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Dive into the research topics where Edward P. O'Brien, Jr. is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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MoCeIS-DCL: Planning Workshops for Synthesis of Massively Parallel Assays and Molecular Physiology
O'Brien, Jr., E. P., Lareau, L. L., Marqusee, S. S., Shah, P. P. & Thirumalai, D. D.
9/1/21 → 8/31/22
Project: Research project
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Machine Learning Guided Biophysical Model Development of Amino Acid and tRNA Effects on Translation-Elongation Speed
1/1/21 → 12/31/23
Project: Research project
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CC* Team: Research Innovation with Scientists and Engineers (RISE)
Hanna, C. C., O'Brien, Jr., E. P. & Evans, J.
7/1/20 → 6/30/23
Project: Research project
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Conference: Protein Folding on the Ribosome
O'Brien, Jr., E. P. & Kaiser, C. C.
8/1/20 → 7/31/22
Project: Research project
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CONFERENCE: Protein Folding on the Ribosome; December 14-16, 2019; Berlin, Germany
8/1/19 → 7/31/20
Project: Research project
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A pan-CRISPR analysis of mammalian cell specificity identifies ultra-compact sgRNA subsets for genome-scale experiments
Zhao, B., Rao, Y., Leighow, S., O’Brien, E. P., Gilbert, L. & Pritchard, J. R., Dec 2022, In: Nature communications. 13, 1, 625.Research output: Contribution to journal › Article › peer-review
Open Access -
Cocktail of REGN Antibodies Binds More Strongly to SARS-CoV-2 Than Its Components, but the Omicron Variant Reduces Its Neutralizing Ability
Nguyen, H., Lan, P. D., Nissley, D. A., O'Brien, E. P. & Li, M. S., Apr 21 2022, In: Journal of Physical Chemistry B. 126, 15, p. 2812-2823 12 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Erratum: Ribosome Elongation Kinetics of Consecutively Charged Residues Are Coupled to Electrostatic Force (Biochemistry (2021) 60:43 (3223−3235) DOI:10.1021/acs.biochem.1c00507)
Leininger, S. E., Rodriguez, J., Vu, Q. V., Jiang, Y., Li, M. S., Deutsch, C. & O’Brien, E. P., Jan 18 2022, In: Biochemistry. 61, 2, p. 125 1 p.Research output: Contribution to journal › Comment/debate › peer-review
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Combinations of slow-translating codon clusters can increase mRNA half-life in Saccharomyces cerevisiae
Sharma, A. K., Venezian, J., Shiber, A., Kramer, G., Bukau, B. & O’Brien, E. P., Dec 21 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 51, e2026362118.Research output: Contribution to journal › Article › peer-review
Open Access -
Electrostatic Interactions Explain the Higher Binding Affinity of the CR3022 Antibody for SARS-CoV-2 than the 4A8 Antibody
Nguyen, H., Lan, P. D., Nissley, D. A., O'Brien, E. P. & Li, M. S., Jul 15 2021, In: Journal of Physical Chemistry B. 125, 27, p. 7368-7379 12 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations