• 2361 Citations
  • 19 h-Index
19932018
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Research Output 1993 2018

  • 2361 Citations
  • 19 h-Index
  • 28 Article
  • 1 Comment/debate
  • 1 Review article
2018

Mexiletine rescues a mixed biophysical phenotype of the cardiac sodium channel arising from the SCN5a mutation, N406K, found in LQT3 patients

Hu, R. M., Tester, D. J., Li, R., Sun, T., Peterson, B. Z., Ackerman, M. J., Makielski, J. C. & Tan, B. H., Jan 1 2018, In : Channels. 12, 1, p. 176-186 11 p.

Research output: Contribution to journalArticle

Mexiletine
Sodium Channels
Phenotype
Mutation
Torsades de Pointes
2015
11 Citations (Scopus)

Arrhythmogenic biophysical phenotype for SCN5A mutation S1787N depends upon splice variant background and intracellular acidosis

Hu, R. M., Tan, B. H., Tester, D. J., Song, C., He, Y., Dovat, S., Peterson, B. Z., Ackerman, M. J. & Makielski, J. C., Apr 29 2015, In : PloS one. 10, 4, e0124921.

Research output: Contribution to journalArticle

acidosis
Acidosis
Protein Isoforms
Phenotype
mutation
8 Citations (Scopus)

Regulation of L-type calcium channel by phospholemman in cardiac myocytes

Zhang, X. Q., Wang, J. F., Song, J., Rabinowitz, J., Chen, X., Houser, S. R., Peterson, B. Z., Tucker, A. L., Feldman, A. M. & Cheung, J. Y., Jul 1 2015, In : Journal of Molecular and Cellular Cardiology. 84, p. 104-111 8 p.

Research output: Contribution to journalArticle

L-Type Calcium Channels
Cardiac Myocytes
Muscle Cells
Green Fluorescent Proteins
phospholemman
2013
1 Citation (Scopus)

Amino acid substitutions in the pore affect the anomalous mole fraction effect of CaV1.2 channels

Li, Z., Huang, H., Yang, B., Jiang, H., Gao, G. F., Peterson, B. & Huang, C. X., Feb 1 2013, In : Molecular medicine reports. 7, 2, p. 571-576 6 p.

Research output: Contribution to journalArticle

Divalent Cations
Amino Acid Substitution
Glycine
Lysine
Substitution reactions
2012
21 Citations (Scopus)

Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: Potential involvement of Na +/Ca 2+ exchanger

Song, J., Gao, E., Wang, J., Zhang, X. Q., Chan, T. O., Koch, W. J., Shang, X., Joseph, J. I., Peterson, B. Z., Feldman, A. M. & Cheung, J. Y., Feb 1 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 302, 3, p. H770-H781

Research output: Contribution to journalArticle

Sodium-Calcium Exchanger
Muscle Cells
Cardiac Arrhythmias
Heart Failure
Mortality
5 Citations (Scopus)

Domain III regulates N-type (Ca V2.2) calcium channel closing kinetics

Yarotskyy, V., Gao, G., Peterson, B. Z. & Elmslie, K. S., Apr 1 2012, In : Journal of neurophysiology. 107, 7, p. 1942-1951 10 p.

Research output: Contribution to journalArticle

Calcium Channels
L-Type Calcium Channels
Pharmacology
Membranes
roscovitine
2011
9 Citations (Scopus)

Genetic Variants and Monoallelic Expression of Surfactant Protein-D in Inflammatory Bowel Disease

Lin, Z., John, G., Hegarty, J. P., Berg, A., Yu, W., Wang, Y., Kelly, A. A., Peterson, B., Poritz, L., Floros, J. & Koltun, W., Sep 1 2011, In : Annals of Human Genetics. 75, 5, p. 559-568 10 p.

Research output: Contribution to journalArticle

Pulmonary Surfactant-Associated Protein D
Ulcerative Colitis
Inflammatory Bowel Diseases
Crohn Disease
Single Nucleotide Polymorphism
51 Citations (Scopus)

Identification of disease-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease

Lin, Z., Hegarty, J., Cappel, J., Yu, W., Chen, X., Faber, P., Wang, Y., Kelly, A., Poritz, L., Peterson, B., Schreiber, S., Fan, J. B. & Koltun, W., Jul 1 2011, In : Clinical Genetics. 80, 1, p. 59-67 9 p.

Research output: Contribution to journalArticle

DNA Methylation
Inflammatory Bowel Diseases
Ulcerative Colitis
Crohn Disease
Methylation
2010
10 Citations (Scopus)

Amino acid substitutions in the FXYD motif enhance phospholemman-induced modulation of cardiac L-type calcium channels

Guo, K., Wang, X., Gao, G., Huang, C., Elmslie, K. S. & Peterson, B. Z., Nov 1 2010, In : American Journal of Physiology - Cell Physiology. 299, 5, p. C1203-C1211

Research output: Contribution to journalArticle

L-Type Calcium Channels
Amino Acid Substitution
Calcium Channels
Cysteine
phospholemman
7 Citations (Scopus)

A single amino acid change in CaV1.2 channels eliminates the permeation and gating differences between Ca2+ and Ba2+

Li, Z., Wang, X., Gao, G., Qu, D., Yu, B., Huang, C., Elmslie, K. S. & Peterson, B. Z., Feb 1 2010, In : Journal of Membrane Biology. 233, 1-3, p. 23-33 11 p.

Research output: Contribution to journalArticle

Monovalent Cations
Mutagenesis
Glutamic Acid
Ions
Amino Acids
23 Citations (Scopus)

Phospholemman modulates the gating of cardiac L-type calcium channels

Wang, X., Gao, G., Guo, K., Yarotskyy, V., Huang, C., Elmslie, K. S. & Peterson, B. Z., Apr 7 2010, In : Biophysical journal. 98, 7, p. 1149-1159 11 p.

Research output: Contribution to journalArticle

L-Type Calcium Channels
Action Potentials
HEK293 Cells
Ion Transport
Cardiac Myocytes
19 Citations (Scopus)

Roscovitine binds to novel L-channel (Cav1.2) sites that separately affect activation and inactivation

Yarotskyy, V., Gao, G., Du, L., Ganapathi, S. B., Peterson, B. Z. & Elmslie, K. S., Jan 1 2010, In : Journal of Biological Chemistry. 285, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

Chemical activation
Calcium Channel Blockers
Torsades de Pointes
L-Type Calcium Channels
Purines
2009
58 Citations (Scopus)

The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: Multiple altered gating mechanisms and pharmacological restoration of inactivation

Yarotskyy, V., Gao, G., Peterson, B. & Elmslie, K. S., Feb 12 2009, In : Journal of Physiology. 587, 3, p. 551-565 15 p.

Research output: Contribution to journalArticle

Pharmacology
Mutation
Cardiac Arrhythmias
Timothy syndrome
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
47 Citations (Scopus)
PAR-2 Receptor
Unmyelinated Nerve Fibers
Mast Cells
Esophagus
Hypersensitivity
2007
13 Citations (Scopus)

Calcicludine binding to the outer pore of L-type calcium channels is allosterically coupled to dihydropyridine binding

Wang, X., Du, L. & Peterson, B. Z., Jun 26 2007, In : Biochemistry. 46, 25, p. 7590-7598 9 p.

Research output: Contribution to journalArticle

L-Type Calcium Channels
Dihydropyridines
Electrophysiology
Acidic Amino Acids
Elapidae
2006
27 Citations (Scopus)
Dihydropyridines
Calcium Channels
Ions
Excitation Contraction Coupling
L-Type Calcium Channels
84 Citations (Scopus)

Regulation of the transient receptor potential channel TRPM2 by the Ca 2+ sensor calmodulin

Tong, Q., Zhang, W., Conrad, K., Mostoller, K., Cheung, J. Y., Peterson, B. Z. & Miller, B. A., Apr 7 2006, In : Journal of Biological Chemistry. 281, 14, p. 9076-9085 10 p.

Research output: Contribution to journalArticle

Transient Receptor Potential Channels
Calmodulin
Sensors
Chemical activation
Immunoprecipitation
2005
17 Citations (Scopus)

Amino acid substitutions in the pore of the CaV1.2 calcium channel reduce barium currents without affecting calcium currents

Wang, X., Ponoran, T. A., Rasmusson, R. L., Ragsdale, D. S. & Peterson, B. Z., Sep 2005, In : Biophysical journal. 89, 3, p. 1731-1743 13 p.

Research output: Contribution to journalArticle

Amino Acid Substitution
Barium
Ions
Calcium
Lysine
2001
337 Citations (Scopus)

Preassociation of calmodulin with voltage-gated Ca2+ channels revealed by FRET in single living cells

Erickson, M. G., Alseikhan, B. A., Peterson, B. Z. & Yue, D. T., Sep 27 2001, In : Neuron. 31, 6, p. 973-985 13 p.

Research output: Contribution to journalArticle

Calmodulin
Fluorescence Resonance Energy Transfer
Proteins
2000
78 Citations (Scopus)

Ca2+ channel modulation by recombinant auxiliary β subunits expressed in young adult heart cells

Wei, S. K., Colecraft, H. M., DeMaria, C. D., Peterson, B., Zhang, R., Kohout, T. A., Rogers, T. B. & Yue, D. T., Jan 1 2000, In : Circulation Research. 86, 2, p. 175-184 10 p.

Research output: Contribution to journalArticle

Young Adult
Green Fluorescent Proteins
Protein Subunits
Muscle Cells
Plasmids
166 Citations (Scopus)

Critical determinants of Ca2+-dependent inactivation within an EF-hand motif of L-type Ca2+ channels

Peterson, B. Z., Lee, J. S., Mulle, J. G., Wang, V., De Leon, M. & Yue, D. T., Apr 2000, In : Biophysical journal. 78, 4, p. 1906-1920 15 p.

Research output: Contribution to journalArticle

EF Hand Motifs
Amino Acids
L-Type Calcium Channels
Valine
Calmodulin
1999
652 Citations (Scopus)

Calmodulin is the Ca2+ sensor for Ca2+-dependent inactivation of L- type calcium channels

Peterson, B. Z., DeMaria, C. D. & Yue, D. T., Mar 1999, In : Neuron. 22, 3, p. 549-558 10 p.

Research output: Contribution to journalArticle

R-Type Calcium Channels
Q-Type Calcium Channels
L-Type Calcium Channels
Calmodulin
Calcium Channels
1 Citation (Scopus)

Erratum: Calmodulin is the Ca2+ sensor for Ca2+-dependent inactivation of L-type calcium channels (Neuron (March 1999))

Peterson, B., Demaria, C. D., Adelman, J. P. & Yue, D. T., Jan 1 1999, In : Neuron. 22, 4, 1 p.

Research output: Contribution to journalComment/debate

L-Type Calcium Channels
Calmodulin
Neurons
1997
86 Citations (Scopus)

Analysis of the dihydropyridine receptor site of L-type calcium channels by alanine-scanning mutagenesis

Peterson, B. Z., Johnson, B. D., Hockerman, G. H., Acheson, M., Scheuer, T. & Catterall, W. A., Aug 12 1997, In : Journal of Biological Chemistry. 272, 30, p. 18752-18758 7 p.

Research output: Contribution to journalArticle

L-Type Calcium Channels
Mutagenesis
Alanine
Scanning
Amino Acids
73 Citations (Scopus)

Construction of a high-affinity receptor site for dihydropyridine agonists and antagonists by single amino acid substitutions in a non-L-type Ca2+ channel

Hockerman, G. H., Peterson, B. Z., Sharp, E., Tanada, T. N., Scheuer, T. & Catterall, W. A., Dec 23 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 26, p. 14906-14911 6 p.

Research output: Contribution to journalArticle

L-Type Calcium Channels
Amino Acid Substitution
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
S 6
1,4-dihydropyridine
77 Citations (Scopus)

Modulation of the cloned skeletal muscle L-type Ca2+ channel by anchored cAMP-dependent protein kinase

Johnson, B. D., Brousal, J. P., Peterson, B., Gallombardo, P. A., Hockerman, G. H., Lai, Y., Scheuer, T. & Catterall, W. A., Feb 21 1997, In : Journal of Neuroscience. 17, 4, p. 1243-1255 13 p.

Research output: Contribution to journalArticle

Cyclic AMP-Dependent Protein Kinases
Skeletal Muscle
Protein Kinases
Muscle Cells
Phosphorylation
287 Citations (Scopus)

Molecular determinants of drug binding ad action on L-type calcium channels

Hockerman, G. H., Peterson, B., Johnson, B. D. & Catterall, W. A., Jun 19 1997, In : Annual Review of Pharmacology and Toxicology. 37, p. 361-396 36 p.

Research output: Contribution to journalReview article

Dihydropyridines
L-Type Calcium Channels
Azepines
Amino Acids
Pharmaceutical Preparations
1996
100 Citations (Scopus)

Molecular determinants of high affinity dihydropyridine binding in L-type calcium channels

Peterson, B. Z., Tanada, T. N. & Catterall, W. A., Mar 8 1996, In : Journal of Biological Chemistry. 271, 10, p. 5293-5296 4 p.

Research output: Contribution to journalArticle

L-Type Calcium Channels
Mutation
Amino Acids
Mutagenesis
Tyrosine
1995
74 Citations (Scopus)

Calcium binding in the pore of L-type calcium channels modulates high affinity dihydropyridine binding

Peterson, B. & Catterall, W. A., Aug 4 1995, In : Journal of Biological Chemistry. 270, 31, p. 18201-18204 4 p.

Research output: Contribution to journalArticle

L-Type Calcium Channels
Calcium
Mutation
Skeletal Muscle
Linings
1993
19 Citations (Scopus)

Selective Dephosphorylation of the Subunits of Skeletal Muscle Calcium Channels by Purified Phosphoprotein Phosphatases

Lai, Y., Peterson, B. Z. & Catterall, W. A., Oct 1993, In : Journal of neurochemistry. 61, 4, p. 1333-1339 7 p.

Research output: Contribution to journalArticle

Phosphoprotein Phosphatases
Phosphopeptides
Calcium Channels
Muscle
Skeletal Muscle