• 3229 Citations
  • 35 h-Index
1984 …2019
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Research Output 1984 2019

  • 3229 Citations
  • 35 h-Index
  • 65 Article
  • 5 Review article
  • 1 Conference contribution
73 Citations (Scopus)

Type V collagen is increased during rabbit medial collateral ligament healing

Niyibizi, C., Kavalkovich, K., Yamaji, T. & Woo, S. L. Y., Jan 1 2000, In : Knee Surgery, Sports Traumatology, Arthroscopy. 8, 5, p. 281-285 5 p.

Research output: Contribution to journalArticle

Collagen Type V
Collateral Ligaments
Collagen Type III
Rabbits
Ligaments
76 Citations (Scopus)

Transfer of LacZ marker gene to the meniscus

Goto, H., Shuler, F. D., Lamsam, C., Moller, H. D., Niyibizi, C., Fu, F. H., Robbins, P. D. & Evans, C. H., Jul 1 1999, In : Journal of Bone and Joint Surgery - Series A. 81, 7, p. 918-925 8 p.

Research output: Contribution to journalArticle

Lac Operon
Genes
Canidae
Intercellular Signaling Peptides and Proteins
Galactosidases
26 Citations (Scopus)

The use of growth factors, gene therapy and tissue engineering to improve meniscal healing

Kasemkijwattana, C., Menetrey, J., Goto, H., Niyibizi, C., Fu, F. H. & Huard, J., Sep 1 2000, In : Materials Science and Engineering C. 13, 1-2, p. 19-28 10 p.

Research output: Contribution to journalArticle

gene therapy
Gene therapy
tissue engineering
healing
Tissue engineering
58 Citations (Scopus)

The fate of mesenchymal stem cells transplanted into immunocompetent neonatal mice: Implications for skeletal gene therapy via stem cells

Niyibizi, C., Wang, S., Mi, Z. & Robbins, P. D., Jun 1 2004, In : Molecular Therapy. 9, 6, p. 955-963 9 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Genetic Therapy
Stem Cells
Lung
Cell Transplantation
65 Citations (Scopus)

The effects of recombinant human bone morphogenetic protein-2, recombinant human bone morphogenetic protein-12, and adenoviral bone morphogenetic protein-12 on matrix synthesis in human annulus fibrosis and nucleus pulposus cells

Gilbertson, L., Ahn, S. H., Teng, P. N., Studer, R. K., Niyibizi, C. & Kang, J. D., May 1 2008, In : Spine Journal. 8, 3, p. 449-456 8 p.

Research output: Contribution to journalReview article

Fibrosis
Proteins
Bone Morphogenetic Protein 2
Intervertebral Disc
Proteoglycans

The effects of growth factors on proliferation and matrix synthesis of fibroblasts from goat medial collateral ligament

Watanabe, N., Celechovsky, C., Niyibizi, C., Wang, J. H. C., Takai, S. & Woo, S. L. Y., Dec 1 2000, In : Journal of Musculoskeletal Research. 4, 4, p. 257-264 8 p.

Research output: Contribution to journalArticle

Collateral Ligaments
Goats
Intercellular Signaling Peptides and Proteins
Fibroblast Growth Factor 2
Fibroblasts
45 Citations (Scopus)

The effects of age on rabbit MCL fibroblast matrix synthesis in response to TGF-β1 or EGF

Deie, M., Marui, T., Allen, C. R., Hildebrand, K. A., Georgescu, H. I., Niyibizi, C. & Woo, S. L. Y., Aug 1 1997, In : Mechanisms of Ageing and Development. 97, 2, p. 121-130 10 p.

Research output: Contribution to journalArticle

Collateral Ligaments
Transforming Growth Factors
Epidermal Growth Factor
Fibroblasts
Rabbits
9 Citations (Scopus)

The collagens of bone and cartilage: Molecular diversity and supramolecular assembly

Eyre, D. R., Wu, J. J. & Niyibizi, C., 1990, Calcium regulation and bone metabolism. Basic and clinical aspects: proceedings of the 10th International Conference on calcium regulating hormones and bone metabolism. ICS886. Cohn, D. V., Glorieux, F. H., Martin, T. J., Cohn, D. V., Glorieux, F. H. & Martin, T. J. (eds.). Elsevier Science Publishers B.V., p. 188-194 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bone and Bones
Type 2 alpha 1 Collagenopathy
13 Citations (Scopus)
Collagen Type II
Intervertebral Disc
Cartilage
Tissue
hyaluronate lyase
10 Citations (Scopus)

TGFβ-1-gentransfer in gelenkknorpelzellen. Stimulierende wirkung in der extrazellularen matrixsynthese

Translated title of the contribution: TGFβ-1 gene transfer in articular chondrocytesMöller, H. D., Fu, F. H., Niyibizi, C., Studer, R. K., Georgescu, H. J., Robbins, P. D. & Evans, C. H., Feb 2000, In : Der Orthopade. 29, 2, p. 75-79 5 p.

Research output: Contribution to journalArticle

Chondrocytes
Joints
Genes
Lac Operon
Cartilage
82 Citations (Scopus)
Collagen Type V
Collagen Type I
Crosslinking
Bone
Bone and Bones
31 Citations (Scopus)
Collagen Type V
Structural analysis
Skin
Bone
Collagen
40 Citations (Scopus)

Stimulatory effect of lactate on testosterone production by rat leydig cells

Niyibizi, C., Smith, P., Mi, Z., Phillips, C. L. & Robbins, P., Sep 22 2001, In : Journal of cellular biochemistry. 83, 1, p. 147-154 8 p.

Research output: Contribution to journalArticle

Leydig Cells
Testosterone
Rats
Lactic Acid
Adenylyl Cyclases
63 Citations (Scopus)

Retrovirally transduced bone marrow stromal cells isolated from a mouse model of human osteogenesis imperfecta (oim) persist in bone and retain the ability to form cartilage and bone after extended passaging

Oyama, M., Tatlock, A., Fukuta, S., Kavalkovich, K., Nishimura, K., Johnstone, B., Robbins, P. D., Evans, C. H. & Niyibizi, C., Mar 1 1999, In : Gene Therapy. 6, 3, p. 321-329 9 p.

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Mesenchymal Stromal Cells
Cartilage
Bone and Bones
Ceramics
37 Citations (Scopus)
Cell- and Tissue-Based Therapy
Osteogenesis
Green Fluorescent Proteins
Osteogenesis Imperfecta
Bone and Bones
75 Citations (Scopus)

Potential role for gene therapy in the enhancement of fracture healing

Niyibizi, C., Baltzer, A., Lattermann, C., Oyama, M., Whalen, J. D., Robbins, P. D. & Evans, C. H., Jan 1 1998, In : Clinical orthopaedics and related research. 355 SUPPL., p. S148-S153

Research output: Contribution to journalArticle

Fracture Healing
Genetic Therapy
Genes
Gene Expression
Bone and Bones
22 Citations (Scopus)

Potential of gene therapy for treating osteogenesis imperfecta

Niyibizi, C., Smith, P., Mi, Z., Robbins, P. & Evans, C., Jan 1 2000, In : Clinical orthopaedics and related research. 379 SUPPL., p. S126-S133

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Genetic Therapy
Genes
Mutation
Inborn Genetic Diseases
19 Citations (Scopus)

Potential implications of cell therapy for osteogenesis imperfecta

Niyibizi, C. & Li, F., Jan 1 2009, In : International Journal of Clinical Rheumatology. 4, 1, p. 57-66 10 p.

Research output: Contribution to journalReview article

Osteogenesis Imperfecta
Cell- and Tissue-Based Therapy
Stem Cells
Clinical Trials
Inborn Genetic Diseases
7 Citations (Scopus)
Stem cells
Mesenchymal Stromal Cells
Up-Regulation
Vascular Endothelial Growth Factor A
Bone Development
22 Citations (Scopus)
Eye Proteins
Serpins
Osteocytes
Physiologic Calcification
Bone Morphogenetic Proteins
4 Citations (Scopus)
Osteocytes
beta Catenin
Gene Expression
Catenins
Osteoblasts
34 Citations (Scopus)

Pigment epithelium-derived factor enhances differentiation and mineral deposition of human mesenchymal stem cells

Li, F., Song, N., Tombran-Tink, J. & Niyibizi, C., Dec 1 2013, In : STEM CELLS. 31, 12, p. 2714-2723 10 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Minerals
Alkaline Phosphatase
Proteins
pigment epithelium-derived factor
Osteocytes
Bone and Bones
Genes
Research Ethics Committees
Proteins
10 Citations (Scopus)

Novel approaches to fracture healing

Niyibizi, C. & Kim, M., Jan 1 2000, In : Expert Opinion on Investigational Drugs. 9, 7, p. 1573-1580 8 p.

Research output: Contribution to journalReview article

Fracture Healing
Genetic Therapy
Bone Morphogenetic Proteins
Bone Transplantation
Cell Separation
147 Citations (Scopus)

Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: Prolyl hydroxylase as a possible target

Cao, M., Westerhausen-Larson, A., Niyibizi, C., Kavalkovich, K., Georgescu, H. I., Rizzo, C. F., Hebda, P. A., Stefanovic-Racic, M. & Evans, C. H., May 15 1997, In : Biochemical Journal. 324, 1, p. 305-310 6 p.

Research output: Contribution to journalArticle

Prolyl Hydroxylases
Collagen Type II
Interleukin-1
Nitric Oxide
Collagen
125 Citations (Scopus)

Muscle derived, cell based ex vivo gene therapy for treatment of full thickness articular cartilage defects

Adachi, N., Sato, K., Usas, A., Fu, F. H., Ochi, M., Han, C. W., Niyibizi, C. & Huard, J., Sep 1 2002, In : Journal of Rheumatology. 29, 9, p. 1920-1930 11 p.

Research output: Contribution to journalArticle

Articular Cartilage
Genetic Therapy
Muscle Cells
Chondrocytes
Collagen
44 Citations (Scopus)

Multipotent mesenchymal stem cells from human subacromial bursa: Potential for cell based tendon tissue engineering

Song, N., Armstrong, A., Li, F., Ouyang, H. & Niyibizi, C., Jan 1 2014, In : Tissue Engineering - Part A. 20, 1-2, p. 239-249 11 p.

Research output: Contribution to journalArticle

Multipotent Stem Cells
Tendons
Bioelectric potentials
Tissue Engineering
Stem cells
31 Citations (Scopus)

Medial collateral ligament healing one year after a concurrent medial collateral ligament and anterior cruciate ligament injury: An interdisciplinary study in rabbits

Yamaji, T., Levine, R. E., Woo, S. L. Y., Niyibizi, C., Kavalkovich, K. W. & Weaver- Green, C. M., Mar 1 1996, In : Journal of Orthopaedic Research. 14, 2, p. 223-227 5 p.

Research output: Contribution to journalArticle

Interdisciplinary Studies
Collateral Ligaments
Anterior Cruciate Ligament
Rabbits
Knee
39 Citations (Scopus)

Medial collateral knee ligament healing. Combined medial collateral and anterior cruciate ligament injuries studied in rabbits

Woo, S. L. Y., Niyibizi, C., Matyas, J., Kavalkovich, K., Weaver-Green, C. & Fox, R. J., Jan 1 1997, In : Acta Orthopaedica Scandinavica. 68, 2, p. 142-148 7 p.

Research output: Contribution to journalArticle

Knee Medial Collateral Ligament
Collateral Ligaments
Rabbits
Ligaments
Collagen
24 Citations (Scopus)

Low oxygen tension during incubation periods of chondrocyte expansion is sufficient to enhance postexpansion chondrogenesis

Henderson, J. H., Ginley, N. M., Caplan, A. I., Niyibizi, C. & Dennis, J. E., May 1 2010, In : Tissue Engineering - Part A. 16, 5, p. 1585-1593 9 p.

Research output: Contribution to journalArticle

Chondrogenesis
Chondrocytes
Glycosaminoglycans
Oxygen
Cartilage

Isolation of mesenchymal stem cells from bone marrow with distinct differentiation and engraftment in developing mice

Li, F., Wang, X., Liao, X. & Niyibizi, C., Dec 1 2006, In : MCB Molecular and Cellular Biomechanics. 3, 4, p. 167-168 2 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Bone Marrow
Bone and Bones
16 Citations (Scopus)

In vivo expression of human growth hormone by genetically modified murine bone marrow stromal cells and its effect on the cells in vitro

Suzuki, K., Oyama, M., Faulcon, L., Robbins, P. D. & Niyibizi, C., Jan 1 2000, In : Cell Transplantation. 9, 3, p. 319-327 9 p.

Research output: Contribution to journalArticle

Human Growth Hormone
Hormones
Mesenchymal Stromal Cells
Bone
Femur
35 Citations (Scopus)

Intermittent sub-ambient interstitial hydrostatic pressure as a potential mechanical stimulator for chondrocyte metabolism

Suh, J. K., Baek, G. H., Arøen, A., Malin, C. M., Niyibizi, C., Evans, C. H. & Westerhausen-Larson, A., Jan 1 1999, In : Osteoarthritis and Cartilage. 7, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

Hydrostatic Pressure
Hydrostatic pressure
Chondrocytes
Metabolism
Pressure
12 Citations (Scopus)

Interaction of TGF-beta1 and rhBMP-2 on human bone marrow stromal cells cultured in collagen gel matrix.

Kim, M. K. & Niyibizi, C., Jun 2001, In : Yonsei medical journal. 42, 3, p. 338-344 7 p.

Research output: Contribution to journalArticle

Transforming Growth Factor beta1
Mesenchymal Stromal Cells
Collagen
Gels
Osteoblasts
93 Citations (Scopus)

Increased matrix synthesis following adenoviral transfer of a transforming growth factor β1 gene into articular chondrocytes

Shuler, F. D., Georgescu, H. I., Niyibizi, C., Studer, R. K., Mi, Z., Johnstone, B., Robbins, P. D. & Evans, C. H., Jan 1 2000, In : Journal of Orthopaedic Research. 18, 4, p. 585-592 8 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Chondrocytes
Joints
Collagen
Genes
12 Citations (Scopus)

Incorporation of type I collagen molecules that contain a mutant α2(I) chain (Gly580 → Asp) into bone matrix in a lethal case of osteogenesis imperfecta

Niyibizi, C., Bonadio, J., Byers, P. H. & Eyre, D. R., Jan 1 1992, In : Journal of Biological Chemistry. 267, 32, p. 23108-23112 5 p.

Research output: Contribution to journalArticle

Osteogenesis Imperfecta
Bone Matrix
Viperidae
Collagen Type I
Bone
63 Citations (Scopus)

Identification of types II, IX and X collagens at the insertion site of the bovine Achilles tendon

Fukuta, S., Oyama, M., Kavalkovich, K., Fu, F. H. & Niyibizi, C., Jan 1 1998, In : Matrix Biology. 17, 1, p. 65-73 9 p.

Research output: Contribution to journalArticle

Collagen Type IX
Collagen Type X
Achilles Tendon
Collagen Type II
Calcaneus
83 Citations (Scopus)

Identification of the cartilage α 1(XI) chain in type V collagen from bovine bone

Niyibizi, C. & Eyre, D. R., Jan 2 1989, In : FEBS Letters. 242, 2, p. 314-318 5 p.

Research output: Contribution to journalArticle

Collagen Type V
Cartilage
Bone
Bone and Bones
Peptides
69 Citations (Scopus)

Identification and immunolocalization of type X collagen at the ligament-bone interface

Niyibizi, C., Sagarriga Visconti, C., Gibson, G. & Kavalkovich, K., May 15 1996, In : Biochemical and Biophysical Research Communications. 222, 2, p. 584-589 6 p.

Research output: Contribution to journalArticle

Collagen Type X
Ligaments
Bone
Fibrocartilage
Bone and Bones
83 Citations (Scopus)

Human placenta type V collagens. Evidence for the existence of an α1(V)α2(V)α3(V) collagen molecule

Niyibizi, C., Fietzek, P. P. & Van der Rest, M., Dec 1 1984, In : Journal of Biological Chemistry. 259, 22, p. 14170-14174 5 p.

Research output: Contribution to journalArticle

Collagen Type V
Placenta
Collagen
Ammonium Sulfate
Chromatography
1 Citation (Scopus)

Human Placental α1(V) α2(V) α3(V) and [α1(V)]2, α2(V) Collagen Heterotrimers

VAN DER REST, MICHEL., NIYIBIZI, CHRISTOPHER. & FIETZEK, PETER. P., Dec 1985, In : Annals of the New York Academy of Sciences. 460, 1, p. 517-519 3 p.

Research output: Contribution to journalArticle

Collagen
20 Citations (Scopus)

Gene transfer to the tendon-bone insertion site

Lattermann, C., Zelle, B. A., Whalen, J. D., Baltzer, A. W. A., Robbins, P. D., Niyibizi, C., Evans, C. H. & Fu, F. H., Sep 1 2004, In : Knee Surgery, Sports Traumatology, Arthroscopy. 12, 5, p. 510-515 6 p.

Research output: Contribution to journalArticle

Tendon Transfer
Tendons
Bone and Bones
Genes
Immersion
154 Citations (Scopus)

Genetic enhancement of matrix synthesis by articular chondrocytes: Comparison of different growth factor genes in the presence and absence of interleukin-1

Smith, P., Shuler, F. D., Georgescu, H. I., Ghivizzani, S. C., Johnstone, B., Niyibizi, C., Robbins, P. D. & Evans, C. H., May 1 2000, In : Arthritis and Rheumatism. 43, 5, p. 1156-1164 9 p.

Research output: Contribution to journalArticle

Genetic Enhancement
Chondrocytes
Interleukin-1
Intercellular Signaling Peptides and Proteins
Joints
59 Citations (Scopus)

Gene therapy for meniscal injury: Enhanced synthesis of proteoglycan and collagen by meniscal cells transduced with a TGFβ1 gene

Goto, H., Shuler, F. D., Niyibizi, C., Fu, F. H., Robbins, P. D. & Evans, C. H., Jul 2000, In : Osteoarthritis and Cartilage. 8, 4, p. 266-271 6 p.

Research output: Contribution to journalArticle

Gene therapy
Proteoglycans
Collagen
Genetic Therapy
Genes
30 Citations (Scopus)

Gene therapy approaches for osteogenesis imperfecta

Niyibizi, C., Wang, S. & Robbins, P. D., Feb 1 2004, In : Gene Therapy. 11, 4, p. 408-416 9 p.

Research output: Contribution to journalReview article

Osteogenesis Imperfecta
Genetic Therapy
Inborn Genetic Diseases
Mutation
Alleles
238 Citations (Scopus)

GAG-augmented polysaccharide hydrogel: A novel biocompatible and biodegradable material to support chondrogenesis

Sechriest, V. F., Miao, Y. J., Niyibizi, C., Westerhausen-Larson, A., Matthew, H. W., Evans, C. H., Fu, F. H. & Suh, J. K., Mar 15 2000, In : Journal of Biomedical Materials Research. 49, 4, p. 534-541 8 p.

Research output: Contribution to journalArticle

Hydrogel
Chitosan
Biocompatible Materials
Polysaccharides
Glycosaminoglycans

GAG-augmented polysaccharide hydrogel: A novel biocompatible and biodegradable material to support chondrogenesis

Sechriest, V. F., Miao, Y. J., Niyibizi, C., Westerhausen-Larson, A., Matthew, H. W., Evans, C. H., Fu, F. H. & Suh, J. K., Mar 15 2000, In : Journal of Biomedical Materials Research. 49, 4, p. 534-541 8 p.

Research output: Contribution to journalArticle

Hydrogel
Chitosan
Biocompatible Materials
Polysaccharides
Glycosaminoglycans
9 Citations (Scopus)

Feasibility of percutaneous gene transfer to an atrophic nonunion in a rabbit

Lattermann, C., Baltzer, A. W., Zelle, B. A., Whalen, J. D., Niyibizi, C., Robbins, P. D., Evans, C. H. & Gruen, G. S., Aug 2004, In : Clinical orthopaedics and related research. 425, p. 237-243 7 p.

Research output: Contribution to journalArticle

Rabbits
Genes
Transgenes
Genetic Therapy
Intercellular Signaling Peptides and Proteins
111 Citations (Scopus)

Ex vivo gene therapy to produce bone using different cell types

Musgrave, D. S., Bosch, P., Lee, J. Y., Pelinkovic, D., Ghivizzani, S. C., Whalen, J., Niyibizi, C. & Huard, J., Jan 1 2000, In : Clinical orthopaedics and related research. 378, p. 290-305 16 p.

Research output: Contribution to journalArticle

Genetic Therapy
Bone Morphogenetic Protein 2
Mesenchymal Stromal Cells
Bone and Bones
Muscle Cells
4 Citations (Scopus)
Multipotent Stem Cells
Mesenchymal Stromal Cells
Transplantation
Bone Marrow
Cardiovascular System