• 9878 Citations
  • 57 h-Index
1995 …2023
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1995 2019

Filter
Article
2019

Analysis of RNA Methylation by Phylogenetically Diverse Cfr Radical S-Adenosylmethionine Enzymes Reveals an Iron-Binding Accessory Domain in a Clostridial Enzyme

Gumkowski, J. D., Martinie, R. J., Corrigan, P. S., Pan, J., Bauerle, M. R., Almarei, M., Booker, S. J., Silakov, A., Krebs, C. & Boal, A. K., Jun 27 2019, In : Biochemistry. 58, 29, p. 3169-3184 16 p.

Research output: Contribution to journalArticle

tRNA Methyltransferases
S-Adenosylmethionine
Methylation
Accessories
Rubredoxins
1 Citation (Scopus)

A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases

Rajakovich, L. J., Pandelia, M. E., Mitchell, A. J., Chang, W. C., Zhang, B., Boal, A. K., Krebs, C. & Bollinger, Jr., J. M., Mar 26 2019, In : Biochemistry. 58, 12, p. 1627-1647 21 p.

Research output: Contribution to journalArticle

Organophosphonates
Oxygenases
Iron
Degradation
gamma-Butyrobetaine Dioxygenase

Hydrogen Donation but not Abstraction by a Tyrosine (Y68) during Endoperoxide Installation by Verruculogen Synthase (FtmOx1)

Dunham, N. P., Del Río Pantoja, J. M., Zhang, B., Rajakovich, L. J., Allen, B. D., Krebs, C., Boal, A. K. & Bollinger, Jr., J. M., Jun 26 2019, In : Journal of the American Chemical Society. 141, 25, p. 9964-9979 16 p.

Research output: Contribution to journalArticle

Tyrosine
Hydrogen
Atoms
Carbon
Iron

Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants

Chekan, J. R., Ongpipattanakul, C., Wright, T. R., Zhang, B., Bollinger, Jr., J. M., Rajakovich, L. J., Krebs, C., Cicchillo, R. M. & Nair, S. K., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 27, p. 13299-13304 6 p.

Research output: Contribution to journalArticle

Open Access
Dioxygenases
Genetically Modified Plants
Herbicides
2,4-Dichlorophenoxyacetic Acid
Indoleacetic Acids

Substrate-Triggered Formation of a Peroxo-Fe2(III/III) Intermediate during Fatty Acid Decarboxylation by UndA

Zhang, B., Rajakovich, L. J., Van Cura, D., Blaesi, E. J., Mitchell, A. J., Tysoe, C. R., Zhu, X., Streit, B. R., Rui, Z., Zhang, W., Boal, A. K., Krebs, C. & Bollinger, Jr., J. M., Sep 18 2019, In : Journal of the American Chemical Society. 141, 37, p. 14510-14514 5 p.

Research output: Contribution to journalArticle

Decarboxylation
Fatty acids
lauric acid
Fatty Acids
Iron
1 Citation (Scopus)

Synthetic Model Complex of the Key Intermediate in Cytochrome P450 Nitric Oxide Reductase

McQuarters, A. B., Blaesi, E. J., Kampf, J. W., Alp, E. E., Zhao, J., Hu, M., Krebs, C. & Lehnert, N., Jan 22 2019, In : Inorganic Chemistry. 58, 2, p. 1398-1413 16 p.

Research output: Contribution to journalArticle

cytochromes
nitric oxide
Cytochrome P-450 Enzyme System
Electronic structure
Oxidoreductases
2018
7 Citations (Scopus)

Installation of the Ether Bridge of Lolines by the Iron- and 2-Oxoglutarate-Dependent Oxygenase, LolO: Regio- and Stereochemistry of Sequential Hydroxylation and Oxacyclization Reactions

Pan, J., Bhardwaj, M., Zhang, B., Chang, W. C., Schardl, C. L., Krebs, C., Grossman, R. B. & Bollinger, Jr., J. M., Apr 10 2018, In : Biochemistry. 57, 14, p. 2074-2083 10 p.

Research output: Contribution to journalArticle

Oxygenases
Hydroxylation
Stereochemistry
Ether
Iron
7 Citations (Scopus)

Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosinederived dihydroxyphenylalanine radical

Blaesi, E. J., Palowitch, G. M., Hu, K., Kim, A. J., Rose, H. R., Alapati, R., Lougee, M. G., Kim, H. J., Taguchi, A. T., Tan, K. O., Laremore, T. N., Griffin, R. G., Krebs, C., Matthews, M. L., Silakov, A., Bollinger, Jr., J. M., Allen, B. D. & Boal, A. K., Oct 2 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. 10022-10027 6 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Dihydroxyphenylalanine
Catalysis
Metals
Tissue Plasminogen Activator
6 Citations (Scopus)

Non-Heme Diiron Model Complexes Can Mediate Direct NO Reduction: Mechanistic Insight into Flavodiiron NO Reductases

Dong, H. T., White, C. J., Zhang, B., Krebs, C. & Lehnert, N., Oct 17 2018, In : Journal of the American Chemical Society. 140, 41, p. 13429-13440 12 p.

Research output: Contribution to journalArticle

Nitric oxide
Nitric Oxide
Bacteria
Gases
Detoxification
5 Citations (Scopus)

Non-heme High-Spin {FeNO}6-8 Complexes: One Ligand Platform Can Do It All

Speelman, A. L., White, C. J., Zhang, B., Alp, E. E., Zhao, J., Hu, M., Krebs, C., Penner-Hahn, J. & Lehnert, N., Sep 12 2018, In : Journal of the American Chemical Society. 140, 36, p. 11341-11359 19 p.

Research output: Contribution to journalArticle

Ligands
Iron
Oxidation-Reduction
Heme
Oxidation
1 Citation (Scopus)

Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase

Wang, B., Blaszczyk, A. J., Knox, H. L., Zhou, S., Blaesi, E. J., Krebs, C., Wang, R. X. & Booker, S. J., Aug 21 2018, In : Biochemistry. 57, 33, p. 4972-4984 13 p.

Research output: Contribution to journalArticle

Cytidine Monophosphate
S-Adenosylmethionine
Streptomyces
Vitamin B 12
Hydrogen
1 Citation (Scopus)

Structural and spectroscopic analyses of the sporulation killing factor biosynthetic enzyme SkfB, a bacterial AdoMet radical sactisynthase

Grell, T. A. J., Kincannon, W. M., Bruender, N. A., Blaesi, E. J., Krebs, C., Bandarian, V. & Drennan, C. L., Nov 9 2018, In : The Journal of biological chemistry. 293, 45, p. 17349-17361 13 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Enzymes
Bacillus subtilis
Sulfur
PQQ Cofactor
11 Citations (Scopus)

Structural Basis for Superoxide Activation of Flavobacterium johnsoniae Class i Ribonucleotide Reductase and for Radical Initiation by Its Dimanganese Cofactor

Rose, H. R., Ghosh, M. K., Maggiolo, A. O., Pollock, C. J., Blaesi, E. J., Hajj, V., Wei, Y., Rajakovich, L. J., Chang, W. C., Han, Y., Hajj, M., Krebs, C., Silakov, A., Pandelia, M. E., Bollinger, Jr., J. M. & Boal, A. K., May 8 2018, In : Biochemistry. 57, 18, p. 2679-2693 15 p.

Research output: Contribution to journalArticle

Flavobacterium
Ribonucleotide Reductases
Superoxides
Chemical activation
Proteins
18 Citations (Scopus)

The biosynthesis of methanobactin

Kenney, G. E., Dassama, L. M. K., Pandelia, M. E., Gizzi, A. S., Martinie, R. J., Gao, P., DeHart, C. J., Schachner, L. F., Skinner, O. S., Ro, S. Y., Zhu, X., Sadek, M., Thomas, P. M., Almo, S. C., Bollinger, Jr., J. M., Krebs, C., Kelleher, N. L. & Rosenzweig, A. C., Mar 23 2018, In : Science. 359, 6382, p. 1411-1416 6 p.

Research output: Contribution to journalArticle

Copper
Iron
Thioamides
Metals
Oxazolone
2 Citations (Scopus)

Toward a mechanistic and physiological understanding of a ferredoxin:disulfide reductase from the domains Archaea and Bacteria

Prakash, D., Walters, K. A., Martinie, X. R. J., McCarver, A. C., Kumar, A. K., Lessner, D. J., Krebs, C., Golbeck, J. H. & Ferry, J. G., Jan 1 2018, In : Journal of Biological Chemistry. 293, 24, p. 9198-9209 12 p.

Research output: Contribution to journalArticle

Ferredoxins
Archaea
Disulfides
Bacteria
Oxidoreductases

Two-Color Valence-to-Core X-ray Emission Spectroscopy Tracks Cofactor Protonation State in a Class I Ribonucleotide Reductase

Martinie, R. J., Blaesi, E. J., Bollinger, Jr., J. M., Krebs, C., Finkelstein, K. D. & Pollock, C. J., Sep 24 2018, In : Angewandte Chemie - International Edition. 57, 39, p. 12754-12758 5 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Protonation
Proton transfer
Color
Enzymes
12 Citations (Scopus)

Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of α-Heteroatom Assistance

Dunham, N. P., Chang, W. C., Mitchell, A. J., Martinie, R. J., Zhang, B., Bergman, J. A., Rajakovich, L. J., Wang, B., Silakov, A., Krebs, C., Boal, A. K. & Bollinger, Jr., J. M., Jun 13 2018, In : Journal of the American Chemical Society. 140, 23, p. 7116-7126 11 p.

Research output: Contribution to journalArticle

Glutarates
Oxygenases
Hydroxylation
Carbon
Homoarginine
4 Citations (Scopus)

α-Amine Desaturation of d -Arginine by the Iron(II)- and 2-(Oxo)glutarate-Dependent l -Arginine 3-Hydroxylase, VioC

Dunham, N. P., Mitchell, A. J., Del Río Pantoja, J. M., Krebs, C., Bollinger, Jr., J. M. & Boal, A. K., Nov 20 2018, In : Biochemistry. 57, 46, p. 6479-6488 10 p.

Research output: Contribution to journalArticle

Glutarates
Hydroxylation
Mixed Function Oxygenases
Amines
Arginine
2017
41 Citations (Scopus)

Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers

Fuller, F. D., Gul, S., Chatterjee, R., Sethe Burgie, E., Young, I. D., Lebrette, H., Srinivas, V., Brewster, A. S., Michels-Clark, T., Clinger, J. A., Andi, B., Ibrahim, M., Pastor, E., De Lichtenberg, C., Hussein, R., Pollock, C. J., Zhang, M., Stan, C. A., Kroll, T., Fransson, T. & 36 others, Weninger, C., Kubin, M., Aller, P., Lassalle, L., Bräuer, P., Miller, M. D., Amin, M., Koroidov, S., Roessler, C. G., Allaire, M., Sierra, R. G., Docker, P. T., Glownia, J. M., Nelson, S., Koglin, J. E., Zhu, D., Chollet, M., Song, S., Lemke, H., Liang, M., Sokaras, D., Alonso-Mori, R., Zouni, A., Messinger, J., Bergmann, U., Boal, A. K., Bollinger, Jr., J. M., Krebs, C., Högbom, M., Phillips, G. N., Vierstra, R. D., Sauter, N. K., Orville, A. M., Kern, J., Yachandra, V. K. & Yano, J., Feb 27 2017, In : Nature methods. 14, 4, p. 443-449 7 p.

Research output: Contribution to journalArticle

Belt drives
Phytochrome
X ray lasers
Ribonucleotide Reductases
Crystallography
9 Citations (Scopus)

Evidence for a Di-μ-oxo diamond core in the Mn(IV)/Fe(IV) activation intermediate of ribonucleotide reductase from chlamydia trachomatis

Martinie, R. J., Blaesi, E. J., Krebs, C., Bollinger, Jr., J. M., Silakov, A. & Pollock, C. J., Feb 8 2017, In : Journal of the American Chemical Society. 139, 5, p. 1950-1957 8 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Diamond
Chlamydia trachomatis
Electron Spin Resonance Spectroscopy
X ray absorption
10 Citations (Scopus)

O-H activation by an unexpected ferryl intermediate during catalysis by 2-hydroxyethylphosphonate dioxygenase

Peck, S. C., Wang, C., Dassama, L. M. K., Zhang, B., Guo, Y., Rajakovich, L. J., Bollinger, Jr., J. M., Krebs, C. & Van Der Donk, W. A., Feb 8 2017, In : Journal of the American Chemical Society. 139, 5, p. 2045-2052 8 p.

Research output: Contribution to journalArticle

Dioxygenases
Catalysis
Chemical activation
Deuterium
Herbicides
10 Citations (Scopus)

Peroxide Activation for Electrophilic Reactivity by the Binuclear Non-heme Iron Enzyme AurF

Park, K., Li, N., Kwak, Y., Srnec, M., Bell, C. B., Liu, L. V., Wong, S. D., Yoda, Y., Kitao, S., Seto, M., Hu, M., Zhao, J., Krebs, C., Bollinger, Jr., J. M. & Solomon, E. I., May 24 2017, In : Journal of the American Chemical Society. 139, 20, p. 7062-7070 9 p.

Research output: Contribution to journalArticle

Protonation
Peroxides
para-Aminobenzoates
Iron
Enzymes
4 Citations (Scopus)

The RicAFT (YmcA-YlbF-YaaT) complex carries two [4Fe-4S]2+ clusters and may respond to redox changes

Tanner, A. W., Carabetta, V. J., Martinie, R. J., Mashruwala, A. A., Boyd, J. M., Krebs, C. & Dubnau, D., Jun 1 2017, In : Molecular Microbiology. 104, 5, p. 837-850 14 p.

Research output: Contribution to journalArticle

Oxidation-Reduction
Iron-Sulfur Proteins
Proteins
Flavin-Adenine Dinucleotide
Biofilms
5 Citations (Scopus)

Vanadyl as a Stable Structural Mimic of Reactive Ferryl Intermediates in Mononuclear Nonheme-Iron Enzymes

Martinie, R. J., Pollock, C. J., Matthews, M. L., Bollinger, Jr., J. M., Krebs, C. & Silakov, A., Nov 6 2017, In : Inorganic Chemistry. 56, 21, p. 13382-13389 8 p.

Research output: Contribution to journalArticle

Vanadates
enzymes
Iron
iron
Substrates
25 Citations (Scopus)

Visualizing the reaction cycle in an Iron(II)- and 2-(Oxo)-glutarate-dependent hydroxylase

Mitchell, A. J., Dunham, N. P., Martinie, R. J., Bergman, J. A., Pollock, C. J., Hu, K., Allen, B. D., Chang, W. C., Silakov, A., Bollinger, Jr., J. M., Krebs, C. & Boal, A. K., Jan 1 2017, In : Journal of the American Chemical Society. 139, 39, p. 13830-13836 7 p.

Research output: Contribution to journalArticle

Glutarates
Oxygenases
Vanadium
Mixed Function Oxygenases
Arginine
2016
21 Citations (Scopus)

Aromatic C-F Hydroxylation by Nonheme Iron(IV)-Oxo Complexes: Structural, Spectroscopic, and Mechanistic Investigations

Sahu, S., Zhang, B., Pollock, C. J., Dürr, M., Davies, C. G., Confer, A. M., Ivanović-Burmazović, I., Siegler, M. A., Jameson, G. N. L., Krebs, C. & Goldberg, D. P., Oct 5 2016, In : Journal of the American Chemical Society. 138, 39, p. 12791-12802 12 p.

Research output: Contribution to journalArticle

Hydroxylation
Iron
Activation Analysis
ferryl iron
X-Ray Diffraction
6 Citations (Scopus)

Characterization of Lipoyl Synthase from Mycobacterium tuberculosis

Lanz, N. D., Lee, K. H., Horstmann, A. K., Pandelia, M. E., Cicchillo, R. M., Krebs, C. & Booker, S. J., Mar 8 2016, In : Biochemistry. 55, 9, p. 1372-1383 12 p.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Escherichia coli
Biosynthesis
Glycine Decarboxylase Complex H-Protein
Salvaging
27 Citations (Scopus)

Electronic Structure of the Ferryl Intermediate in the α-Ketoglutarate Dependent Non-Heme Iron Halogenase SyrB2: Contributions to H Atom Abstraction Reactivity

Srnec, M., Wong, S. D., Matthews, M. L., Krebs, C., Bollinger, Jr., J. M. & Solomon, E. I., May 4 2016, In : Journal of the American Chemical Society. 138, 15, p. 5110-5122 13 p.

Research output: Contribution to journalArticle

Anisotropy
Molecular orbitals
Electronic structure
Spectrum Analysis
Iron
7 Citations (Scopus)

Organometallic Complex Formed by an Unconventional Radical S-Adenosylmethionine Enzyme

Dong, M., Horitani, M., Dzikovski, B., Pandelia, M. E., Krebs, C., Freed, J. H., Hoffman, B. M. & Lin, H., Aug 10 2016, In : Journal of the American Chemical Society. 138, 31, p. 9755-9758 4 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Organometallics
Enzymes
Acids
Biosynthesis
31 Citations (Scopus)

Spectroscopic and Electrochemical Characterization of the Iron-Sulfur and Cobalamin Cofactors of TsrM, an Unusual Radical S-Adenosylmethionine Methylase

Blaszczyk, A. J., Silakov, A., Zhang, B., Maiocco, S. J., Lanz, N. D., Kelly, W. L., Elliott, S. J., Krebs, C. & Booker, S. J., Mar 16 2016, In : Journal of the American Chemical Society. 138, 10, p. 3416-3426 11 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Vitamin B 12
Sulfur
Iron
Enzymes
43 Citations (Scopus)

Spectroscopic Evidence for the Two C-H-Cleaving Intermediates of Aspergillus nidulans Isopenicillin N Synthase

Tamanaha, E., Zhang, B., Guo, Y., Chang, W. C., Barr, E. W., Xing, G., St Clair, J., Ye, S., Neese, F., Bollinger, Jr., J. M. & Krebs, C., Jul 20 2016, In : Journal of the American Chemical Society. 138, 28, p. 8862-8874 13 p.

Research output: Contribution to journalArticle

Thiazolidines
Aspergillus nidulans
Lactams
Aspergillus
Iron
18 Citations (Scopus)

Structural and Spectroscopic Characterization of a High-Spin {FeNO}6 Complex with an Iron(IV)-NO- Electronic Structure

Speelman, A. L., Zhang, B., Krebs, C. & Lehnert, N., Jun 1 2016, In : Angewandte Chemie - International Edition. 55, 23, p. 6685-6688 4 p.

Research output: Contribution to journalArticle

Electronic structure
Iron
Discrete Fourier transforms
Iron Compounds
Spectroelectrochemistry
24 Citations (Scopus)

Unusual Synthetic Pathway for an {Fe(NO)2}9 Dinitrosyl Iron Complex (DNIC) and Insight into DNIC Electronic Structure via Nuclear Resonance Vibrational Spectroscopy

Speelman, A. L., Zhang, B., Silakov, A., Skodje, K. M., Alp, E. E., Zhao, J., Hu, M. Y., Kim, E., Krebs, C. & Lehnert, N., Jun 6 2016, In : Inorganic Chemistry. 55, 11, p. 5485-5501 17 p.

Research output: Contribution to journalArticle

Vibrational spectroscopy
Electronic structure
electronic structure
iron
spectroscopy
2015
4 Citations (Scopus)

Direct Measurement of the Radical Translocation Distance in the Class i Ribonucleotide Reductase from Chlamydia trachomatis

Livada, J., Martinie, R. J., Dassama, L. M. K., Krebs, C., Bollinger, Jr., J. M. & Silakov, A., Oct 29 2015, In : Journal of Physical Chemistry B. 119, 43, p. 13777-13784 8 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Electron resonance
Deoxyribonucleotides
diphosphates
Ribonucleotides
12 Citations (Scopus)
Nostoc
Acyl Carrier Protein
Oxygenases
Aldehydes
Oxidoreductases
28 Citations (Scopus)

Experimental correlation of substrate position with reaction outcome in the aliphatic halogenase, SyrB2

Martinie, R. J., Livada, J., Chang, W. C., Green, M. T., Krebs, C., Bollinger, Jr., J. M. & Silakov, A., Jun 3 2015, In : Journal of the American Chemical Society. 137, 21, p. 6912-6919 8 p.

Research output: Contribution to journalArticle

Threonine
Glutarates
Aminobutyrates
Oxygenases
Deuterium
79 Citations (Scopus)

Human calprotectin is an iron-sequestering host-defense protein

Nakashige, T. G., Zhang, B., Krebs, C. & Nolan, E. M., Oct 19 2015, In : Nature Chemical Biology. 11, 10, p. 765-771 7 p.

Research output: Contribution to journalArticle

Leukocyte L1 Antigen Complex
Iron
Proteins
His-His-His-His-His-His
Manganese
24 Citations (Scopus)

Rapid Reduction of the Diferric-Peroxyhemiacetal Intermediate in Aldehyde-Deformylating Oxygenase by a Cyanobacterial Ferredoxin: Evidence for a Free-Radical Mechanism

Rajakovich, L. J., Nørgaard, H., Warui, D., Chang, W. C., Li, N., Booker, S. J., Krebs, C., Bollinger, Jr., J. M. & Pandelia, M. E., Sep 16 2015, In : Journal of the American Chemical Society. 137, 36, p. 11695-11709 15 p.

Research output: Contribution to journalArticle

formic acid
Ferredoxins
Oxygenases
Aldehydes
Free radicals
2014
13 Citations (Scopus)

ChlR protein of Synechococcus sp. PCC 7002 is a transcription activator that uses an oxygen-sensitive [4Fe-4S] cluster to control genes involved in pigment biosynthesis

Ludwig, M., Pandelia, M. E., Chew, C. Y., Zhang, B., Golbeck, J. H., Krebs, C. & Bryant, D. A., Jun 13 2014, In : Journal of Biological Chemistry. 289, 24, p. 16624-16639 16 p.

Research output: Contribution to journalArticle

Synechococcus
Biosynthesis
Transcription
Pigments
Operon
54 Citations (Scopus)

Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase

Matthews, M. L., Chang, W. C., Layne, A. P., Miles, L. A., Krebs, C. & Bollinger, Jr., J. M., Jan 1 2014, In : Nature Chemical Biology. 10, 3, p. 209-215 7 p.

Research output: Contribution to journalArticle

Anions
Carbon
Iron
Decarboxylation
Halogens
29 Citations (Scopus)

Evidence for a catalytically and kinetically competent enzyme-substrate cross-linked intermediate in catalysis by lipoyl synthase

Lanz, N. D., Pandelia, M. E., Kakar, E. S., Lee, K. H., Krebs, C. & Booker, S. J., Jul 22 2014, In : Biochemistry. 53, 28, p. 4557-4572 16 p.

Research output: Contribution to journalArticle

Catalysis
Sulfur
Methionine
Atoms
Substrates
57 Citations (Scopus)

Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics

Chang, W. C., Guo, Y., Wang, C., Butch, S. E., Rosenzweig, A. C., Boal, A. K., Krebs, C. & Bollinger, Jr., J. M., Jan 1 2014, In : Science. 343, 6175, p. 1140-1144 5 p.

Research output: Contribution to journalArticle

Lactams
Carbapenems
Tyrosine
Glutarates
Oxygenases
2013
23 Citations (Scopus)

A 2.8 Å Fe-Fe separation in the Fe 2 III/IV intermediate, X, from Escherichia coli ribonucleotide reductase

Dassama, L. M. K., Silakov, A., Krest, C. M., Calixto, J. C., Krebs, C., Bollinger, Jr., J. M. & Green, M. T., Nov 13 2013, In : Journal of the American Chemical Society. 135, 45, p. 16758-16761 4 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
X ray absorption
Escherichia coli
chlorite dismutase
X-Rays
4 Citations (Scopus)
Inositol Oxygenase
Dichroism
Inositol
Magnetic Fields
Circular Dichroism
96 Citations (Scopus)

Elucidation of the Fe(iv)=O intermediate in the catalytic cycle of the halogenase SyrB2

Wong, S. D., Srnec, M., Matthews, M. L., Liu, L. V., Kwak, Y., Park, K., Bell, C. B., Alp, E. E., Zhao, J., Yoda, Y., Kitao, S., Seto, M., Krebs, C., Bollinger, Jr., J. M. & Solomon, E. I., Jul 26 2013, In : Nature. 499, 7458, p. 320-323 4 p.

Research output: Contribution to journalArticle

Halogenation
Enzymes
Hydroxylation
Spectrum Analysis
Pseudomonas syringae
33 Citations (Scopus)

Evidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidase

Wang, C., Chang, W. C., Guo, Y., Huang, H., Peck, S. C., Pandelia, M. E., Lin, G. M., Liu, H. W., Krebs, C. & Bollinger, Jr., J. M., Jan 1 2013, In : Science. 342, 6161, p. 991-995 5 p.

Research output: Contribution to journalArticle

Fosfomycin
Organophosphonates
Epoxy Compounds
Peroxidase
Iron
29 Citations (Scopus)

Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer

Wörsdörfer, B., Conner, D. A., Yokoyama, K., Livada, J., Seyedsayamdost, M., Jiang, W., Silakov, A., Stubbe, J., Bollinger, Jr., J. M. & Krebs, C., Jun 12 2013, In : Journal of the American Chemical Society. 135, 23, p. 8585-8593 9 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Proton transfer
Escherichia coli
Protons
Amino acids
30 Citations (Scopus)

Further characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in the mechanism of catalysis

Grove, T. L., Ahlum, J. H., Qin, R. M., Lanz, N. D., Radle, M. I., Krebs, C. & Booker, S. J., Apr 30 2013, In : Biochemistry. 52, 17, p. 2874-2887 14 p.

Research output: Contribution to journalArticle

Sulfatases
Catalysis
Clostridium
Clostridium perfringens
S-Adenosylmethionine
21 Citations (Scopus)

Geometric and electronic structure of the Mn(IV)Fe(III) cofactor in class Ic ribonucleotide reductase: Correlation to the class ia binuclear non-heme iron enzyme

Kwak, Y., Jiang, W., Dassama, L. M. K., Park, K., Bell, C. B., Liu, L. V., Wong, S. D., Saito, M., Kobayashi, Y., Kitao, S., Seto, M., Yoda, Y., Alp, E. E., Zhao, J., Bollinger, Jr., J. M., Krebs, C. & Solomon, E. I., Nov 20 2013, In : Journal of the American Chemical Society. 135, 46, p. 17573-17584 12 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Vibrational spectroscopy
Dichroism
Electronic structure
Spectrum Analysis
18 Citations (Scopus)

Organophosphonate-degrading PhnZ reveals an emerging family of HD domain mixed-valent diiron oxygenases

Wörsdörfer, B., Lingaraju, M., Yennawar, N., Boal, A. K., Krebs, C., Bollinger, Jr., J. M. & Pandelia, M. E., Nov 19 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 47, p. 18874-18879 6 p.

Research output: Contribution to journalArticle

Inositol Oxygenase
Organophosphonates
Oxygenases
X Ray Crystallography
Phosphoric Monoester Hydrolases