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1965 …2018
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Research Output 1965 2018

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Article
1967
7 Citations (Scopus)

The effect of trypsin digestion and ionic strength on RNA polymerase of rat liver

Pegg, A. E. & Korner, A., Feb 1967, In : Archives of Biochemistry and Biophysics. 118, 2, p. 362-366 5 p.

Research output: Contribution to journalArticle

DNA-Directed RNA Polymerases
Ionic strength
Liver
Osmolar Concentration
Trypsin
1968
273 Citations (Scopus)

Biosynthesis of putrescine in the prostate gland of the rat.

Pegg, A. E. & Williams-Ashman, H. G., Jul 1968, In : The Biochemical journal. 108, 4, p. 533-539 7 p.

Research output: Contribution to journalArticle

Carbon Isotopes
Chemical Stimulation
Pyridoxal Phosphate
Ornithine
Carboxy-Lyases
9 Citations (Scopus)

Effects of androgens on incorporation of labeled amino acids into proteins by prostate mitochondria.

Pegg, A. E. & Williams-Ashman, H. G., Mar 1968, In : Endocrinology. 82, 3, p. 603-610 8 p.

Research output: Contribution to journalArticle

Pyruvates
Succinates
Carbon Isotopes
Pyruvate Kinase
Isoleucine
33 Citations (Scopus)

Rapid effects of testosterone in prostatic polyamine-synthesizing enzyme systems.

Pegg, A. & Williams-Ashman, H. G., Sep 1 1968, In : Biochemical Journal. 109, 3

Research output: Contribution to journalArticle

Carboxy-Lyases
Spermine
Polyamines
Amines
Testosterone
59 Citations (Scopus)

Stimulation of the decarboxylation of S-adenosylmethionine by putrescine in mammalian tissues

Pegg, A. E. & Williams-Ashman, H. G., Jan 11 1968, In : Biochemical and Biophysical Research Communications. 30, 1, p. 76-82 7 p.

Research output: Contribution to journalArticle

Chemical Depression
Isonicotinic Acids
Carbon Isotopes
Chemical Stimulation
S-Adenosylmethionine
1969
112 Citations (Scopus)

Mechanisms and regulation of polyamine and putrescine biosynthesis in male genital glands and other tissues of mammals

Williams-Ashman, H. G., Pegg, A. E. & Lockwood, D. H., 1969, In : Advances in enzyme regulation. 7, C, p. 291-323 33 p.

Research output: Contribution to journalArticle

Putrescine
Spermidine
Polyamines
Prostate
Mammals
311 Citations (Scopus)

On the role of S-adenosyl-L-methionine in the biosynthesis of spermidine by rat prostate.

Pegg, A. & Williams-Ashman, H. G., Feb 25 1969, In : Journal of Biological Chemistry. 244, 4, p. 682-693 12 p.

Research output: Contribution to journalArticle

Carbon Isotopes
S-Adenosylmethionine
Carboxy-Lyases
Spermidine
Seminal Vesicles
137 Citations (Scopus)

Phosphate-stimulated breakdown of 5'-methylthioadenosine by rat ventral prostate.

Pegg, A. E. & Williams-Ashman, H. G., Nov 1969, In : The Biochemical journal. 115, 2, p. 241-247 7 p.

Research output: Contribution to journalArticle

Carbon Isotopes
Chemical Stimulation
Ribose
Adenine
Transferases
1970
24 Citations (Scopus)

BIOSYNTHESIS OF PUTRESCINE AND POLYAMINES IN MAMMALIAN TISSUES

Pegg, A., Jan 1 1970, In : Annals of the New York Academy of Sciences. 171, 3, p. 977-987 11 p.

Research output: Contribution to journalArticle

Putrescine
Polyamines
225 Citations (Scopus)

Concentrations of putrescine and polyamines and their enzymic synthesis during androgen-induced prostatic growth.

Pegg, A., Lockwood, D. H. & Williams-Ashman, H. G., Jan 1 1970, In : The Biochemical journal. 117, 1, p. 17-31 15 p.

Research output: Contribution to journalArticle

Butylamines
Arginase
Ornithine
Carboxy-Lyases
Putrescine
47 Citations (Scopus)

Enzymic synthesis of spermine in rat prostate

Pegg, A. E. & Williams-Ashman, H. G., Mar 1970, In : Archives of Biochemistry and Biophysics. 137, 1, p. 156-165 10 p.

Research output: Contribution to journalArticle

Spermine
Rats
Prostate
Spermidine
Methionine
1971
42 Citations (Scopus)

Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine.

Swann, P. F., Pegg, A. E., Hawks, A., Farber, E. & Magee, P. N., Jun 1971, In : The Biochemical journal. 123, 2, p. 175-181 7 p.

Research output: Contribution to journalArticle

Ethionine
Tritium
Alkylation
Guanine
Methionine
22 Citations (Scopus)
Hydrazines
1,2-Dimethylhydrazine
Methylation
Methyltransferases
Transfer RNA
44 Citations (Scopus)

Studies on inhibitors of mammalian tRNA methylases

Pegg, A. E., Jul 15 1971, In : FEBS Letters. 16, 1, p. 13-16 4 p.

Research output: Contribution to journalArticle

Transfer RNA
49 Citations (Scopus)

The effects of diamines and polyamines on enzymic methylation of nucleic acid

Pegg, A. E., Apr 8 1971, In : BBA Section Nucleic Acids And Protein Synthesis. 232, 4, p. 630-642 13 p.

Research output: Contribution to journalArticle

Diamines
Polyamines
Nucleic Acids
Methylation
Transfer RNA
1972
14 Citations (Scopus)

Base composition of normal and megaloblastic bone marrow DNA

Hoffbrand, A. V. & Pegg, A. E., Feb 9 1972, In : Nature New Biology. 235, 58, p. 187-188 2 p.

Research output: Contribution to journalArticle

Macrocytic Anemia
Folic Acid Deficiency
Vitamin B 12 Deficiency
Cytidine
Thymine
11 Citations (Scopus)
Dimethylnitrosamine
Transfer RNA
Carcinogens
Kidney
Neoplasms
14 Citations (Scopus)
Transfer RNA
Methylation
5-Methylcytosine
Kidney
Neoplasms
8 Citations (Scopus)

Methylation of yeast aspartic acid transfer RNA by rat liver extracts

Pegg, A., May 15 1972, In : FEBS Letters. 22, 3, p. 339-342 4 p.

Research output: Contribution to journalArticle

Liver Extracts
Transfer RNA
Aspartic Acid
Methylation
Yeasts
3 Citations (Scopus)
Hydrazines
1,2-Dimethylhydrazine
Methylation
Methyltransferases
Transfer RNA
30 Citations (Scopus)

Studies of the ethylation of rat liver transfer ribonucleic acid after administration of L-ethionine.

Pegg, A. E., Jun 1972, In : The Biochemical journal. 128, 1, p. 59-68 10 p.

Research output: Contribution to journalArticle

Bacterial RNA
Carbon Isotopes
Ethionine
Pyrimidines
Ribose
1973
22 Citations (Scopus)

Alkylation of transfer RNA by N-methyl-N-nitrosourea and N-ethyl-N-nitrosourea

Pegg, A. E., Jun 1973, In : Chemico-Biological Interactions. 6, 6, p. 393-406 14 p.

Research output: Contribution to journalArticle

Ethylnitrosourea
Methylnitrosourea
Alkylation
Transfer RNA
Nucleic Acids
33 Citations (Scopus)

A reappraisal of the effects of adenosine 3':5'-cyclic monophosphate on the function and morphology of the rat prostate gland.

Mangan, F. R., Pegg, A. E. & Mainwaring, I. P., May 1973, In : The Biochemical journal. 134, 1, p. 129-142 14 p.

Research output: Contribution to journalArticle

Cyproterone
Ultraviolet Spectrophotometry
S-Adenosylmethionine
Ornithine
Carboxy-Lyases
54 Citations (Scopus)

Effect of inhibition of spermidine formation on protein and nucleic acid synthesis during lymphocyte activation

Kay, J. E. & Pegg, A., Feb 1 1973, In : FEBS Letters. 29, 3, p. 301-304 4 p.

Research output: Contribution to journalArticle

Spermidine
Lymphocytes
Nucleic Acids
Chemical activation
Proteins
43 Citations (Scopus)

Inhibition of spermidine formation in rat liver and kidney by methylglyoxal bis(guanylhydrazone).

Pegg, A. E., Mar 1973, In : The Biochemical journal. 132, 3, p. 537-540 4 p.

Research output: Contribution to journalArticle

Mitoguazone
Amidines
Glyoxal
Carbon Isotopes
Hydrazones
9 Citations (Scopus)
Mestranol
Liver Extracts
Transfer RNA
Methylation
Yeasts
59 Citations (Scopus)
Adenosylmethionine Decarboxylase
Rats
Tissue
Kidney
Enzymes
1974
6 Citations (Scopus)
Guanidines
Mitoguazone
Adenosylmethionine Decarboxylase
Glyoxal
Hydrazones
13 Citations (Scopus)

Further investigation of the increased transfer ribonucleic acid methylase activity in tumours of the mouse colon

Pegg, A. E. & Hawks, A. M., Jan 1 1974, In : Biochemical Journal. 137, 2, p. 229-238 10 p.

Research output: Contribution to journalArticle

Transfer RNA
Tumors
Colon
Methylation
Neoplasms
56 Citations (Scopus)

Purification of rat liver S adenosyl L methionine decarboxylase

Pegg, A. E., Jan 1 1974, In : Biochemical Journal. 141, 2, p. 581-583 3 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Liver
Purification
Rats
Spermidine Synthase
16 Citations (Scopus)
1,2-Dimethylhydrazine
Dimethylnitrosamine
Methylation
Transfer RNA
Tumors
1975
38 Citations (Scopus)

Alkylating intermediates in nitrosamine metabolism

Magee, P. N., Nicoll, J. W., Pegg, A. & Swann, P. F., Dec 1 1975, In : Biochemical Society transactions. 3, 1, p. 62-65 4 p.

Research output: Contribution to journalArticle

Ethylnitrosourea
Dimethylnitrosamine
Nitrosamines
Alkylating Agents
Guanine
187 Citations (Scopus)

Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA

Nicoll, J. W., Swann, P. F. & Pegg, A., Dec 1 1975, In : Nature. 254, 5497, p. 261-262 2 p.

Research output: Contribution to journalArticle

Dimethylnitrosamine
Guanine
Kidney
Liver
DNA
37 Citations (Scopus)

Methylation of rat liver mitochondrial deoxyribonucleic acid by chemical carcinogens and associated alterations in physical properties

Wilkinson, R., Hawks, A. & Pegg, A. E., Mar 1975, In : Chemico-Biological Interactions. 10, 3, p. 157-167 11 p.

Research output: Contribution to journalArticle

Methylation
Mitochondrial DNA
Carcinogens
Liver
Rats
174 Citations (Scopus)

Resuscitation of the monkey brain after one hour complete ischemia. III. Indications of metabolic recovery

Kleihues, P., Hossmann, K. A., Pegg, A. E., Kobayashi, K. & Zimmermann, V., Sep 12 1975, In : Brain research. 95, 1, p. 61-73 13 p.

Research output: Contribution to journalArticle

Polyribosomes
Resuscitation
Haplorhini
Ischemia
Brain Ischemia
8 Citations (Scopus)
tRNA Methyltransferases
Base Composition
Transfer RNA
Cricetinae
Liver
1976
4 Citations (Scopus)

Alkylation of messenger RNA by dimethylnitrosamine

Pegg, A. & Jackson, A., Jan 1 1976, In : Chemico-Biological Interactions. 12, 3-4, p. 279-284 6 p.

Research output: Contribution to journalArticle

Dimethylnitrosamine
Alkylation
Methyl Methanesulfonate
Nuclear RNA
Ribosomal RNA
2 Citations (Scopus)

Importance of DNA repair in the organ specificity of tumour induction by N nitroso carcinogens

Pegg, A. E., Nicoll, J. W., Magee, P. N. & Swann, P. F., Jan 1 1976, In : Unknown Journal. No. 376, p. 39-54 16 p.

Research output: Contribution to journalArticle

Organ Specificity
DNA Repair
Carcinogens
Nitrosamines
DNA
25 Citations (Scopus)
Adenosylmethionine Decarboxylase
Putrescine
Liver
Yeast
Rats
54 Citations (Scopus)
Nitrosamines
Dimethylnitrosamine
Carcinogenesis
Diethylnitrosamine
DNA
11 Citations (Scopus)

Starvation results in decreased initiation factor activity in rat skeletal muscle

Eugene Rannels, D., Pegg, A. & Rannels, S. R., Oct 18 1976, In : Biochemical and Biophysical Research Communications. 72, 4, p. 1481-1489 9 p.

Research output: Contribution to journalArticle

Peptide Initiation Factors
Starvation
Guanosine Triphosphate
Muscle
Rats
1977
101 Citations (Scopus)
Dimethylnitrosamine
Alkylation
Liver
DNA
Guanine

Differential effects of glucocorticoids on initiation of protein synthesis in skeletal muscle and heart

Rannels, S. R., Rannels, D. E., Pegg, A. E. & Jefferson, L. S., Jan 1 1977, In : Federation Proceedings. 36, 3, p. No. 1651

Research output: Contribution to journalArticle

Glucocorticoids
Skeletal Muscle
Proteins
38 Citations (Scopus)

Evidence for the presence of pyruvate in rat liver S-adenosylmethionine decarboxylase

Pegg, A. E., Dec 1 1977, In : FEBS Letters. 84, 1, p. 33-36 4 p.

Research output: Contribution to journalArticle

Pyruvates
Adenosylmethionine Decarboxylase
Carboxy-Lyases
Coenzymes
Pyruvic Acid
1,2-Dimethylhydrazine
Dimethylnitrosamine
Liver
DNA
O-(6)-methylguanine
307 Citations (Scopus)
Nitroso Compounds
Alkylating Agents
Nucleosides
Nucleic Acids
Carcinogenesis
102 Citations (Scopus)

Formation of 06-Methylguanine by Alkylation of Rat Liver, Colon, and Kidney DNA following Administration of 1, 2-Dimethylhydrazine

Rogers, K. J. & Pegg, A., Jan 1 1977, In : Cancer Research. 37, 11, p. 4082-4087 6 p.

Research output: Contribution to journalArticle

1,2-Dimethylhydrazine
Alkylation
Colon
Kidney
Liver

Growth hormone stimulation of ornithine decarboxylase activity in isolated rat hepatocytes

Jefferson, L. S., Freifeld, A. G. & Pegg, A. E., Jan 1 1977, In : Federation Proceedings. 36, 3, p. No.3373

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Growth Hormone
Hepatocytes

Inhibition of S-adenosylmethionine decarboxylase activity and polyamine synthesis in vivo

Pegg, A. E., Conover, C. & Wiegand, L., Jan 1 1977, In : Federation Proceedings. 36, 3, p. No.3431

Research output: Contribution to journalArticle

Adenosylmethionine Decarboxylase
Polyamines
10 Citations (Scopus)

Involvement of polyamines in the progestin-induced stimulation of endometrial glycogen synthesis during organ culture

Feil, P. D., Pegg, A., Demers, L. & Bardin, C. W., Mar 7 1977, In : Biochemical and Biophysical Research Communications. 75, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Organ Culture Techniques
Polyamines
Progestins
Glycogen
Spermidine