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Fingerprint Dive into the research topics where Edward P. O'Brien, Jr. is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Protein folding Chemical Compounds
Protein Folding Medicine & Life Sciences
Ribosomes Medicine & Life Sciences
Proteins Chemical Compounds
Codon Medicine & Life Sciences
proteins Physics & Astronomy
folding Physics & Astronomy
Tunnels Chemical Compounds

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Research Output 2000 2019

  • 1477 Citations
  • 23 h-Index
  • 39 Article
  • 3 Review article
  • 1 Comment/debate
1 Citation (Scopus)

A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data

Sharma, A. K., Sormanni, P., Ahmed, N., Ciryam, P., Friedrich, U. A., Kramer, G. & O'Brien, Jr., E. P., May 1 2019, In : PLoS computational biology. 15, 5, p. e1007070

Research output: Contribution to journalArticle

Open Access
Chemical Kinetics
Elongation
Profiling
ribosomes
Stem cells
1 Citation (Scopus)

Domain topology, stability, and translation speed determine mechanical force generation on the ribosome

Leininger, S. E., Trovato, F., Nissley, D. A. & O'Brien, Jr., E. P., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 12, p. 5523-5532 10 p.

Research output: Contribution to journalArticle

Ribosomes
Proteins
Statistical Models
Proteome
Phenotype

Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer Programming

Ahmed, N., Sormanni, P., Ciryam, P., Vendruscolo, M., Dobson, C. M. & O'Brien, Jr., E. P., Dec 1 2019, In : Scientific reports. 9, 1, 6256.

Research output: Contribution to journalArticle

Open Access
Ribosomes
Messenger RNA
Codon
Camellia
Reading Frames

Mechanochemistry in Translation

Leininger, S. E., Narayan, K., Deutsch, C. & O'Brien, Jr., E. P., Jan 1 2019, In : Biochemistry.

Research output: Contribution to journalArticle

Peptidyl Transferases
Protein folding
Protein Folding
Ribosomes
Tunnels
2 Citations (Scopus)
protein synthesis
Protein Synthesis
determinants
Determinant
Scaling