• 3261 Citations
  • 20 h-Index
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Fingerprint Dive into the research topics where David D. Boehr is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
RNA Replicase Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Aminoglycosides Medicine & Life Sciences
Nucleotides Medicine & Life Sciences
Indole-3-Glycerol-Phosphate Synthase Chemical Compounds
Catalysis Medicine & Life Sciences
Tryptophan Synthase Medicine & Life Sciences

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Projects 2014 2019

RNA Replicase
RNA Viruses
Magnetic Resonance Spectroscopy

Research Output 2000 2019

2-C-methylated nucleotides terminate virus RNA synthesis by preventing active site closure of the viral RNA-dependent RNA polymerase

Boehr, A. K., Arnold, J. J., Oh, H. S., Cameron, C. E. & Boehr, D. D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 45, p. 16897-16907 11 p.

Research output: Contribution to journalArticle

RNA Replicase
RNA Viruses
Viral RNA
Catalytic Domain

Coordinated Network Changes across the Catalytic Cycle of Alpha Tryptophan Synthase

O'Rourke, K. F., Sahu, D., Bosken, Y. K., D'Amico, R. N., Chang, C. E. A. & Boehr, D. D., Sep 3 2019, In : Structure. 27, 9, p. 1405-1415.e5

Research output: Contribution to journalArticle

Tryptophan Synthase
Amino Acids
Molecular Dynamics Simulation

Energy and Enzyme Activity Landscapes of Yeast Chorismate Mutase at Cellular Concentrations of Allosteric Effectors

Gorman, S. D. & Boehr, D. D., Jan 1 2019, (Accepted/In press) In : Biochemistry.

Research output: Contribution to journalArticle

Chorismate Mutase
Enzyme activity

Engineering allostery into proteins

Gorman, S. D., D’Amico, R. N., Winston, D. S. & Boehr, D. D., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer, p. 359-384 26 p. (Advances in Experimental Medicine and Biology; vol. 1163).

Research output: Chapter in Book/Report/Conference proceedingChapter

Allosteric Regulation

Rational Control of Poliovirus RNA-Dependent RNA Polymerase Fidelity by Modulating Motif-D Loop Conformational Dynamics

Shi, J., Perryman, J. M., Yang, X., Liu, X., Musser, D. M., Boehr, A. K., Moustafa, I., Arnold, J. J., Cameron, C. E. & Boehr, D. D., Sep 10 2019, In : Biochemistry. 58, 36, p. 3735-3743 9 p.

Research output: Contribution to journalArticle

RNA Replicase
Viral RNA