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Article
2018

Exaggerated cardiovascular responses to treadmill running in rats with peripheral arterial insufficiency

Kuczmarski, J. M., Unrath, K. & Thomas, G. D., Jan 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 314, 1, p. H114-H121

Research output: Contribution to journalArticle

1 Scopus citations
2017

The role played by oxidative stress in evoking the exercise pressor reflex in health and simulated peripheral artery disease

Harms, J. E., Kuczmarski, J. M., Kim, J. S., Thomas, G. D. & Kaufman, M. P., Jul 1 2017, In : Journal of Physiology. 595, 13, p. 4365-4378 14 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Functional sympatholysis in hypertension

Thomas, G., Mar 1 2015, In : Autonomic Neuroscience: Basic and Clinical. 188, p. 64-68 5 p.

Research output: Contribution to journalArticle

13 Scopus citations
2013

Differential effects of nebivolol versus metoprolol on functional sympatholysis in hypertensive humans

Price, A., Raheja, P., Wang, Z., Arbique, D., Adams-Huet, B., Mitchell, J. H., Victor, R. G., Thomas, G. D. & Vongpatanasin, W., Apr 3 2013, In : Hypertension. 61, 6, p. 1263-1269 7 p.

Research output: Contribution to journalArticle

20 Scopus citations

Dual AAV therapy ameliorates exercise-induced muscle injury and functional ischemia in murine models of duchenne muscular dystrophy

Zhang, Y., Yue, Y., Li, L., Hakim, C. H., Zhang, K., Thomas, G. D. & Duan, D., Sep 1 2013, In : Human molecular genetics. 22, 18, p. 3720-3729 10 p., ddt224.

Research output: Contribution to journalArticle

52 Scopus citations
2012

Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate-tolerant rats and humans

Fadel, P. J., Farias, M., Gallagher, K. M., Wang, Z. & Thomas, G. D., Jan 1 2012, In : Journal of Physiology. 590, 2, p. 395-407 13 p.

Research output: Contribution to journalArticle

30 Scopus citations

Tadalafil alleviates muscle ischemia in patients with becker muscular dystrophy

Martin, E. A., Barresi, R., Byrne, B. J., Tsimerinov, E. I., Scott, B. L., Walker, A. E., Gurudevan, S. V., Anene, F., Elashoff, R. M., Thomas, G. & Victor, R. G., Nov 28 2012, In : Science Translational Medicine. 4, 162, 162ra155.

Research output: Contribution to journalArticle

68 Scopus citations

Treatment with a Nitric Oxide-Donating NSAID Alleviates Functional Muscle Ischemia in the Mouse Model of Duchenne Muscular Dystrophy

Thomas, G. D., Ye, J., de Nardi, C., Monopoli, A., Ongini, E. & Victor, R. G., Nov 5 2012, In : PloS one. 7, 11, e49350.

Research output: Contribution to journalArticle

26 Scopus citations
2011

Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2

Ramesh, S., Morrell, C. N., Tarango, C., Thomas, G. D., Yuhanna, I. S., Girardi, G., Herz, J., Urbanus, R. T., De Groot, P. G., Thorpe, P. E., Salmon, J. E., Shaul, P. W. & Mineo, C., Jan 4 2011, In : Journal of Clinical Investigation. 121, 1, p. 120-131 12 p.

Research output: Contribution to journalArticle

101 Scopus citations

Functional sympatholysis is impaired in hypertensive humans

Vongpatanasin, W., Wang, Z., Arbique, D., Arbique, G., Adams-Huet, B., Mitchell, J. H., Victor, R. G. & Thomas, G. D., Mar 1 2011, In : Journal of Physiology. 589, 5, p. 1209-1220 12 p.

Research output: Contribution to journalArticle

68 Scopus citations

Neural control of the circulation

Thomas, G. D., Mar 2011, In : American Journal of Physiology - Advances in Physiology Education. 35, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

67 Scopus citations
2010

Adenovirus-mediated leptin expression normalises hypertension associated with diet-induced obesity

Zhang, W., Telemaque, S., Augustyniak, R. A., Anderson, P., Thomas, G. D., An, J., Wang, Z., Newgard, C. B. & Victor, R. G., Mar 1 2010, In : Journal of Neuroendocrinology. 22, 3, p. 175-180 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice

Chambliss, K. L., Wu, Q., Oltmann, S., Konaniah, E. S., Umetani, M., Korach, K. S., Thomas, G. D., Mineo, C., Yuhanna, I. S., Kim, S. H., Madak-Erdogan, Z., Maggi, A., Dineen, S. P., Roland, C. L., Hui, D. Y., Brekken, R. A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. & Shaul, P. W., Jul 1 2010, In : Journal of Clinical Investigation. 120, 7, p. 2319-2330 12 p.

Research output: Contribution to journalArticle

172 Scopus citations
2009

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy

Lai, Y., Thomas, G. D., Yue, Y., Yang, H. T., Li, D., Long, C., Judge, L., Bostick, B., Chamberlain, J. S., Terjung, R. L. & Duan, D., Mar 2 2009, In : Journal of Clinical Investigation. 119, 3, p. 624-635 12 p.

Research output: Contribution to journalArticle

236 Scopus citations

Inhibition of nitric oxide synthase evokes central sympatho-excitation in healthy humans

Young, C. N., Fisher, J. P., Gallagher, K. M., Whaley-Connell, A., Chaudhary, K., Victor, R. G., Thomas, G. D. & Fadel, P. J., Oct 1 2009, In : Journal of Physiology. 587, 20, p. 4977-4986 10 p.

Research output: Contribution to journalArticle

40 Scopus citations
2007

C-reactive protein causes downregulation of vascular angiotensin subtype 2 receptors and systolic hypertension in mice

Vongpatanasin, W., Thomas, G. D., Schwartz, R., Cassis, L. A., Osborne-Lawrence, S., Hahner, L., Gibson, L. L., Black, S., Samols, D. & Shaul, P. W., Feb 1 2007, In : Circulation. 115, 8, p. 1020-1028 9 p.

Research output: Contribution to journalArticle

69 Scopus citations
2006

Reactive oxygen species impair sympathetic vasoregulation in skeletal muscle in angiotensin II-dependent hypertension

Zhao, W., Swanson, S. A., Ye, J., Li, X., Shelton, J. M., Zhang, W. & Thomas, G. D., Oct 1 2006, In : Hypertension. 48, 4, p. 637-643 7 p.

Research output: Contribution to journalArticle

60 Scopus citations

Skin blood flow influences near-infrared spectroscopy-derived measurements of tissue oxygenation during heat stress

Davis, S. L., Fadel, P. J., Cui, J., Thomas, G. D. & Crandall, C. G., Jan 1 2006, In : Journal of applied physiology. 100, 1, p. 221-224 4 p.

Research output: Contribution to journalArticle

118 Scopus citations

Smooth muscle-specific dystrophin expression improves aberrant vasoregulation in mdx mice

Ito, K., Kimura, S., Ozasa, S., Matsukura, M., Ikezawa, M., Yoshioka, K., Ueno, H., Suzuki, M., Araki, K., Yamamura, K. I., Miwa, T., Dickson, G., Thomas, G. D. & Miike, T., Jul 15 2006, In : Human Molecular Genetics. 15, 14, p. 2266-2275 10 p.

Research output: Contribution to journalArticle

43 Scopus citations
2005

FcγRIIB mediates C-reactive protein inhibition of endothelial NO synthase

Mineo, C., Gormley, A. K., Yuhanna, I. S., Osborne-Lawrence, S., Gibson, L. L., Hahner, L., Shohet, R. V., Black, S., Salmon, J. E., Samols, D., Karp, D. R., Thomas, G. D. & Shaul, P. W., Nov 1 2005, In : Circulation research. 97, 11, p. 1124-1131 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

α-Adrenoceptor constrictor responses and their modulation in slow-twitch and fast-twitch mouse skeletal muscle

Lambert, D. G. & Thomas, G. D., Mar 15 2005, In : Journal of Physiology. 563, 3, p. 821-829 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2004

Augmented sympathetic vasoconstriction in exercising forearms of postmenopausal women is reversed by oestrogen therapy

Fadel, P. J., Wang, Z., Watanabe, H., Arbique, D., Vongpatanasin, W. & Thomas, G., Dec 15 2004, In : Journal of Physiology. 561, 3, p. 893-901 9 p.

Research output: Contribution to journalArticle

62 Scopus citations

Noninvasive assessment of sympathetic vasoconstriction in human and rodent skeletal muscle using near-infrared spectroscopy and Doppler ultrasound

Fadel, P. J., Keller, D. M., Watanabe, H., Raven, P. B. & Thomas, G. D., Apr 1 2004, In : Journal of applied physiology. 96, 4, p. 1323-1330 8 p.

Research output: Contribution to journalArticle

71 Scopus citations
2003

Impaired vasomodulation is associated with reduced neuronal nitric oxide synthase in skeletal muscle of ovariectomized rats

Fadel, P. J., Zhao, W. & Thomas, G., May 15 2003, In : Journal of Physiology. 549, 1, p. 243-253 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Vasomodulation by skeletal muscle-derived nitric oxide requires α-syntrophin-mediated sarcolemmal localization of neuronal nitric oxide synthase

Thomas, G. D., Shaul, P. W., Yuhanna, I. S., Froehner, S. C. & Adams, M. E., Mar 21 2003, In : Circulation research. 92, 5, p. 554-560 7 p.

Research output: Contribution to journalArticle

105 Scopus citations
2002

Nitric oxide-dependent modulation of sympathetic neural control of oxygenation in exercising human skeletal muscle

Chavoshan, B., Sander, M., Sybert, T. E., Hansen, J., Victor, R. G. & Thomas, G. D., Apr 1 2002, In : Journal of Physiology. 540, 1, p. 377-386 10 p.

Research output: Contribution to journalArticle

94 Scopus citations
2001
69 Scopus citations
2000

Functional muscle ischemia in neuronal nitric oxide synthase-deficient skeletal muscle of children with Duchenne muscular dystrophy

Sander, M., Chavoshan, B., Harris, S. A., Iannaccone, S. T., Stull, J. T., Thomas, G. & Victor, R. G., Dec 5 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 25, p. 13818-13823 6 p.

Research output: Contribution to journalArticle

310 Scopus citations

Metabolic modulation of sympathetic vasoconstriction in exercising skeletal muscle

Hansen, J., Sander, M. & Thomas, G. D., Apr 20 2000, In : Acta Physiologica Scandinavica. 168, 4, p. 489-503 15 p.

Research output: Contribution to journalArticle

55 Scopus citations

Metabolic modulation of sympathetic vasoconstriction in human skeletal muscle: Role of tissue hypoxia

Hansen, J., Sander, M., Hald, C. F., Victor, R. G. & Thomas, G. D., Sep 1 2000, In : Journal of Physiology. 527, 2, p. 387-396 10 p.

Research output: Contribution to journalArticle

63 Scopus citations
1999

Exercise-induced attenuation of alpha-adrenoceptor mediated vastconstriction in humans: Evidence from phase-contrast MRI

Hansen, J., Sayad, D., Thomas, G. D., Clarke, G. D., Peshock, R. M. & Victor, R. G., Jan 1 1999, In : Cardiovascular Research. 41, 1, p. 220-228 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Magnetic resonance imaging and invasive evaluation of development of heart failure in transgenic mice with myocardial expression of tumor necrosis factor-α

Franco, F., Thomas, G. D., Giroir, B., Bryant, D., Bullock, M. C., Chwialkowski, M. C., Victor, R. G. & Peshock, R. M., Jan 26 1999, In : Circulation. 99, 3, p. 448-454 7 p.

Research output: Contribution to journalArticle

121 Scopus citations
1998

Impaired metabolic modulation of α-adrenergic vasoconstriction in dystrophin-deficient skeletal muscle

Thomas, G. D., Sander, M., Lau, K. S., Huang, P. L., Stull, J. T. & Victor, R. G., Dec 8 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 25, p. 15090-15095 6 p.

Research output: Contribution to journalArticle

306 Scopus citations

Invited editorial on "Effect of arterial occlusion on responses of group III and IV afferents to dynamic exercise".

Thomas, G., Chavoshan, B., Sander, M. & Victor, R. G., Jun 1 1998, In : Journal of applied physiology (Bethesda, Md. : 1985). 84, 6, p. 1825-1826 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Nitric oxide mediates contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscle

Thomas, G. D. & Victor, R. G., Feb 1 1998, In : Journal of Physiology. 506, 3, p. 817-826 10 p.

Research output: Contribution to journalArticle

172 Scopus citations
1997

ATP-sensitive potassium channels mediate contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscle

Thomas, G. D., Hansen, J. & Victor, R. G., Jun 1 1997, In : Journal of Clinical Investigation. 99, 11, p. 2602-2609 8 p.

Research output: Contribution to journalArticle

74 Scopus citations

Differential modulation of cortical synaptic activity by calcineurin (phosphatase 2B) versus phosphatases 1 and 2A

Thomas, G. D., O'Rourke, B., Sikkink, R., Rusnak, F., Marban, E. & Victor, R. G., Feb 21 1997, In : Brain research. 749, 1, p. 101-108 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Oxidation of lactate and acetate in rat skeletal muscle: Analysis by 13C-nuclear magnetic resonance spectroscopy

Bertocci, L. A., Jones, J. G., Malloy, C. R., Victor, R. G. & Thomas, G. D., Jul 1997, In : Journal of applied physiology. 83, 1, p. 32-39 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Sympathetic vasoconstriction is attenuated by nitric oxide in contracting rat hindlimb

Thomas, G. & Victor, R. G., 1997, In : FASEB Journal. 11, 3

Research output: Contribution to journalArticle

1996

ARK KATP channels involved in the contraction-induced attenuation oh alpha2 adrenergic vasoconstriction in rat hindlimb?

Thomas, G. D., Hansen, J. & Victor, R., Dec 1 1996, In : FASEB Journal. 10, 3, p. A571

Research output: Contribution to journalArticle

Differential sympathetic neural control of oxygenation in resting and exercising human skeletal muscle

Hansen, J., Thomas, G. D., Harris, S. A., Parsons, W. J. & Victor, R. G., Jul 15 1996, In : Journal of Clinical Investigation. 98, 2, p. 584-596 13 p.

Research output: Contribution to journalArticle

108 Scopus citations

Sympathetic neural mechanisms of cyclosporine-induced hypertension

Sander, M., Lyson, T., Thomas, G. & Victor, R. G., Jan 1 1996, In : American journal of hypertension. 9, 11, p. 121S-138S

Research output: Contribution to journalArticle

70 Scopus citations
1995

Presynaptic modulation of cortical synaptic activity by calcineurin

Victor, R. G., Thomas, G. D., Marban, E. & O'Rourke, B., Jul 3 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 14, p. 6269-6273 5 p.

Research output: Contribution to journalArticle

87 Scopus citations
1994
136 Scopus citations

Muscle metaboreflex triggers parallel sympathetic activation in exercising and resting human skeletal muscle

Hansen, J., Thomas, G. D., Jacobsen, T. N. & Victor, R. G., Jan 1 1994, In : American Journal of Physiology - Heart and Circulatory Physiology. 266, 6 35-6, p. H2508-H2514

Research output: Contribution to journalArticle

96 Scopus citations
1991
4 Scopus citations

Chemical sympathectomy alters the development of hypertension in miniature swine

Thomas, G. D., O'Hagan, K. P. & Zambraski, E. J., Jan 1 1991, In : Hypertension. 17, 3, p. 357-362 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
1990

Effects of 6-hydroxydopamine in hypertensive adult miniature swine

Thomas, G. D., O'hagan, K. P. & Zambraski, E. J., Jan 1 1990, In : Clinical and Experimental Hypertension. A12, 4, p. 647-661 15 p.

Research output: Contribution to journalArticle

2 Scopus citations

Renal denervation decreases blood pressure in doca-treated miniature swine with established hypertension

O‘Hagan, K. P., Thomas, G. D. & Zambraski, E. J., Jan 1990, In : American journal of hypertension. 3, 1, p. 62-64 3 p.

Research output: Contribution to journalArticle

36 Scopus citations