Photo of Edward P. O'Brien, Jr.
Contact Expert

View Scopus Profile

Edward P. O'Brien, Jr., PhD

    • 1722 Citations
    • 24 h-Index
    20002020

    Research output per year

    If you made any changes in Pure these will be visible here soon.

    Fingerprint Dive into the research topics where Edward P. O'Brien, Jr. is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects

    Modeling the influence of translation-elongation kinetics on protein structure and function

    O'Brien, Jr., E. P.

    National Institute of General Medical Sciences

    8/1/17 → 7/31/18

    Project: Research project

    • Research Output

    • 1722 Citations
    • 24 h-Index
    • 40 Article
    • 5 Review article
    • 1 Comment/debate

    Electrostatic Interactions Govern Extreme Nascent Protein Ejection Times from Ribosomes and Can Delay Ribosome Recycling

    Nissley, D. A., Vu, Q. V., Trovato, F., Ahmed, N., Jiang, Y., Li, M. S. & O'Brien, E. P., Apr 1 2020, In : Journal of the American Chemical Society. 142, 13, p. 6103-6110 8 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Forcing the ribosome to change its message

    Leininger, S. E., Deutsch, C. & O’Brien, E. P., May 15 2020, In : Journal of Biological Chemistry. 295, 20, p. 6809-6810 2 p.

    Research output: Contribution to journal › Review article

    Open Access

    • Hierarchical Markov State Model Building to Describe Molecular Processes

    Wolfe, D. K., Persichetti, J. R., Sharma, A. K., Hudson, P. S., Woodcock, H. L. & O'brien, E. P., Mar 10 2020, In : Journal of Chemical Theory and Computation. 16, 3, p. 1816-1826 11 p.

    Research output: Contribution to journal › Article

    • A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data

    Sharma, A. K., Sormanni, P., Ahmed, N., Ciryam, P., Friedrich, U. A., Kramer, G. & O'Brien, E. P., 2019, In : PLoS computational biology. 15, 5, e1007070.

    Research output: Contribution to journal › Article

    Open Access
    • 7 Scopus citations

    Domain topology, stability, and translation speed determine mechanical force generation on the ribosome

    Leininger, S. E., Trovato, F., Nissley, D. A. & O’Brien, E. P., 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 12, p. 5523-5532 10 p.

    Research output: Contribution to journal › Article

    • 8 Scopus citations