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Chandrika Gowda, MD

 https://orcid.org/0000-0003-4582-820X
    • 176 Citations
    • 7 h-Index
    20132020

    Research output per year

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    Personal profile

    Research interests

    Dr. Chandrika Gowda is a board-certified hematologist/oncologist who has strong commitment to research in childhood cancer, including leukemia and neuroblastoma. Her major research project is to study Role of Ikaros tumor suppressor and pro-oncogenic casein Kinase II(CK2) in leukemogenesis and drug resistance. Dr.Gowda's current work is focused on targeting CK2 for treatment of hematological malignancies.

    Her most notable work, published in Blood in 2015, established the novel approach of using specific CK2 inhibitors for treatment of high-risk B cell lineage leukemia using PDX models. She has presented her work at various national and international scientific forums and gained national recognition as an outstanding young investigator.

    Dr. Gowda's research is currently supported by several extramural grants. She has also authored several chapters and review articles related to leukemia, CK2 and Ikaros. Her other projects are focused on designing novel therapeutic strategies for treatment of high risk neuroblastoma, which is the most common abdominal solid tumor in young children, with poor prognosis.

    Education/Academic qualification

    Pediatric Hematology/Oncology, Clinical Fellowship, Penn State Health Milton S. Hershey Medical Center

    2010 → 2013

    Pediatrics, Residency, Monmouth Medical Center

    2007 → 2010

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    Research Output

    • 176 Citations
    • 7 h-Index
    • 5 Article
    • 4 Review article
    • 1 Chapter
    • 1 Letter

    Cellular signaling and epigenetic regulation of gene expression in leukemia

    Gowda, C., Song, C., Ding, Y., Iyer, S., Dhanyamraju, P. K., McGrath, M., Bamme, Y., Soliman, M., Kane, S., Payne, J. L. & Dovat, S., Jan 2020, In : Advances in Biological Regulation. 75, 100665.

    Research output: Contribution to journal › Review article

    Open Access
    • 2 Scopus citations

    Regulation of small GTPase Rab20 by ikaros in B-cell acute lymphoblastic leukemia

    Payne, J. L., Song, C., Ding, Y., Dhanyamraju, P. K., Bamme, Y., Schramm, J. W., Desai, D., Sharma, A., Gowda, C. & Dovat, S., Mar 1 2020, In : International journal of molecular sciences. 21, 5, 1718.

    Research output: Contribution to journal › Article

    Open Access

    • Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity

    Ding, Y., Zhang, B., Payne, J. L., Song, C., Ge, Z., Gowda, C., Iyer, S., Dhanyamraju, P. K., Dorsam, G., Reeves, M. E., Desai, D., Huang, S., Payne, K. J., Yue, F. & Dovat, S., Nov 1 2019, In : Leukemia. 33, 11, p. 2720-2731 12 p.

    Research output: Contribution to journal › Article

    Open Access
    • 5 Scopus citations

    Casein Kinase II (CK2), Glycogen Synthase Kinase-3 (GSK-3) and Ikaros mediated regulation of leukemia

    Gowda, C., Soliman, M., Kapadia, M., Ding, Y., Payne, K. & Dovat, S., Aug 2017, In : Advances in Biological Regulation. 65, p. 16-25 10 p.

    Research output: Contribution to journal › Review article

    • 15 Scopus citations

    Casein kinase II (CK2) as a therapeutic target for hematological malignancies

    Gowda, C., Sachdev, M., Muthusami, S., Kapadia, M., Petrovic-Dovat, L., Hartman, M., Ding, Y., Song, C., Payne, J. L., Tan, B. H. & Dovat, S., Jan 1 2017, In : Current Pharmaceutical Design. 23, 1, p. 95-107 13 p.

    Research output: Contribution to journal › Review article

    • 13 Scopus citations