Research Output per year
Research Output 2004 2019
2019
4
Citations
(Scopus)
Brain cholesterol metabolism and Parkinson's disease
Huang, X., Sterling, N. W., Du, G., Sun, D., Stetter, C., Kong, L., Zhu, Y., Neighbors, J., Lewis, M. M., Chen, H., Hohl, R. J. & Mailman, R. B., Mar 2019, In : Movement Disorders. 34, 3, p. 386-395 10 p.Research output: Contribution to journal › Article
Parkinson Disease
Cholesterol
Brain
Odds Ratio
Logistic Models
1
Citation
(Scopus)
Development and validation of the automated imaging differentiation in parkinsonism (AID-P): a multicentre machine learning study
Archer, D. B., Bricker, J. T., Chu, W. T., Burciu, R. G., McCracken, J. L., Lai, S., Coombes, S. A., Fang, R., Barmpoutis, A., Corcos, D. M., Kurani, A. S., Mitchell, T., Black, M. L., Herschel, E., Simuni, T., Parrish, T. B., Comella, C., Xie, T., Seppi, K., Bohnen, N. I. & 11 others, , Sep 2019, In : The Lancet Digital Health. 1, 5, p. e222-e231Research output: Contribution to journal › Article
Open Access
Parkinsonian Disorders
Diffusion Magnetic Resonance Imaging
Progressive Supranuclear Palsy
Multiple System Atrophy
Area Under Curve
1
Citation
(Scopus)
Higher Hippocampal Mean Diffusivity Values in Asymptomatic Welders
Lee, E. Y., Flynn, M. R., Du, G., Lewis, M. M., Kong, L., Yanosky, J. D., Mailman, R. B. & Huang, X., Apr 1 2019, In : Toxicological Sciences. 168, 2, p. 486-496 11 p.Research output: Contribution to journal › Article
Manganese
Alzheimer Disease
Hippocampus
Brain
Diffusion tensor imaging
5
Citations
(Scopus)
Magnetic resonance T1w/T2w ratio: A parsimonious marker for Parkinson disease
Du, G., Lewis, M. M., Sica, C., Kong, L. & Huang, X., Jan 2019, In : Annals of Neurology. 85, 1, p. 96-104 9 p.Research output: Contribution to journal › Article
Parkinson Disease
Magnetic Resonance Spectroscopy
Sensitivity and Specificity
Area Under Curve
Magnetic Resonance Imaging
Multimodal MRI evaluation of parkinsonian limbic pathologies
Wang, E. W., Du, G., Lewis, M. M., Lee, E. Y., De Jesus, S., Kanekar, S., Kong, L. & Huang, X., Apr 2019, In : Neurobiology of Aging. 76, p. 194-200 7 p.Research output: Contribution to journal › Article
Hippocampus
Nucleus Accumbens
Amygdala
Magnetic Resonance Imaging
Pathology
2018
14
Citations
(Scopus)
Distinct progression pattern of susceptibility MRI in the substantia nigra of Parkinson's patients
Du, G., Lewis, M., Sica, C., He, L., Connor, J., Kong, L., Mailman, R. & Huang, X., Sep 1 2018, In : Movement Disorders. 33, 9, p. 1423-1431 9 p.Research output: Contribution to journal › Article
Substantia Nigra
Control Groups
Parkinson Disease
Longitudinal Studies
Pars Reticulata
13
Citations
(Scopus)
Susceptibility MRI captures nigral pathology in patients with parkinsonian syndromes
Lewis, M., Du, G., Baccon, J., Snyder, A., Murie, B., Cooper, F., Stetter, C., Kong, L., Sica, C., Mailman, R., Connor, J. & Huang, X., Sep 1 2018, In : Movement Disorders. 33, 9, p. 1432-1439 8 p.Research output: Contribution to journal › Article
Synucleins
Parkinsonian Disorders
Substantia Nigra
Pathology
Iron
2017
6
Citations
(Scopus)
Association of neurobehavioral performance with R2* in the caudate nucleus of asymptomatic welders
Lee, E. Y., Eslinger, P. J., Flynn, M. R., Wagner, D., Du, G., Lewis, M. M., Kong, L., Mailman, R. B. & Huang, X., Jan 1 2017, In : NeuroToxicology. 58, p. 66-74 9 p.Research output: Contribution to journal › Article
Welding
Caudate Nucleus
Manganese
Brain
Neuropsychological Tests
3
Citations
(Scopus)
Circulating cholesterol levels may link to the factors influencing Parkinson's Risk
Zhang, L., Wang, X., Wang, M., Sterling, N. W., Du, G., Lewis, M. M., Yao, T., Mailman, R. B., Li, R. & Huang, X., Sep 27 2017, In : Frontiers in Neurology. 8, SEP, 501.Research output: Contribution to journal › Article
Parkinson Disease
Cholesterol
LDL Cholesterol
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Propensity Score
6
Citations
(Scopus)
Combined diffusion tensor imaging and apparent transverse relaxation rate differentiate Parkinson disease and atypical parkinsonism
Du, G., Lewis, M. M., Kanekar, S., Sterling, N. W., He, L., Kong, L., Li, R. & Huang, X., May 2017, In : American Journal of Neuroradiology. 38, 5, p. 966-972 7 p.Research output: Contribution to journal › Article
Progressive Supranuclear Palsy
Multiple System Atrophy
Diffusion Tensor Imaging
Parkinsonian Disorders
Parkinson Disease
4
Citations
(Scopus)
Cortical gray and subcortical white matter associations in Parkinson's disease
Sterling, N. W., Du, G., Lewis, M. M., Swavely, S., Kong, L., Styner, M. & Huang, X., Jan 1 2017, In : Neurobiology of Aging. 49, p. 100-108 9 p.Research output: Contribution to journal › Article
Parkinson Disease
Anisotropy
Atrophy
White Matter
15
Citations
(Scopus)
Free water improves detection of changes in the substantia nigra in parkinsonism: A multisite study
Ofori, E., Krismer, F., Burciu, R. G., Pasternak, O., McCracken, J. L., Lewis, M. M., Du, G., McFarland, N. R., Okun, M. S., Poewe, W., Mueller, C., Gizewski, E. R., Schocke, M., Kremser, C., Li, H., Huang, X., Seppi, K. & Vaillancourt, D. E., Oct 2017, In : Movement Disorders. 32, 10, p. 1457-1464 8 p.Research output: Contribution to journal › Article
Parkinsonian Disorders
Substantia Nigra
Water
Anisotropy
Diffusion Magnetic Resonance Imaging
2
Citations
(Scopus)
Lateralized basal ganglia vulnerability to pesticide exposure in asymptomatic agricultural workers
Lewis, M., Sterling, N. W., Du, G., Lee, E. Y., Shyu, G., Goldenberg, M., Allen, T., Stetter, C., Kong, L., Snipes, S. A., Jones, B. C., Chen, H., Mailman, R. & Huang, X., Jan 1 2017, In : Toxicological Sciences. 159, 1, p. 170-178 9 p.Research output: Contribution to journal › Article
Diffusion tensor imaging
Basal Ganglia
Pesticides
Corpus Striatum
Globus Pallidus
Predicting the multi-domain progression of Parkinson's disease: A Bayesian multivariate generalized linear mixed-effect model
Wang, M., Li, Z., Lee, E. Y., Lewis, M. M., Zhang, L., Sterling, N. W., Wagner, D., Eslinger, P., Du, G. & Huang, X., Sep 25 2017, In : BMC Medical Research Methodology. 17, 1, 147.Research output: Contribution to journal › Article
Parkinson Disease
National Institute of Neurological Disorders and Stroke
Organized Financing
Statistical Models
ROC Curve
2016
5
Citations
(Scopus)
Folded concave penalized learning in identifying multimodal MRI marker for Parkinson's disease
Liu, H., Du, G., Zhang, L., Lewis, M., Wang, X., Yao, T., Li, R. & Huang, X., Aug 1 2016, In : Journal of Neuroscience Methods. 268, p. 1-6 6 p.Research output: Contribution to journal › Article
Parkinson Disease
Learning
Biomarkers
Passive Cutaneous Anaphylaxis
Logistic Models
8
Citations
(Scopus)
Higher plasma LDL-cholesterol is associated with preserved executive and fine motor functions in Parkinson’s disease
Sterling, N. W., Lichtenstein, M., Lee, E. Y., Lewis, M. M., Evans, A., Eslinger, P. J., Du, G., Gao, X., Chen, H., Kong, L. & Huang, X., Jan 1 2016, In : Aging and Disease. 7, 3, p. 237-245 9 p.Research output: Contribution to journal › Article
Open Access
LDL Cholesterol
Parkinson Disease
Cholesterol
Executive Function
Cognition
10
Citations
(Scopus)
Increased R2* in the caudate nucleus of asymptomatic welders
Lee, E. Y., Flynn, M. R., Du, G., Li, Y., Lewis, M. M., Herring, A. H., Buren, E. V., Buren, S. V., Kong, L., Fry, R. C., Snyder, A. M., Connor, J. R., Yang, Q. X., Mailman, R. B. & Huang, X., Apr 1 2016, In : Toxicological Sciences. 150, 2, p. 369-377 9 p., kfv331.Research output: Contribution to journal › Article
Welding
Caudate Nucleus
Manganese
Basal Ganglia
Blood
6
Citations
(Scopus)
Longitudinal T1 relaxation rate (R1) captures changes in short-term Mn exposure in welders
Lewis, M. M., Flynn, M. R., Lee, E. Y., Van Buren, S., Van Buren, E., Du, G., Fry, R. C., Herring, A. H., Kong, L., Mailman, R. B. & Huang, X., Dec 1 2016, In : NeuroToxicology. 57, p. 39-44 6 p.Research output: Contribution to journal › Article
Welding
Blood
Globus Pallidus
Biomarkers
Brain
7
Citations
(Scopus)
Lower fractional anisotropy in the globus pallidus of asymptomatic welders, a marker for long-term welding exposure
Lee, E. Y., Flynn, M. R., Du, G., Lewis, M., Herring, A. H., Van Buren, E., Van Buren, S., Kong, L., Mailman, R. & Huang, X., Sep 1 2016, In : Toxicological Sciences. 153, 1, p. 165-173 9 p., kfw116.Research output: Contribution to journal › Article
Welding
Globus Pallidus
Anisotropy
Manganese
Basal Ganglia
7
Citations
(Scopus)
Parkinson's disease biomarkers program brain imaging repository
Ofori, E., Du, G., Babcock, D., Huang, X. & Vaillancourt, D. E., Jan 1 2016, In : NeuroImage. 124, p. 1120-1124 5 p.Research output: Contribution to journal › Article
Neuroimaging
Parkinson Disease
Biomarkers
Essential Tremor
Information Dissemination
69
Citations
(Scopus)
Quantitative susceptibility mapping of the midbrain in Parkinson's disease
Du, G., Liu, T., Lewis, M. M., Kong, L., Wang, Y., Connor, J., Mailman, R. B. & Huang, X., Mar 1 2016, In : Movement Disorders. 31, 3, p. 317-324 8 p.Research output: Contribution to journal › Article
Mesencephalon
Parkinson Disease
Iron
Levodopa
Magnetic Resonance Imaging
9
Citations
(Scopus)
Stage-dependent loss of cortical gyrification as Parkinson disease "unfolds"
Sterling, N. W., Wang, M., Zhang, L., Lee, E. Y., Du, G., Lewis, M. M., Styner, M. & Huang, X., Mar 22 2016, In : Neurology. 86, 12, p. 1143-1151 9 p.Research output: Contribution to journal › Article
Parkinson Disease
Dementia
Disease Progression
Linear Models
Pathology
12
Citations
(Scopus)
Structural imaging and Parkinson's disease: Moving toward quantitative markers of disease progression
Sterling, N. W., Lewis, M. M., Du, G. & Huang, X., Jan 1 2016, In : Journal of Parkinson's Disease. 6, 3, p. 557-567 11 p.Research output: Contribution to journal › Review article
Parkinson Disease
Disease Progression
Pathology
Brain Diseases
Interneurons
13
Citations
(Scopus)
Synergy as a new and sensitive marker of basal ganglia dysfunction: A study of asymptomatic welders
Lewis, M. M., Lee, E. Y., Jo, H. J., Du, G., Park, J., Flynn, M. R., Kong, L., Latash, M. L. & Huang, X., Sep 1 2016, In : NeuroToxicology. 56, p. 76-85 10 p.Research output: Contribution to journal › Article
Manganese
Basal Ganglia
Iron
Anisotropy
Neurodegenerative diseases
8
Citations
(Scopus)
The key determinants to quality of life in Parkinson's disease patients: Results from the Parkinson's disease biomarker program (PDBP)
He, L., Lee, E. Y., Sterling, N. W., Kong, L., Lewis, M. M., Du, G., Eslinger, P. J. & Huang, X., Jan 1 2016, In : Journal of Parkinson's Disease. 6, 3, p. 523-532 10 p.Research output: Contribution to journal › Article
Parkinson Disease
Biomarkers
Quality of Life
Linear Models
Regression Analysis
21
Citations
(Scopus)
The pattern of gray matter atrophy in Parkinson’s disease differs in cortical and subcortical regions
Lewis, M. M., Du, G., Lee, E. Y., Nasralah, Z., Sterling, N. W., Zhang, L., Wagner, D., Kong, L., Tröster, A. I., Styner, M., Eslinger, P. J., Mailman, R. B. & Huang, X., Jan 1 2016, In : Journal of Neurology. 263, 1, p. 68-75 8 p.Research output: Contribution to journal › Article
Atrophy
Parkinson Disease
Corpus Striatum
Putamen
Gray Matter
2015
3
Citations
(Scopus)
Cortical thinning and cognitive impairment in Parkinson's disease without dementia
Zhang, L., Wang, M., Sterling, N. W., Lee, E. Y., Eslinger, P. J., Wagner, D., Du, G., Lewis, M. M., Truong, Y., Bowman, F. D. & Huang, X., 2015, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. PP, 99, 2465951.Research output: Contribution to journal › Article
Parkinson's Disease
Dementia
Thinning
Parkinson Disease
Brain
11
Citations
(Scopus)
Dopaminergic modulation of arm swing during gait among Parkinson's disease patients
Sterling, N. W., Cusumano, J. P., Shaham, N., Piazza, S. J., Liu, G., Kong, L., Du, G., Lewis, M. M. & Huang, X., Jan 1 2015, In : Journal of Parkinson's Disease. 5, 1, p. 141-150 10 p.Research output: Contribution to journal › Article
Gait
Parkinson Disease
Arm
Dopamine Agents
Forearm
11
Citations
(Scopus)
Side of motor onset is associated with hemisphere-specific memory decline and lateralized gray matter loss in Parkinson's disease
Lee, E. Y., Sen, S., Eslinger, P. J., Wagner, D., Kong, L., Lewis, M. M., Du, G. & Huang, X., May 1 2015, In : Parkinsonism and Related Disorders. 21, 5, p. 465-470 6 p.Research output: Contribution to journal › Article
Parkinson Disease
Parietal Lobe
Brain
Neurodegenerative Diseases
Magnetic Resonance Spectroscopy
23
Citations
(Scopus)
T1 relaxation rate (R1) indicates nonlinear mn accumulation in brain tissue of welders with low-level exposure
Lee, E. Y., Flynn, M. R., Du, G., Lewis, M. M., Fry, R., Herring, A. H., Van Buren, E., Van Buren, S., Smeester, L., Kong, L., Yang, Q., Mailman, R. B. & Huang, X., Aug 1 2015, In : Toxicological Sciences. 146, 2, p. 281-289 9 p.Research output: Contribution to journal › Article
Manganese
Brain
Tissue
Welding
Globus Pallidus
2014
13
Citations
(Scopus)
Microstructural changes in the substantia nigra of asymptomatic agricultural workers
Du, G., Lewis, M., Sterling, N. W., Kong, L., Chen, H., Mailman, R. & Huang, X., Jan 1 2014, In : Neurotoxicology and Teratology. 41, p. 60-64 5 p.Research output: Contribution to journal › Article
Substantia Nigra
Pesticides
Parkinson Disease
Anisotropy
Magnetic resonance
41
Citations
(Scopus)
Multi-atlas segmentation of subcortical brain structures via the AutoSeg software pipeline
Wang, J., Vachet, C., Rumple, A., Gouttard, S., Ouziel, C., Perrot, E., Du, G., Huang, X., Gerig, G. & Styner, M., Feb 6 2014, In : Frontiers in Neuroinformatics. 8, FEB, 7.Research output: Contribution to journal › Article
Atlases
Brain
Software
Pipelines
Tissue
24
Citations
(Scopus)
Olfactory-related cortical atrophy is associated with olfactory dysfunction in Parkinson's disease
Lee, E. Y., Eslinger, P., Du, G., Kong, L., Lewis, M. & Huang, X., Jan 1 2014, In : Movement Disorders. 29, 9, p. 1205-1208 4 p.Research output: Contribution to journal › Article
Atrophy
Parkinson Disease
Prefrontal Cortex
Brain
Smell
2013
37
Citations
(Scopus)
Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients
Lee, E. Y., Sen, S., Eslinger, P. J., Wagner, D., Shaffer, M. L., Kong, L., Lewis, M. M., Du, G. & Huang, X., Dec 1 2013, In : Parkinsonism and Related Disorders. 19, 12, p. 1088-1093 6 p.Research output: Contribution to journal › Article
Parkinson Disease
Occipital Lobe
Frontal Lobe
Gray Matter
Corpus Striatum
28
Citations
(Scopus)
Higher iron in the red nucleus marks Parkinson's dyskinesia
Lewis, M., Du, G., Kidacki, M., Patel, N., Shaffer, M. L., Mailman, R. & Huang, X., May 1 2013, In : Neurobiology of Aging. 34, 5, p. 1497-1503 7 p.Research output: Contribution to journal › Article
Red Nucleus
Dyskinesias
Parkinson Disease
Iron
Levodopa
39
Citations
(Scopus)
Striatal shape in Parkinson's disease
Sterling, N. W., Du, G., Lewis, M. M., Dimaio, C., Kong, L., Eslinger, P. J., Styner, M. & Huang, X., Nov 1 2013, In : Neurobiology of Aging. 34, 11, p. 2510-2516 7 p.Research output: Contribution to journal › Article
Corpus Striatum
Putamen
Parkinson Disease
Atrophy
Head
2012
68
Citations
(Scopus)
Imaging nigral pathology and clinical progression in Parkinson's disease
Du, G., Lewis, M. M., Sen, S., Wang, J., Shaffer, M. L., Styner, M., Yang, Q. X. & Huang, X., Nov 1 2012, In : Movement Disorders. 27, 13, p. 1636-1643 8 p.Research output: Contribution to journal › Article
Clinical Pathology
Substantia Nigra
Parkinson Disease
Anisotropy
Diffusion Tensor Imaging
10
Citations
(Scopus)
Serum cholesterol and nigrostriatal R2* values in Parkinson's disease
Du, G., Lewis, M. M., Shaffer, M. L., Chen, H., Yang, Q. X., Mailman, R. B. & Huang, X., Apr 17 2012, In : PloS one. 7, 4, e35397.Research output: Contribution to journal › Article
Parkinson disease
Parkinson Disease
Cholesterol
cholesterol
Iron
2011
112
Citations
(Scopus)
Combined R2* and Diffusion Tensor Imaging Changes in the Substantia Nigra in Parkinson's Disease
Du, G., Lewis, M. M., Styner, M., Shaffer, M. L., Sen, S., Yang, Q. X. & Huang, X., Aug 1 2011, In : Movement Disorders. 26, 9, p. 1627-1632 6 p.Research output: Contribution to journal › Article
Diffusion Tensor Imaging
Anisotropy
Substantia Nigra
Parkinson Disease
Magnetic Resonance Imaging
80
Citations
(Scopus)
Differential involvement of striato- and cerebello-thalamo-cortical pathways in tremor- and akinetic/rigid-predominant Parkinson's disease
Lewis, M. M., Du, G., Sen, S., Kawaguchi, A., Truong, Y., Lee, S., Mailman, R. B. & Huang, X., Mar 17 2011, In : Neuroscience. 177, p. 230-239 10 p.Research output: Contribution to journal › Article
Tremor
Parkinson Disease
Corpus Striatum
Hypokinesia
Basal Ganglia Diseases
36
Citations
(Scopus)
Manganese accumulation in the olfactory bulbs and other brain regions of "asymptomatic" welders
Sen, S., Flynn, M. R., Du, G., Tröster, A. I., An, H. & Huang, X., May 2 2011, In : Toxicological Sciences. 121, 1, p. 160-167 8 p.Research output: Contribution to journal › Article
Olfactory Bulb
Manganese
Brain
Magnetic resonance
Hand
2008
2
Citations
(Scopus)
Comprehensive evaluation of an image segmentation technique for measuring tumor volume from CT images
Deng, X., Huang, H., Zhu, L., Du, G., Xu, X., Sun, Y., Xu, C., Jolly, M. P., Chen, J., Xiao, J., Merges, R., Suehling, M., Rinck, D., Song, L., Jin, Z., Jiang, Z., Wu, B., Wang, X., Zhang, S. & Peng, W., Jun 18 2008, Medical Imaging 2008 - Image Perception, Observer Performance, and Technology Assessment. 691705. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 6917).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Cone-Beam Computed Tomography
Tumor Burden
Image segmentation
Tumors
tumors
2007
Reconstruction of the digital Chinese human
Qi, L., Zhou, G., Han, X., Du, G., Cao, H., Chai, H., Zhong, Q., Dong, S. & Luo, S., Dec 1 2007, 2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007. p. 140-146 7 p. 4381709. (2007 IEEE/ICME International Conference on Complex Medical Engineering, CME 2007).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Acupuncture
Neurosurgery
Image registration
Macros
Data acquisition
2005
1
Citation
(Scopus)
Automatic segmentation and visualization of brain MRA images for image-guided neurosurgery
Du, G. W., Cao, H. Z. & Luo, S. Q., Aug 1 2005, In : Chinese Journal of Biomedical Engineering. 24, 4, p. 438-442 5 p.Research output: Contribution to journal › Article
Neurosurgery
Brain
Visualization
2004
3
Citations
(Scopus)
High resolution visualization of VCH-female dataset
Du, G., Chai, H., Cao, H. & Luo, S., Jun 1 2004, In : Proceedings of SPIE - The International Society for Optical Engineering. 5444, p. 453-458 6 p.Research output: Contribution to journal › Conference article
parallel computers
preprocessing
Computer systems
High Resolution
Visualization