• 4383 Citations
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1979 …2020

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Article
2020

Clinical features and haematological parameters among malaria patients in Mangaluru city area in the southwestern coastal region of India

Punnath, K., Dayanand, K. K., Chandrashekar, V. N., Achur, R. N., Kakkilaya, S. B., Ghosh, S. K., Mukhi, B., Midya, V., Kumari, S. N. & Gowda, D. C., Mar 1 2020, In : Parasitology Research. 119, 3, p. 1043-1056 14 p.

Research output: Contribution to journalArticle

2019

Association between inflammatory cytokine levels and anemia during Plasmodium falciparum and Plasmodium vivax infections in Mangaluru: A Southwestern Coastal Region of India

Punnath, K., Dayanand, K. K., Chandrashekhar, V. N., Achur, R. N., Kakkilaya, S. B., Ghosh, S. K., Kumari, S. N. & Gowda, C., Jul 1 2019, In : Tropical Parasitology. 9, 2, p. 98-107 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Malarial anemia among pregnant women in the south-western coastal city of Mangaluru in India

Chandrashekar, V. N., Punnath, K., Dayanand, K. K., Achur, R. N., Kakkilaya, S. B., Jayadev, P., Kumari, S. N. & Gowda, D. C., 2019, In : Informatics in Medicine Unlocked. 15, 100159.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Malaria severity in Mangaluru city in the southwestern coastal region of India

Dayanand, K. K., Kishore, P., Chandrashekar, V., Achur, R. N., Ghosh, S. K., Kakkilaya, S. B., Kumari, S. N., Tiwari, S., Boloor, A., Devi, R. & Gowda, D. C., Jan 1 2019, In : American Journal of Tropical Medicine and Hygiene. 100, 2, p. 275-279 5 p.

Research output: Contribution to journalArticle

2018
5 Scopus citations

Drug resistance genes: Pvcrt-o and pvmdr-1 polymorphism in patients from malaria endemic South Western Coastal Region of India

Joy, S., Mukhi, B., Ghosh, S. K., Achur, R. N., Gowda, D. C. & Surolia, N., Jan 19 2018, In : Malaria journal. 17, 1, 40.

Research output: Contribution to journalArticle

4 Scopus citations

Presence of novel triple mutations in the pvdhfr from Plasmodium vivax in Mangaluru city area in the southwestern coastal region of India

Joy, S., Ghosh, S. K., Achur, R. N., Gowda, D. C. & Surolia, N., Apr 16 2018, In : Malaria journal. 17, 1, 167.

Research output: Contribution to journalArticle

1 Scopus citations
2017

CD36 receptor regulates malaria-induced immune responses primarily at early blood stage infection contributing to parasitemia control and resistance to mortality

Thylur, R. P., Wu, X., Gowda, N. M., Punnath, K., Neelgund, S. E., Febbraio, M. & Channe Gowda, D., Jun 2 2017, In : Journal of Biological Chemistry. 292, 22, p. 9394-9408 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Malaria prevalence in Mangaluru city area in the southwestern coastal region of India

Dayanand, K. K., Punnath, K., Chandrashekar, V., Achur, R. N., Kakkilaya, S. B., Ghosh, S. K., Kumari, S. & Gowda, D. C., Dec 19 2017, In : Malaria journal. 16, 1, 492.

Research output: Contribution to journalArticle

11 Scopus citations
4 Scopus citations
2016

Case report: Malaria transmission under an unusual circumstance causing death in two siblings

Dayanand, K. K., Punnath, K., Chandrashekar, V. N., Kakkilaya, S. B., Ghosh, S. K., Tiwari, S. N., Achur, R. N., Kadambi, S. S. & Gowda, D. C., Jul 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 1, p. 155-157 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Increased CD40 Expression Enhances Early STING-Mediated Type I Interferon Response and Host Survival in a Rodent Malaria Model

Yao, X., Wu, J., Lin, M., Sun, W., He, X., Gowda, C., Bolland, S., Long, C. A., Wang, R. & Su, X. Z., Oct 2016, In : PLoS pathogens. 12, 10, e1005930.

Research output: Contribution to journalArticle

9 Scopus citations

Inflammatory cytokine and humoral responses to plasmodium falciparum glycosylphosphatidylinositols correlates with malaria immunity and pathogenesis

Mbengue, B., Niang, B., Sylla Niang, M., Varela, M. L., Fall, B., Fall, M. M., Ndiaye Diallo, R., Diatta, B., Gowda, D. C., Dieye, A. & Perraut, R., Jan 1 2016, In : Immunity Inflammation and Disease. 4, 1, p. 24-34 11 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
2015

A non-cytotoxic N-dehydroabietylamine derivative with potent antimalarial activity

Sadashiva, M. P., Gowda, R., Wu, X., Inamdar, G. S., Kuzu, O. F., Rangappa, K. S., Robertson, G. P. & Gowda, D. C., Aug 1 2015, In : Experimental Parasitology. 155, p. 68-73 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Synthesis, antimalarial activity, and target binding of dibenzazepine-tethered isoxazolines

Vinay Kumar, K. S., Lingaraju, G. S., Bommegowda, Y. K., Vinayaka, A. C., Bhat, P., Pradeepa Kumara, C. S., Rangappa, K. S., Gowda, D. C. & Sadashiva, M. P., Jan 1 2015, In : RSC Advances. 5, 110, p. 90408-90421 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Facile synthesis of antimalarial 1,2-disubstituted 4-quinolones from 1,3-bisaryl-monothio-1,3-diketones

Vinayaka, A. C., Sadashiva, M. P., Wu, X., Biryukov, S. S., Stoute, J. A., Rangappa, K. S. & Gowda, D. C., Nov 14 2014, In : Organic and Biomolecular Chemistry. 12, 42, p. 8555-8561 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Targeted disruption of a ring-infected erythrocyte surface antigen (RESA)-like export protein gene in Plasmodium falciparum confers stable chondroitin 4-sulfate cytoadherence capacity

Goel, S., Muthusamy, A., Miao, J., Cui, L., Salanti, A., Winzeler, E. A. & Gowda, D. C., Dec 5 2014, In : Journal of Biological Chemistry. 289, 49, p. 34408-34421 14 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013

An alternative protocol for Plasmodium falciparum culture synchronization and a new method for synchrony confirmation

Childs, R. A., Miao, J., Gowda, C. & Cui, L., Nov 6 2013, In : Malaria journal. 12, 1, 386.

Research output: Contribution to journalArticle

5 Scopus citations

CD36 Contributes to Malaria Parasite-Induced Pro-Inflammatory Cytokine Production and NK and T Cell Activation by Dendritic Cells

Gowda, N. M., Wu, X., Kumar, S., Febbraio, M. & Gowda, D. C., Oct 28 2013, In : PloS one. 8, 10, e77604.

Research output: Contribution to journalArticle

17 Scopus citations

Subdural haematoma in Plasmodium falciparum and Plasmodium vivax mixed infection presenting multiple clinical complications

Devaraju, P. B., Padukone, S., Veerabhadraiah, S. R., Ramachandrappa, V. S., Panji, N., Chandrappagowda, P. B., Rudrappa, M. B., Gowda, D. C. & Achur, R. N., Dec 1 2013, In : Journal of Medical Microbiology. 62, PART 12, p. 1902-1904 3 p.

Research output: Contribution to journalArticle

2012

CD36 modulates proinflammatory cytokine responses to Plasmodium falciparum glycosylphosphatidylinositols and merozoites by dendritic cells

Kumar, S., Gowda, N. M., Wu, X., Gowda, R. N. & Gowda, D. C., Jul 1 2012, In : Parasite Immunology. 34, 7, p. 372-382 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Iκb-ζ plays an important role in the ERK-dependent dysregulation of malaria parasite GPI-induced IL-12 expression

Zhu, J., Weinberg, R., Wu, X., Gowda, N. M., Muta, T. & Gowda, D. C., Feb 2012, In : IUBMB Life. 64, 2, p. 187-193 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Plasmodium falciparum histones induce endothelial proinflammatory response and barrier dysfunction

Gillrie, M. R., Lee, K., Gowda, D. C., Davis, S. P., Monestier, M., Cui, L., Hien, T. T., Day, N. P. J. & Ho, M., Mar 2012, In : American Journal of Pathology. 180, 3, p. 1028-1039 12 p.

Research output: Contribution to journalArticle

51 Scopus citations

Targeting Toll-like receptors by chloroquine protects mice from experimental cerebral malaria

Zhu, X., Pan, Y., Li, Y., Jiang, Y., Shang, H., Gowda, D. C., Cui, L. & Cao, Y., Aug 1 2012, In : International Immunopharmacology. 13, 4, p. 392-397 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

TLR9 and MyD88 are crucial for the development of protective immunity to malaria

Gowda, N. M., Wu, X. & Gowda, D. C., May 15 2012, In : Journal of Immunology. 188, 10, p. 5073-5085 13 p.

Research output: Contribution to journalArticle

55 Scopus citations
2011

Plasmodium falciparum: Differential merozoite dose requirements for maximal production of various inflammatory cytokines

Wu, X., Gowda, N. M. & Gowda, D. C., Jan 1 2011, In : Experimental Parasitology. 127, 1, p. 202-207 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
39 Scopus citations
36 Scopus citations
2010

Dual stage synthesis and crucial role of cytoadherence-linked asexual gene 9 in the surface expression of malaria parasite var proteins

Goel, S., Valiyaveettil, M., Achur, R. N., Goyal, A., Mattei, D., Salanti, A., Trenholme, K. R., Gardiner, D. L. & Gowda, D. C., Sep 21 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 38, p. 16643-16648 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Neutralization of malaria glycosylphosphatidylinositol in vitro by serum IgG from malaria-exposed individuals

De Souza, J. B., Runglall, M., Corran, P. H., Okell, L. C., Kumar, S., Gowda, D. C., Couper, K. N. & Riley, E. M., Sep 1 2010, In : Infection and Immunity. 78, 9, p. 3920-3929 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses

Wu, X., Gowda, N. M., Kumar, S. & Gowda, D. C., Apr 15 2010, In : Journal of Immunology. 184, 8, p. 4338-4348 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Subdomain 3 of Plasmodium falciparum VAR2CSA DBL3x is identified as a minimal chondroitin sulfate A-binding region

Singh, K., Gitti, R. K., Diouf, A., Zhou, H., Gowda, D. C., Miura, K., Ostazeski, S. A., Fairhurst, R. M., Garboczi, D. N. & Long, C. A., Aug 6 2010, In : Journal of Biological Chemistry. 285, 32, p. 24855-24862 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2009

C5a enhances dysregulated inflammatory and angiogenic responses to malaria in vitro: Potential implications for placental malaria

Conroy, A., Serghides, L., Finney, C., Owino, S. O., Kumar, S., Gowda, D. C., Liles, W. C., Moore, J. M. & Kain, K. C., Mar 24 2009, In : PloS one. 4, 3, e4953.

Research output: Contribution to journalArticle

50 Scopus citations

CD36 and TLR interactions in inflammation and phagocytosis: Implications for malaria

Erdman, L. K., Cosio, G., Helmers, A. J., Gowda, D. C., Grinstein, S. & Kain, K. C., Nov 15 2009, In : Journal of Immunology. 183, 10, p. 6452-6459 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

MAPK-activated protein kinase 2 differentially regulates plasmodium falciparum glycosylphosphatidylinositol-inducedproduction of tumor necrosis Factor-α and interleukin-12 in macrophages

Zhu, J., Wu, X., Goel, S., Gowda, N. M., Kumar, S., Gowda, K., Mishra, G., Weinberg, R., Li, G., Gaestel, M., Muta, T. & Gowda, C., Jun 5 2009, In : Journal of Biological Chemistry. 284, 23, p. 15756-15761 6 p.

Research output: Contribution to journalArticle

29 Scopus citations
3 Scopus citations

Rosiglitazone modulates the innate immune response to plasmodium falciparum infection and improves outcome in experimental cerebral malaria

Serghides, L., Patel, S. N., Ayi, K., Lu, Z., Gowda, D. C., Liles, W. C. & Kain, K. C., May 15 2009, In : Journal of Infectious Diseases. 199, 10, p. 1536-1545 10 p.

Research output: Contribution to journalArticle

53 Scopus citations
10 Scopus citations
2008

Binding affinity of Plasmodium falciparum-infected erythrocytes from infected placentas and laboratory selected strains to chondroitin 4-sulfate

Achur, R. N., Muthusamy, A., Madhunapantula, S. R. V. & Gowda, D. C., May 1 2008, In : Molecular and biochemical parasitology. 159, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

C5 deficiency and C5a or C5aR blockade protects against cerebral malaria

Patel, S. N., Berghout, J., Lovegrove, F. E., Ayi, K., Conroy, A., Serghides, L., Min-Oo, G., Gowda, D. C., Sarma, J. V., Rittirsch, D., Ward, P. A., Liles, W. C., Gros, P. & Kain, K. C., May 12 2008, In : Journal of Experimental Medicine. 205, 5, p. 1133-1143 11 p.

Research output: Contribution to journalArticle

79 Scopus citations

Effect of GPI anchor moiety on the immunogenicity of DNA plasmids encoding the 19-kDa C-terminal portion of Plasmodium falciparum MSP-1

Li, G., Basagoudanavar, S. H. & Gowda, D. C., Jun 1 2008, In : Parasite Immunology. 30, 6-7, p. 315-322 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Structural interactions in chondroitin 4-sulfate mediated adherence of Plasmodium falciparum infected erythrocytes in human placenta during pregnancy-associated malaria

Achur, R. N., Kakizaki, I., Goel, S., Kojima, K., Madhunapantula, S. V., Goyal, A., Ohta, M., Kumar, S., Takagaki, K. & Gowda, C., Nov 25 2008, In : Biochemistry. 47, 47, p. 12635-12643 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A

Singh, K., Gittis, A. G., Nguyen, P., Gowda, D. C., Miller, L. H. & Garboczi, D. N., Sep 1 2008, In : Nature Structural and Molecular Biology. 15, 9, p. 932-938 7 p.

Research output: Contribution to journalArticle

72 Scopus citations
2007

Chondroitin sulfate proteoglycan but not hyaluronic acid is the receptor for the adherence of Plasmodium falciparum-infected erythrocytes in human placenta, and infected red blood cell adherence up-regulates the receptor expression

Muthusamy, A., Achur, R. N., Valiyaveettil, M., Botti, J. J., Taylor, D. W., Leke, R. F. & Gowda, D. C., Jun 2007, In : American Journal of Pathology. 170, 6, p. 1989-2000 12 p.

Research output: Contribution to journalArticle

41 Scopus citations
10 Scopus citations

Disruption of CD36 impairs cytokine response to Plasmodium falciparum glycosylphosphatidylinositol and confers susceptibility to severe and fatal malaria in vivo

Patel, S. N., Lu, Z., Ayi, K., Serghides, L., Gowda, D. C. & Kain, K. C., Mar 15 2007, In : Journal of Immunology. 178, 6, p. 3954-3961 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Plasmodium falciparum GPI mannosyltransferase-III has novel signature sequence and is functional

Basagoudanavar, S. H., Feng, X., Krishnegowda, G., Muthusamy, A. & Gowda, D. C., Dec 28 2007, In : Biochemical and Biophysical Research Communications. 364, 4, p. 748-754 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Src-family kinase-dependent disruption of endothelial barrier function by Plasmodium falciparum merozoite proteins

Gillrie, M. R., Krishnegowda, G., Lee, K., Buret, A. G., Robbins, S. M., Looareesuwan, S., Gowda, D. C. & Ho, M., Nov 1 2007, In : Blood. 110, 9, p. 3426-3435 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Structural basis for the adherence of Plasmodium falciparum-infected erythrocytes to chondroitin 4-sulfate and design of novel photoactivable reagents for the identification of parasite adhesive proteins

Gowda, A. S. P., Madhunapantula, S. R. V., Achur, R. N., Valiyaveettil, M., Bhavanandan, V. P. & Gowda, D. C., Jan 12 2007, In : Journal of Biological Chemistry. 282, 2, p. 916-928 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

The effect of substitution of the N-acetyl groups of N-acetylgalactosamine residues in chondroitin sulfate on its degradation by chondroitinase ABC

Madhunapantula, S. V., Achur, R. N., Bhavanandan, V. P. & Gowda, C., Nov 1 2007, In : Glycoconjugate Journal. 24, 8, p. 465-473 9 p.

Research output: Contribution to journalArticle

3 Scopus citations