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1965 …2018
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Research Output 1965 2018

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Article
1981
37 Citations (Scopus)

Specificity of mammalian spermidine synthase and spermine synthase

Pegg, A. E., Shuttleworth, K. & Hibasami, H., Jan 1 1981, In : Biochemical Journal. 197, 2, p. 315-320 6 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)

Stimulation of transfer of methyl groups from O6-methylguanine in DNA to protein by rat liver extracts in response to hepatotoxins

Pegg, A. E. & Perry, W., Dec 1 1981, In : Carcinogenesis. 2, 11, p. 1195-1200 6 p.

Research output: Contribution to journalArticle

Liver Extracts
1,2-Dimethylhydrazine
Methylnitrosourea
Dimethylnitrosamine
Diethylnitrosamine
19 Citations (Scopus)

Uptake of putrescine by 3T3 and SV3T3 cells and its effect on ornithine decarboxylase activity

Bethell, D. R. & Pegg, A. E., Dec 1981, In : Journal of Cellular Physiology. 109, 3, p. 461-468 8 p.

Research output: Contribution to journalArticle

3T3 Cells
Ornithine Decarboxylase
Putrescine
Cadaverine
Growth
1980
16 Citations (Scopus)

Alkylation of dna and carcinogenicity of w-nitroso compounds

Montesano, R., Pegg, A. E. & Margison, G. P., Jan 1 1980, In : Journal of Toxicology and Environmental Health. 6, 5-6, p. 81-88 8 p.

Research output: Contribution to journalArticle

Nitroso Compounds
Alkylation
DNA
Nitrosamines
Alkylating Agents
36 Citations (Scopus)

Decarboxylated S-adenosylmethionine in mammalian cells.

Hibasami, H., Hoffman, J. L. & Pegg, A., Jul 25 1980, In : Journal of Biological Chemistry. 255, 14, p. 6675-6678 4 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Cells
Electrophoresis
Methionine
Labeling
6 Citations (Scopus)

DNA damage and repair in mammalian cells.

Williams, G. M., Bordet, C., Cerutti, P. A., Fuchs, R. P., Laval, J., Lu, S. H., Parodi, S., Pegg, A. & Rajewsky, M. F., Dec 1 1980, In : IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Supplement. 2 Suppl, p. 201-226 26 p.

Research output: Contribution to journalArticle

Preclinical Drug Evaluations
DNA Repair
Cricetinae
Carcinogens
DNA Damage
102 Citations (Scopus)

Effect of Chronic Treatment of Rats with Dimethylnitrosamine on the Removal of O6-Methylguanine from DNA

Montesano, R., Bresil, H., Planche-Martel, G., Margiaon, G. P. & Pegg, A., Feb 1 1980, In : Cancer Research. 40, 2, p. 452-458 7 p.

Research output: Contribution to journalArticle

Dimethylnitrosamine
DNA
Liver
Kidney
Enzymes
89 Citations (Scopus)
Thioacetamide
Hepatectomy
Liver
Cytosol
Growth Hormone
17 Citations (Scopus)

Effects of glucocorticoids on peptide chain initiation in heart and skeletal muscle.

Rannels, D. E., Rannels, S. R., Li, J. B., Pegg, A., Morgan, H. E. & Jefferson, L. J., Jan 1 1980, In : Advances in myocardiology. 1, p. 493-501 9 p.

Research output: Contribution to journalArticle

Glucocorticoids
Myocardium
Skeletal Muscle
Peptide Initiation Factors
RNA
14 Citations (Scopus)

Effects of growth hormone and glucagon on ornithine decarboxylase activity and adenosine 3‘,5‘-Monophosphate levels in isolated rat hepatocytes

Klingensmith, M. R., Freifeld, A. G., Pegg, A. E. & Jefferson, L. S., Jan 1980, In : Endocrinology. 106, 1, p. 125-132 8 p.

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Glucagon
Adenosine
Growth Hormone
Hepatocytes
21 Citations (Scopus)

Formation and subsequent repair of alkylation lesions in tissues of rodents treated with nitrosamines

Pegg, A. E., Jan 1 1980, In : Archives of Toxicology. 45, SUPPL.3, p. 55-68 14 p.

Research output: Contribution to journalArticle

Nitrosamines
Alkylation
Rodentia
90 Citations (Scopus)
Liver Extracts
Acetylation
Spermidine
Carbon Tetrachloride
Rats
5 Citations (Scopus)
Spermidine Synthase
Guanidines
Mitoguazone
S-Adenosylmethionine
Polyamines
44 Citations (Scopus)

Polyamine metabolism during cardiac hypertrophy

Pegg, A. E. & Hibasami, H., Jan 1 1980, In : American Journal of Physiology - Endocrinology and Metabolism. 2, 5, p. E372-E378

Research output: Contribution to journalArticle

Putrescine
Polyamines
Cardiomegaly
Adenosylmethionine Decarboxylase
Thyroxine
55 Citations (Scopus)

Specific and potent inhibition of spermidine synthase by the transition-state analog, S-adenosyl-3-thio-1,8-diaminooctane

Tang, K. C., Pegg, A. & Coward, J. K., Jan 1 1980, In : Topics in Catalysis. 96, 3, p. 1371-1377 7 p.

Research output: Contribution to journalArticle

Spermidine Synthase
Enzymes
Enzyme inhibition
Spermine Synthase
Transferases
84 Citations (Scopus)

Studies of inhibition of rat spermidine synthase and spermine synthase.

Hibasami, H., Borchardt, R. T., Chen, S. Y., Coward, J. K. & Pegg, A. E., May 1 1980, In : The Biochemical journal. 187, 2, p. 419-428 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The dual action of the non-physiological diamines 1,3 diaminopropane and cadaverine on ornithine decarboxylase of HTC cells

McCann, P. P., Tardif, C., Pegg, A. E. & Diekema, K., Jun 9 1980, In : Life Sciences. 26, 23, p. 2003-2010 8 p.

Research output: Contribution to journalArticle

Cadaverine
Ornithine Decarboxylase
Diamines
Putrescine
Cell Extracts
1979
83 Citations (Scopus)

Decarboxylation of ornithine and lysine in rat tissues

Pegg, A. E. & McGill, S., Jun 6 1979, In : BBA - Enzymology. 568, 2, p. 416-427 12 p.

Research output: Contribution to journalArticle

lysine decarboxylase
Decarboxylation
Ornithine
Ornithine Decarboxylase
Lysine
43 Citations (Scopus)

Effects of diamines on ornithine decarboxylase activity in control and virally transformed mouse fibroblasts.

Bethell, D. R. & Pegg, A. E., Apr 15 1979, In : The Biochemical journal. 180, 1, p. 87-94 8 p.

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Diamines
Fibroblasts
3T3 Cells
Propane
15 Citations (Scopus)

Enhancement of Biochemical Transformation of Mammalian Cells by Herpes Simplex Virus Following Nitrosomethylurea Treatment

Howett, M. K., Pegg, A. E. & Rapp, F., Mar 1 1979, In : Cancer Research. 39, 3, p. 1041-1045 5 p.

Research output: Contribution to journalArticle

Methylnitrosourea
Simplexvirus
Carcinogens
Virus Diseases
DNA Repair
38 Citations (Scopus)

Formation and Loss of Alkylated Purines from DNA of Hamster Liver after Administration of Dimethylnitrosamine

Stumpf, R., Margison, G. P., Montesano, R. & Pegg, A. E., Jan 1 1979, In : Cancer Research. 39, 1, p. 50-54 5 p.

Research output: Contribution to journalArticle

Dimethylnitrosamine
Purines
Cricetinae
Liver
DNA
44 Citations (Scopus)
Diethylnitrosamine
Liver
DNA
Alkylation
Ethylnitrosourea
9 Citations (Scopus)

Inhibition of cytomegalovirus-stimulated human cell ornithine decarboxylase by α-difluoromethylornithine

Isom, H. C. & Pegg, A. E., Oct 25 1979, In : BBA Section Nucleic Acids And Protein Synthesis. 564, 3, p. 402-413 12 p.

Research output: Contribution to journalArticle

Eflornithine
Ornithine Decarboxylase
Cytomegalovirus
DNA
Putrescine

Inhibition of ornithine decarboxylase activity by diamines in control and transformed fibroblasts

Bethell, D. R. & Pegg, A., Jan 1 1979, In : Federation Proceedings. 38, 3 I

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Diamines
Fibroblasts
38 Citations (Scopus)

Investigation of the turnover of rat liver S-adenosylmethionine decarboxylase using a specific antibody

Pegg, A., Jan 1 1979, In : Journal of Biological Chemistry. 254, 9, p. 3249-3253 5 p.

Research output: Contribution to journalArticle

Adenosylmethionine Decarboxylase
Antigen-antibody reactions
Antigen-Antibody Reactions
Liver Regeneration
Carboxy-Lyases
24 Citations (Scopus)

Metabolism of O6-alkyldeoxyguanosines and their effect on removal of O6-methylguanine from rat liver DNA

Pegg, A. & Swann, P. F., Dec 17 1979, In : BBA Section Nucleic Acids And Protein Synthesis. 565, 2, p. 241-252 12 p.

Research output: Contribution to journalArticle

Liver Extracts
Adenosine Deaminase
Liver
DNA
Adenosine
12 Citations (Scopus)

The decarboxylation of S-adenosylmethionine by detergent-treated extracts of rat liver.

Wilson, J., Corti, A., Hawkins, M., Williams-Ashman, H. G. & Pegg, A. E., Jun 15 1979, In : The Biochemical journal. 180, 3, p. 515-522 8 p.

Research output: Contribution to journalArticle

Adenosylmethionine Decarboxylase
Homoserine
S-Adenosylmethionine
Tissue Extracts
Carbon Dioxide
1978
1 Citation (Scopus)
30 Citations (Scopus)

Differential inhibition of mammalian aminopropyltransferase activities

Hibasami, H. & Pegg, A., Apr 28 1978, In : Biochemical and Biophysical Research Communications. 81, 4, p. 1398-1405 8 p.

Research output: Contribution to journalArticle

Spermidine Synthase
Diamines
Spermine Synthase
S-Adenosylhomocysteine
Spermidine

Effect of glucocorticoids on peptide-chain initiation in heart and skeletal muscle

Rannels, D. E., Rannels, S. R., Pegg, A. & Jefferson, L. J., Jan 1 1978, In : Journal of Molecular and Cellular Cardiology. 10, SUPPL.1, 1 p.

Research output: Contribution to journalArticle

Glucocorticoids
Myocardium
Skeletal Muscle
Peptides
8 Citations (Scopus)
Dimethylnitrosamine
Hypophysectomy
Purines
Liver
DNA
11 Citations (Scopus)
Dimethylnitrosamine
Diethylnitrosamine
Liver
DNA
dibutylnitrosamine
34 Citations (Scopus)

Effect of starvation on initiation of protein synthesis in skeletal muscle and heart.

Rannels, D. E., Pegg, A., Rannels, S. R. & Jefferson, L. J., Aug 1978, In : The American journal of physiology. 235, 2

Research output: Contribution to journalArticle

Starvation
Skeletal Muscle
Peptides
RNA
Psoas Muscles
48 Citations (Scopus)

Effects of aliphatic diamines on rat liver ornithine decarboxylase activity

Pegg, A. E., Conover, C. & Wrona, A., Jan 1 1978, In : Biochemical Journal. 170, 3, p. 651-660 10 p.

Research output: Contribution to journalArticle

Ornithine Decarboxylase
Diamines
Liver
Rats
Putrescine
30 Citations (Scopus)
Adenosylmethionine Decarboxylase
Ornithine Decarboxylase
Hepatectomy
Spermidine
Liver
1 Citation (Scopus)
Dimethylnitrosamine
DNA
In Vitro Techniques
O-(6)-methylguanine
81 Citations (Scopus)

Enzymatic removal of O6-methylguanine from DNA by mammalian cell extracts

Pegg, A., Sep 14 1978, In : Biochemical and Biophysical Research Communications. 84, 1, p. 166-173 8 p.

Research output: Contribution to journalArticle

Cell Extracts
Cells
Liver Extracts
DNA
Glycoside Hydrolases
97 Citations (Scopus)
Dimethylnitrosamine
Kidney
Liver
DNA
O-(6)-methylguanine
79 Citations (Scopus)
Glucocorticoids
Skeletal Muscle
RNA
Peptides
Peptide Initiation Factors
42 Citations (Scopus)
Amine Oxidase (Copper-Containing)
Mitoguazone
Spermidine
Putrescine
Propylamines
26 Citations (Scopus)
Guanidines
Mitoguazone
Adenosylmethionine Decarboxylase
Carboxy-Lyases
Structure-Activity Relationship
14 Citations (Scopus)
Aminoacetonitrile
1,2-Dimethylhydrazine
Level control
Alkylation
Metabolism
33 Citations (Scopus)

Rapid and convenient method for the assay of aminopropyltransferases

Hibasami, H. & Pegg, A. E., Jan 1 1978, In : Biochemical Journal. 169, 3, p. 709-712 4 p.

Research output: Contribution to journalArticle

Spermidine Synthase
Amines
Assays
Cadaverine
Propane
40 Citations (Scopus)

Removal of Methylated Purines from Rat Liver DNA after Administration of Dimethylnitrosamine

Pegg, A. & Hui, G., Jan 1 1978, In : Cancer Research. 38, 7, p. 2011-2017 7 p.

Research output: Contribution to journalArticle

Dimethylnitrosamine
Purines
Liver
DNA
Chromatin
nitroso compounds
Nitroso Compounds
carcinogenicity
DNA
1977
101 Citations (Scopus)
Dimethylnitrosamine
Alkylation
Liver
DNA
Guanine

Differential effects of glucocorticoids on initiation of protein synthesis in skeletal muscle and heart

Rannels, S. R., Rannels, D. E., Pegg, A. E. & Jefferson, L. S., Jan 1 1977, In : Federation Proceedings. 36, 3, p. No. 1651

Research output: Contribution to journalArticle

Glucocorticoids
Skeletal Muscle
Proteins
38 Citations (Scopus)

Evidence for the presence of pyruvate in rat liver S-adenosylmethionine decarboxylase

Pegg, A. E., Dec 1 1977, In : FEBS Letters. 84, 1, p. 33-36 4 p.

Research output: Contribution to journalArticle

Pyruvates
Adenosylmethionine Decarboxylase
Carboxy-Lyases
Coenzymes
Pyruvic Acid
1,2-Dimethylhydrazine
Dimethylnitrosamine
Liver
DNA
O-(6)-methylguanine
307 Citations (Scopus)
Nitroso Compounds
Alkylating Agents
Nucleosides
Nucleic Acids
Carcinogenesis