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Christopher Siedlecki, MS, PhD

    • 3606 Citations
    • 30 h-Index
    19942019
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    Biocompatible Materials Chemical Compounds
    Biomaterials Engineering & Materials Science
    Proteins Engineering & Materials Science
    Blood Engineering & Materials Science
    Adhesion Chemical Compounds
    Factor XII Chemical Compounds
    Atomic force microscopy Engineering & Materials Science
    Platelets Engineering & Materials Science

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    Projects 2002 2016

    NANOTEXTURED POLYURETHANES FOR REDUCED PLATELET ADHESION

    Siedlecki, C.

    National Institutes of Health

    12/1/04 → 11/30/07

    Project: Research project

    Polyurethanes
    Platelets
    Adhesion
    Biocompatible Materials
    Blood

    SURFACE ENGINEERING IN CONTACT ACTIVATION OF COAGULATION

    Siedlecki, C.

    National Institutes of Health

    4/1/02 → 4/30/16

    Project: Research project

    Coagulation
    Chemical activation
    Blood
    Plasmas
    Enzyme Precursors

    Research Output 1994 2019

    3 Citations (Scopus)

    Blood coagulation response and bacterial adhesion to biomimetic polyurethane biomaterials prepared with surface texturing and nitric oxide release

    Xu, L., Meyerhoff, M. E. & Siedlecki, C., Jan 15 2019, In : Acta Biomaterialia. 84, p. 77-87 11 p.

    Research output: Contribution to journal › Article

    Bacterial Adhesion
    Biomimetics
    Polyurethanes
    Texturing
    Nitric oxide
    1 Citation (Scopus)

    Increased circulating microparticles in streptozotocin-induced diabetes propagate inflammation contributing to microvascular dysfunction

    Feng, Q., Stork, C. J., Xu, S., Yuan, D., Xia, X., LaPenna, K. B., Guo, G., Sun, H., Xu, L., Siedlecki, C., Brundage, K. M., Sheaffer, N., Schell, T. & He, P., Feb 1 2019, In : Journal of Physiology. 597, 3, p. 781-798 18 p.

    Research output: Contribution to journal › Article

    Experimental Diabetes Mellitus
    Inflammation
    Microvessels
    Phosphatidylserines
    Blood Vessels

    New textured polyphosphazene biomaterials with improved biocompatibility

    Xu, L., Chen, C., Allcock, H. R. & Siedlecki, C., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

    Biocompatible Materials
    Biocompatibility
    Biomaterials
    poly(phosphazene)
    1 Citation (Scopus)

    Stress and Exposure Time on von Willebrand Factor Degradation

    Jhun, C-S., Siedlecki, C., Xu, L., Lukic, B., Newswanger, R., Yeager, E., Reibson, J., Cysyk, J., Weiss, W. & Rosenberg, G., Feb 1 2019, In : Artificial organs. 43, 2, p. 199-206 8 p.

    Research output: Contribution to journal › Article

    von Willebrand Factor
    Molecular Weight
    Molecular weight
    Degradation
    Capillary Tubing

    The blood compatibility challenge. Part 3: Material associated activation of blood cascades and cells

    Gorbet, M., Sperling, C., Maitz, M. F., Siedlecki, C., Werner, C. & Sefton, M. V., Aug 1 2019, In : Acta Biomaterialia. 94, p. 25-32 8 p.

    Research output: Contribution to journal › Review article

    Blood Cells
    Thrombosis
    Blood
    Chemical activation
    Dissent and Disputes