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1965 …2018
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Research Output 1965 2018

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Article
1985
20 Citations (Scopus)

Interaction of paraquat and amine uptake by rat lungs perfused in situ

Rannels, D. E., Pegg, A. E., Clark, R. S. & Addison, J. L., Jan 1 1985, In : American Journal of Physiology - Endocrinology and Metabolism. 12, 5, p. E506-E513

Research output: Contribution to journalArticle

Paraquat
Amines
Lung
Mitoguazone
Pulmonary Circulation

Interactions in uptake of paraquat and amines by perfused rat lungs

Rannels, D. E., Pegg, A. E. & Addison, J. L., Jan 1 1985, In : Federation Proceedings. 44, 6, p. No. 8644

Research output: Contribution to journalArticle

Investigation of the mechanism of regulation of S-adenosylmethionine decarboxylase by spermidine

Shirahata, A. & Pegg, A. E., Jan 1 1985, In : Federation Proceedings. 44, 5, p. No. 6289

Research output: Contribution to journalArticle

Adenosylmethionine Decarboxylase
Spermidine
14 Citations (Scopus)

Purification and characterization of some metabolic effects of S-neplanocylmethionine

Keller, B. T., Clark, R. S., Pegg, A. E. & Borchardt, R. T., Dec 1 1985, In : Molecular pharmacology. 28, 4, p. 364-370 7 p.

Research output: Contribution to journalArticle

Adenosylmethionine Decarboxylase
S-Adenosylmethionine
Protein O-Methyltransferase
Cycloleucine
Putrescine

Purification and characterization of some metabolic effects of S-neplanocylmethionine

Keller, B. T., Clark, R. S., Pegg, A. E. & Borchardt, R. T., Jan 1 1985, In : Federation Proceedings. 44, 5, p. No. 6950

Research output: Contribution to journalArticle

S-neplanocylmethionine
24 Citations (Scopus)

Quantitation of S-Adenosylmethionine Decarboxylase Protein

Shirahata, A., Christman, K. L. & Pegg, A., Jul 1 1985, In : Biochemistry. 24, 16, p. 4417-4423 7 p.

Research output: Contribution to journalArticle

Adenosylmethionine Decarboxylase
Radioimmunoassay
3T3 Cells
Proteins
Cell Extracts
HeLa Cells
DNA alkyltransferase
85 Citations (Scopus)

Reduction of O6-Alkylguanine-DNA Alkyltransferase Activity in HeLa Cells Treated with O6-Alkylguanines

Dolan, M. E., Morimoto, K. & Pegg, A., Dec 1 1985, In : Cancer Research. 45, p. 6413-6417 5 p.

Research output: Contribution to journalArticle

HeLa Cells
Alkyl and Aryl Transferases
Proteins
Guanine
Nucleic Acid Synthesis Inhibitors
51 Citations (Scopus)

Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate

Shirahata, A. & Pegg, A., Dec 1 1985, In : Journal of Biological Chemistry. 260, 17, p. 9583-9588 6 p.

Research output: Contribution to journalArticle

Mitoguazone
Adenosylmethionine Decarboxylase
Immunosorbent Techniques
Inbred Strains Rats
Eflornithine
90 Citations (Scopus)

Repair of o-propylguanine and o-butylguanine in dna by o-alkylguanine-dna alkyltransferases from rat liver and E. coli

Morimoto, K., Dolan, M. E., Scicchitano, D. & Pegg, A., Jul 1 1985, In : Carcinogenesis. 6, 7, p. 1027-1031 5 p.

Research output: Contribution to journalArticle

Alkyl and Aryl Transferases
Escherichia coli
Liver
Escherichia coli Proteins
Alkylating Agents
54 Citations (Scopus)

Studies of the repair of O6-alkylguanine and O4-alkylthymine in DNA by alkyltransferases from mammalian cells and bacteria

Pegg, A. E., Dolan, M. E., Scicchitano, D. & Morimoto, K., Jan 1 1985, In : Environmental health perspectives. VOL. 62, p. 109-114 6 p.

Research output: Contribution to journalArticle

Alkyl and Aryl Transferases
Bacteria
Liver
Alkylating Agents
DNA
7 Citations (Scopus)

The in vitro interaction of α-difluoromethyl ornithine (DFMO) and several interferons on human cell lines

Wolf, L. M., Leitzel, K. E., Pegg, A. E., Harvey, H. A. & Lipton, A., Aug 1985, In : Journal of Biological Response Modifiers. 4, 4, p. 391-395 5 p.

Research output: Contribution to journalArticle

Ornithine
Interferons
Cell Line
Melanoma
Growth
1984
10 Citations (Scopus)
RNA Polymerase I
Phosphorylation
Ornithine Decarboxylase
Nuclear Proteins
Phosphotransferases
23 Citations (Scopus)

Autoradiographic localization of ornithine decarboxylase in mouse kidney by use of radiolabeled α-difluoromethylornithine

Zagon, I. S., McLaughlin1, P. J., Seely, J. E., Hoeksema, G. W. & Pegg, A. E., Feb 1 1984, In : Cell And Tissue Research. 235, 2, p. 371-377 7 p.

Research output: Contribution to journalArticle

Eflornithine
Ornithine Decarboxylase
Kidney
Enzymes
Cytoplasm
43 Citations (Scopus)

Comparison of repair of methylated pyrimidines in poly(dT) by extracts from rat liver and Escherichia coli

Dolan, M. E., Scicchitano, D., Singer, B. & Pegg, A., Aug 30 1984, In : Biochemical and Biophysical Research Communications. 123, 1, p. 324-330 7 p.

Research output: Contribution to journalArticle

Poly T
Liver Extracts
Pyrimidines
Liver
Escherichia coli
109 Citations (Scopus)

Comparison of the Rates off Repair off O6-Alkylguanines in DNA by Rat Liver and Bacterial O6-Alkylguanine-DNA Alkyltransferase

Pegg, A. E., Scicchitano, D. & Dolan, M. E., Sep 1 1984, In : Cancer Research. 44, 9, p. 3806-3811 6 p.

Research output: Contribution to journalArticle

Guanine
Diethylnitrosamine
Alkyl and Aryl Transferases
Liver
DNA
138 Citations (Scopus)

Correlation between o-methylguanine-DNA-methyltransferase activity and resistance of human cells to the cytotoxic and mutagenic effect of N-methyl-n'-nitro-N-nitrosoguanidine

Domoradzki, J., Pegg, A., Dolan, M. E., Maher, V. M. & Mccormick, J. J., Dec 1 1984, In : Carcinogenesis. 5, 12, p. 1641-1647 7 p.

Research output: Contribution to journalArticle

Nitrosoguanidines
Methyltransferases
Human Activities
Gardner Syndrome
Adenomatous Polyposis Coli
45 Citations (Scopus)

Differential Inhibition of Histone and Polyamine Acetylases by Multisubstrate Analogues

Erwin, B. G., Persson, L. & Pegg, A. E., Aug 1984, In : Biochemistry. 23, 18, p. 4250-4255 6 p.

Research output: Contribution to journalArticle

Acetylesterase
Histone Acetyltransferases
Spermidine
Polyamines
Histones
53 Citations (Scopus)

Investigation of Structure and Rate of Synthesis of Ornithine Decarboxylase Protein in Mouse Kidney

Persson, L., Seely, J. E. & Pegg, A., Jan 1 1984, In : Biochemistry. 23, 16, p. 3777-3783 7 p.

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Kidney
Proteins
Enzymes
Androgens
235 Citations (Scopus)
O(6)-Methylguanine-DNA Methyltransferase
Neoplastic Cell Transformation
Pyrimidines
Alkylating Agents
Guanine
134 Citations (Scopus)

O6-alkylguanine-DNA alkyltransferase activity in human brain and brain tumors

Wiestler, O., Kleihues, P. & Pegg, A., Jan 1 1984, In : Carcinogenesis. 5, 1, p. 121-124 4 p.

Research output: Contribution to journalArticle

Human Activities
Brain Neoplasms
Brain
Alkyl and Aryl Transferases
Liver
96 Citations (Scopus)

O6-alkylguanine-DNA alkyltransferase activity in normal human tissues and cells

Harris, C. C., Pegg, A., Grafstrom, R. C. & Trump, B. F., Jul 1 1984, In : Cancer Research. 44, 7, p. 2855-2857 3 p.

Research output: Contribution to journalArticle

Alkyl and Aryl Transferases
Lung
Colon
DNA
Fibroblasts
21 Citations (Scopus)

Possible factors in the potentiation of 1-(2-chloroethy)-3-trans-4-methylcyclohexyl-1-nitrosourea cytotoxicity by α-difluoromethylornithine in 9L rat brain tumor cells

Oredsson, S. M., Pegg, A. E., Alhonen-Hongisto, L., Deen, D. F. & Marton, L. J., Apr 1984, In : European Journal of Cancer and Clinical Oncology. 20, 4, p. 535-542 8 p.

Research output: Contribution to journalArticle

Eflornithine
Polyamines
Brain Neoplasms
Putrescine
Methionine
11 Citations (Scopus)
Mitoguazone
Carmustine
Brain Neoplasms
Methionine
Eflornithine
11 Citations (Scopus)

Properties of the O6-alkylguanine-DNA repair system of mammalian cells.

Pegg, A., Dec 1 1984, In : IARC scientific publications. 57, p. 575-580 6 p.

Research output: Contribution to journalArticle

DNA Repair
Proteins
Rodentia
DNA
Cysteine
26 Citations (Scopus)

Role of polyamines in differentiation of 3T3-L1 fibroblasts into adipocytes

Erwin, B. G., Bethell, D. R. & Pegg, A. E., Jan 1 1984, In : American Journal of Physiology - Cell Physiology. 15, 2, p. C293-C300

Research output: Contribution to journalArticle

Spermidine
Polyamines
Adipocytes
Fibroblasts
Eflornithine
50 Citations (Scopus)

S‐Adenosylmethionine decarboxylase: A brief review

Pegg, A., Jan 1 1984, In : Cell Biochemistry and Function. 2, 1, p. 11-15 5 p.

Research output: Contribution to journalArticle

Adenosylmethionine Decarboxylase
S-Adenosylmethionine
Carboxy-Lyases
Polyamines
3 Citations (Scopus)

Saturation of repair system for O6-methylguanine in rat liver DNA by pretreatment with cyclic nitrosamines

Pegg, A. E. & Lijinsky, W., Oct 1984, In : Chemico-Biological Interactions. 51, 3, p. 365-370 6 p.

Research output: Contribution to journalArticle

Nitrosamines
Liver
Rats
Repair
DNA
7 Citations (Scopus)

Stereochemistry of the decarboxylation of l-ornithine with ornithine decarboxylase from mouse kidney

Orr, G. R., Gould, S. J., Pegg, A., Seely, J. E. & Coward, J. K., Jan 1 1984, In : Bioorganic Chemistry. 12, 3, p. 252-258 7 p.

Research output: Contribution to journalArticle

Stereochemistry
Decarboxylation
Ornithine
Ornithine Decarboxylase
Putrescine

Studies of mouse kidney ornithine decarboxylase (ODC)

Pegg, A. E., Jan 1 1984, In : Federation Proceedings. 43, 6, p. no. 2298

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Kidney
74 Citations (Scopus)

Studies of the induction of spermidine/spermine N1-acetyltransferase using a specific antiserum

Persson, L. & Pegg, A., Dec 1 1984, In : Journal of Biological Chemistry. 259, 20, p. 12364-12367 4 p.

Research output: Contribution to journalArticle

Acetyltransferases
Spermidine
Spermine
Immune Sera
Thioacetamide
48 Citations (Scopus)
Eflornithine
3T3 Cells
Polyamines
Spermine
Spermidine
35 Citations (Scopus)

The role of polyamines in somatomedin‐stimulated differentiation of L6 myoblasts

Ewton, D. Z., Erwin, B. G., Pegg, A. E. & Florini, J. R., Sep 1984, In : Journal of Cellular Physiology. 120, 3, p. 263-270 8 p.

Research output: Contribution to journalArticle

Insulin-Like Growth Factor II
Myoblasts
Polyamines
Somatomedins
Ornithine Decarboxylase

Use of specific antibodies and inhibitors to study spermidine/spermine N1-acetyltransferase (SAT)

Erwin, B. G., Persson, L. & Pegg, A. E., Jan 1 1984, In : Federation Proceedings. 43, 6, p. no. 1607

Research output: Contribution to journalArticle

Spermine
Antibodies
diamine N-acetyltransferase
1983
120 Citations (Scopus)

[23] Ornithine Decarboxylase (Mouse Kidney)

Seely, J. E. & Pegg, A., Jan 1 1983, In : Methods in Enzymology. 94, C, p. 158-161 4 p.

Research output: Contribution to journalArticle

Inbred Strains Mice
Ornithine Decarboxylase
Affinity Chromatography
Gel Chromatography
Kidney
12 Citations (Scopus)

Assay of Aminopropyltransferases

Pegg, A., Jan 1 1983, In : Methods in Enzymology. 94, C, p. 260-265 6 p.

Research output: Contribution to journalArticle

Spermidine Synthase
S-Adenosylmethionine
DEAE-Cellulose Chromatography
Decarboxylation
Transferases
12 Citations (Scopus)

Autoradiographic Localization of Ornithine Decarboxylase

Zagon, I., Seely, J. E. & Pegg, A., Jan 1 1983, In : Methods in Enzymology. 94, C, p. 169-176 8 p.

Research output: Contribution to journalArticle

Eflornithine
Ornithine
Ornithine Decarboxylase
Autoradiography
Kidney
91 Citations (Scopus)
Ornithine Decarboxylase
Radioimmunoassay
Kidney
Eflornithine
Enzymes
33 Citations (Scopus)

Comparison of inhibitors of S-adenosylmethionine decarboxylase from different species.

Pegg, A. E. & Jacobs, G., Aug 1 1983, In : The Biochemical journal. 213, 2, p. 495-502 8 p.

Research output: Contribution to journalArticle

Adenosylmethionine Decarboxylase
S-Adenosylmethionine
Mitoguazone
Yeast
Enzymes
1 Citation (Scopus)

Determination of Cellular Decarboxylated S-Adenosylmethionine Content

Pegg, A. E. & Bennett, R. A., Jan 1 1983, In : Methods in enzymology. 94, C, p. 69-72 4 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Decarboxylation
Putrescine
Spermidine
High Pressure Liquid Chromatography
49 Citations (Scopus)

Effect of 1,3-diaminopropane on ornithine decarboxylase enzyme protein in thioacetamide-treated rat liver

Seely, J. E. & Pegg, A. E., Jan 1 1983, In : Biochemical Journal. 216, 3, p. 701-707 7 p.

Research output: Contribution to journalArticle

Thioacetamide
Ornithine Decarboxylase
Liver
Rats
Enzyme activity
28 Citations (Scopus)
Carboxylesterase
5'-methylthioadenosine
13 Citations (Scopus)
Ethionine
Deoxyribonucleosides
Species Specificity
Nitrosamines
Alkylating Agents
15 Citations (Scopus)

Induction of spermidine N1-acetyltransferase by sodium N-butyrate and phytohemagglutinin in bovine lymphocytes

Matsui, I., Otani, S., Kuramoto, A., Morisawa, S. & Pegg, A. E., Jan 1 1983, In : Journal of Biochemistry. 93, 4, p. 961-966 6 p.

Research output: Contribution to journalArticle

Butyric Acid
Lymphocytes
Butyrates
Phytohemagglutinins
Sodium
7 Citations (Scopus)

Inhibition of Aminopropyltransferases

Pegg, A. E., Jan 1 1983, In : Methods in enzymology. 94, C, p. 294-297 4 p.

Research output: Contribution to journalArticle

Thionucleosides
Spermidine Synthase
S-Adenosylmethionine
Polyamines
Transferases
23 Citations (Scopus)

Inhibition of bacterial aminopropyltransferases by S-adenosyl-1,8-diamino-3-thiooctane and by dicyclohexylamine

Pegg, A. E., Bitonti, A. J., McCann, P. P. & Coward, J. K., May 8 1983, In : FEBS Letters. 155, 2, p. 192-196 5 p.

Research output: Contribution to journalArticle

Spermidine Synthase
Spermidine
Serratia marcescens
Microorganisms
Pseudomonas aeruginosa
27 Citations (Scopus)

Inhibitors of S-adenosylmethionine decarboxylase

Pegg, A., Jan 1 1983, In : Methods in Enzymology. 94, C, p. 239-247 9 p.

Research output: Contribution to journalArticle

Mitoguazone
Physarum
Adenosylmethionine Decarboxylase
S-Adenosylmethionine
Carboxy-Lyases
98 Citations (Scopus)

In vivo effects of α-dl-Difluoromethylornithine on the metabolism and morphology of Trypanosoma brucei brucei

Bacchi, C. J., Garofalo, J., Mockenhaupt, D., McCann, P. P., Diekema, K. A., Pegg, A. E., Nathan, H. C., Mullaney, E. A., Chunosoff, L., Sjoerdsma, A. & Hutner, S. H., Mar 1983, In : Molecular and biochemical parasitology. 7, 3, p. 209-225 17 p.

Research output: Contribution to journalArticle

Eflornithine
Trypanosoma brucei brucei
Parasites
Putrescine
Spermidine
8 Citations (Scopus)

Labeling and quantitation of ornithine decarboxylase protein by reaction with α-[5-14C]difluoromethylornithine

Seely, J. E., Pösö, H. & Pegg, A. E., Jan 1 1983, In : Methods in enzymology. 94, C, p. 206-209 4 p.

Research output: Contribution to journalArticle

Eflornithine
Ornithine
Ornithine Decarboxylase
Kidney
Proteins
5 Citations (Scopus)
Eflornithine
Saccharomyces
Ornithine Decarboxylase
Yeast
Saccharomyces cerevisiae