Diane Thiboutot, MD

    • 8881 Citations
    • 51 h-Index
    1990 …2019
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    Research Output 1990 2019

    2019

    Assessing effectiveness in acne clinical trials: steps towards a core outcome measure set

    Thiboutot, D., Layton, A. M., Chren, M. M., Eady, E. A. & Tan, J., Jan 1 2019, (Accepted/In press) In : British Journal of Dermatology.

    Research output: Contribution to journalReview article

    Acne Vulgaris
    Outcome Assessment (Health Care)
    Clinical Trials
    Skin Diseases
    Dermatitis
    2 Citations (Scopus)

    Randomized phase 3 evaluation of trifarotene 50 μg/g cream treatment of moderate facial and truncal acne

    Tan, J., Thiboutot, D., Popp, G., Gooderham, M., Lynde, C., Del Rosso, J., Weiss, J., Blume-Peytavi, U., Weglovska, J., Johnson, S., Parish, L., Witkowska, D., Sanchez Colon, N., Alió Saenz, A., Ahmad, F., Graeber, M. & Stein Gold, L., Jun 1 2019, In : Journal of the American Academy of Dermatology. 80, 6, p. 1691-1699 9 p.

    Research output: Contribution to journalArticle

    Open Access
    Acne Vulgaris
    Research Personnel
    Safety
    Vital Signs
    Retinoids

    Update on the management of Rosacea from the American Acne & Rosacea Society (AARS)

    Del Rosso, J. Q., Tanghetti, E., Webster, G., Gold, L. S., Thiboutot, D. & Gallo, R. L., Jan 1 2019, In : Journal of Clinical and Aesthetic Dermatology. 12, 6, p. 17-24 8 p.

    Research output: Contribution to journalReview article

    Rosacea
    Therapeutics
    Physical Therapy Modalities
    Oxymetazoline
    Ivermectin
    2018
    3 Citations (Scopus)

    Artificial Intelligence for the Objective Evaluation of Acne Investigator Global Assessment

    Melina, A., Dinh, N. N., Tafuri, B., Schipani, G., Nisticò, S., Cosentino, C., Amato, F., Thiboutot, D. & Cherubini, A., Sep 1 2018, In : Journal of drugs in dermatology : JDD. 17, 9, p. 1006-1009 4 p.

    Research output: Contribution to journalArticle

    Artificial Intelligence
    Acne Vulgaris
    Research Personnel
    Ethnic Groups
    Physicians
    14 Citations (Scopus)

    Core outcome sets in dermatology: report from the second meeting of the International Cochrane Skin Group Core Outcome Set Initiative

    International Cochrane Skin Group Core Outcome Set Initiative (CSG-COUSIN) group, Apr 1 2018, In : British Journal of Dermatology. 178, 4, p. e279-e285

    Research output: Contribution to journalArticle

    Dermatology
    Clinical Trials
    Skin Diseases
    Skin
    Patient Participation
    3 Citations (Scopus)

    Development of a comprehensive quality-of-life measure for facial and torso acne

    McLellan, C., Frey, M. P., Thiboutot, D., Layton, A., Chren, M. M. & Tan, J., Jan 1 2018, In : Journal of Cutaneous Medicine and Surgery. 22, 3, p. 304-311 8 p.

    Research output: Contribution to journalArticle

    Torso
    Acne Vulgaris
    Quality of Life
    Interviews
    Psychometrics
    8 Citations (Scopus)

    Isolation and Identification of the Follicular Microbiome: Implications for Acne Research

    Hall, J. B., Cong, Z., Imamura, Y., Kidd, B. A., Dudley, J. T., Thiboutot, D. & Nelson, A., Sep 1 2018, In : Journal of Investigative Dermatology. 138, 9, p. 2033-2040 8 p.

    Research output: Contribution to journalArticle

    Microbiota
    Acne Vulgaris
    Skin
    Propionibacterium acnes
    Sampling
    30 Citations (Scopus)

    Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne

    Thiboutot, D., Dréno, B., Abanmi, A., Alexis, A. F., Araviiskaia, E., Barona Cabal, M. I., Bettoli, V., Casintahan, F., Chow, S., da Costa, A., El Ouazzani, T., Goh, C. L., Gollnick, H. P. M., Gomez, M., Hayashi, N., Herane, M. I., Honeyman, J., Kang, S., Kemeny, L., Kubba, R. & 16 others, Lambert, J., Layton, A. M., Leyden, J. J., López-Estebaranz, J. L., Noppakun, N., Ochsendorf, F., Oprica, C., Orozco, B., Perez, M., Piquero-Martin, J., See, J. A., Suh, D. H., Tan, J., Lozada, V. T., Troielli, P. & Xiang, L. F., Feb 1 2018, In : Journal of the American Academy of Dermatology. 78, 2, p. S1-S23.e1

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Delivery of Health Care
    Education
    Research
    5 Citations (Scopus)

    Rosacea comorbidities and future research: The 2017 update by the National Rosacea Society Expert Committee

    Gallo, R. L., Granstein, R. D., Kang, S., Mannis, M., Steinhoff, M., Tan, J. & Thiboutot, D., Jan 1 2018, In : Journal of the American Academy of Dermatology. 78, 1, p. 167-170 4 p.

    Research output: Contribution to journalEditorial

    Rosacea
    Comorbidity
    39 Citations (Scopus)

    Standard classification and pathophysiology of rosacea: The 2017 update by the National Rosacea Society Expert Committee

    Gallo, R. L., Granstein, R. D., Kang, S., Mannis, M., Steinhoff, M., Tan, J. & Thiboutot, D., Jan 1 2018, In : Journal of the American Academy of Dermatology. 78, 1, p. 148-155 8 p.

    Research output: Contribution to journalReview article

    Rosacea
    Phenotype
    2017
    3 Citations (Scopus)

    Development of an atrophic acne scar risk assessment tool

    Tan, J., Thiboutot, D., Gollnick, H., Kang, S., Layton, A., Leyden, J. J., Torres, V., Guillemot, J. & Dréno, B., Sep 1 2017, In : Journal of the European Academy of Dermatology and Venereology. 31, 9, p. 1547-1554 8 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Cicatrix
    Young Adult
    Population
    9 Citations (Scopus)

    Evidence-based recommendations for the management of acne fulminans and its variants

    Greywal, T., Zaenglein, A. L., Baldwin, H. E., Bhatia, N., Chernoff, K. A., Del Rosso, J. Q., Eichenfield, L. F., Levin, M. H., Leyden, J. J., Thiboutot, D. M., Webster, G. F. & Friedlander, S. F., Jul 1 2017, In : Journal of the American Academy of Dermatology. 77, 1, p. 109-117 9 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Guidelines
    Tape Recording
    Therapeutics
    Prospective Studies
    1 Citation (Scopus)

    G2A attenuates Propionibacterium acnes induction of inflammatory cytokines in human monocytes

    Park, A. J., Agak, G. W., Qin, M., Hisaw, L. D., Pirouz, A., Kao, S., Marinelli, L. J., Garbán, H. J., Thiboutot, D., Liu, P. T. & Kim, J., Dec 1 2017, In : Annals of Dermatology. 29, 6, p. 688-698 11 p.

    Research output: Contribution to journalArticle

    Propionibacterium acnes
    Monocytes
    Cytokines
    Acne Vulgaris
    Small Interfering RNA
    7 Citations (Scopus)

    Hormonal therapies for acne

    Barros, B. & Thiboutot, D., Mar 1 2017, In : Clinics in Dermatology. 35, 2, p. 168-172 5 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Androgens
    Androgen Receptors
    Therapeutics
    Chlormadinone Acetate
    4 Citations (Scopus)

    Identifying What to Measure in Acne Clinical Trials: First Steps towards Development of a Core Outcome Set

    Acne Core Outcomes Research Network (ACORN) Outcomes Identification Group, Aug 1 2017, In : Journal of Investigative Dermatology. 137, 8, p. 1784-1786 3 p.

    Research output: Contribution to journalArticle

    10 Citations (Scopus)

    Inhibition of Sebum Production with the Acetyl Coenzyme A Carboxylase Inhibitor Olumacostat Glasaretil

    Hunt, D. W., Winters, G. C., Brownsey, R. W., Kulpa, J. E., Gilliland, K. L., Thiboutot, D. & Hofland, H. E., Jul 1 2017, In : Journal of Investigative Dermatology. 137, 7, p. 1415-1423 9 p.

    Research output: Contribution to journalArticle

    Sebum
    Acetyl-CoA Carboxylase
    Sebaceous Glands
    Fatty Acids
    Ear
    41 Citations (Scopus)

    Rosacea treatment update: recommendations from the global ROSacea COnsensus (ROSCO) panel

    Schaller, M., Almeida, L. M. C., Bewley, A., Cribier, B., Dlova, N. C., Kautz, G., Mannis, M., Oon, H. H., Rajagopalan, M., Steinhoff, M., Thiboutot, D., Troielli, P., Webster, G., Wu, Y., van Zuuren, E. & Tan, J., Feb 1 2017, In : British Journal of Dermatology. 176, 2, p. 465-471 7 p.

    Research output: Contribution to journalArticle

    Rosacea
    Therapeutics
    Phenotype
    Telangiectasis
    Patient Preference
    11 Citations (Scopus)

    Shortcomings in rosacea diagnosis and classification

    Tan, J., Steinhoff, M., Berg, M., Del Rosso, J., Layton, A., Leyden, J., Schauber, J., Schaller, M., Cribier, B., Thiboutot, D., Webster, G. & the Rosacea International Study Group, Jan 1 2017, In : British Journal of Dermatology. 176, 1, p. 197-199 3 p.

    Research output: Contribution to journalArticle

    55 Citations (Scopus)

    Updating the diagnosis, classification and assessment of rosacea: recommendations from the global ROSacea COnsensus (ROSCO) panel

    Tan, J., Almeida, L. M. C., Bewley, A., Cribier, B., Dlova, N. C., Gallo, R., Kautz, G., Mannis, M., Oon, H. H., Rajagopalan, M., Steinhoff, M., Thiboutot, D., Troielli, P., Webster, G., Wu, Y., van Zuuren, E. J. & Schaller, M., Feb 1 2017, In : British Journal of Dermatology. 176, 2, p. 431-438 8 p.

    Research output: Contribution to journalArticle

    Rosacea
    Phenotype
    Eye Manifestations
    Telangiectasis
    Politics
    2016

    Antimicrobial Activity of Sebocytes against Propionibacterium acnes via Toll-Like Receptor 2 and Lysosomal Pathway

    Hisaw, L. D., Qin, M., Park, A., Agak, G. W., Pirouz, A., Phan, J., Fernandez, C., Garbán, H. J., Nelson, A., Thiboutot, D. & Kim, J., Oct 1 2016, In : Journal of Investigative Dermatology. 136, 10, p. 2098-2101 4 p.

    Research output: Contribution to journalArticle

    Toll-Like Receptor 2
    17 Citations (Scopus)

    Consumption of dairy in teenagers with and without acne

    LaRosa, C. L., Quach, K. A., Koons, K., Kunselman, A. R., Zhu, J., Thiboutot, D. M. & Zaenglein, A. L., Aug 1 2016, In : Journal of the American Academy of Dermatology. 75, 2, p. 318-322 5 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Fats
    Milk
    Portion Size
    Diet
    5 Citations (Scopus)

    Efficacy, safety, and dermal tolerability of dapsone gel, 7.5% in patients with moderate acne vulgaris: A pooled analysis of two phase 3 trials

    Thiboutot, D. M., Kircik, L., Mcmichael, A., Cook-Bolden, F. E., Tyring, S. K., Berk, D. R., Chang-Lin, J. E., Lin, V. & Kaoukhov, A., Oct 1 2016, In : Journal of Clinical and Aesthetic Dermatology. 9, 10, p. 18-27 10 p.

    Research output: Contribution to journalArticle

    Dapsone
    Acne Vulgaris
    Gels
    Safety
    Skin
    3 Citations (Scopus)

    New Patient-Oriented Tools for Assessing Atrophic Acne Scarring

    Layton, A., Dréno, B., Finlay, A. Y., Thiboutot, D., Kang, S., Lozada, V. T., Bourdès, V., Bettoli, V., Petit, L. & Tan, J., Jun 1 2016, In : Dermatology and Therapy. 6, 2, p. 219-233 15 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Cicatrix
    Quality of Life
    Interviews
    Psychology
    2 Citations (Scopus)

    Safe use of therapeutic-dose oral isotretinoin in patients with a history of pseudotumor cerebri

    Tintle, S. J., Harper, J. C., Webster, G. F., Kim, G. K. & Thiboutot, D. M., May 1 2016, In : JAMA Dermatology. 152, 5, p. 582-584 3 p.

    Research output: Contribution to journalLetter

    Pseudotumor Cerebri
    Isotretinoin
    Therapeutic Uses
    1 Citation (Scopus)

    Selective Rho Kinase Inhibitor Allows for Expansion of Human Primary Sebocytes In Vitro

    Nelson, A. M., Dispenza, M. C., Cong, Z., Moll, M., Gilliland, K. L. & Thiboutot, D. M., Jan 1 2016, In : Journal of Investigative Dermatology. 136, 6, p. 1278-1280 3 p.

    Research output: Contribution to journalArticle

    Pyridines
    Sebaceous Glands
    rho-Associated Kinases
    Amides
    Cell Proliferation
    14 Citations (Scopus)

    Standardized laboratory monitoring with use of isotretinoin in acne

    Hansen, T. J., Lucking, S. M., Miller, J. J., Kirby, J. S., Thiboutot, D. M. & Zaenglein, A. L., Aug 1 2016, In : Journal of the American Academy of Dermatology. 75, 2, p. 323-328 6 p.

    Research output: Contribution to journalArticle

    Isotretinoin
    Acne Vulgaris
    Blood Cell Count
    Quality of Health Care
    Hypertriglyceridemia
    6 Citations (Scopus)

    Status report from the scientific panel on antibiotic use in dermatology of the American acne and rosacea society

    Rosso, J. Q. D., Gallo, R. L., Thiboutot, D., Webster, G. F., Rosen, T., Leyden, J. J., Walker, C., Zhanel, G. & Eichenfield, L., May 1 2016, In : Journal of Clinical and Aesthetic Dermatology. 9, 5, p. 11-17 7 p.

    Research output: Contribution to journalArticle

    Rosacea
    Dermatology
    Microbiota
    Anti-Bacterial Agents
    Isotretinoin
    12 Citations (Scopus)
    Rosacea
    Microbial Drug Resistance
    Dermatology
    Anti-Bacterial Agents
    Acne Vulgaris
    6 Citations (Scopus)
    Rosacea
    Soft Tissue Infections
    Methicillin-Resistant Staphylococcus aureus
    Dermatology
    Anti-Bacterial Agents
    2015
    12 Citations (Scopus)

    Activity-guided purification identifies lupeol, a pentacyclic triterpene, as a therapeutic agent targeting multiple pathogenic factors of acne

    Kwon, H. H., Yoon, J. Y., Park, S. Y., Min, S., Kim, Y. I., Park, J. Y., Lee, Y. S., Thiboutot, D. M. & Suh, D. H., Jan 1 2015, In : Journal of Investigative Dermatology. 135, 6, p. 1491-1500 10 p.

    Research output: Contribution to journalArticle

    Pentacyclic Triterpenes
    Acne Vulgaris
    Purification
    Therapeutics
    Solanum melongena
    45 Citations (Scopus)

    Large-scale international study enhances understanding of an emerging acne population: Adult females

    Dréno, B., Thiboutot, D., Layton, A. M., Berson, D., Perez, M. & Kang, S., Jun 1 2015, In : Journal of the European Academy of Dermatology and Venereology. 29, 6, p. 1096-1106 11 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Population
    Adult Acne
    Dermatology
    Life Style
    19 Citations (Scopus)
    cell fusion
    Cell Fusion
    Macrophages
    melanoma
    Tumors
    5 Citations (Scopus)

    Status report from the American Acne & Rosacea Society on medical management of acne in adult women, part 1: Overview, clinical characteristics, and laboratory evaluation

    Del Rosso, J. Q., Harper, J. C., Graber, E. M., Thiboutot, D., Silverberg, N. B., Eichenfield, D. Z. & Eichenfield, L. F., Jan 1 2015, In : Cutis. 96, 4, p. 236-241 6 p.

    Research output: Contribution to journalArticle

    Rosacea
    Medical Societies
    Acne Vulgaris
    Self Concept
    Androgens
    3 Citations (Scopus)

    Status report from the American acne & rosacea society on medical management of acne in adult women, part 2: Topical therapies

    Del Rosso, J. Q., Harper, J. C., Graber, E. M., Thiboutot, D., Silverberg, N. B. & Eichenfield, L. F., Jan 1 2015, In : Cutis. 96, 5, p. 321-325 5 p.

    Research output: Contribution to journalArticle

    Rosacea
    Medical Societies
    Acne Vulgaris
    Skin Care
    Prescriptions
    3 Citations (Scopus)

    Status report from the American acne & rosacea society on medical management of acne in adult women, part 3: Oral therapies

    Del Rosso, J. Q., Harper, J. C., Graber, E. M., Thiboutot, D., Silverberg, N. B. & Eichenfield, L. F., Jan 1 2015, In : Cutis. 96, 6, p. 376-382 7 p.

    Research output: Contribution to journalReview article

    Rosacea
    Medical Societies
    Acne Vulgaris
    Skin Care
    Isotretinoin
    43 Citations (Scopus)

    Understanding innate immunity and inflammation in acne: Implications for management

    Dreno, B., Gollnick, H. P. M., Kang, S., Thiboutot, D., Bettoli, V., Torres, V. & Leyden, J., Jun 1 2015, In : Journal of the European Academy of Dermatology and Venereology. 29, S4, p. 3-11 9 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Innate Immunity
    Inflammation
    Propionibacterium acnes
    Retinoids
    2014
    50 Citations (Scopus)

    Antibiotic stewardship in dermatology: Limiting antibiotic use in acne

    Dreno, B., Thiboutot, D., Gollnick, H., Bettoli, V., Kang, S., Leyden, J. J., Shalita, A. & Torres, V., Jan 1 2014, In : European Journal of Dermatology. 24, 3, p. 330-334 5 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Dermatology
    Anti-Bacterial Agents
    Therapeutics
    Benzoyl Peroxide
    26 Citations (Scopus)
    Cost Savings
    Acne Vulgaris
    Anti-Bacterial Agents
    Retinoids
    Therapeutics
    38 Citations (Scopus)

    Consensus recommendations from the American Acne & Rosacea Society on the Management of Rosacea, Part 3: A status report on systemic therapies

    Del Rosso, J. Q., Thiboutot, D., Gallo, R., Webster, G., Tanghetti, E., Eichenfield, L. F., Stein-Gold, L., Berson, D. & Zaenglein, A., Jan 1 2014, In : Cutis. 93, 1, p. 18-28 11 p.

    Research output: Contribution to journalArticle

    Rosacea
    Acne Vulgaris
    Therapeutics
    Capsules
    Tetracyclines
    35 Citations (Scopus)

    Consensus recommendations from the american acne & rosacea society on the management of rosacea, Part 4: A status report on physical modalities and devices

    Tanghetti, E., Del Rosso, J. Q., Thiboutot, D., Gallo, R., Webster, G., Eichenfield, L. F., Stein-Gold, L., Berson, D. & Zaenglein, A., Jan 1 2014, In : Cutis. 93, 2, p. 71-76 6 p.

    Research output: Contribution to journalArticle

    Rosacea
    Acne Vulgaris
    Equipment and Supplies
    Erythema
    Telangiectasis
    41 Citations (Scopus)

    Consensus recommendations from the American Acne & Rosacea society on the management of rosacea, part 5: A guide on the management of rosacea

    Del Rosso, J. Q., Thiboutot, D., Gallo, R., Webster, G., Tanghetti, E., Eichenfield, L. F., Stein-Gold, L., Berson, D. & Zaenglein, A., Jan 1 2014, In : Cutis. 93, 3, p. 134-138 5 p.

    Research output: Contribution to journalArticle

    Rosacea
    Acne Vulgaris
    Erythema
    Signs and Symptoms
    Skin
    23 Citations (Scopus)

    IL-17: A key player in the P. acnes inflammatory cascade?

    Thiboutot, D. M., Layton, A. M. & Eady, E. A., Jan 1 2014, In : Journal of Investigative Dermatology. 134, 2, p. 307-310 4 p.

    Research output: Contribution to journalComment/debate

    Interleukin-17
    Acne Vulgaris
    Microbial Interactions
    Propionibacterium acnes
    Skin Diseases
    14 Citations (Scopus)

    Inflammasome activation by propionibacterium acnes: The story of il-1 in acne continues to unfold

    Thiboutot, D. M., Jan 1 2014, In : Journal of Investigative Dermatology. 134, 3, p. 595-597 3 p.

    Research output: Contribution to journalComment/debate

    Inflammasomes
    Propionibacterium acnes
    Acne Vulgaris
    Interleukin-1
    Chemical activation
    2013
    18 Citations (Scopus)

    A call to limit antibiotic use in acne

    Thiboutot, D., Dreno, B., Gollnick, H., Bettoli, V., Kang, S., Leyden, J. J., Shalita, A. & Torres, V., Dec 2013, In : Journal of Drugs in Dermatology. 12, 12, p. 1331 1 p.

    Research output: Contribution to journalEditorial

    Bacterial Drug Resistance
    Physicians' Practice Patterns
    Acne Vulgaris
    Dermatology
    Anti-Bacterial Agents
    30 Citations (Scopus)

    An evaluation of potential correlations between pathophysiologic mechanisms, clinical manifestations, and management of rosacea

    Del Rosso, J. Q., Gallo, R. L., Tanghetti, E., Webster, G. & Thiboutot, D., Mar 1 2013, In : Cutis. 91, 3, p. 1-8 8 p.

    Research output: Contribution to journalReview article

    Rosacea
    Facial Dermatoses
    Acne Vulgaris
    10 Citations (Scopus)

    A phase IV, open-label study evaluating the use of triple-combination therapy with minocycline HCl extended-release tablets, a topical antibiotic/retinoid preparation and benzoyl peroxide in patients with moderate to severe acne vulgaris

    Zaenglein, A. L., Shamban, A., Webster, G., Del Rosso, J., Dover, J. S., Swinyer, L., Stein, L., Lin, X., Draelos, Z., Gold, M. & Thiboutot, D., Jun 1 2013, In : Journal of Drugs in Dermatology. 12, 6, p. 619-625 7 p.

    Research output: Contribution to journalArticle

    Benzoyl Peroxide
    Minocycline
    Retinoids
    Acne Vulgaris
    Tablets
    52 Citations (Scopus)

    Consensus recommendations from the American Acne & Rosacea Society on the management of rosacea, Part 1: A status report on the disease state, general measures, and adjunctive skin care

    Del Rosso, J. Q., Thiboutot, D., Gallo, R., Webster, G., Tanghetti, E., Eichenfield, L., Stein-Gold, L., Berson, D. & Zaenglein, A., Nov 1 2013, In : Cutis. 92, 5, p. 234-240 7 p.

    Research output: Contribution to journalArticle

    Rosacea
    Skin Care
    Acne Vulgaris
    Skin
    Signs and Symptoms
    40 Citations (Scopus)

    Consensus recommendations from the american acne and rosacea society on the management of rosacea, part 2: A status report on topical agents

    Del Rosso, J. Q., Thiboutot, D., Gallo, R., Webster, G., Tanghetti, E., Eichenfield, L., Stein-Gold, L., Berson, D. & Zaenglein, A., Dec 1 2013, In : Cutis. 92, 6, p. 277-284 8 p.

    Research output: Contribution to journalArticle

    Rosacea
    Skin Care
    Therapeutics
    United States Food and Drug Administration
    30 Citations (Scopus)

    Emerging therapies in rosacea

    Layton, A. & Thiboutot, D., Dec 1 2013, In : Journal of the American Academy of Dermatology. 69, 6 SUPPL.1

    Research output: Contribution to journalArticle

    Rosacea
    Doxycycline
    Therapeutics
    Skin
    Research