• 640 Citations
  • 13 h-Index
20072019

Research output per year

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Personal profile

Research interests

Dr. Elizabeth Proctor’s laboratory aims to characterize the systems biology of neurodegenerative disease at multiple scales (molecular, cellular, tissue, and physiological), with the ultimate goal of providing tools for early diagnosis and identifying novel preventative and therapeutic strategies. Her laboratory combines multiplexing experiments with computational modeling and machine learning to identify patterns associated with neurodegenerative disease pathology, then manipulates the identified variables in cell culture and/or in animal models to test their ability to alter and control disease state.

Education/Academic qualification

Postdoctoral Fellowship, Massachusetts Institute of Technology

… → 2018

PhD, University of North Carolina at Chapel Hill

… → 2013

BS, BA, Purdue University

… → 2008

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Projects

  • Research Output

    • 640 Citations
    • 13 h-Index
    • 27 Article
    • 2 Review article
    • 1 Comment/debate

    Computational translation of genomic responses from experimental model systems to humans

    Brubaker, D. K., Proctor, E. A., Haigis, K. M. & Lauffenburger, D. A., Jan 1 2019, In : PLoS computational biology. 15, 1, e1006286.

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes

    Nicholas, D. A., Proctor, E. A., Agrawal, M., Belkina, A. C., Van Nostrand, S. C., Panneerseelan-Bharath, L., Jones, A. R., Raval, F., Ip, B. C., Zhu, M., Cacicedo, J. M., Habib, C., Sainz-Rueda, N., Persky, L., Sullivan, P. G., Corkey, B. E., Apovian, C. M., Kern, P. A., Lauffenburger, D. A. & Nikolajczyk, B. S., Sep 3 2019, In : Cell Metabolism. 30, 3, p. 447-461.e5

    Research output: Contribution to journalArticle

  • 6 Scopus citations

    β-Methylamino-L-alanine substitution of serine in SOD1 suggests a direct role in ALS etiology

    Proctor, E. A., Mowrey, D. D. & Dokholyan, N. V., Jul 2019, In : PLoS computational biology. 15, 7, e1007225.

    Research output: Contribution to journalArticle

    Open Access
  • Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis

    Fleury, M., Belkina, A. C., Proctor, E. A., Zammitti, C., Simms, R. W., Lauffenburger, D. A., Snyder-Cappione, J. E., Lafyatis, R. & Dooms, H., Apr 2018, In : Arthritis and Rheumatology. 70, 4, p. 566-577 12 p.

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator

    Wang, C., Aleksandrov, A. A., Yang, Z., Forouhar, F., Proctor, E. A., Kota, P., An, J., Kaplan, A., Khazanov, N., Boël, G., Stockwell, B. R., Senderowitz, H., Dokholyan, N. V., Riordan, J. R., Brouillette, C. G. & Hunt, J. F., Nov 16 2018, In : Journal of Biological Chemistry. 293, 46, p. 17685-17704 20 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations