• 1243 Citations
  • 22 h-Index
1986 …2024
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Research Output 1986 2019

  • 1243 Citations
  • 22 h-Index
  • 43 Article
  • 5 Review article
  • 1 Chapter
  • 1 Comment/debate
2019
1 Citation (Scopus)

Gastrointestinal dysfunction after spinal cord injury

Holmes, G. & Blanke, E. N., Oct 1 2019, In : Experimental Neurology. 320, 113009.

Research output: Contribution to journalReview article

Spinal Cord Injuries
Gastrointestinal Tract
Neurophysiology
Caregivers
Brain Stem
1 Citation (Scopus)

Investigating neurogenic bowel in experimental spinal cord injury: Where to begin?

White, A. & Holmes, G., Feb 1 2019, In : Neural Regeneration Research. 14, 2, p. 222-226 5 p.

Research output: Contribution to journalReview article

Neurogenic Bowel
Spinal Cord Injuries
Caregivers
Colon
Fecal Incontinence

Purinergic receptor expression and function in rat vagal sensory neurons innervating the stomach

Blanke, E. N., Stella, S., Ruiz-Velasco, V. & Holmes, G., Jul 27 2019, In : Neuroscience letters. 706, p. 182-188 7 p.

Research output: Contribution to journalArticle

Nodose Ganglion
Purinergic Receptors
Sensory Receptor Cells
Stomach
Neurons

Recommendations for evaluation of bladder and bowel function in pre-clinical spinal cord injury research

Holmes, G. M., Hubscher, C. H., Krassioukov, A., Jakeman, L. B. & Kleitman, N., Jan 1 2019, (Accepted/In press) In : Journal of Spinal Cord Medicine.

Research output: Contribution to journalReview article

Spinal Cord Injuries
Colon
Urinary Bladder
Animal Models
Outcome Assessment (Health Care)
2018
5 Citations (Scopus)

Anatomical and Functional Changes to the Colonic Neuromuscular Compartment after Experimental Spinal Cord Injury

White, A. R. & Holmes, G., May 1 2018, In : Journal of Neurotrauma. 35, 9, p. 1079-1090 12 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Colon
Smooth Muscle
Myelitis
Inflammation
1 Citation (Scopus)

Diminished gastric prokinetic response to ghrelin in a rat model of spinal cord injury

Besecker, E. M., White, A. R. & Holmes, G., Apr 1 2018, In : Neurogastroenterology and Motility. 30, 4, e13258.

Research output: Contribution to journalArticle

Ghrelin
Spinal Cord Injuries
Stomach
Thoracic Injuries
Fasting
2017
7 Citations (Scopus)

Mesenteric vascular dysregulation and intestinal inflammation accompanies experimental spinal cord injury

Besecker, E. M., Deiter, G. M., Pironi, N., Cooper, T. K. & Holmes, G. M., Jan 1 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 312, 1, p. R146-R156

Research output: Contribution to journalArticle

Spinal Cord Injuries
Blood Vessels
Inflammation
Superior Mesenteric Artery
Hypotension
1 Citation (Scopus)

Neurogastroenterology in spinal cord dysfunction

Holmes, G., Hudson, T. R. & Filart, R., Jun 6 2017, Neurological Aspects of Spinal Cord Injury. Springer International Publishing, p. 397-437 41 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Spinal Cord Injuries
Spinal Cord
Autonomic Dysreflexia
Comorbidity
Wounds and Injuries
2014
4 Citations (Scopus)
Strain gages
Muscle
Rodentia
Stomach
Smooth Muscle
3 Citations (Scopus)

Gastric vagal motoneuron function is maintained following experimental spinal cord injury

Swartz, E. M. & Holmes, G., Jan 1 2014, In : Neurogastroenterology and Motility. 26, 12, p. 1717-1729 13 p.

Research output: Contribution to journalArticle

Motor Neurons
Spinal Cord Injuries
Stomach
Thyrotropin-Releasing Hormone
Reflex
22 Citations (Scopus)

Ghrelin increases vagally mediated gastric activity by central sites of action

Swartz, E. M., Browning, K., Travagli, R. A. & Holmes, G., Feb 1 2014, In : Neurogastroenterology and Motility. 26, 2, p. 272-282 11 p.

Research output: Contribution to journalArticle

Ghrelin
Stomach
Neurons
Microinjections
Cholinergic Agents
18 Citations (Scopus)

Plasticity in the brainstem vagal circuits controlling gastric motor function triggered by corticotropin releasing factor

Browning, K., Babic, T., Toti, L., Holmes, G., Coleman, F. H. & Travagli, R. A., Oct 15 2014, In : Journal of Physiology. 592, 20, p. 4591-4605 15 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Oxytocin
Brain Stem
Stomach
Microinjections
2013
38 Citations (Scopus)

A critical re-evaluation of the specificity of action of perivagal capsaicin

Browning, K., Babic, T., Holmes, G., Swartz, E. & Travagli, R. A., Mar 1 2013, In : Journal of Physiology. 591, 6, p. 1563-1580 18 p.

Research output: Contribution to journalArticle

Capsaicin
Neuropeptides
Unmyelinated Nerve Fibers
Microinjections
Neurons
25 Citations (Scopus)

Longitudinal assessment of food intake, fecal energy loss, and energy expenditure after roux-en-y gastric bypass surgery in high-fat-fed obese rats

Shin, A. C., Zheng, H., Townsend, R. L., Patterson, L. M., Holmes, G. & Berthoud, H. R., Apr 1 2013, In : Obesity Surgery. 23, 4, p. 531-540 10 p.

Research output: Contribution to journalArticle

Gastric Bypass
Energy Metabolism
Eating
Fats
Food Preferences
25 Citations (Scopus)

Vagal afferent fibres determine the oxytocin-induced modulation of gastric tone

Holmes, G. M., Browning, K. N., Babic, T., Fortna, S. R., Coleman, F. H. & Travagli, R. A., Jun 1 2013, In : Journal of Physiology. 591, 12, p. 3081-3100 20 p.

Research output: Contribution to journalArticle

Oxytocin
Stomach
Solitary Nucleus
Metabotropic Glutamate Receptors
Cholinergic Agents
2012
15 Citations (Scopus)

Upper gastrointestinal dysmotility after spinal cord injury: Is diminished vagal sensory processing one culprit?

Holmes, G., Sep 25 2012, In : Frontiers in Physiology. 3 JUL, Article 277.

Research output: Contribution to journalReview article

Solitary Nucleus
Spinal Cord Injuries
Stomach
Neurons
Vagus Nerve
2011
13 Citations (Scopus)
Cholecystokinin
Spinal Cord Injuries
Stomach
Solitary Nucleus
Microinjections
2010
14 Citations (Scopus)

Gastric emptying of enterally administered liquid meal in conscious rats and during sustained anaesthesia

Qualls-Creekmore, E., Tong, M. & Holmes, G., Feb 1 2010, In : Neurogastroenterology and Motility. 22, 2, p. 181-185 5 p.

Research output: Contribution to journalArticle

Gastric Emptying
Urethane
Meals
Anesthesia
Stomach
21 Citations (Scopus)

Time-course of recovery of gastric emptying and motility in rats with experimental spinal cord injury

Qualls-Creekmore, E., Tong, M. & Holmes, G. M., Jan 1 2010, In : Neurogastroenterology and Motility. 22, 1, p. 62-69+e27-28

Research output: Contribution to journalArticle

Gastric Emptying
Spinal Cord Injuries
Spinal Injuries
Contusions
Breath Tests
2009
25 Citations (Scopus)
Cholecystokinin
Brain Stem
Reflex
Stomach
Bethanechol
16 Citations (Scopus)

Gastric dysreflexia after acute experimental spinal cord injury in rats

Tong, M. & Holmes, G., Feb 1 2009, In : Neurogastroenterology and Motility. 21, 2, p. 197-206 10 p.

Research output: Contribution to journalArticle

Spinal Cord Injuries
Stomach
Reflex
Gastroparesis
Brain Stem
53 Citations (Scopus)

Vagally mediated effects of glucagon-like peptide 1: In vitro and in vivo gastric actions

Holmes, G., Browning, K., Tong, M., Qualls-Creekmore, E. & Travagli, R. A., Oct 1 2009, In : Journal of Physiology. 587, 19, p. 4749-4759 11 p.

Research output: Contribution to journalArticle

Glucagon-Like Peptide 1
Stomach
Neurons
Brain Stem
In Vitro Techniques
2007
24 Citations (Scopus)
Body Composition
Spinal Cord Injuries
Body Weight
Diet
Adipose Tissue
2006
52 Citations (Scopus)

Increased expression of mu opioid receptors in animals susceptible to diet-induced obesity

Barnes, M. J., Holmes, G., Primeaux, S. D., York, D. A. & Bray, G. A., Dec 1 2006, In : Peptides. 27, 12, p. 3292-3298 7 p.

Research output: Contribution to journalArticle

mu Opioid Receptor
Nutrition
Rats
Animals
Obesity
2005
5 Citations (Scopus)

5-Hydroxytryptamine2C receptors on pudendal motoneurons innervating the external anal sphincter

Holmes, G., Sep 28 2005, In : Brain research. 1057, 1-2, p. 65-71 7 p.

Research output: Contribution to journalArticle

Anal Canal
Motor Neurons
Horns
Microscopy
Intramuscular Injections
31 Citations (Scopus)

Serotonergic fiber sprouting to external anal sphincter motoneurons after spinal cord contusion

Holmes, G., Van Meter, M. J., Beattie, M. S. & Bresnahan, J. C., Jan 1 2005, In : Experimental Neurology. 193, 1, p. 29-42 14 p.

Research output: Contribution to journalArticle

Contusions
Anal Canal
Motor Neurons
Spinal Injuries
Spinal Cord Injuries
37 Citations (Scopus)

TNFα modulation of visceral and spinal sensory processing

Hermann, G. E., Holmes, G. & Rogers, R. C., May 11 2005, In : Current Pharmaceutical Design. 11, 11, p. 1391-1409 19 p.

Research output: Contribution to journalReview article

Tumor Necrosis Factor-alpha
Touch
Hypersensitivity
Central Nervous System
Substantia Gelatinosa
2004
39 Citations (Scopus)

Immunocytochemical localization of TNF type 1 and type 2 receptors in the rat spinal cord

Holmes, G., Hebert, S. L., Rogers, R. C. & Hermann, G. E., Oct 29 2004, In : Brain research. 1025, 1-2, p. 210-219 10 p.

Research output: Contribution to journalArticle

Receptors, Tumor Necrosis Factor, Type I
Receptors, Tumor Necrosis Factor, Type II
Spinal Cord
Spinal Nerve Roots
Tumor Necrosis Factor-alpha
18 Citations (Scopus)

TNFα-p55 receptors: Medullary brainstem immunocytochemical localization in normal and vagus nerve-transected rats

Hermann, G. E., Hebert, S. L., Van Meter, M. J., Holmes, G. & Rogers, R. C., Apr 9 2004, In : Brain research. 1004, 1-2, p. 156-166 11 p.

Research output: Contribution to journalArticle

Vagus Nerve
Brain Stem
Solitary Nucleus
Tumor Necrosis Factor-alpha
Neurons
2003
45 Citations (Scopus)

Descending spinal projections from the rostral gigantocellular reticular nuclei complex

Hermann, G. E., Holmes, G., Rogers, R. C., Beattie, M. S. & Bresnahan, J. C., Jan 6 2003, In : Journal of Comparative Neurology. 455, 2, p. 210-221 12 p.

Research output: Contribution to journalArticle

Spinal Cord
Pelvic Floor
Reflex
Motor Neurons
Interneurons
2002
19 Citations (Scopus)

Dissociation of the effects of nucleus raphe obscurus or rostral ventrolateral medulla lesions on eliminatory and sexual reflexes

Holmes, G., Hermann, G. E., Rogers, R. C., Bresnahan, J. C. & Beattie, M. S., Feb 1 2002, In : Physiology and Behavior. 75, 1-2, p. 49-55 7 p.

Research output: Contribution to journalArticle

Anal Canal
Reflex
Penile Erection
Nucleus Raphe Obscurus
Abnormal Reflexes
2001
10 Citations (Scopus)

Inhibition of pudendal reflexes in spinal rats: Reassessing the role of serotonin

Holmes, G., Bresnahan, J. C. & Beattie, M. S., Jan 1 2001, In : Physiology and Behavior. 74, 1-2, p. 57-64 8 p.

Research output: Contribution to journalArticle

Thyrotropin-Releasing Hormone
Reflex
Serotonin
Penile Erection
Population
10 Citations (Scopus)

Intrathecal methiothepin and thyrotropin-releasing hormone effects on penile erection

Holmes, G., Stephens, R. L., Bresnahan, J. C. & Beattie, M. S., Jan 1 2001, In : Physiology and Behavior. 73, 1-2, p. 59-64 6 p.

Research output: Contribution to journalArticle

Methiothepin
Penile Erection
Thyrotropin-Releasing Hormone
Reflex
Serotonin Antagonists
1998
27 Citations (Scopus)

Descending projections from the nucleus raphe obscurus to pudendal motoneurons in the male rat

Hermann, G. E., Bresnahan, J. C., Holmes, G., Rogers, R. C. & Beattie, M. S., Aug 10 1998, In : Journal of Comparative Neurology. 397, 4, p. 458-474 17 p.

Research output: Contribution to journalArticle

Motor Neurons
Reflex
Pelvic Floor
Injections
Reticular Formation
31 Citations (Scopus)

External anal sphincter hyperreflexia following spinal transection in the rat

Holmes, G., Rogers, R. C., Bresnahan, J. C. & Beattie, M. S., Jan 1 1998, In : Journal of Neurotrauma. 15, 6, p. 451-457 7 p.

Research output: Contribution to journalArticle

Abnormal Reflexes
Anal Canal
Reflex
Spinal Cord Injuries
Spinal Cord
1997
13 Citations (Scopus)

Differential effects of intrathecal thyrotropin-releasing hormone (TRH) on perineal reflexes in male rats

Holmes, G., Rogers, R. C., Bresnahan, J. C. & Beattie, M. S., Jan 1 1997, In : Physiology and Behavior. 61, 1, p. 57-63 7 p.

Research output: Contribution to journalArticle

Thyrotropin-Releasing Hormone
Reflex
Anal Canal
Motor Neurons
Mediodorsal Thalamic Nucleus
12 Citations (Scopus)

Nucleus raphe obscurus (nRO) regulation of anorectal motility in rats

Holmes, G., Martau, J. M., Hermann, G. E., Rogers, R. C., Bresnahan, J. C. & Beattie, M. S., Jun 6 1997, In : Brain research. 759, 2, p. 197-204 8 p.

Research output: Contribution to journalArticle

Electric Stimulation
Pelvic Floor
Raphe Nuclei
Nucleus Raphe Obscurus
Motor Neurons
1995
9 Citations (Scopus)

Thyrotropin-releasing hormone (TRH) and CNS regulation of anorectal motility in the rat

Holmes, G., Rogers, R. C., Bresnahan, J. C. & Beattie, M. S., Dec 5 1995, In : Journal of the Autonomic Nervous System. 56, 1-2, p. 8-14 7 p.

Research output: Contribution to journalArticle

Thyrotropin-Releasing Hormone
Atropine
Anal Canal
Intravenous Infusions
Ganglia
1994
Mechanics
Muscles
30 Citations (Scopus)

Physiology and mechanics of rat levator ani muscle: Evidence for a sexual function

Holmes, G. & Sachs, B. D., Jan 1 1994, In : Physiology and Behavior. 55, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

Anal Canal
Mechanics
Muscles
Pressure
Rodentia
1993
18 Citations (Scopus)

Electromyographic activity of rat ischiocavernosus muscles during copulation after treatment with a GABA-transaminase inhibitor

Paredes, R. G., Holmes, G., Sachs, B. D. & Agmo, A., Jan 1 1993, In : Behavioral and Neural Biology. 60, 2, p. 118-122 5 p.

Research output: Contribution to journalArticle

4-Aminobutyrate Transaminase
Copulation
Valproic Acid
Muscles
gamma-Aminobutyric Acid
1992
28 Citations (Scopus)

Erectile function and bulbospongiosus EMG activity in estrogen-maintained castrated rats vary with behavioral context

Holmes, G. M. & Sachs, B. D., Sep 1992, In : Hormones and Behavior. 26, 3, p. 406-419 14 p.

Research output: Contribution to journalArticle

Estrogens
Copulation
Muscles
Castration
Testosterone
1991
123 Citations (Scopus)

Electromyographic analysis of male rat perineal muscles during copulation and reflexive erections

Holmes, G., Chapple, W. D., Leipheimer, R. E. & Sachs, B. D., Jan 1 1991, In : Physiology and Behavior. 49, 6, p. 1235-1246 12 p.

Research output: Contribution to journalArticle

Copulation
Muscles
Penile Erection
Ejaculation
Motor Neurons
26 Citations (Scopus)

The ejaculatory reflex in copulating rats: normal bulbospongiosus activity without apparent urethral stimulation

Holmes, G. & Sachs, B. D., Apr 29 1991, In : Neuroscience letters. 125, 2, p. 195-197 3 p.

Research output: Contribution to journalArticle

Reflex
Guanethidine
Ejaculation
Striated Muscle
Muscle Contraction
1988
35 Citations (Scopus)

An IBM-PC based data collection system for recording rodent sexual behavior and for general event recording

Holmes, G., Holmes, D. G. & Sachs, B. D., Jan 1 1988, In : Physiology and Behavior. 44, 6, p. 825-828 4 p.

Research output: Contribution to journalArticle

Information Systems
Sexual Behavior
Rodentia
Microcomputers
Reflex

Brain localization of cholinergic influence on male sex behavior in rats: Antagonists

Hull, E. M., Pehek, E. A., Bitran, D., Holmes, G., Warner, R. K., Band, L. C., Bazzett, T. & Clemens, L. G., Dec 1 1988, In : Pharmacology Biochemistry and Behavior. 31, 1, p. 175-178 4 p.

Research output: Contribution to journalArticle

Preoptic Area
Scopolamine Hydrobromide
Sexual Behavior
Cholinergic Agents
Rats
34 Citations (Scopus)

Brain localization of cholinergic influence on male sex behavior in rats: Agonists

Hull, E. M., Bitran, D., Pehek, E. A., Holmes, G., Warner, R. K., Band, L. C. & Clemens, L. G., Jan 1 1988, In : Pharmacology, Biochemistry and Behavior. 31, 1, p. 169-174 6 p.

Research output: Contribution to journalArticle

Oxotremorine
Preoptic Area
Carbachol
Sexual Behavior
Cholinergic Agents
57 Citations (Scopus)

Regulation of male rat copulatory behavior by preoptic incertohypothalamic dopamine neurons

Bitran, D., Hull, E. M., Holmes, G. & Lookingland, K. J., Jan 1 1988, In : Brain Research Bulletin. 20, 3, p. 323-331 9 p.

Research output: Contribution to journalArticle

Oxidopamine
Dopaminergic Neurons
Preoptic Area
Apomorphine
Injections
25 Citations (Scopus)

Relation of autogrooming to sexual behavior in male rats

Sachs, B. D., Clark, J. T., Molloy, A. G., Bitran, D. & Holmes, G., Jan 1 1988, In : Physiology and Behavior. 43, 5, p. 637-643 7 p.

Research output: Contribution to journalArticle

Grooming
Sexual Behavior
Reflex
Penis
Penile Erection
1986
177 Citations (Scopus)

Dopaminergic control of male sex behavior in rats: Effects of an intracerebrally-infused agonist

Hull, E. M., Bitran, D., Pehek, E. A., Warner, R. K., Band, L. C. & Holmes, G., Apr 2 1986, In : Brain research. 370, 1, p. 73-81 9 p.

Research output: Contribution to journalArticle

Preoptic Area
Sexual Behavior
Copulation
Dopamine Agents
Ejaculation