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Bernhard Luscher, PhD

    • 6262 Citations
    • 35 h-Index
    1985 …2020
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    • 7 Similar Profiles
    GABA-A Receptors Medicine & Life Sciences
    Synapses Medicine & Life Sciences
    Neurons Medicine & Life Sciences
    Lipoylation Medicine & Life Sciences
    Aminobutyrates Medicine & Life Sciences
    Cluster Analysis Medicine & Life Sciences
    gamma-Aminobutyric Acid Medicine & Life Sciences
    Brain Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects 1999 2020

    GABAergic Control of Depression Related Brain States

    Luscher, B.

    National Institutes of Health

    4/18/13 → 8/31/20

    Project: Research project

    Major Depressive Disorder
    Interneurons
    Depression
    Brain
    Antidepressive Agents

    A novel developmental mouse model of major depressive disorder

    Luscher, B.

    National Institutes of Health

    5/24/12 → 4/30/15

    Project: Research project

    Major Depressive Disorder
    Diazepam
    Anxiety
    Pharmacology
    Phenotype

    Use of a mouse model of anxious depression to assess the safety of pediatric anti

    Luscher, B.

    National Institutes of Health

    9/30/09 → 8/31/12

    Project: Research project

    Depression
    Pediatrics
    Antidepressive Agents
    Safety
    Anti-Anxiety Agents

    Clustering and Synaptic Targeting of GABA-A Receptors

    Luscher, B.

    National Institutes of Health

    12/1/00 → 7/9/10

    Project: Research project

    Aminobutyrates
    GABA-A Receptors
    Cluster Analysis
    Synapses
    Synaptic Transmission

    Mapping the Neural Substrate of Anxiety

    Luscher, B.

    National Institutes of Health

    12/1/99 → 4/30/11

    Project: Research project

    Anxiety
    GABA-A Receptors
    Anxiety Disorders
    Neurogenesis
    Brain

    Research Output 1985 2019

    4 Citations (Scopus)

    Brexanolone, a neurosteroid antidepressant, vindicates the gabaergic deficit hypothesis of depression and may foster resilience [version 1; peer review: 4 approved]

    Lüscher, B. & Möhler, H., Jan 1 2019, In : F1000Research. 8, 751.

    Research output: Contribution to journal › Review article

    Open Access
    Pregnanolone
    Peer Review
    Antidepressive Agents
    Neurotransmitter Agents
    Depression

    Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels

    Wu, Z., Huo, Q., Ren, L., Dong, F., Feng, M., Wang, Y., Bai, Y., Luscher, B., Li, S. T., Wang, G. L., Long, C., Wang, Y., Wu, G. & Chen, G., May 15 2019, In : Molecular Brain. 12, 1, 50.

    Research output: Contribution to journal › Article

    Open Access
    Seizures
    Brain
    Newborn Animals
    Knockout Mice
    Anticonvulsants

    Ketamine normalizes binge drinking-induced defects in glutamatergic synaptic transmission and ethanol drinking behavior in female but not male mice

    Crowley, N., Magee, S. N., Feng, M., Jefferson, S. J., Morris, C. J., Dao, N. C., Brockway, D. F. & Luscher, B., May 1 2019, In : Neuropharmacology. 149, p. 35-44 10 p.

    Research output: Contribution to journal › Article

    Binge Drinking
    Drinking Behavior
    Ketamine
    Synaptic Transmission
    Drinking

    Reversal of a Treatment-Resistant, Depression-Related Brain State with the Kv7 Channel Opener Retigabine

    Feng, M., Crowley, N. A., Patel, A., Guo, Y., Bugni, S. E. & Luscher, B., May 15 2019, In : Neuroscience. 406, p. 109-125 17 p.

    Research output: Contribution to journal › Article

    Treatment-Resistant Depressive Disorder
    High Fat Diet
    Desipramine
    Pyramidal Cells
    Fluoxetine
    7 Citations (Scopus)

    Adolescent Social Stress Increases Anxiety-like Behavior and Alters Synaptic Transmission, Without Influencing Nicotine Responses, in a Sex-Dependent Manner

    Caruso, M. J., Crowley, N., Reiss, D. E., Caulfield, J. I., Luscher, B., Cavigelli, S. A. & Kamens, H. M., Mar 1 2018, In : Neuroscience. 373, p. 182-198 17 p.

    Research output: Contribution to journal › Article

    Nicotine
    Synaptic Transmission
    Nucleus Accumbens
    Anxiety
    Prefrontal Cortex