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Costas D. Maranas

 https://orcid.org/0000-0002-1508-1398
    • 9417 Citations
    • 55 h-Index
    1992 …2020
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    Personal profile

    Research interests

    Computational protein design; enzyme and antibody engineering;  reconstruction, curation and analysis of metabolic networks; computational strain design and synthetic biology; metabolism of photosynthetic organisms; metabolism of obligatory anaerobes; modeling of microbial communities; optimization theory and algorithms. 

    Education/Academic qualification

    Chemical Engineering, PhD, Princeton Univercity

    Fingerprint Dive into the research topics where Costas D. Maranas is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 2 Similar Profiles
    Genome Medicine & Life Sciences
    Metabolic Networks and Pathways Medicine & Life Sciences
    Genes Engineering & Materials Science
    Escherichia coli Engineering & Materials Science
    Fluxes Engineering & Materials Science
    Metabolism Engineering & Materials Science
    Metabolites Engineering & Materials Science
    Enzymes Engineering & Materials Science

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output 1992 2020

    Metabolic model guided strain design of cyanobacteria

    Hendry, J. I., Bandyopadhyay, A., Srinivasan, S., Pakrasi, H. B. & Maranas, C. D., Aug 1 2020, In : Current Opinion in Biotechnology. 64, p. 17-23 7 p.

    Research output: Contribution to journal › Review article

    1-Butanol
    Sunlight
    Cyanobacteria
    Metabolic Networks and Pathways
    Carbon Dioxide
    4 Citations (Scopus)

    A diurnal flux balance model of Synechocystis sp. PCC 6803 metabolism

    Sarkar, D., Mueller, T. J., Liu, D., Pakrasi, H. B. & Maranas, C. D., Jan 1 2019, In : PLoS computational biology. 15, 1, e1006692.

    Research output: Contribution to journal › Article

    Synechocystis sp. PCC 6803
    Synechocystis
    Metabolism
    metabolism
    Fluxes
    20 Citations (Scopus)

    Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0

    Heirendt, L., Arreckx, S., Pfau, T., Mendoza, S. N., Richelle, A., Heinken, A., Haraldsdóttir, H. S., Wachowiak, J., Keating, S. M., Vlasov, V., Magnusdóttir, S., Ng, C. Y., Preciat, G., Žagare, A., Chan, S. H. J., Aurich, M. K., Clancy, C. M., Modamio, J., Sauls, J. T., Noronha, A. & 35 others, Bordbar, A., Cousins, B., El Assal, D. C., Valcarcel, L. V., Apaolaza, I., Ghaderi, S., Ahookhosh, M., Ben Guebila, M., Kostromins, A., Sompairac, N., Le, H. M., Ma, D., Sun, Y., Wang, L., Yurkovich, J. T., Oliveira, M. A. P., Vuong, P. T., El Assal, L. P., Kuperstein, I., Zinovyev, A., Hinton, H. S., Bryant, W. A., Aragón Artacho, F. J., Planes, F. J., Stalidzans, E., Maass, A., Vempala, S., Hucka, M., Saunders, M. A., Maranas, C. D., Lewis, N. E., Sauter, T., Palsson, B., Thiele, I. & Fleming, R. M. T., Mar 1 2019, In : Nature Protocols. 14, 3, p. 639-702 64 p.

    Research output: Contribution to journal › Article

    Biotechnology
    Reaction kinetics
    Design of experiments
    Metabolomics
    Systems Biology

    Directed Evolution Reveals the Functional Sequence Space of an Adenylation Domain Specificity Code

    Throckmorton, K., Vinnik, V., Chowdhury, R., Cook, T., Chevrette, M. G., Maranas, C. D., Pfleger, B. & Thomas, M. G., Sep 20 2019, In : ACS chemical biology. 14, 9, p. 2044-2054 11 p.

    Research output: Contribution to journal › Article

    Peptide Synthases
    Substrates
    Enterobactin
    Peptides
    Genetic Selection
    2 Citations (Scopus)

    EcoFABs: advancing microbiome science through standardized fabricated ecosystems

    Zengler, K., Hofmockel, K., Baliga, N. S., Behie, S. W., Bernstein, H. C., Brown, J. B., Dinneny, J. R., Floge, S. A., Forry, S. P., Hess, M., Jackson, S. A., Jansson, C., Lindemann, S. R., Pett-Ridge, J., Maranas, C. D., Venturelli, O. S., Wallenstein, M. D., Shank, E. A. & Northen, T. R., Jul 1 2019, In : Nature methods. 16, 7, p. 567-571 5 p.

    Research output: Contribution to journal › Comment/debate

    Microbiota
    Ecosystems
    Ecosystem
    Health