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Chandrika Gowda, MD

 https://orcid.org/0000-0003-4582-820X
    • 150 Citations
    • 7 h-Index
    20132019
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    Research Output 2013 2019

    • 150 Citations
    • 7 h-Index
    • 4 Article
    • 4 Review article
    • 1 Chapter
    • 1 Letter
    2019

    Cellular signaling and epigenetic regulation of gene expression in leukemia

    Gowda, C., Song, C., Ding, Y., Iyer, S., Dhanyamraju, P., McGrath, M., Bamme, Y., Soliman, M., Kane, S., Payne, J. L. & Dovat, S., Jan 1 2019, (Accepted/In press) In : Advances in Biological Regulation. 100665.

    Research output: Contribution to journal › Review article

    Open Access
    Gene Expression Regulation
    Epigenomics
    Leukemia
    Ikaros Transcription Factor
    Gene Expression
    2 Citations (Scopus)

    Ikaros tumor suppressor function includes induction of active enhancers and super-enhancers along with pioneering activity

    Ding, Y., Zhang, B., Payne, J. L., Song, C., Ge, Z., Gowda, C., Iyer, S., Dhanyamraju, P. K., Dorsam, G., Reeves, M. E., Desai, D., Huang, S., Payne, K. J., Yue, F. & Dovat, S., Nov 1 2019, In : Leukemia. 33, 11, p. 2720-2731 12 p.

    Research output: Contribution to journal › Article

    Open Access
    Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
    T-Lymphocytes
    Epigenomics
    Chromatin
    Cell Differentiation
    2017
    14 Citations (Scopus)

    Casein Kinase II (CK2), Glycogen Synthase Kinase-3 (GSK-3) and Ikaros mediated regulation of leukemia

    Gowda, C., Soliman, M., Kapadia, M., Ding, Y., Payne, K. & Dovat, S., Aug 2017, In : Advances in Biological Regulation. 65, p. 16-25 10 p.

    Research output: Contribution to journal › Review article

    Phosphatidylinositol 3-Kinase
    Glycogen Synthase Kinase 3
    Casein Kinase II
    Leukemia
    Phosphorylation
    10 Citations (Scopus)

    Casein kinase II (CK2) as a therapeutic target for hematological malignancies

    Gowda, C., Sachdev, M., Muthusami, S., Kapadia, M., Petrovic-Dovat, L., Hartman, M., Ding, Y., Song, C., Payne, J. L., Tan, B. H. & Dovat, S., Jan 1 2017, In : Current Pharmaceutical Design. 23, 1, p. 95-107 13 p.

    Research output: Contribution to journal › Review article

    Casein Kinase II
    Hematologic Neoplasms
    Leukemia
    Neoplasms
    Therapeutics
    17 Citations (Scopus)

    Regulation of cellular proliferation in acute lymphoblastic leukemia by Casein Kinase II (CK2) and Ikaros

    Gowda, C., Song, C., Kapadia, M., Payne, J. L., Hu, T., Ding, Y. & Dovat, S., Jan 1 2017, In : Advances in Biological Regulation. 63, p. 71-80 10 p.

    Research output: Contribution to journal › Review article

    Casein Kinase II
    Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Leukemia
    Cell Proliferation
    Ikaros Transcription Factor
    2016
    17 Citations (Scopus)

    Epigenetic regulation of gene expression by Ikaros, HDAC1 and Casein Kinase II in leukemia

    Song, C., Pan, X., Ge, Z., Gowda, C., Ding, Y., Li, H., Li, Z., Yochum, G., Muschen, M., Li, Q., Payne, K. J. & Dovat, S., Jun 1 2016, In : Leukemia. 30, 6, p. 1436-1440 5 p.

    Research output: Contribution to journal › Letter

    6 Citations (Scopus)

    Protein signaling and regulation of gene transcription in leukemia: Role of the Casein Kinase II-Ikaros axis

    Gowda, C., Song, C., Ding, Y., Kapadia, M. & Dovat, S., Jan 1 2016, In : Journal of Investigative Medicine. 64, 3, p. 735-739 5 p.

    Research output: Contribution to journal › Article

    Casein Kinase II
    Transcription
    Leukemia
    Phosphorylation
    Genes
    24 Citations (Scopus)

    Transcriptional regulation of JARID1B/KDM5B histone demethylase by ikaros, histone deacetylase 1 (HDAC1), and casein kinase 2 (CK2) in B-cell acute lymphoblastic leukemia

    Wang, H., Song, C., Ding, Y., Pan, X., Ge, Z., Tan, B. H., Gowda, C., Sachdev, M., Muthusami, S., Ouyang, H., Lai, L., Francis, O. L., Morris, C. L., Abdel-Azim, H., Dorsam, G., Xiang, M., Payne, K. J. & Dovat, S., Feb 19 2016, In : Journal of Biological Chemistry. 291, 8, p. 4004-4018 15 p.

    Research output: Contribution to journal › Article

    Histone Demethylases
    Histone Deacetylase 1
    Casein Kinase II
    B-Lymphoid Precursor Cells
    Precursor Cell Lymphoblastic Leukemia-Lymphoma
    2015
    47 Citations (Scopus)

    Targeting casein kinase II restores Ikaros tumor suppressor activity and demonstrates therapeutic efficacy in high-risk leukemia

    Song, C., Gowda, C., Pan, X., Ding, Y., Tong, Y., Tan, B. H., Wang, H., Muthusami, S., Ge, Z., Sachdev, M., Amin, S. G., Desai, D., Gowda, K., Gowda, R., Robertson, G. P., Schjerven, H., Muschen, M., Payne, K. J. & Dovat, S., Oct 8 2015, In : Blood. 126, 15, p. 1813-1822 10 p.

    Research output: Contribution to journal › Article

    Casein Kinase II
    Tumors
    Leukemia
    Phosphatidylinositol 3-Kinase
    Genes
    2013
    13 Citations (Scopus)

    Genetic targets in pediatric acute lymphoblastic leukemia

    Gowda, C. & Dovat, S., Feb 15 2013, Impact of Genetic Targets on Cancer Therapy. El-Deiry, W. (ed.). p. 327-340 14 p. (Advances in Experimental Medicine and Biology; vol. 779).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    Pediatrics
    T-cells
    Microarrays
    Chromosomes
    Polymorphism