• 10084 Citations
  • 57 h-Index
1995 …2023
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1995 2020

2017
5 Citations (Scopus)

The RicAFT (YmcA-YlbF-YaaT) complex carries two [4Fe-4S]2+ clusters and may respond to redox changes

Tanner, A. W., Carabetta, V. J., Martinie, R. J., Mashruwala, A. A., Boyd, J. M., Krebs, C. & Dubnau, D., Jun 1 2017, In : Molecular Microbiology. 104, 5, p. 837-850 14 p.

Research output: Contribution to journalArticle

Oxidation-Reduction
Iron-Sulfur Proteins
Proteins
Flavin-Adenine Dinucleotide
Biofilms
6 Citations (Scopus)

Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes

Martinie, R. J., Pollock, C. J., Matthews, M. L., Bollinger, Jr., J. M., Krebs, C. & Silakov, A., Nov 6 2017, In : Inorganic Chemistry. 56, 21, p. 13382-13389 8 p.

Research output: Contribution to journalArticle

Vanadates
enzymes
Iron
iron
Substrates
29 Citations (Scopus)

Visualizing the reaction cycle in an Iron(II)- and 2-(Oxo)-glutarate-dependent hydroxylase

Mitchell, A. J., Dunham, N. P., Martinie, R. J., Bergman, J. A., Pollock, C. J., Hu, K., Allen, B. D., Chang, W. C., Silakov, A., Bollinger, Jr., J. M., Krebs, C. & Boal, A. K., Jan 1 2017, In : Journal of the American Chemical Society. 139, 39, p. 13830-13836 7 p.

Research output: Contribution to journalArticle

Glutarates
Oxygenases
Vanadium
Mixed Function Oxygenases
Arginine
2018
8 Citations (Scopus)

Installation of the Ether Bridge of Lolines by the Iron- and 2-Oxoglutarate-Dependent Oxygenase, LolO: Regio- and Stereochemistry of Sequential Hydroxylation and Oxacyclization Reactions

Pan, J., Bhardwaj, M., Zhang, B., Chang, W. C., Schardl, C. L., Krebs, C., Grossman, R. B. & Martin Bollinger, J., Apr 10 2018, In : Biochemistry. 57, 14, p. 2074-2083 10 p.

Research output: Contribution to journalArticle

Oxygenases
Hydroxylation
Stereochemistry
Ether
Iron
8 Citations (Scopus)

Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosinederived dihydroxyphenylalanine radical

Blaesi, E. J., Palowitch, G. M., Hu, K., Kim, A. J., Rose, H. R., Alapati, R., Lougee, M. G., Kim, H. J., Taguchi, A. T., Tan, K. O., Laremore, T. N., Griffin, R. G., Krebs, C., Matthews, M. L., Silakov, A., Bollinger, J. M., Allen, B. D. & Boal, A. K., Oct 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. 10022-10027 6 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Dihydroxyphenylalanine
Catalysis
Metals
Tissue Plasminogen Activator
9 Citations (Scopus)

Non-Heme Diiron Model Complexes Can Mediate Direct NO Reduction: Mechanistic Insight into Flavodiiron NO Reductases

Dong, H. T., White, C. J., Zhang, B., Krebs, C. & Lehnert, N., Oct 17 2018, In : Journal of the American Chemical Society. 140, 41, p. 13429-13440 12 p.

Research output: Contribution to journalArticle

Nitric oxide
Nitric Oxide
Bacteria
Gases
Detoxification
8 Citations (Scopus)

Non-heme High-Spin {FeNO}6-8 Complexes: One Ligand Platform Can Do It All

Speelman, A. L., White, C. J., Zhang, B., Alp, E. E., Zhao, J., Hu, M., Krebs, C., Penner-Hahn, J. & Lehnert, N., Sep 12 2018, In : Journal of the American Chemical Society. 140, 36, p. 11341-11359 19 p.

Research output: Contribution to journalArticle

Ligands
Iron
Oxidation-Reduction
Heme
Oxidation
1 Citation (Scopus)

Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase

Wang, B., Blaszczyk, A. J., Knox, H. L., Zhou, S., Blaesi, E. J., Krebs, C., Wang, R. X. & Booker, S. J., Aug 21 2018, In : Biochemistry. 57, 33, p. 4972-4984 13 p.

Research output: Contribution to journalArticle

Cytidine Monophosphate
S-Adenosylmethionine
Streptomyces
Vitamin B 12
Hydrogen
3 Citations (Scopus)

Structural and spectroscopic analyses of the sporulation killing factor biosynthetic enzyme SkfB, a bacterial AdoMet radical sactisynthase

Grell, T. A. J., Kincannon, W. M., Bruender, N. A., Blaesi, E. J., Krebs, C., Bandarian, V. & Drennan, C. L., Nov 9 2018, In : The Journal of biological chemistry. 293, 45, p. 17349-17361 13 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Enzymes
Bacillus subtilis
Sulfur
PQQ Cofactor
11 Citations (Scopus)

Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class i Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor

Rose, H. R., Ghosh, M. K., Maggiolo, A. O., Pollock, C. J., Blaesi, E. J., Hajj, V., Wei, Y., Rajakovich, L. J., Chang, W. C., Han, Y., Hajj, M., Krebs, C., Silakov, A., Pandelia, M. E., Bollinger, J. M. & Boal, A. K., May 8 2018, In : Biochemistry. 57, 18, p. 2679-2693 15 p.

Research output: Contribution to journalArticle

Flavobacterium
Ribonucleotide Reductases
Superoxides
Chemical activation
Proteins
19 Citations (Scopus)

The biosynthesis of methanobactin

Kenney, G. E., Dassama, L. M. K., Pandelia, M. E., Gizzi, A. S., Martinie, R. J., Gao, P., DeHart, C. J., Schachner, L. F., Skinner, O. S., Ro, S. Y., Zhu, X., Sadek, M., Thomas, P. M., Almo, S. C., Bollinger, J. M., Krebs, C., Kelleher, N. L. & Rosenzweig, A. C., Mar 23 2018, In : Science. 359, 6382, p. 1411-1416 6 p.

Research output: Contribution to journalArticle

Copper
Iron
Thioamides
Metals
Oxazolone
2 Citations (Scopus)

Toward a mechanistic and physiological understanding of a ferredoxin:disulfide reductase from the domains Archaea and Bacteria

Prakash, D., Walters, K. A., Martinie, X. R. J., McCarver, A. C., Kumar, A. K., Lessner, D. J., Krebs, C., Golbeck, J. H. & Ferry, J. G., Jan 1 2018, In : Journal of Biological Chemistry. 293, 24, p. 9198-9209 12 p.

Research output: Contribution to journalArticle

Ferredoxins
Archaea
Disulfides
Bacteria
Oxidoreductases
1 Citation (Scopus)

Two-Color Valence-to-Core X-ray Emission Spectroscopy Tracks Cofactor Protonation State in a Class I Ribonucleotide Reductase

Martinie, R. J., Blaesi, E. J., Bollinger, Jr., J. M., Krebs, C., Finkelstein, K. D. & Pollock, C. J., Sep 24 2018, In : Angewandte Chemie - International Edition. 57, 39, p. 12754-12758 5 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Protonation
Proton transfer
Color
Enzymes
18 Citations (Scopus)

Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of α-Heteroatom Assistance

Dunham, N. P., Chang, W. C., Mitchell, A. J., Martinie, R. J., Zhang, B., Bergman, J. A., Rajakovich, L. J., Wang, B., Silakov, A., Krebs, C., Boal, A. K. & Bollinger, Jr., J. M., Jun 13 2018, In : Journal of the American Chemical Society. 140, 23, p. 7116-7126 11 p.

Research output: Contribution to journalArticle

Glutarates
Oxygenases
Hydroxylation
Carbon
Homoarginine
5 Citations (Scopus)

α-Amine Desaturation of d -Arginine by the Iron(II)- and 2-(Oxo)glutarate-Dependent l -Arginine 3-Hydroxylase, VioC

Dunham, N. P., Mitchell, A. J., Del Río Pantoja, J. M., Krebs, C., Bollinger, J. M. & Boal, A. K., Nov 20 2018, In : Biochemistry. 57, 46, p. 6479-6488 10 p.

Research output: Contribution to journalArticle

Glutarates
Hydroxylation
Mixed Function Oxygenases
Amines
Arginine
2019

Analysis of RNA Methylation by Phylogenetically Diverse Cfr Radical S-Adenosylmethionine Enzymes Reveals an Iron-Binding Accessory Domain in a Clostridial Enzyme

Gumkowski, J. D., Martinie, R. J., Corrigan, P. S., Pan, J., Bauerle, M. R., Almarei, M., Booker, S. J., Silakov, A., Krebs, C. & Boal, A. K., Jun 27 2019, In : Biochemistry. 58, 29, p. 3169-3184 16 p.

Research output: Contribution to journalArticle

tRNA Methyltransferases
S-Adenosylmethionine
Methylation
Accessories
Rubredoxins
1 Citation (Scopus)

A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases

Rajakovich, L. J., Pandelia, M. E., Mitchell, A. J., Chang, W. C., Zhang, B., Boal, A. K., Krebs, C. & Bollinger, J. M., Mar 26 2019, In : Biochemistry. 58, 12, p. 1627-1647 21 p.

Research output: Contribution to journalArticle

Organophosphonates
Oxygenases
Iron
Degradation
gamma-Butyrobetaine Dioxygenase
2 Citations (Scopus)

Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

Dunham, N. P., Del Río Pantoja, J. M., Zhang, B., Rajakovich, L. J., Allen, B. D., Krebs, C., Boal, A. K. & Bollinger, Jr., J. M., Jun 26 2019, In : Journal of the American Chemical Society. 141, 25, p. 9964-9979 16 p.

Research output: Contribution to journalArticle

Tyrosine
Hydrogen
Atoms
Carbon
Iron
2 Citations (Scopus)

Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants

Chekan, J. R., Ongpipattanakul, C., Wright, T. R., Zhang, B., Bollinger, Jr., J. M., Rajakovich, L. J., Krebs, C., Cicchillo, R. M. & Nair, S. K., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13299-13304 6 p.

Research output: Contribution to journalArticle

Open Access
Dioxygenases
Genetically Modified Plants
Herbicides
2,4-Dichlorophenoxyacetic Acid
Indoleacetic Acids

Structure of a Ferryl Mimic in the Archetypal Iron(II)- And 2-(Oxo)-glutarate-Dependent Dioxygenase, TauD

Davis, K. M., Altmyer, M., Martinie, R. J., Schaperdoth, I., Krebs, C., Bollinger, J. M. & Boal, A. K., Oct 15 2019, In : Biochemistry. 58, 41, p. 4218-4223 6 p.

Research output: Contribution to journalArticle

Glutarates
Dioxygenases
Taurine
Iron
Hydroxylation

Substrate-Triggered Formation of a Peroxo-Fe2(III/III) Intermediate during Fatty Acid Decarboxylation by UndA

Zhang, B., Rajakovich, L. J., Van Cura, D., Blaesi, E. J., Mitchell, A. J., Tysoe, C. R., Zhu, X., Streit, B. R., Rui, Z., Zhang, W., Boal, A. K., Krebs, C. & Bollinger, J. M., Sep 18 2019, In : Journal of the American Chemical Society. 141, 37, p. 14510-14514 5 p.

Research output: Contribution to journalArticle

Decarboxylation
Fatty acids
lauric acid
Fatty Acids
Iron
2 Citations (Scopus)

Synthetic Model Complex of the Key Intermediate in Cytochrome P450 Nitric Oxide Reductase

McQuarters, A. B., Blaesi, E. J., Kampf, J. W., Alp, E. E., Zhao, J., Hu, M., Krebs, C. & Lehnert, N., Jan 22 2019, In : Inorganic Chemistry. 58, 2, p. 1398-1413 16 p.

Research output: Contribution to journalArticle

cytochromes
nitric oxide
Cytochrome P-450 Enzyme System
Electronic structure
Oxidoreductases
1 Citation (Scopus)

The Fe2(NO)2 Diamond Core: A Unique Structural Motif In Non-Heme Iron–NO Chemistry

Dong, H. T., Speelman, A. L., Kozemchak, C. E., Sil, D., Krebs, C. & Lehnert, N., Dec 2 2019, In : Angewandte Chemie - International Edition. 58, 49, p. 17695-17699 5 p.

Research output: Contribution to journalArticle

Diamond
Diamonds
Iron
Dimerization
Dimers
2020

High-resolution iron X-ray absorption spectroscopic and computational studies of non-heme diiron peroxo intermediates

Cutsail, G. E., Blaesi, E. J., Pollock, C. J., Bollinger, J. M., Krebs, C. & DeBeer, S., Feb 2020, In : Journal of Inorganic Biochemistry. 203, 110877.

Research output: Contribution to journalArticle

Open Access
X-Ray Absorption Spectroscopy
X ray absorption spectroscopy
X ray absorption
Iron
Fluorescence