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Fingerprint Dive into the research topics where Edward P. O'Brien, Jr. is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Protein Folding Medicine & Life Sciences
Protein folding Chemical Compounds
Ribosomes Medicine & Life Sciences
Proteins Chemical Compounds
Codon Medicine & Life Sciences
proteins Physics & Astronomy
folding Physics & Astronomy
Tunnels Chemical Compounds

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Research Output 2000 2019

  • 1548 Citations
  • 24 h-Index
  • 38 Article
  • 4 Review article
  • 1 Comment/debate
2 Citations (Scopus)

A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data

Sharma, A. K., Sormanni, P., Ahmed, N., Ciryam, P., Friedrich, U. A., Kramer, G. & O'Brien, E. P., Jan 1 2019, In : PLoS computational biology. 15, 5, e1007070.

Research output: Contribution to journalArticle

Open Access
Chemical Kinetics
Stem cells
2 Citations (Scopus)

Domain topology, stability, and translation speed determine mechanical force generation on the ribosome

Leininger, S. E., Trovato, F., Nissley, D. A. & O’Brien, E. P., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 12, p. 5523-5532 10 p.

Research output: Contribution to journalArticle

Statistical Models
1 Citation (Scopus)

Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming

Ahmed, N., Sormanni, P., Ciryam, P., Vendruscolo, M., Dobson, C. M. & O’Brien, E. P., Dec 1 2019, In : Scientific reports. 9, 1, 6256.

Research output: Contribution to journalArticle

Open Access
Messenger RNA
Reading Frames
1 Citation (Scopus)

Mechanochemistry in Translation

Leininger, S. E., Narayan, K., Deutsch, C. & O'Brien, E. P., Nov 26 2019, In : Biochemistry. 58, 47, p. 4657-4666 10 p.

Research output: Contribution to journalReview article

Peptidyl Transferases
Protein folding
Protein Folding
3 Citations (Scopus)
protein synthesis
Protein Synthesis