Daniela Zarnescu

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Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

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1 Similar Profiles

1 Finished
4 Active

Novel Small Molecules with Neuroprotective Potential in ALS: A 'Fly-to-Human' Approach
Zarnescu, D.
U.S. Army
5/1/22 → …
Project: Research project
Translation dysregulation in neurodegeneration
Zarnescu, D.
National Institute of Neurological Disorders and Stroke
2/15/22 → 1/31/25
Project: Research project
Novel Small Molecules with Neuroprotective Potential in ALS: A 'Fly-to-Human' Approach
Zarnescu, D.
Congressionally Directed Medical Research Programs
1/1/21 → …
Project: Research project
Small Molecules Targeting TDP-43-RNA Interactions in ALS
Zarnescu, D.
U.S. Army
7/1/18 → …
Project: Research project
Small Molecules Targeting TDP-43-RNA Interactions in ALS
Zarnescu, D.
Congressionally Directed Medical Research Programs
7/1/18 → 6/30/20
Project: Research project

39 Article
9 Review article
2 Chapter
1 Conference contribution
More
- 1 Comment/debate
- 1 Short survey

PIKFYVE inhibition mitigates disease in models of diverse forms of ALS
Hung, S. T., Linares, G. R., Chang, W. H., Eoh, Y., Krishnan, G., Mendonca, S., Hong, S., Shi, Y., Santana, M., Kueth, C., Macklin-Isquierdo, S., Perry, S., Duhaime, S., Maios, C., Chang, J., Perez, J., Couto, A., Lai, J., Li, Y., Alworth, S. V., & 8 othersHendricks, E., Wang, Y., Zlokovic, B. V., Dickman, D. K., Parker, J. A., Zarnescu, D. C., Gao, F. B. & Ichida, J. K., Feb 16 2023, In: Cell. 186, 4, p. 786-802.e28
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Dysregulation of Translation in TDP-43 Proteinopathies: Deficits in the RNA Supply Chain and Local Protein Production
Bjork, R. T., Mortimore, N. P., Loganathan, S. & Zarnescu, D. C., Mar 7 2022, In: Frontiers in Neuroscience. 16, 840357.
Research output: Contribution to journal › Review article › peer-review

Open Access
3 Scopus citations
TDP-43 Proteinopathy Causes Broad Metabolic Alterations including TCA Cycle Intermediates and Dopamine Levels in Drosophila Models of ALS
Loganathan, S., Wilson, B. A., Carey, S. B., Manzo, E., Joardar, A., Ugur, B. & Zarnescu, D. C., Feb 2022, In: Metabolites. 12, 2, 101.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Author Correction: Mutations disrupting neuritogenesis genes confer risk for cerebral palsy (Nature Genetics, (2020), 52, 10, (1046-1056), 10.1038/s41588-020-0695-1)
Jin, S. C., Lewis, S. A., Bakhtiari, S., Zeng, X., Sierant, M. C., Shetty, S., Nordlie, S. M., Elie, A., Corbett, M. A., Norton, B. Y., van Eyk, C. L., Haider, S., Guida, B. S., Magee, H., Liu, J., Pastore, S., Vincent, J. B., Brunstrom-Hernandez, J., Papavasileiou, A., Fahey, M. C., & 57 othersBerry, J. G., Harper, K., Zhou, C., Zhang, J., Li, B., Zhao, H., Heim, J., Webber, D. L., Frank, M. S. B., Xia, L., Xu, Y., Zhu, D., Zhang, B., Sheth, A. H., Knight, J. R., Castaldi, C., Tikhonova, I. R., López-Giráldez, F., Keren, B., Whalen, S., Buratti, J., Doummar, D., Cho, M., Retterer, K., Millan, F., Wang, Y., Waugh, J. L., Rodan, L., Cohen, J. S., Fatemi, A., Lin, A. E., Phillips, J. P., Feyma, T., MacLennan, S. C., Vaughan, S., Crompton, K. E., Reid, S. M., Reddihough, D. S., Shang, Q., Gao, C., Novak, I., Badawi, N., Wilson, Y. A., McIntyre, S. J., Mane, S. M., Wang, X., Amor, D. J., Zarnescu, D. C., Lu, Q., Xing, Q., Zhu, C., Bilguvar, K., Padilla-Lopez, S., Lifton, R. P., Gecz, J., MacLennan, A. H. & Kruer, M. C., Mar 2021, In: Nature Genetics. 53, 3, p. 412 1 p.
Research output: Contribution to journal › Comment/debate › peer-review

Open Access
2 Scopus citations
Measuring Glucose Uptake in Drosophila Models of TDP-43 Proteinopathy
Loganathan, S., Ball, H. E., Manzo, E. & Zarnescu, D. C., Aug 2021, In: Journal of Visualized Experiments. 2021, 174, e62936.
Research output: Contribution to journal › Article › peer-review

Daniela Zarnescu, PhD

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Expertise related to UN Sustainable Development Goals

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Novel Small Molecules with Neuroprotective Potential in ALS: A 'Fly-to-Human' Approach

Translation dysregulation in neurodegeneration

Novel Small Molecules with Neuroprotective Potential in ALS: A 'Fly-to-Human' Approach

Small Molecules Targeting TDP-43-RNA Interactions in ALS

Small Molecules Targeting TDP-43-RNA Interactions in ALS

PIKFYVE inhibition mitigates disease in models of diverse forms of ALS

Dysregulation of Translation in TDP-43 Proteinopathies: Deficits in the RNA Supply Chain and Local Protein Production

TDP-43 Proteinopathy Causes Broad Metabolic Alterations including TCA Cycle Intermediates and Dopamine Levels in Drosophila Models of ALS

Author Correction: Mutations disrupting neuritogenesis genes confer risk for cerebral palsy (Nature Genetics, (2020), 52, 10, (1046-1056), 10.1038/s41588-020-0695-1)

Measuring Glucose Uptake in Drosophila Models of TDP-43 Proteinopathy

Daniela Zarnescu, PhD

Personal profile

Expertise related to UN Sustainable Development Goals

Fingerprint

Network

Projects

Research output