Research output per year
Research output per year
Personal profile
Research interests
Dr. Chandrika Gowda is a board-certified hematologist/oncologist who has strong commitment to research in childhood cancer, including leukemia and neuroblastoma. Her major research project is to study Role of Ikaros tumor suppressor and pro-oncogenic casein Kinase II(CK2) in leukemogenesis and drug resistance. Dr.Gowda's current work is focused on targeting CK2 for treatment of hematological malignancies.
Her most notable work, published in Blood in 2015, established the novel approach of using specific CK2 inhibitors for treatment of high-risk B cell lineage leukemia using PDX models. She has presented her work at various national and international scientific forums and gained national recognition as an outstanding young investigator.
Dr. Gowda's research is currently supported by several extramural grants. She has also authored several chapters and review articles related to leukemia, CK2 and Ikaros. Her other projects are focused on designing novel therapeutic strategies for treatment of high risk neuroblastoma, which is the most common abdominal solid tumor in young children, with poor prognosis.
Education/Academic qualification
Pediatric Hematology/Oncology, Clinical Fellowship, Penn State Health Milton S. Hershey Medical Center
2010 → 2013
Pediatrics, Residency, Monmouth Medical Center
2007 → 2010
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Research output
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Increased Incidence of IKZF1 deletions and IGH-CRLF2 translocations in B-ALL of Hispanic/Latino children—a novel health disparity
Raca, G., Abdel-Azim, H., Yue, F., Broach, J., Payne, J. L., Reeves, M. E., Gowda, C., Schramm, J., Desai, D., Dovat, E., Hu, T., Berg, A. S., Bhojwani, D., Payne, K. J. & Dovat, S., 2021, (Accepted/In press) In: Leukemia.Research output: Contribution to journal › Letter › peer-review
Open Access -
Transcriptional regulation of PIK3CD and PIKFYVE in T-cell acute lymphoblastic leukemia by IKAROS and protein kinase CK2
Dovat, E., Song, C., Hu, T., Rahman, M. A., Dhanyamraju, P. K., Klink, M., Bogush, D., Soliman, M., Kane, S., McGrath, M., Ding, Y., Desai, D., Sharma, A. & Gowda, C., Jan 2 2021, In: International journal of molecular sciences. 22, 2, p. 1-14 14 p., 819.Research output: Contribution to journal › Article › peer-review
Open Access -
Cellular signaling and epigenetic regulation of gene expression in leukemia
Gowda, C., Song, C., Ding, Y., Iyer, S., Dhanyamraju, P. K., McGrath, M., Bamme, Y., Soliman, M., Kane, S., Payne, J. L. & Dovat, S., Jan 2020, In: Advances in Biological Regulation. 75, 100665.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations -
IKAROS and CK2 regulate expression of BCL-XL and chemosensitivity in high-risk B-cell acute lymphoblastic leukemia
Song, C., Ge, Z., Ding, Y., Tan, B. H., Desai, D., Gowda, K., Amin, S., Gowda, R., Robertson, G. P., Yue, F., Huang, S., Spiegelman, V., Payne, J. L., Reeves, M. E., Gurel, Z., Iyer, S., Dhanyamraju, P. K., Xiang, M., Kawasawa, Y. I., Cury, N. M. & 11 others, , Sep 24 2020, In: Blood. 136, 13, p. 1520-1534 15 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Regulation of small GTPase Rab20 by ikaros in B-cell acute lymphoblastic leukemia
Payne, J. L., Song, C., Ding, Y., Dhanyamraju, P. K., Bamme, Y., Schramm, J. W., Desai, D., Sharma, A., Gowda, C. & Dovat, S., Mar 1 2020, In: International journal of molecular sciences. 21, 5, 1718.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations