Ashley Lorel Chan

    • 238 Citations
    • 4 h-Index
    20122015

    Research output per year

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    Research Output

    • 238 Citations
    • 4 h-Index
    • 4 Article
    2015

    Potential mechanisms for cancer resistance in elephants and comparative cellular response to DNA Damage in Humans

    Abegglen, L. M., Caulin, A. F., Chan, A., Lee, K., Robinson, R., Campbell, M. S., Kiso, W. K., Schmitt, D. L., Waddell, P. J., Bhaskara, S., Jensen, S. T., Maley, C. C. & Schiffman, J. D., Nov 3 2015, In : JAMA - Journal of the American Medical Association. 314, 17, p. 1850-1860 11 p.

    Research output: Contribution to journalArticle

    147 Scopus citations

    Synthesis and biological evaluation of pyrazolo[1,5- A ]pyrimidine compounds as potent and selective pim-1 inhibitors

    Xu, Y., Brenning, B. G., Kultgen, S. G., Foulks, J. M., Clifford, A., Lai, S., Chan, A., Merx, S., McCullar, M. V., Kanner, S. B. & Ho, K. K., Jan 8 2015, In : ACS Medicinal Chemistry Letters. 6, 1, p. 63-67 5 p.

    Research output: Contribution to journalArticle

    28 Scopus citations
    2014

    A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas

    Foulks, J. M., Carpenter, K. J., Luo, B., Xu, Y., Senina, A., Nix, R., Chan, A., Clifford, A., Wilkes, M., Vollmer, D., Brenning, B., Merx, S., Lai, S., McCullar, M. V., Ho, K. K., Albertson, D. J., Call, L. T., Bearss, J. J., Tripp, S., Liu, T. & 5 others, Stephens, B. J., Mollard, A., Warner, S. L., Bearss, D. J. & Kanner, S. B., Jan 1 2014, In : Neoplasia. 16, 5, p. 403-412 10 p.

    Research output: Contribution to journalArticle

    38 Scopus citations
    2012

    Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors

    Kumar, D. V., Hoarau, C., Bursavich, M., Slattum, P., Gerrish, D., Yager, K., Saunders, M., Shenderovich, M., Roth, B. L., McKinnon, R., Chan, A., Cimbora, D. M., Bradford, C., Reeves, L., Patton, S., Papac, D. I., Williams, B. L. & Carlson, R. O., Jul 1 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 13, p. 4377-4385 9 p.

    Research output: Contribution to journalArticle

    23 Scopus citations