Research output per year
Research output per year
Personal profile
Research interests
Dr. Catharine I. Paules joined the faculty of the Penn State College of Medicine in July 2018. She is a clinician-investigator with a research focus on COVID-19, emerging respiratory viruses and infections in bone marrow transplant recipients.
Dr. Paules is the site principle investigator for the NIAID sponsored Adaptive COVID-19 treatment trial and the NIH sponsored ACTIV-5 / Big Effect Trial (BET-B) for the Treatment of COVID-19. She is also involved in the COVID-19 Project ECHO for Nursing Homes.
Teaching and educational interests
Dr. Paules is committed to the mentorship and teaching of medical students, residents, fellows and other trainees.
Clinical interests
Dr. Paules sees patients in the inpatient and outpatient as an infectious diseases consultant who focuses on patients who have received (or are planned to receive) a bone marrow transplant.
Education/Academic qualification
Infectious Diseases, Fellowship, National Institutes of Health
… → 2016
Internal Medicine, Residency, University of Maryland Medical Center
… → 2014
MD, University of Nebraska
… → 2011
BS, College of William and Mary
… → 2007
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Research output
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Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data
Paules, C. I., Gallagher, S. K., Rapaka, R. R., Davey, R. T., Doernberg, S. B., Grossberg, R., Hynes, N. A., Ponce, P. O., Short, W. R., Voell, J., Wang, J., Yang, O. O., Wolfe, C. R., Lye, D. C., Dodd, L. E. & Benson, C. A., Apr 1 2022, In: Clinical Infectious Diseases. 74, 7, p. 1260-1264 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
SARS-CoV-2 vaccine effectiveness against infection, symptomatic and severe COVID-19: a systematic review and meta-analysis
Ssentongo, P., Ssentongo, A. E., Voleti, N., Groff, D., Sun, A., Ba, D. M., Nunez, J., Parent, L. J., Chinchilli, V. M. & Paules, C. I., Dec 2022, In: BMC Infectious Diseases. 22, 1, 439.Research output: Contribution to journal › Article › peer-review
Open Access -
Baricitinib plus remdesivir for hospitalized adults with Covid-19
ACTT-2 Study Group Members, Mar 4 2021, In: New England Journal of Medicine. 384, 9, p. 795-807 13 p.Research output: Contribution to journal › Article › peer-review
Open Access584 Scopus citations -
COVID-19: The therapeutic landscape
Paules, C. I. & Fauci, A. S., May 14 2021, In: Med. 2, 5, p. 493-497 5 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial
ACTT-3 study group members, Dec 2021, In: The Lancet Respiratory Medicine. 9, 12, p. 1365-1376 12 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations