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Research Output 1977 2019

2019

Multiphoton and harmonic generation imaging methods enable direct visualization of drug nanoparticle carriers in conjunction with vasculature in fibrotic prostate tumor mouse model

Abraham, T., Clawson, G., McGovern, C. O., Edris, W., Tang, X., Adair, J. H. & Matters, G., Jan 1 2019, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVII. Tarnok, A., Leary, J. F. & Farkas, D. L. (eds.). SPIE, 108811T. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 10881).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Drug Carriers
Harmonic generation
Nanoparticles
mice
Tumors
2018

Transdifferentiation of Human Circulating Monocytes Into Neuronal-Like Cells in 20 Days and Without Reprograming

Bellon, A., Wegener, A., Lescallette, A. R., Valente, M., Yang, S. K., Gardette, R., Matricon, J., Mouaffak, F., Watts, P., Vimeux, L., Yun, J. K., Kawasawa, Y. I., Clawson, G. A., Blandin, E., Chaumette, B., Jay, T. M., Krebs, M. O., Feuillet, V. & Hosmalin, A., Sep 19 2018, In : Frontiers in Molecular Neuroscience. 11, 323.

Research output: Contribution to journalArticle

Monocytes
Neurons
Neuronal Plasticity
Electrophysiology
Dopamine Receptors
7 Citations (Scopus)

Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

Linton, S. S., Abraham, T., Liao, J., Clawson, G. A., Butler, P. J., Fox, T., Kester, M. & Matters, G. L., Nov 2018, In : PloS one. 13, 11, e0206759.

Research output: Contribution to journalArticle

exosomes
Exosomes
pancreatic neoplasms
Macrophages
Pancreatic Neoplasms
2017
13 Citations (Scopus)

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

Clawson, G. A., Abraham, T., Pan, W., Tang, X., Linton, S. S., McGovern, C. O., Loc, W. S., Smith, J. P., Butler, P. J., Kester, M., Adair, J. H. & Matters, G. L., Feb 2017, In : Nucleic Acid Therapeutics. 27, 1, p. 23-35 13 p.

Research output: Contribution to journalArticle

Nucleotide Aptamers
Cholecystokinin B Receptor
Adenocarcinoma
Confocal microscopy
GTP-Binding Proteins
4 Citations (Scopus)

Biologic Evaluation of Diabetes and Local Recurrence in Non-Small Cell Lung Cancer

Yang, X., Liu, Y., Mani, H., Olson, J., Clawson, G., Caruso, C., Bruggeman, R., Varlotto, J. M., Zander, D. S. & Rassaei, N., Jan 1 2017, In : Pathology and Oncology Research. 23, 1, p. 73-77 5 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Cadherins
Non-Small Cell Lung Carcinoma
Somatomedin Receptors
Recurrence
2 Citations (Scopus)

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

Loc, W. S., Linton, S. S., Wilczynski, Z. R., Matters, G., McGovern, C. O., Abraham, T., Fox, T., Gigliotti, C. M., Tang, X., Tabakovic, A., Martin, J. A., Clawson, G., Smith, J. P., Butler, P. J., Kester, M. & Adair, J. H., Oct 1 2017, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 13, 7, p. 2313-2324 12 p.

Research output: Contribution to journalArticle

Bioactivity
Pancreatic Neoplasms
Encapsulation
Nanoparticles
Calcium
6 Citations (Scopus)

"Stealth dissemination" of macrophage-tumor cell fusions cultured from blood of patients with pancreatic ductal adenocarcinoma

Clawson, G. A., Matters, G. L., Xin, P., McGovern, C., Wafula, E., DePamphilis, C., Meckley, M., Wong, J., Stewart, L., D’Jamoos, C., Altman, N., Kawasawa, Y. I., Du, Z., Honaas, L. & Abraham, T., Sep 2017, In : PloS one. 12, 9, e0184451.

Research output: Contribution to journalArticle

cell fusion
Cell Fusion
Macrophages
adenocarcinoma
Tumors
2016
9 Citations (Scopus)

Histone deacetylase inhibitors as cancer therapeutics

Clawson, G. A., Aug 2016, In : Annals of Translational Medicine. 4, 15, 287.

Research output: Contribution to journalComment/debate

Histone Deacetylase Inhibitors
Histone Deacetylases
Epigenomics
Protein Isoforms
Neoplasms
6 Citations (Scopus)

Perioperative circulating tumor cell detection: Current perspectives

Kaifi, J. T., Li, G., Clawson, G., Kimchi, E. T. & Staveley-O'Carroll, K. F., Aug 2 2016, In : Cancer Biology and Therapy. 17, 8, p. 859-869 11 p.

Research output: Contribution to journalReview article

Circulating Neoplastic Cells
Neoplasms
Metastasectomy
Bone Marrow
Recurrence
2015
27 Citations (Scopus)

Circulating tumor cell isolation during resection of colorectal cancer lung and liver metastases: A prospective trial with different detection techniques

Kaifi, J. T., Kunkel, M., Das, A., Harouaka, R. A., Dicker, D. T., Li, G., Zhu, J., Clawson, G. A., Yang, Z., Reed, M. F., Gusani, N. J., Kimchi, E. T., Staveley-O’Carroll, K. F., Zheng, S. Y. & El-Deiry, W. S., Jan 1 2015, In : Cancer Biology and Therapy. 16, 5, p. 699-708 10 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Cell Separation
Liver Neoplasms
Colorectal Neoplasms
Lung Neoplasms
22 Citations (Scopus)
cell fusion
Cell Fusion
Macrophages
melanoma
Tumors
2013

Biorecognition by DNA oligonucleotides after exposure to photoresists and resist removers

Dean, S. L., Morrow, T. J., Patrick, S., Li, M., Clawson, G. A., Mayer, T. S. & Keating, C. D., Sep 10 2013, In : Langmuir. 29, 36, p. 11535-11545 11 p.

Research output: Contribution to journalArticle

oligonucleotides
Oligonucleotides
Photoresists
photoresists
Nanowires
3 Citations (Scopus)

From devils to jobs: Tracking neuroendocrine tumors

Clawson, G., Feb 1 2013, In : Translational Cancer Research. 2, 1, p. 3-5 3 p.

Research output: Contribution to journalEditorial

Neuroendocrine Tumors
Neoplasms
Lung
Endocrine System
Carcinoid Tumor
27 Citations (Scopus)

Fusion for moving

Clawson, G., Jan 1 2013, In : Science. 342, 6159, p. 699-700 2 p.

Research output: Contribution to journalShort survey

Cell Fusion
Leukocytes
Neoplasm Metastasis
Neoplasms
7 Citations (Scopus)

Vagus nerve regulates breast cancer metastasis to the adrenal gland

Erin, N., Barkan, G. A. & Clawson, G. A., Sep 1 2013, In : Anticancer Research. 33, 9, p. 3675-3682 8 p.

Research output: Contribution to journalArticle

Vagus Nerve
Adrenal Glands
Breast Neoplasms
Neoplasm Metastasis
Vagotomy
2012
45 Citations (Scopus)

Circulating tumor cells in melanoma patients

Clawson, G. A., Kimchi, E., Patrick, S. D., Xin, P., Harouaka, R., Zheng, S., Berg, A., Schell, T., Staveley-O'Carroll, K. F., Neves, R. I., Mosca, P. J. & Thiboutot, D., Jul 19 2012, In : PloS one. 7, 7, e41052.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
melanoma
Tumors
Melanoma
Cells
23 Citations (Scopus)

Down-regulation of HtrA1 activates the Epithelial-Mesenchymal transition and ATM DNA damage response pathways

Wang, N., Eckert, K. A., Zomorrodi, A. R., Xin, P., Pan, W., Shearer, D. A., Weisz, J., Maranus, C. D. & Clawson, G. A., Jun 26 2012, In : PloS one. 7, 6, e39446.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Automatic teller machines
DNA damage
DNA Damage
Down-Regulation
5 Citations (Scopus)
Carcinogenesis
Oxidative Stress
Breast
Epithelium
Epithelial Cells
28 Citations (Scopus)

Nanoresonator chip-based RNA sensor strategy for detection of circulating tumor cells: Response using PCA3 as a prostate cancer marker

Sioss, J. A., Bhiladvala, R. B., Pan, W., Li, M., Patrick, S., Xin, P., Dean, S. L., Keating, C. D., Mayer, T. S. & Clawson, G. A., Aug 1 2012, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 8, 6, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
RNA
Tumors
Prostatic Neoplasms
Cells
2010
5 Citations (Scopus)

MicroRNAs align with accessible sites in target mRNAs

Pan, W., Xin, P. & Clawson, G., Feb 15 2010, In : Journal of cellular biochemistry. 109, 3, p. 509-518 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Messenger RNA
RNA
Ribonuclease H
Assays
13 Citations (Scopus)

Primer-free Aptamer selection using a random DNA library

Pan, W., Xin, P., Patrick, S., Dean, S., Keating, C. & Clawson, G., Jul 2010, In : Journal of Visualized Experiments. 41, e2039.

Research output: Contribution to journalArticle

SELEX Aptamer Technique
Gene Library
Nucleotides
DNA
Ligands
7 Citations (Scopus)

Primer-free aptamer selection using a random DNA library.

Pan, W. & Clawson, G. A., 2010, In : Methods in molecular biology (Clifton, N.J.). 629, p. 369-385 17 p.

Research output: Contribution to journalArticle

SELEX Aptamer Technique
Gene Library
Libraries
Oligonucleotides
Regeneration

Primer-free aptamer selection using a random DNA library.

Pan, W., Xin, P., Patrick, S., Dean, S., Keating, C. & Clawson, G., 2010, In : Journal of Visualized Experiments. 41

Research output: Contribution to journalArticle

SELEX Aptamer Technique
Gene Library
Nucleotides
DNA
Ligands
2009
39 Citations (Scopus)

Altered gene expression in breast cancer liver metastases

Erin, N., Wang, N., Xin, P., Bui, V., Weisz, J., Barkan, G. A., Zhao, W., Shearer, D. & Clawson, G., Apr 1 2009, In : International Journal of Cancer. 124, 7, p. 1503-1516 14 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Breast Neoplasms
Neoplasm Metastasis
Gene Expression
Catenins
4 Citations (Scopus)
Protease Inhibitors
Ketones
Phenylalanine
Uterine Cervical Neoplasms
Alanine
27 Citations (Scopus)

The shorter the better: Reducing fixed primer regions of oligonucleotide libraries for aptamer selection

Pan, W. & Clawson, G. A., Apr 1 2009, In : Molecules. 14, 4, p. 1353-1369 17 p.

Research output: Contribution to journalReview article

SELEX Aptamer Technique
primers
DNA Primers
oligonucleotides
Oligonucleotides
2008
17 Citations (Scopus)

Catalytic DNAzymes: Derivations and functions

Pan, W. & Clawson, G. A., Aug 1 2008, In : Expert Opinion on Biological Therapy. 8, 8, p. 1071-1085 15 p.

Research output: Contribution to journalReview article

Catalytic DNA
Nanotechnology
Catalytic RNA
Antisense Oligonucleotides
Bioelectric potentials
131 Citations (Scopus)

IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway

Smith, T. M., Gilliland, K., Clawson, G. A. & Thiboutot, D., Jan 1 2008, In : Journal of Investigative Dermatology. 128, 5, p. 1286-1293 8 p.

Research output: Contribution to journalArticle

Lipogenesis
1-Phosphatidylinositol 4-Kinase
Response Elements
Sterols
Phosphatidylinositols
24 Citations (Scopus)

Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins

Clawson, G., Bui, V., Xin, P., Wang, N. & Pan, W., Sep 1 2008, In : Journal of Cellular Biochemistry. 105, 1, p. 81-88 8 p.

Research output: Contribution to journalArticle

Tumors
Association reactions
Temperature
Peptide Hydrolases
Neoplasms
33 Citations (Scopus)

Minimal primer and primer-free SELEX protocols for selection of aptamers from random DNA libraries

Pan, W., Xin, P. & Clawson, G. A., Mar 1 2008, In : BioTechniques. 44, 3, p. 351-360 10 p.

Research output: Contribution to journalArticle

SELEX Aptamer Technique
Gene Library
Ligands
Libraries
DNA
40 Citations (Scopus)

Vagotomy enhances experimental metastases of 4THMpc breast cancer cells and alters Substance P level

Erin, N., Akdas Barkan, G., Harms, J. F. & Clawson, G., Nov 29 2008, In : Regulatory Peptides. 151, 1-3, p. 35-42 8 p.

Research output: Contribution to journalArticle

Vagotomy
Substance P
Cells
Breast Neoplasms
Neoplasm Metastasis
2007
43 Citations (Scopus)

Systemic targeting inhibitor of κB kinase inhibits melanoma tumor growth

Yang, J., Pan, W. H., Clawson, G. A. & Richmond, A., Apr 1 2007, In : Cancer Research. 67, 7, p. 3127-3134 8 p.

Research output: Contribution to journalArticle

Melanoma
Phosphotransferases
Growth
Neoplasms
Cyclin-Dependent Kinase 4
4 Citations (Scopus)

The chloromethylketone protease inhibitor AAPFCMK also targets ATP-dependent helicases and SAP-domain proteins

Dhamne, C., Drubin, D. A., Duncan, K., Tevethia, M. J. & Clawson, G., Feb 15 2007, In : Journal of Cellular Biochemistry. 100, 3, p. 716-726 11 p.

Research output: Contribution to journalArticle

Protease Inhibitors
Peptide Hydrolases
Adenosine Triphosphate
Polyomavirus Transforming Antigens
Proteins
2006
47 Citations (Scopus)

Antisense applications for biological control

Pan, W. H. & Clawson, G., May 1 2006, In : Journal of cellular biochemistry. 98, 1, p. 14-35 22 p.

Research output: Contribution to journalReview article

Antisense Oligonucleotides
Catalytic DNA
Catalytic RNA
RNA
Small Interfering RNA
6 Citations (Scopus)

A Protease Inhibitor Specifically Inhibits Growth of HPV-Infected Keratinocytes

Drubin, D. A., McLaughlin-Drubin, M. E., Clawson, G. & Meyers, C., Jun 1 2006, In : Molecular Therapy. 13, 6, p. 1142-1148 7 p.

Research output: Contribution to journalArticle

Protease Inhibitors
Keratinocytes
Chymases
Growth
Uterine Cervical Dysplasia
56 Citations (Scopus)

Capsaicin-induced inactivation of sensory neurons promotes a more aggressive gene expression phenotype in breast cancer cells

Erin, N., Zhao, W., Bylander, J., Chase, G. & Clawson, G., Oct 1 2006, In : Breast Cancer Research and Treatment. 99, 3, p. 351-364 14 p.

Research output: Contribution to journalArticle

Capsaicin
Sensory Receptor Cells
Substance P
Caspase 7
Breast Neoplasms
9 Citations (Scopus)

Identifying accessible sites in RNA: The first step in designing antisense reagents

Pan, W. H. & Clawson, G. A., Oct 1 2006, In : Current Medicinal Chemistry. 13, 25, p. 3083-3103 21 p.

Research output: Contribution to journalReview article

Small Interfering RNA
Libraries
RNA
Site selection
Antisense Oligonucleotides
78 Citations (Scopus)

Insulin-like growth factor-1 induces lipid production in human SEB-1 sebocytes via sterol response element-binding protein-1

Smith, T. M., Cong, Z., Gilliland, K. L., Clawson, G. A. & Thiboutot, D. M., Jun 1 2006, In : Journal of Investigative Dermatology. 126, 6, p. 1226-1232 7 p.

Research output: Contribution to journalArticle

Response Elements
Somatomedins
Sterols
Lipogenesis
Carrier Proteins
2005
7 Citations (Scopus)

Comparison of cryopreservation and standard needle biopsy for gene expression profiling of human breast cancer specimens

Drubin, D., Smith, J. S., Liu, W., Zhao, W., Chase, G. A. & Clawson, G. A., Mar 1 2005, In : Breast Cancer Research and Treatment. 90, 1, p. 93-96 4 p.

Research output: Contribution to journalArticle

Cryopreservation
Needle Biopsy
Gene Expression Profiling
Breast Neoplasms
Large-Core Needle Biopsy
2004
24 Citations (Scopus)

A self-processing ribozyme cassette: Utility against human papillomavirus 11 E6/E7 mRNA and hepatitis B virus

Pan, W. H., Xin, P., Morrey, J. D. & Clawson, G. A., Apr 2004, In : Molecular Therapy. 9, 4, p. 596-606 11 p.

Research output: Contribution to journalArticle

Human papillomavirus 11
Catalytic RNA
Hepatitis B virus
Messenger RNA
Staining and Labeling
60 Citations (Scopus)

Capsaicin-mediated Denervation of Sensory Neurons Promotes Mammary Tumor Metastasis to Lung and Heart

Erin, N., Boyer, P. J., Bonneau, R. H., Clawson, G. A. & Welch, D. R., Mar 1 2004, In : Anticancer Research. 24, 2 B, p. 1003-1009 7 p.

Research output: Contribution to journalArticle

Capsaicin
Denervation
Sensory Receptor Cells
Breast Neoplasms
Neoplasm Metastasis
6 Citations (Scopus)

Identification of efficient cleavage sites in long-target RNAs.

Pan, W. H. & Clawson, G., Jan 1 2004, In : Methods in molecular biology (Clifton, N.J.). 252, p. 125-144 20 p.

Research output: Contribution to journalArticle

Libraries
RNA
Magnesium
Gels
Temperature
14 Citations (Scopus)

Inhibition of papilloma progression by antisense oligonucleotides targeted to HPV11 E6/E7 RNA

Clawson, G. A., Miranda, G. Q., Sivarajah, A., Xin, P., Pan, W., Thiboutot, D. & Christensen, N. D., Sep 1 2004, In : Gene Therapy. 11, 17, p. 1331-1341 11 p.

Research output: Contribution to journalArticle

Antisense Oligonucleotides
Papilloma
RNA
In Situ Hybridization
Catalytic DNA
18 Citations (Scopus)

Parameters affecting substance P measurement in heart, lung, and skin

Erin, N. & Clawson, G., Aug 1 2004, In : BioTechniques. 37, 2, p. 232-239 8 p.

Research output: Contribution to journalArticle

Substance P
Skin
Lung
Tissue
Assays
8 Citations (Scopus)

Spontaneous transformation of an immortalized hepatocyte cell line: Potential role of a nuclear protease

Drubin, D. A. & Clawson, G., Sep 15 2004, In : Cancer Letters. 213, 1, p. 39-48 10 p.

Research output: Contribution to journalArticle

Actin Cytoskeleton
Hepatocytes
Peptide Hydrolases
Chymases
Polyomavirus Transforming Antigens
2003
201 Citations (Scopus)
Sebaceous Glands
Steroidogenic Factor 1
Coenzymes
Epidermis
Skin
22 Citations (Scopus)

Rapid identification of efficient target cleavage sites using a hammerhead ribozyme library in an iterative manner

Pan, W. H., Xin, P., Bui, V. & Clawson, G., Jan 1 2003, In : Molecular Therapy. 7, 1, p. 129-139 11 p.

Research output: Contribution to journalArticle

Catalytic RNA
Libraries
RNA Cleavage
Human papillomavirus 16
Cell Culture Techniques
2002
28 Citations (Scopus)

Involvement of the fungal nuclear migration gene nudC human homolog in cell proliferation and mitotic spindle formation

Zhang, M. Y., Huang, N. N., Clawson, G., Osmani, S. A., Pan, W., Xin, P., Razzaque, M. S. & Miller, B., Jan 1 2002, In : Experimental Cell Research. 273, 1, p. 73-84 12 p.

Research output: Contribution to journalArticle

Catalytic RNA
Spindle Apparatus
Cell Proliferation
Genes
Eukaryotic Cells
2001
31 Citations (Scopus)

A selection system for identifying accessible sites in target RNAs

Pan, W. H., Devlin, H. F., Kelley, C., Isom, H. C. & Clawson, G. A., May 20 2001, In : RNA. 7, 4, p. 610-621 12 p.

Research output: Contribution to journalArticle

Catalytic RNA
Catalytic DNA
RNA
Antisense Oligonucleotides
Oligonucleotides
2000
11 Citations (Scopus)

Design and testing of ribozymes for cancer gene therapy

Norris, J. S., Hoel, B., Voeks, D., Maggouta, F., Dahm, M., Pan, W. & Clawson, G., Jan 1 2000, In : Advances in experimental medicine and biology. 465, p. 293-301 9 p.

Research output: Contribution to journalReview article

Gene therapy
Catalytic RNA
Neoplasm Genes
Genetic Therapy
Testing