lesions

Nelson, A., Cong, Z., Gettle, S. L., Longenecker, A. L., Kidacki, M., Sciacca Kirby, J., Adams, D., Stairs, D. & Danby, F. W., Jul 1 2019, In : Experimental Dermatology. 28, 7, p. 867-871 5 p.

Research output: Contribution to journalArticle

Hidradenitis Suppurativa

Increased risk of alopecia areata for people with hidradenitis suppurativa in a cross-sectional study

Horissian, M., Maczuga, S., Kirby, J. S. & Nelson, A. M., Dec 2019, In : Journal of the American Academy of Dermatology. 81, 6, p. 1431-1432 2 p.

Research output: Contribution to journalArticle

Hidradenitis Suppurativa
Alopecia Areata
Cross-Sectional Studies

Loss of Skin Microbial Diversity and Alteration of Bacterial Metabolic Function in Hidradenitis Suppurativa

Schneider, A. M., Cook, L. C., Zhan, X., Banerjee, K., Cong, Z., Imamura-Kawasawa, Y., Gettle, S. L., Longenecker, A. L., Kirby, J. S. & Nelson, A. M., Jan 1 2019, (Accepted/In press) In : Journal of Investigative Dermatology.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3

Kim, D., Chen, R., Sheu, M., Kim, N., Kim, S., Islam, N., Wier, E. M., Wang, G., Li, A., Park, A., Son, W., Evans, B., Yu, V., Prizmic, V. P., Oh, E., Wang, Z., Yu, J., Huang, W., Archer, N. K., Hu, Z. & 10 others, Clemetson, N., Nelson, A. M., Chien, A., Okoye, G. A., Miller, L. S., Ghiaur, G., Kang, S., Jones, J. W., Kane, M. A. & Garza, L. A., Dec 1 2019, In : Nature communications. 10, 1, 2811.

Research output: Contribution to journalArticle

Open Access
Toll-Like Receptor 3
Hair Follicle