Research Output per year
Research Output per year
Personal profile
Research interests
The overall focus of Dr. Joseph Wang's laboratory is to understand the molecular mechanisms underlying the complex life cycle of viruses using cryo-electron (cryo-EM) microscopy. His laboratory utilizes both single particle and electron tomography approaches to study virus structures as well as the interactions between viral proteins and host factors. The optimal goal is to use obtained structural information for developing effective drug intervention against virus infection.
Currently, Dr. Wang's lab has three major focuses:
- Structural study of Hepatitis B virus (HBV) and subviral particles
- Dissecting the molecular details of HBV entry and fusion process
- Molecular mechanism of alphavirus fusion
Teaching and educational interests
Dr. Wang has taught multiple courses during his graduate and postgraduate career, including Introduction to Computers (undergraduate level), Biological Electron Microscopy (graduate level) and Introduction to Quantitative Biology and Measurement (graduate level).
His philosophy of education is that the role of a teacher should not be to impress students with their knowledge of a given subject. Rather, it should be to make a subject so interesting that it inspires students to become self-motivated in learning about it.
In addition, Dr. Wang has mentored the research training of undergraduate and graduate students and served on doctoral committees for graduate students.
Dr. Wang teaches virology classes at the College of Medicine, including BMS564 Concepts in Virology (fall semester) and MICRO550 Medical Microbiology (spring semester).
Education/Academic qualification
Structural Biology, Postdoctoral Fellowship, Indiana University
2010 → 2013
Structural Biology, PhD, National Yang-Ming University
2001 → 2008
Medical Informatics, MSc, National Yang-Ming University
1999 → 2001
Biology, BSc, Fu Jen Catholic University
1995 → 1999
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Research Output
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Discovery of Exosomes From Tick Saliva and Salivary Glands Reveals Therapeutic Roles for CXCL12 and IL-8 in Wound Healing at the Tick–Human Skin Interface
Zhou, W., Tahir, F., Wang, J. C. Y., Woodson, M., Sherman, M. B., Karim, S., Neelakanta, G. & Sultana, H., Jul 16 2020, In: Frontiers in Cell and Developmental Biology. 8, 554.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Local Stabilization of Subunit-Subunit Contacts Causes Global Destabilization of Hepatitis B Virus Capsids
Schlicksup, C. J., Laughlin, P., Dunkelbarger, S., Wang, J. C. Y. & Zlotnick, A., Jun 19 2020, In: ACS chemical biology. 15, 6, p. 1708-1717 10 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Revisiting an old friend: new findings in alphavirus structure and assembly
Button, J. M., Qazi, S. A., Wang, J. C. Y. & Mukhopadhyay, S., Dec 2020, In: Current Opinion in Virology. 45, p. 25-33 9 p.Research output: Contribution to journal › Review article › peer-review
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Components of the reovirus capsid differentially contribute to stability
Snyder, A. J., Wang, J. C. Y. & Danthi, P., Jan 1 2019, In: Journal of virology. 93, 2, e01894-18.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Dissecting the Components of Sindbis Virus from Arthropod and Vertebrate Hosts: Implications for Infectivity Differences
Dunbar, C. A., Rayaprolu, V., Wang, J. C. Y., Brown, C. J., Leishman, E., Jones-Burrage, S., Trinidad, J. C., Bradshaw, H. B., Clemmer, D. E., Mukhopadhyay, S. & Jarrold, M. F., Jun 14 2019, In: ACS Infectious Diseases. 5, 6, p. 892-902 11 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations