Diane Thiboutot, MD

    • 8938 Citations
    • 51 h-Index
    1990 …2019
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    Research Output 1990 2019

    2008
    175 Citations (Scopus)

    Thematic review series: Skin Lipids. Sebaceous gland lipids: Friend or foe?

    Smith, K. R. & Thiboutot, D. M., Feb 1 2008, In : Journal of Lipid Research. 49, 2, p. 271-281 11 p.

    Research output: Contribution to journalReview article

    Sebaceous Glands
    Skin
    Lipids
    Squalene
    Waxes
    31 Citations (Scopus)

    Versatility of azelaic acid 15% gel in treatment of inflammatory acne vulgaris

    Thiboutot, D., Jan 2008, In : Journal of Drugs in Dermatology. 7, 1, p. 13-16 4 p.

    Research output: Contribution to journalReview article

    Acne Vulgaris
    Gels
    Benzoyl Peroxide
    Therapeutics
    Clindamycin
    2007
    146 Citations (Scopus)

    Adapalene-benzoyl peroxide, a fixed-dose combination for the treatment of acne vulgaris: Results of a multicenter, randomized double-blind, controlled study

    Thiboutot, D. M., Weiss, J., Bucko, A., Eichenfield, L., Jones, T., Clark, S., Liu, Y., Graeber, M. & Kang, S., Nov 1 2007, In : Journal of the American Academy of Dermatology. 57, 5, p. 791-799 9 p.

    Research output: Contribution to journalArticle

    Benzoyl Peroxide
    Acne Vulgaris
    Double-Blind Method
    Gels
    Adapalene
    26 Citations (Scopus)

    A double-blinded, randomized, vehicle-controlled, multicenter, parallel-group study to assess the safety and efficacy of tretinoin gel microsphere 0.04% in the treatment of acne vulgaris in adults

    Berger, R., Barba, A., Fleischer, A., Leyden, J. J., Lucky, A., Pariser, D., Rafal, E., Thiboutot, D., Wilson, D., Grossman, R. & Nighland, M., Aug 1 2007, In : Cutis. 80, 2, p. 152-157 6 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Tretinoin
    Microspheres
    Gels
    Safety
    351 Citations (Scopus)

    Guidelines of care for acne vulgaris management

    Strauss, J. S., Krowchuk, D. P., Leyden, J. J., Lucky, A. W., Shalita, A. R., Siegfried, E. C., Thiboutot, D. M., Van Voorhees, A. S., Beutner, K. A., Sieck, C. K. & Bhushan, R., Apr 1 2007, In : Journal of the American Academy of Dermatology. 56, 4, p. 651-663 13 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Guidelines
    Guideline Adherence
    Physicians
    Therapeutics
    2 Citations (Scopus)

    Hormonal influences in acne

    Thiboutot, D., Jan 1 2007, Acne and its Therapy. CRC Press, p. 83-95 13 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Acne Vulgaris
    Hormones
    Sebaceous Glands
    Dehydroepiandrosterone Sulfate
    Dihydrotestosterone
    Dermatologic Agents
    Benzoyl Peroxide
    Conflict of Interest
    Drug Costs
    Retinoids
    37 Citations (Scopus)

    Pharmacokinetics of dapsone Gel, 5% for the treatment of acne vulgaris

    Thiboutot, D. M., Willmer, J., Sharata, H., Halder, R. & Garrett, S., Aug 9 2007, In : Clinical Pharmacokinetics. 46, 8, p. 697-712 16 p.

    Research output: Contribution to journalArticle

    Dapsone
    Acne Vulgaris
    Pharmacokinetics
    Gels
    Sulfamethoxazole Drug Combination Trimethoprim
    25 Citations (Scopus)

    Pharmacologic Modulation of Sebaceous Gland Activity: Mechanisms and Clinical Applications

    Clarke, S. B., Nelson, A. M., George, R. E. & Thiboutot, D. M., Apr 1 2007, In : Dermatologic Clinics. 25, 2, p. 137-146 10 p.

    Research output: Contribution to journalReview article

    Sebaceous Glands
    Acne Vulgaris
    Retinoids
    Sebum
    Therapeutics
    2006
    108 Citations (Scopus)

    13-cis retinoic acid induces apoptosis and cell cycle arrest in human SEB-1 sebocytes

    Nelson, A. M., Gilliland, K. L., Cong, Z. & Thiboutot, D. M., Oct 30 2006, In : Journal of Investigative Dermatology. 126, 10, p. 2178-2189 12 p.

    Research output: Contribution to journalArticle

    Isotretinoin
    Cell Cycle Checkpoints
    Cells
    Apoptosis
    Retinoids
    15 Citations (Scopus)

    A clinical overview of azelaic acid

    Elewski, B. & Thiboutot, D., Feb 1 2006, In : Cutis. 77, 2 SUPPL., p. 12-16 5 p.

    Research output: Contribution to journalReview article

    Rosacea
    Gels
    Metronidazole
    azelaic acid
    85 Citations (Scopus)

    Adapalene gel, 0.1%, as maintenance therapy for acne vulgaris: A randomized, controlled, investigator-blind follow-up of a recent combination study

    Thiboutot, D. M., Shalita, A. R., Yamauchi, P. S., Dawson, C., Kerrouche, N., Arsonnaud, S. & Kang, S., May 1 2006, In : Archives of dermatology. 142, 5, p. 597-602 6 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Gels
    Research Personnel
    Doxycycline
    Maintenance
    69 Citations (Scopus)

    Adapalene gel 0.3% for the treatment of acne vulgaris: A multicenter, randomized, double-blind, controlled, phase III trial

    Thiboutot, D., Pariser, D. M., Egan, N., Flores, J., Herndon, J. H., Kanof, N. B., Kempers, S. E., Maddin, S., Poulin, Y. P., Wilson, D. C., Hwa, J., Liu, Y. & Graeber, M., Feb 1 2006, In : Journal of the American Academy of Dermatology. 54, 2, p. 242-250 9 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Gels
    Therapeutics
    Adapalene
    Random Allocation
    14 Citations (Scopus)

    Azelaic acid gel 15%: Clinical versatility in the treatment of rosacea

    Del Rosso, J. Q., Baum, E. W., Draelos, Z. D., Elewski, B. E., Fleischer, A. B., Kakita, L. S. & Thiboutot, D., Nov 1 2006, In : Cutis. 78, 5 SUPPL., p. 6-19 14 p.

    Research output: Contribution to journalReview article

    Rosacea
    Gels
    Therapeutics
    Skin Care
    Compliance
    59 Citations (Scopus)

    Comparison of tazarotene and minocycline maintenance therapies in acne vulgaris: A multicenter, double-blind, randomized, parallel-group study

    Leyden, J., Thiboutot, D. M., Shalita, A. R., Webster, G., Washenik, K., Strober, B. E. & Shupack, J., May 1 2006, In : Archives of dermatology. 142, 5, p. 605-612 8 p.

    Research output: Contribution to journalArticle

    Minocycline
    Acne Vulgaris
    Maintenance
    Capsules
    Gels
    88 Citations (Scopus)

    Expert committee recommendations for acne management

    Zaenglein, A. L. & Thiboutot, D. M., Sep 1 2006, In : Pediatrics. 118, 3, p. 1188-1199 12 p.

    Research output: Contribution to journalReview article

    Acne Vulgaris
    Retinoids
    Therapeutics
    Guidelines
    Anti-Infective Agents
    120 Citations (Scopus)

    Gene array expression profiling in acne lesions reveals marked upregulation of genes involved in inflammation and matrix remodeling

    Trivedi, N. R., Gilliland, K. L., Zhao, W., Liu, W. & Thiboutot, D. M., Jan 1 2006, In : Journal of Investigative Dermatology. 126, 5, p. 1071-1079 9 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Gene Expression Profiling
    Skin
    Up-Regulation
    Genes
    78 Citations (Scopus)

    Insulin-like growth factor-1 induces lipid production in human SEB-1 sebocytes via sterol response element-binding protein-1

    Smith, T. M., Cong, Z., Gilliland, K. L., Clawson, G. A. & Thiboutot, D. M., Jun 1 2006, In : Journal of Investigative Dermatology. 126, 6, p. 1226-1232 7 p.

    Research output: Contribution to journalArticle

    Response Elements
    Somatomedins
    Sterols
    Lipogenesis
    Carrier Proteins
    4 Citations (Scopus)

    Ipledge: A report from the front lines of dermatologic practice

    Cockerell, C. J. & Thiboutot, D., Jan 1 2006, In : Virtual Mentor. 8, 8, p. 524-528 5 p.

    Research output: Contribution to journalReview article

    122 Citations (Scopus)

    Peroxisome proliferator-activated receptors increase human sebum production

    Trivedi, N. R., Cong, Z., Nelson, A. M., Albert, A. J., Rosamilia, L. L., Sivarajah, S., Gilliland, K. L., Liu, W., Mauger, D. T., Gabbay, R. A. & Thiboutot, D. M., Sep 1 2006, In : Journal of Investigative Dermatology. 126, 9, p. 2002-2009 8 p.

    Research output: Contribution to journalArticle

    Sebum
    Peroxisome Proliferator-Activated Receptors
    Isotretinoin
    Lipogenesis
    rosiglitazone
    18 Citations (Scopus)

    Treatment considerations for inflammatory acne: clinical evidence for adapalene 0.1% in combination therapies.

    Thiboutot, D. M. & Gollnick, H. P., Sep 2006, In : Journal of Drugs in Dermatology. 5, 8, p. 785-794 10 p.

    Research output: Contribution to journalReview article

    Acne Vulgaris
    Retinoids
    Therapeutics
    Benzoyl Peroxide
    Sebum
    2005
    66 Citations (Scopus)

    Combination therapy with adapalene gel 0.1% and doxycycline for severe acne vulgaris: a multicenter, investigator-blind, randomized, controlled study.

    Thiboutot, D. M., Shalita, A. R., Yamauchi, P. S., Dawson, C., Arsonnaud, S. & Kang, S., Jan 1 2005, In : Skinmed. 4, 3, p. 138-146 9 p.

    Research output: Contribution to journalArticle

    Doxycycline
    Acne Vulgaris
    Gels
    Research Personnel
    Anti-Bacterial Agents
    122 Citations (Scopus)
    Dehydroepiandrosterone Sulfate
    Dihydrotestosterone
    Acne Vulgaris
    Somatomedins
    Serum
    10 Citations (Scopus)

    Diagnosing and managing the patient with rosacea

    Mackley, C. L. & Thiboutot, D. M., Apr 1 2005, In : Cutis. 75, 4 SUPPL., p. 25-29 5 p.

    Research output: Contribution to journalReview article

    Rosacea
    Facial Dermatoses
    Skin Care
    Laser Therapy
    Cosmetics
    38 Citations (Scopus)

    The efficacy and safety of adapalene gel 0.3% in the treatment of acne vulgaris: A randomized, multicenter, investigator-blinded, controlled comparison study versus adapalene gel 0.1% and vehicle

    Pariser, D. M., Thiboutot, D. M., Clark, S. D., Jones, T. M., Liu, Y. & Graeber, M., Aug 1 2005, In : Cutis. 76, 2, p. 145-151 7 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Gels
    Research Personnel
    Safety
    Adapalene
    46 Citations (Scopus)

    Topical retinoids in inflammatory acne: A retrospective, investigator-blinded, vehicle-controlled, photographic assessment

    Leyden, J. J., Shalita, A., Thiboutot, D., Washenik, K. & Webster, G., Jan 1 2005, In : Clinical therapeutics. 27, 2, p. 216-224 9 p.

    Research output: Contribution to journalArticle

    Retinoids
    Acne Vulgaris
    Tretinoin
    Research Personnel
    Gels
    2004
    94 Citations (Scopus)

    Acne: Hormonal concepts and therapy

    Thiboutot, D., Jan 1 2004, In : Clinics in Dermatology. 22, 5, p. 419-428 10 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Hormones
    Sebaceous Glands
    Therapeutics
    Dehydroepiandrosterone Sulfate

    Acné: 1991-2001

    Translated title of the contribution: Acne: 1991-2001Thiboutot, D., Jan 1 2004, In : EMC - Dermatologie-Cosmetologie. 1, 4, p. 188-198 11 p.

    Research output: Contribution to journalShort survey

    Acne Vulgaris
    73 Citations (Scopus)

    American Academy of Dermatology Consensus Conference on the safe and optimal use of isotretinoin: Summary and recommendations

    Goldsmith, L. A., Bolognia, J. L., Callen, J. P., Chen, S. C., Feldman, S. R., Lim, H. W., Lucky, A. W., Reed, B. R., Siegfried, E. C., Thiboutot, D. M. & Wheeland, R. G., Jan 1 2004, In : Journal of the American Academy of Dermatology. 50, 6, p. 900-906 7 p.

    Research output: Contribution to journalArticle

    Isotretinoin
    35 Citations (Scopus)

    A systemic type I 5 α-reductase inhibitor is ineffective in the treatment of acne vulgaris

    Leyden, J., Bergfeld, W., Drake, L., Dunlap, F., Goldman, M. P., Gottlieb, A. B., Heffernan, M. P., Hickman, J. G., Hordinsky, M., Jarrett, M., Kang, S., Lucky, A., Peck, G., Phillips, T., Rapaport, M., Roberts, J., Savin, R., Sawaya, M. E., Shalita, A., Shavin, J. & 14 others, Shaw, J. C., Stein, L., Stewart, D., Strauss, J., Swinehart, J., Swinyer, L., Thiboutot, D., Washenik, K., Weinstein, G., Whiting, D., Pappas, F., Sanchez, M., Terranella, L. & Waldstreicher, J., Jan 1 2004, In : Journal of the American Academy of Dermatology. 50, 3, p. 443-447 5 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Sebaceous Glands
    Oxidoreductases
    Minocycline
    Androgens
    28 Citations (Scopus)

    Effects of tazarotene 0.1% cream in the treatment of facial acne vulgaris: Pooled results from two multicenter, double-blind, randomized, vehicle-controlled, parallel-group trials

    Shalita, A. R., Berson, D. S., Thiboutot, D. M., Leyden, J. J., Parizadeh, D., Sefton, J., Walker, P. S. & Gibson, J. R., Nov 1 2004, In : Clinical therapeutics. 26, 11, p. 1865-1873 9 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Retinoids
    Skin
    Therapeutics
    Drug Monitoring
    2 Citations (Scopus)

    Erratum: American Academy of Dermatology Consensus Conference on the Safe and Optional Use of Isotredtinoin: Summary and recommendations (Journal of the American Academy of Dermatology (June 2004) 51 (900-906))

    Goldsmith, L. A., Bolognia, J. L., Callen, J. P., Chen, S. C., Feldman, S. R., Lim, H. W., Lucky, A. W., Reed, B. R., Siegfried, E. C., Thiboutot, D. M. & Wheeland, R. G., Sep 1 2004, In : Journal of the American Academy of Dermatology. 51, 3, 1 p.

    Research output: Contribution to journalComment/debate

    14 Citations (Scopus)

    Inhibition of papilloma progression by antisense oligonucleotides targeted to HPV11 E6/E7 RNA

    Clawson, G. A., Miranda, G. Q., Sivarajah, A., Xin, P., Pan, W., Thiboutot, D. & Christensen, N. D., Sep 1 2004, In : Gene Therapy. 11, 17, p. 1331-1341 11 p.

    Research output: Contribution to journalArticle

    Antisense Oligonucleotides
    Papilloma
    RNA
    In Situ Hybridization
    Catalytic DNA
    19 Citations (Scopus)

    Photographic review of results from a clinical study comparing benzoyl peroxide 5%/clindamycin 1% topical gel with vehicle in the treatment of rosacea

    Leyden, J. J., Thiboutot, D. & Shalita, A., Jun 1 2004, In : Cutis. 73, 6 SUPPL., p. 11-17 7 p.

    Research output: Contribution to journalReview article

    Benzoyl Peroxide
    Rosacea
    Clindamycin
    Gels
    Therapeutics
    105 Citations (Scopus)

    Regulation of human sebaceous glands

    Thiboutot, D., Jan 1 2004, In : Journal of Investigative Dermatology. 123, 1, p. 1-12 12 p.

    Research output: Contribution to journalReview article

    2003

    Editorial: Current and future aspects on acne

    Zouboulis, C. C., Herane, M. I. & Thiboutot, D., Jan 1 2003, In : Dermatology. 206, 1, 1 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    128 Citations (Scopus)
    Rosacea
    Gels
    Safety
    Therapeutics
    Patient Selection
    59 Citations (Scopus)
    Multiple Hamartoma Syndrome
    Skin Manifestations
    Polyps
    Esophagus
    Mutation
    201 Citations (Scopus)
    Sebaceous Glands
    Steroidogenic Factor 1
    Coenzymes
    Epidermis
    Skin
    702 Citations (Scopus)

    Management of acne: A report from a global alliance to improve outcomes in acne

    Gollnick, H., Cunliffe, W., Berson, D., Dreno, B., Finlay, A., Leyden, J. J., Shalita, A. R., Thiboutot, D. & Schwarz, T., Jul 1 2003, In : Journal of the American Academy of Dermatology. 49, 1 SUPPL.

    Research output: Contribution to journalArticle

    Topical Administration
    International Cooperation
    Pregnancy Complications
    Retinoids
    Acne Vulgaris
    67 Citations (Scopus)

    Pathogenesis of acne: Recent research advances

    Harper, J. C., Thiboutot, D. M. & Yancey, K. B., Dec 1 2003, In : Advances in dermatology. 19, p. 1-10 10 p.

    Research output: Contribution to journalReview article

    Acne Vulgaris
    Research
    Isotretinoin
    Sebum
    Skin Diseases

    The acne challenge: Management in an age of bacterial resistance

    Leyden, J. J., Eichenfield, L. F., Graham, D. R., Shalita, A. R. & Thiboutot, D., Jan 15 2003, In : Medical Crossfire. 5, 1, p. 30-44 15 p.

    Research output: Contribution to journalReview article

    Acne Vulgaris
    Propionibacterium acnes
    Dermatology
    Anti-Bacterial Agents
    Skin Diseases
    90 Citations (Scopus)

    Update and future of hormonal therapy in acne

    Thiboutot, D. & Chen, W., Feb 12 2003, In : Dermatology. 206, 1, p. 57-67 11 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Flutamide
    Cyproterone Acetate
    Sebaceous Glands
    Androgen Antagonists
    2002
    16 Citations (Scopus)

    Acne: 1991-2001.

    Thiboutot, D., Jan 1 2002, In : Journal of the American Academy of Dermatology. 47, 1, p. 109-117 9 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    11 Citations (Scopus)

    A randomized, parallel, vehicle-controlled comparison of two erythromycin/benzoyl peroxide preparations for acne vulgaris

    Thiboutot, D., Jarratt, M., Rich, P., Rist, T., Rodriguez, D. & Levy, S., Jan 1 2002, In : Clinical therapeutics. 24, 5, p. 773-785 13 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Therapeutics
    Physicians
    erythromycin drug combination benzoyl peroxide
    Refrigeration
    193 Citations (Scopus)

    Cutaneous androgen metabolism: Basic research and clinical perspectives

    Chen, W. C., Thiboutot, D. & Zouboulis, C. C., Jan 1 2002, In : Journal of Investigative Dermatology. 119, 5, p. 992-1007 16 p.

    Research output: Contribution to journalReview article

    Sebaceous Glands
    3-Hydroxysteroid Dehydrogenases
    Metabolism
    Hair Follicle
    Androgens
    46 Citations (Scopus)

    Diet and acne revisited

    Thiboutot, D. M. & Strauss, J. S., Dec 1 2002, In : Archives of Dermatology. 138, 12, p. 1591-1592 2 p.

    Research output: Contribution to journalEditorial

    Paraguay
    Papua New Guinea
    Sex Distribution
    Age Distribution
    Acne Vulgaris
    2001
    90 Citations (Scopus)

    A randomized, controlled trial of a low-dose contraceptive containing 20 μg of ethinyl estradiol and 100 μg of levonorgestrel for acne treatment

    Thiboutot, D., Archer, D. F., Lemay, A., Washenik, K., Roberts, J. & Harrison, D. D., Sep 3 2001, In : Fertility and sterility. 76, 3, p. 461-468 8 p.

    Research output: Contribution to journalArticle

    Levonorgestrel
    Ethinyl Estradiol
    Acne Vulgaris
    Contraceptive Agents
    Randomized Controlled Trials
    28 Citations (Scopus)
    Acne Vulgaris
    Therapeutics
    Anti-Bacterial Agents
    Retinoids
    Oral Contraceptives
    88 Citations (Scopus)

    Health-related quality of life among patients with facial acne - Assessment of a new acne-specific questionnaire

    Martin, A. R., Lookingbill, D. P., Botek, A., Light, J., Thiboutot, D. & Girman, C. J., Sep 27 2001, In : Clinical and Experimental Dermatology. 26, 5, p. 380-385 6 p.

    Research output: Contribution to journalArticle

    Acne Vulgaris
    Quality of Life
    Clinical Trials
    Surveys and Questionnaires
    Therapeutic Uses