• 3220 Citations
  • 35 h-Index
1984 …2019
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Research Output 1984 2019

  • 3220 Citations
  • 35 h-Index
  • 65 Article
  • 5 Review article
  • 1 Conference contribution
1984
83 Citations (Scopus)

Human placenta type V collagens. Evidence for the existence of an α1(V)α2(V)α3(V) collagen molecule

Niyibizi, C., Fietzek, P. P. & Van der Rest, M., Dec 1 1984, In : Journal of Biological Chemistry. 259, 22, p. 14170-14174 5 p.

Research output: Contribution to journalArticle

Collagen Type V
Placenta
Collagen
Ammonium Sulfate
Chromatography
1985
1 Citation (Scopus)

Human Placental α1(V) α2(V) α3(V) and [α1(V)]2, α2(V) Collagen Heterotrimers

VAN DER REST, MICHEL., Niyibizi, C. & FIETZEK, PETER. P., Jan 1 1985, In : Annals of the New York Academy of Sciences. 460, 1, p. 517-519 3 p.

Research output: Contribution to journalArticle

Collagen
1987
13 Citations (Scopus)
Collagen Type II
Intervertebral Disc
Cartilage
Tissue
hyaluronate lyase
1989
35 Citations (Scopus)

Bone type v collagen: Chain composition and location of a trypsin cleavage site

Niyibizi, C. & Eyre, D. R., Jan 1 1989, In : Connective Tissue Research. 20, 1-4, p. 247-250 4 p.

Research output: Contribution to journalArticle

Collagen Type V
Trypsin
Bone
Collagen
Bone and Bones
83 Citations (Scopus)

Identification of the cartilage α 1(XI) chain in type V collagen from bovine bone

Niyibizi, C. & Eyre, D. R., Jan 2 1989, In : FEBS Letters. 242, 2, p. 314-318 5 p.

Research output: Contribution to journalArticle

Collagen Type V
Cartilage
Bone
Bone and Bones
Peptides
1990
9 Citations (Scopus)

The collagens of bone and cartilage: Molecular diversity and supramolecular assembly

Eyre, D. R., Wu, J. J. & Niyibizi, C., 1990, Calcium regulation and bone metabolism. Basic and clinical aspects: proceedings of the 10th International Conference on calcium regulating hormones and bone metabolism. ICS886. Cohn, D. V., Glorieux, F. H., Martin, T. J., Cohn, D. V., Glorieux, F. H. & Martin, T. J. (eds.). Elsevier Science Publishers B.V., p. 188-194 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bone and Bones
Type 2 alpha 1 Collagenopathy
1992
12 Citations (Scopus)

Incorporation of type I collagen molecules that contain a mutant α2(I) chain (Gly580 → Asp) into bone matrix in a lethal case of osteogenesis imperfecta

Niyibizi, C., Bonadio, J., Byers, P. H. & Eyre, D. R., Nov 15 1992, In : Journal of Biological Chemistry. 267, 32, p. 23108-23112 5 p.

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Bone Matrix
Viperidae
Collagen Type I
Bone
1993
31 Citations (Scopus)
Collagen Type V
Structural analysis
Skin
Bone
Collagen
1994
46 Citations (Scopus)

A 92 kDa Gelatinase (MMP-9) cleavage site in native Type V collagen

Niyibizi, C., Chan, R., Wu, J. J. & Eyre, D., Jul 15 1994, In : Biochemical and Biophysical Research Communications. 202, 1, p. 328-333 6 p.

Research output: Contribution to journalArticle

Collagen Type V
Matrix Metalloproteinase 9
Matrix Metalloproteinases
Gelatinases
Molecules
82 Citations (Scopus)
Collagen Type V
Collagen Type I
Crosslinking
Bone
Bone and Bones
1995
42 Citations (Scopus)

Collagens in an adult bovine medial collateral ligament: Immunofluorescence localization by confocal microscopy reveals that type XIV collagen predominates at the ligament-bone junction

Niyibizi, C., Visconti, C. S., Kavalkovich, K. & Woo, S. L. Y., Jan 1 1995, In : Matrix Biology. 14, 9, p. 743-751 9 p.

Research output: Contribution to journalArticle

Collateral Ligaments
Ligaments
Confocal Microscopy
Fluorescent Antibody Technique
Collagen
1996
78 Citations (Scopus)

Biochemical analysis of collagens at the ligament-bone interface reveals presence of cartilage-specific collagens

Sagarriga Visconti, C., Kavalkovich, K., Wu, J. J. & Niyibizi, C., Apr 1 1996, In : Archives of Biochemistry and Biophysics. 328, 1, p. 135-142 8 p.

Research output: Contribution to journalArticle

Collagen Type II
Ligaments
Cartilage
Bone
Collagen Type IX
69 Citations (Scopus)

Identification and immunolocalization of type X collagen at the ligament-bone interface

Niyibizi, C., Sagarriga Visconti, C., Gibson, G. & Kavalkovich, K., May 15 1996, In : Biochemical and Biophysical Research Communications. 222, 2, p. 584-589 6 p.

Research output: Contribution to journalArticle

Collagen Type X
Ligaments
Bone
Fibrocartilage
Bone and Bones
31 Citations (Scopus)

Medial collateral ligament healing one year after a concurrent medial collateral ligament and anterior cruciate ligament injury: An interdisciplinary study in rabbits

Yamaji, T., Levine, R. E., Woo, S. L. Y., Niyibizi, C., Kavalkovich, K. W. & Weaver- Green, C. M., Mar 1 1996, In : Journal of Orthopaedic Research. 14, 2, p. 223-227 5 p.

Research output: Contribution to journalArticle

Interdisciplinary Studies
Collateral Ligaments
Anterior Cruciate Ligament
Rabbits
Knee
1997
170 Citations (Scopus)

Effect of growth factors on matrix synthesis by ligament fibroblasts

Marui, T., Niyibizi, C., Georgescu, H. I., Cao, M., Kavalkovich, K. W., Levine, R. E. & Woo, S. L. Y., Jan 1 1997, In : Journal of Orthopaedic Research. 15, 1, p. 18-23 6 p.

Research output: Contribution to journalArticle

Ligaments
Intercellular Signaling Peptides and Proteins
Fibroblasts
Anterior Cruciate Ligament
Collagen
51 Citations (Scopus)

Effect of rhBMP-2 on the osteogenic potential of bone marrow stromal cells from an osteogenesis imperfecta mouse

Balk, M. L., Bray, J., Day, C., Epperly, M., Greenberger, J., Evans, C. H. & Niyibizi, C., Jul 1 1997, In : Bone. 21, 1, p. 7-15 9 p.

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Stromal Cells
Mesenchymal Stromal Cells
Alkaline Phosphatase
Osteocalcin
39 Citations (Scopus)

Medial collateral knee ligament healing. Combined medial collateral and anterior cruciate ligament injuries studied in rabbits

Woo, S. L. Y., Niyibizi, C., Matyas, J., Kavalkovich, K., Weaver-Green, C. & Fox, R. J., Jan 1 1997, In : Acta Orthopaedica Scandinavica. 68, 2, p. 142-148 7 p.

Research output: Contribution to journalArticle

Knee Medial Collateral Ligament
Collateral Ligaments
Rabbits
Ligaments
Collagen
147 Citations (Scopus)

Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: Prolyl hydroxylase as a possible target

Cao, M., Westerhausen-Larson, A., Niyibizi, C., Kavalkovich, K., Georgescu, H. I., Rizzo, C. F., Hebda, P. A., Stefanovic-Racic, M. & Evans, C. H., May 15 1997, In : Biochemical Journal. 324, 1, p. 305-310 6 p.

Research output: Contribution to journalArticle

Prolyl Hydroxylases
Collagen Type II
Interleukin-1
Nitric Oxide
Collagen
45 Citations (Scopus)

The effects of age on rabbit MCL fibroblast matrix synthesis in response to TGF-β1 or EGF

Deie, M., Marui, T., Allen, C. R., Hildebrand, K. A., Georgescu, H. I., Niyibizi, C. & Woo, S. L. Y., Aug 1 1997, In : Mechanisms of Ageing and Development. 97, 2, p. 121-130 10 p.

Research output: Contribution to journalArticle

Collateral Ligaments
Transforming Growth Factors
Epidermal Growth Factor
Fibroblasts
Rabbits
1998
63 Citations (Scopus)

Identification of types II, IX and X collagens at the insertion site of the bovine Achilles tendon

Fukuta, S., Oyama, M., Kavalkovich, K., Fu, F. H. & Niyibizi, C., Jan 1 1998, In : Matrix Biology. 17, 1, p. 65-73 9 p.

Research output: Contribution to journalArticle

Collagen Type IX
Collagen Type X
Achilles Tendon
Collagen Type II
Calcaneus
75 Citations (Scopus)

Potential role for gene therapy in the enhancement of fracture healing

Niyibizi, C., Baltzer, A., Lattermann, C., Oyama, M., Whalen, J. D., Robbins, P. D. & Evans, C. H., Jan 1 1998, In : Clinical orthopaedics and related research. 355 SUPPL., p. S148-S153

Research output: Contribution to journalArticle

Fracture Healing
Genetic Therapy
Genes
Gene Expression
Bone and Bones
1999
69 Citations (Scopus)

Cytokine-induced tendinitis: A preliminary study in rabbits

Stone, D., Green, C., Rao, U., Aizawa, H., Yamaji, T., Niyibizi, C., Carlin, G. & Woo, S. L. Y., Dec 1 1999, In : Journal of Orthopaedic Research. 17, 2, p. 168-177 10 p.

Research output: Contribution to journalArticle

Tendinopathy
Tendons
Collagenases
Patellar Ligament
Cytokines
35 Citations (Scopus)

Intermittent sub-ambient interstitial hydrostatic pressure as a potential mechanical stimulator for chondrocyte metabolism

Suh, J. K., Baek, G. H., Arøen, A., Malin, C. M., Niyibizi, C., Evans, C. H. & Westerhausen-Larson, A., Jan 1 1999, In : Osteoarthritis and Cartilage. 7, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

Hydrostatic Pressure
Hydrostatic pressure
Chondrocytes
Metabolism
Pressure
63 Citations (Scopus)

Retrovirally transduced bone marrow stromal cells isolated from a mouse model of human osteogenesis imperfecta (oim) persist in bone and retain the ability to form cartilage and bone after extended passaging

Oyama, M., Tatlock, A., Fukuta, S., Kavalkovich, K., Nishimura, K., Johnstone, B., Robbins, P. D., Evans, C. H. & Niyibizi, C., Mar 1 1999, In : Gene Therapy. 6, 3, p. 321-329 9 p.

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Mesenchymal Stromal Cells
Cartilage
Bone and Bones
Ceramics
76 Citations (Scopus)

Transfer of LacZ marker gene to the meniscus

Goto, H., Shuler, F. D., Lamsam, C., Moller, H. D., Niyibizi, C., Fu, F. H., Robbins, P. D. & Evans, C. H., Jul 1 1999, In : Journal of Bone and Joint Surgery - Series A. 81, 7, p. 918-925 8 p.

Research output: Contribution to journalArticle

Lac Operon
Genes
Canidae
Intercellular Signaling Peptides and Proteins
Galactosidases
2000
4 Citations (Scopus)

Breakout session 4: Gene therapy for genetic diseases of bone

Lian, J. B. & Niyibizi, C., Jan 1 2000, In : Clinical orthopaedics and related research. 379 SUPPL., p. S159-S163

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Gene Transfer Techniques
Bone Neoplasms
Inborn Genetic Diseases
Bone Diseases
111 Citations (Scopus)

Ex vivo gene therapy to produce bone using different cell types

Musgrave, D. S., Bosch, P., Lee, J. Y., Pelinkovic, D., Ghivizzani, S. C., Whalen, J., Niyibizi, C. & Huard, J., Jan 1 2000, In : Clinical orthopaedics and related research. 378, p. 290-305 16 p.

Research output: Contribution to journalArticle

Genetic Therapy
Bone Morphogenetic Protein 2
Mesenchymal Stromal Cells
Bone and Bones
Muscle Cells

GAG-augmented polysaccharide hydrogel: A novel biocompatible and biodegradable material to support chondrogenesis

Sechriest, V. F., Miao, Y. J., Niyibizi, C., Westerhausen-Larson, A., Matthew, H. W., Evans, C. H., Fu, F. H. & Suh, J. K., Mar 15 2000, In : Journal of Biomedical Materials Research. 49, 4, p. 534-541 8 p.

Research output: Contribution to journalArticle

Hydrogel
Chitosan
Biocompatible Materials
Polysaccharides
Glycosaminoglycans
235 Citations (Scopus)

GAG-augmented polysaccharide hydrogel: A novel biocompatible and biodegradable material to support chondrogenesis

Sechriest, V. F., Miao, Y. J., Niyibizi, C., Westerhausen-Larson, A., Matthew, H. W., Evans, C. H., Fu, F. H. & Suh, J. K., Mar 15 2000, In : Journal of Biomedical Materials Research. 49, 4, p. 534-541 8 p.

Research output: Contribution to journalArticle

Hydrogel
Chitosan
Biocompatible Materials
Polysaccharides
Glycosaminoglycans
59 Citations (Scopus)

Gene therapy for meniscal injury: Enhanced synthesis of proteoglycan and collagen by meniscal cells transduced with a TGFβ1 gene

Goto, H., Shuler, F. D., Niyibizi, C., Fu, F. H., Robbins, P. D. & Evans, C. H., Jan 1 2000, In : Osteoarthritis and Cartilage. 8, 4, p. 266-271 6 p.

Research output: Contribution to journalArticle

Gene therapy
Proteoglycans
Collagen
Genetic Therapy
Genes
154 Citations (Scopus)

Genetic enhancement of matrix synthesis by articular chondrocytes: Comparison of different growth factor genes in the presence and absence of interleukin-1

Smith, P., Shuler, F. D., Georgescu, H. I., Ghivizzani, S. C., Johnstone, B., Niyibizi, C., Robbins, P. D. & Evans, C. H., May 1 2000, In : Arthritis and Rheumatism. 43, 5, p. 1156-1164 9 p.

Research output: Contribution to journalArticle

Genetic Enhancement
Chondrocytes
Interleukin-1
Intercellular Signaling Peptides and Proteins
Joints
93 Citations (Scopus)

Increased matrix synthesis following adenoviral transfer of a transforming growth factor β1 gene into articular chondrocytes

Shuler, F. D., Georgescu, H. I., Niyibizi, C., Studer, R. K., Mi, Z., Johnstone, B., Robbins, P. D. & Evans, C. H., Jan 1 2000, In : Journal of Orthopaedic Research. 18, 4, p. 585-592 8 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Chondrocytes
Joints
Collagen
Genes
16 Citations (Scopus)

In vivo expression of human growth hormone by genetically modified murine bone marrow stromal cells and its effect on the cells in vitro

Suzuki, K., Oyama, M., Faulcon, L., Robbins, P. D. & Niyibizi, C., Jan 1 2000, In : Cell Transplantation. 9, 3, p. 319-327 9 p.

Research output: Contribution to journalArticle

Human Growth Hormone
Hormones
Mesenchymal Stromal Cells
Bone
Femur
10 Citations (Scopus)

Novel approaches to fracture healing

Niyibizi, C. & Kim, M., Jan 1 2000, In : Expert Opinion on Investigational Drugs. 9, 7, p. 1573-1580 8 p.

Research output: Contribution to journalReview article

Fracture Healing
Genetic Therapy
Bone Morphogenetic Proteins
Bone Transplantation
Cell Separation
22 Citations (Scopus)

Potential of gene therapy for treating osteogenesis imperfecta

Niyibizi, C., Smith, P., Mi, Z., Robbins, P. & Evans, C., Jan 1 2000, In : Clinical orthopaedics and related research. 379 SUPPL., p. S126-S133

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Genetic Therapy
Genes
Mutation
Inborn Genetic Diseases
10 Citations (Scopus)

TGFβ-1-gentransfer in gelenkknorpelzellen. Stimulierende wirkung in der extrazellularen matrixsynthese

Translated title of the contribution: TGFβ-1 gene transfer in articular chondrocytesMöller, H. D., Fu, F. H., Niyibizi, C., Studer, R. K., Georgescu, H. J., Robbins, P. D. & Evans, C. H., Feb 2000, In : Der Orthopade. 29, 2, p. 75-79 5 p.

Research output: Contribution to journalArticle

Chondrocytes
Joints
Genes
Lac Operon
Cartilage

The effects of growth factors on proliferation and matrix synthesis of fibroblasts from goat medial collateral ligament

Watanabe, N., Celechovsky, C., Niyibizi, C., Wang, J. H. C., Takai, S. & Woo, S. L. Y., Dec 1 2000, In : Journal of Musculoskeletal Research. 4, 4, p. 257-264 8 p.

Research output: Contribution to journalArticle

Collateral Ligaments
Goats
Intercellular Signaling Peptides and Proteins
Fibroblast Growth Factor 2
Fibroblasts
26 Citations (Scopus)

The use of growth factors, gene therapy and tissue engineering to improve meniscal healing

Kasemkijwattana, C., Menetrey, J., Goto, H., Niyibizi, C., Fu, F. H. & Huard, J., Sep 1 2000, In : Materials Science and Engineering C. 13, 1-2, p. 19-28 10 p.

Research output: Contribution to journalArticle

gene therapy
Gene therapy
tissue engineering
healing
Tissue engineering
73 Citations (Scopus)

Type V collagen is increased during rabbit medial collateral ligament healing

Niyibizi, C., Kavalkovich, K., Yamaji, T. & Woo, S. L. Y., Jan 1 2000, In : Knee Surgery, Sports Traumatology, Arthroscopy. 8, 5, p. 281-285 5 p.

Research output: Contribution to journalArticle

Collagen Type V
Collateral Ligaments
Collagen Type III
Rabbits
Ligaments
2001
12 Citations (Scopus)

Interaction of TGF-beta1 and rhBMP-2 on human bone marrow stromal cells cultured in collagen gel matrix.

Kim, M. K. & Niyibizi, C., Jan 1 2001, In : Yonsei Medical Journal. 42, 3, p. 338-344 7 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta1
Mesenchymal Stromal Cells
Collagen
Gels
Osteoblasts
40 Citations (Scopus)

Stimulatory effect of lactate on testosterone production by rat leydig cells

Niyibizi, C., Smith, P., Mi, Z., Phillips, C. L. & Robbins, P., Sep 22 2001, In : Journal of cellular biochemistry. 83, 1, p. 147-154 8 p.

Research output: Contribution to journalArticle

Leydig Cells
Testosterone
Rats
Lactic Acid
Adenylyl Cyclases
2002
7 Citations (Scopus)

Approaches for skeletal gene therapy

Niyibizi, C., Wallach, C. J., Mi, Z. & Robbins, P. D., Dec 1 2002, In : Critical Reviews in Eukaryotic Gene Expression. 12, 3, p. 163-173 11 p.

Research output: Contribution to journalReview article

Genetic Therapy
Osteogenesis Imperfecta
Musculoskeletal Diseases
Inborn Genetic Diseases
Cell- and Tissue-Based Therapy
125 Citations (Scopus)

Muscle derived, cell based ex vivo gene therapy for treatment of full thickness articular cartilage defects

Adachi, N., Sato, K., Usas, A., Fu, F. H., Ochi, M., Han, C. W., Niyibizi, C. & Huard, J., Sep 1 2002, In : Journal of Rheumatology. 29, 9, p. 1920-1930 11 p.

Research output: Contribution to journalArticle

Articular Cartilage
Genetic Therapy
Muscle Cells
Chondrocytes
Collagen
2003
37 Citations (Scopus)

Antisense oligonucleotides reduce synthesis of procollagen α1 (V) chain in human patellar tendon fibroblasts: Potential application in healing ligaments and tendons

Shimomura, T., Jia, F., Niyibizi, C. & Woo, S. L. Y., Nov 3 2003, In : Connective Tissue Research. 44, 3-4, p. 167-172 6 p.

Research output: Contribution to journalArticle

Collagen Type V
Procollagen
Patellar Ligament
Antisense Oligonucleotides
Ligaments
2004
9 Citations (Scopus)

Feasibility of percutaneous gene transfer to an atrophic nonunion in a rabbit

Lattermann, C., Baltzer, A. W., Zelle, B. A., Whalen, J. D., Niyibizi, C., Robbins, P. D., Evans, C. H. & Gruen, G. S., Aug 2004, In : Clinical orthopaedics and related research. 425, p. 237-243 7 p.

Research output: Contribution to journalArticle

Rabbits
Genes
Transgenes
Genetic Therapy
Intercellular Signaling Peptides and Proteins
30 Citations (Scopus)

Gene therapy approaches for osteogenesis imperfecta

Niyibizi, C., Wang, S. & Robbins, P. D., Feb 1 2004, In : Gene Therapy. 11, 4, p. 408-416 9 p.

Research output: Contribution to journalReview article

Osteogenesis Imperfecta
Genetic Therapy
Inborn Genetic Diseases
Mutation
Alleles
20 Citations (Scopus)

Gene transfer to the tendon-bone insertion site

Lattermann, C., Zelle, B. A., Whalen, J. D., Baltzer, A. W. A., Robbins, P. D., Niyibizi, C., Evans, C. H. & Fu, F. H., Sep 1 2004, In : Knee Surgery, Sports Traumatology, Arthroscopy. 12, 5, p. 510-515 6 p.

Research output: Contribution to journalArticle

Tendon Transfer
Tendons
Bone and Bones
Genes
Immersion
58 Citations (Scopus)

The fate of mesenchymal stem cells transplanted into immunocompetent neonatal mice: Implications for skeletal gene therapy via stem cells

Niyibizi, C., Wang, S., Mi, Z. & Robbins, P. D., Jun 1 2004, In : Molecular Therapy. 9, 6, p. 955-963 9 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Genetic Therapy
Stem Cells
Lung
Cell Transplantation
2005
92 Citations (Scopus)

Adenoviral-mediated transfer of TGF-β1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures

Kawamura, K., Chu, C. R., Sobajima, S., Robbins, P. D., Fu, F. H., Izzo, N. J. & Niyibizi, C., Aug 1 2005, In : Experimental Hematology. 33, 8, p. 865-872 8 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Somatomedins
Mesenchymal Stromal Cells
Intercellular Signaling Peptides and Proteins
Gene Expression
6 Citations (Scopus)

Downregulation of human type III collagen gene expression by antisense oligodeoxynucleotide

Jia, F., Shimomura, T., Niyibizi, C. & Woo, S. L. Y., Sep 1 2005, In : Tissue Engineering. 11, 9-10, p. 1429-1435 7 p.

Research output: Contribution to journalArticle

Collagen
Gene expression
Tendons
Fibroblasts
Ligaments