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Fingerprint Dive into the research topics where Edward Gunther is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Breast Medicine & Life Sciences
Transgenic Mice Medicine & Life Sciences
Ficusin Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Human Mammary Glands Medicine & Life Sciences
Mutagenesis Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences

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Projects 1999 2022

Breast Neoplasms
Oncogenes
Breast
Neoplasm Genes
Genetic Association Studies
Secondary Prevention
Breast Neoplasms
Neoplasms
Recurrence
Tumor Escape
Residual Neoplasm
Breast Neoplasms
Therapeutics
Recurrence
Neoplasms
Transgenes
Breast
Epithelial Cells
Transgenic Mice
Down-Regulation

Research Output 1993 2019

  • 1762 Citations
  • 19 h-Index
  • 26 Article
  • 1 Review article
1 Citation (Scopus)

Evolution of Relapse-Proficient Subclones Constrained by Collateral Sensitivity to Oncogene Overdose in Wnt-Driven Mammary Cancer

Keller, R. R. & Gunther, E., Jan 22 2019, In : Cell Reports. 26, 4, p. 893-905.e4

Research output: Contribution to journalArticle

Clonal Evolution
Oncogenes
Breast Neoplasms
Recurrence
Mutation
2 Citations (Scopus)

Carcinogen-specific mutations in preferred Ras-Raf pathway oncogenes directed by strand bias

Keller, R. R., Gestl, S. A., Lu, A. Q., Hoke, A., Feith, D. J. & Gunther, E., Aug 1 2016, In : Carcinogenesis. 37, 8, p. 810-816 7 p.

Research output: Contribution to journalArticle

Oncogenes
Carcinogens
Mutation
Ethylnitrosourea
9,10-Dimethyl-1,2-benzanthracene
184 Citations (Scopus)

Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

Cleary, A. S., Leonard, T. L., Gestl, S. A. & Gunther, E., Jan 1 2014, In : Nature. 508, 1, p. 113-117 5 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Neoplasms
Carcinogenesis
Recurrence
Wnt Signaling Pathway
1 Citation (Scopus)

Basal but not luminal mammary epithelial cells require PI3K/mTOR signaling for Ras-driven overgrowth

Plichta, K. A., Mathers, J. L., Gestl, S. A., Glick, A. B. & Gunther, E., Nov 15 2012, In : Cancer Research. 72, 22, p. 5856-5866 11 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Breast
Epithelial Cells
Organoids
Human Mammary Glands
15 Citations (Scopus)

A BAC transgenic reporter recapitulates in vivo regulation of human telomerase reverse transcriptase in development and tumorigenesis

Jia, W., Wang, S., Horner, J. W., Wang, N., Wang, H., Gunther, E., De Pinho, R. A. & Zhu, J., Mar 1 2011, In : FASEB Journal. 25, 3, p. 979-989 11 p.

Research output: Contribution to journalArticle

Bacterial Artificial Chromosomes
Chromosomes
Renilla Luciferases
Transcription
Carcinogenesis