Projects per year
Personal profile
Research interests
Dr. Anthony Bonavia's work focuses on the mechanisms of innate immune dysfunction caused by septic shock and associated acute kidney injury. Both of these diseases result in very high systemic levels of resistin, a pro-inflammatory cytokine impairing chemotaxis, reactive oxygen species production and bacterial killing by neutrophils. By using cell-based and animal models, Dr. Bonavia investigates whether resistin is responsible for immunosuppression in these disease states.
The translational implications of his research are to aid better understanding of whether cytokine adsorption therapy may have a role in mitigating the secondary infectious complications that develop in critically ill patients following sepsis and acute kidney injury.
Professional information
Board-certified in Anesthesiology and Critical Care Medicine, American Board of Anesthesiology
Board-certified in Advanced Perioperative Transesophageal Echocardiography, National Board of Echocardiography
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Critical Care Medicine, Fellowship, Duke University Medical Center
… → 2014
Anesthesiology, Residency, Cleveland Clinic
… → 2013
MD, Mount Sinai School of Medicine
… → 2009
BA (Hons), New York University
… → 2001
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Projects
- 1 Active
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Resistin-induced immunosuppression increases susceptibility to infectious lung injury and sepsis during AKI
National Institute of General Medical Sciences
8/1/20 → 7/31/23
Project: Research project
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Analysis of the American College of Surgeons National Surgical Quality Improvement Program® (ACS NSQIP®) Database to Identify Factors Associated with Postoperative Mortality After Elective Non-cardiac Surgery
Malviya, A. K., Bruceta, M., Singh, P. M., Bonavia, A., Karamchandani, K. & Gupta, A., Apr 2022, In: Indian Journal of Surgery. 84, p. 234-239 6 p.Research output: Contribution to journal › Article › peer-review
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Comparison of Rapid Cytokine Immunoassays for Functional Immune Phenotyping
Bonavia, A. S., Samuelsen, A., Chroneos, Z. C. & Halstead, E. S., Jul 4 2022, In: Frontiers in immunology. 13, 940030.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Failure to Rescue After Severe Acute Kidney Injury in Patients Undergoing Non–Cardiac Surgery
Karamchandani, K., McDowell, B. J., Raghunathan, K., Krishnamoorthy, V., Lehman, E. B., Ohnuma, T. & Bonavia, A., Nov 2022, In: Journal of Surgical Research. 279, p. 148-163 16 p.Research output: Contribution to journal › Article › peer-review
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Integrated machine learning approaches for flow cytometric quantification of myeloid-derived suppressor cells in acute sepsis
Bonavia, A. S., Samuelsen, A., Luthy, J. & Halstead, E. S., Nov 17 2022, In: Frontiers in immunology. 13, 1007016.Research output: Contribution to journal › Article › peer-review
Open Access -
Non-operating room anesthesia in the intensive care unit
Bonavia, A., Abdelmalak, B. & Karamchandani, K., Jun 2022, In: Journal of Clinical Anesthesia. 78, 110668.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations
Prizes
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Dean's Award for Excellence in Teaching
Aprile, Bettina (Recipient), Aumiller, Betsy B. (Recipient), Berkey, Franklin (Recipient), Bonavia, Anthony (Recipient), Booth, Jennifer (Recipient), Brennan, Kristin (Recipient), Browning, Kirsteen (Recipient), Buchkovich, Nicholas (Recipient), Butt, Fauzia K. (Recipient), Carrel, Laura (Recipient), Choe, Angela (Recipient), Clarke, Sheila (Recipient), Coleman, Melissa (Recipient), Dalke, Katharine (Recipient), Devaraj, Tara (Recipient), Duryea, Stacey (Recipient), Enama, Joseph (Recipient), Evey, Loren (Recipient), Finch, Elizabeth (Recipient), Fischer, Michelle (Recipient), Gallo, Robert (Recipient), Gavigan, Patrick (Recipient), Ghaffari, Gisoo (Recipient), Go, Pauline (Recipient), Grana, Jennifer (Recipient), Greensmith, James (Recipient), Grogan, James (Recipient), Hajnal, Andras (Recipient), Helm, Matthew (Recipient), Hempel, Nadine (Recipient), Imamura, Fumiaki (Recipient), Jain, Rohit (Recipient), Jeganathan, Nimalan (Recipient), Kelle, Angela (Recipient), Kumar, Ashutosh (Recipient), Kwun, Hyun Jin (Recipient), Lang, Charles (Recipient), Lutzkanin, Andrew (Recipient), Martin, Kathryn (Recipient), McGarrity, Thomas (Recipient), McHale, Katie (Recipient), McLaughlin, Patricia (Recipient), Mormando, Charles (Recipient), Nguyen, Joseph (Recipient), Nickolich, Myles (Recipient), Ouyang, Tao (Recipient), Pachuski, Justin (Recipient), Polimera, Hyma (Recipient), Potochny, Evelyn (Recipient), Rakszawski, Kevin L. (Recipient), Reyes, Lilia (Recipient), Sankoorikal, Binu-john (Recipient), Shantz, Lisa (Recipient), Singh, Madhavi (Recipient), Songdej, Natthapol (Recipient), Spotts, Ryan (Recipient), Swigart, Alison (Recipient), Varner, Malina (Recipient), Verma, Navin (Recipient), Walter, Vonn (Recipient), Wang, Che-Yen "Joseph" (Recipient), Warfield, Dennis (Recipient), Wilson, Meghan N. (Recipient) & Hussein, Rezhan (Recipient), 2021
Prize
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Dean's Award for Excellence in Teaching
McAlevy, Mary (Recipient), Bonavia, Anthony (Recipient), Malhotra, Anita (Recipient), Weller, Gregory E. (Recipient), Waning, David (Recipient), Lanza, Matthew (Recipient), Ken, Kimberly (Recipient), McCarver, Stewart (Recipient), Glasser, Joshua (Recipient), Schooler, Jordan (Recipient), Lewis, Sarah (Recipient), Onks, Cayce (Recipient), Rao, Ravishankar (Recipient), Nickolich, Sarah (Recipient), Helm, Leesha (Recipient), Critchfield, Laura (Recipient), Myers, Kimberly (Recipient), Green, Michael (Recipient), Songdej, Natthapol (Recipient), Narayana, Shyam (Recipient), Razjouyan, Hadie (Recipient), Duca, Nicholas (Recipient), Casas, Rachel (Recipient), Cooper, Jennifer (Recipient), Wright, Rollin (Recipient), Karasinski, Amanda (Recipient), Probolus, James Andrew "Andy" (Recipient), Madara, John (Recipient), Guck, Daniel (Recipient), Ingram, David (Recipient), De Obaldia, Anna (Recipient), Hussein, Rezhan (Recipient), McGillen, Brian (Recipient), Chapman, Tyler (Recipient), Munyon, Ryan (Recipient), Kinard, Shane R. (Recipient), Banks, Sharon (Recipient), Genao, Inginia (Recipient), McShane, Michael (Recipient), Allie, S. Rameeza (Recipient), Silberman, Yuval (Recipient), Evey, Loren (Recipient), McLaughlin, Patricia (Recipient), Grogan, James (Recipient), Nguyen, Joseph (Recipient), Donato, Heather (Recipient), Fox, Edward (Recipient), Gniady, John (Recipient), Oladipo, Olajumoke (Recipient), Abendroth, Catherine (Recipient), Keefer, Laura (Recipient), Massare, Brittany (Recipient), Undar, Akif (Recipient), Mondal, Pritish (Recipient), Mainali, Gayatra (Recipient), Jhaveri, Pooja (Recipient), Freiberg, Andrew (Recipient), Levenson, Robert (Recipient), Mailman, Richard (Recipient), Boodoo, Ramnarine (Recipient), Francis, Andrew (Recipient), Hameed, Usman (Recipient), Yadav, Sanjay (Recipient), Calo, William (Recipient), Pinto, Casey (Recipient), Cooper, Amanda (Recipient), Kulaylat, Audrey (Recipient), Scow, Jeffrey (Recipient), Roberts, John (Recipient), Winder, Joshua (Recipient), Aminsharifi, Alireza (Recipient), Adams, Nancy (Recipient) & van Riggelen, Jan (Recipient), 2023
Prize