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Research Output 1994 2019

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130 Citations (Scopus)

A1, a Bcl-2 family member, prolongs cell survival and permits myeloid differentiation

Lin, E. Y., Orlofsky, A., Wang, H. G., Reed, J. C. & Prystowsky, M. B., Feb 1 1996, In : Blood. 87, 3, p. 983-992 10 p.

Research output: Contribution to journalArticle

Interleukin-3
Cell Survival
Cells
Myeloid Cells
Transfection
95 Citations (Scopus)

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy

Yang, Y., Fiskus, W., Yong, B., Atadja, P., Takahashi, Y., Pandita, T. K., Wang, H. G. & Bhalla, K. N., Apr 23 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 17, p. 6841-6846 6 p.

Research output: Contribution to journalArticle

Sumoylation
Autophagy
Proteins
Class III Phosphatidylinositol 3-Kinases
Histone Deacetylase Inhibitors
22 Citations (Scopus)

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

Tan, S. F., Liu, X., Fox, T. E., Barth, B. M., Sharma, A., Turner, S. D., Awwad, A., Dewey, A., Doi, K., Spitzer, B., Shah, M. V., Morad, S. A. F., Desai, D., Amin, S., Zhu, J., Liao, J. J., Yun, J., Kester, M., Claxton, D., Wang, H-G. & 5 others, Cabot, M. C., Schuchman, E. H., Levine, R. L., Feith, D. J. & Loughran, T. P., Jan 1 2016, In : Oncotarget. 7, 50, p. 83208-83222 15 p.

Research output: Contribution to journalArticle

Acid Ceramidase
Acute Myeloid Leukemia
Ceramides
Sphingolipids
Myeloid Cells
1 Citation (Scopus)

Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation

Tan, S. F., Dunton, W., Liu, X., Fox, T. E., Morad, S. A. F., Desai, D., Doi, K., Conaway, M. R., Amin, S., Claxton, D., Wang, H-G., Kester, M., Cabot, M. C., Feith, D. J. & Loughran, T. P., Jan 1 2019, In : Journal of Lipid Research. 60, 6, p. 1078-1086 9 p.

Research output: Contribution to journalArticle

Acid Ceramidase
P-Glycoprotein
Drug Resistance
Acute Myeloid Leukemia
Up-Regulation
145 Citations (Scopus)

Activation of CPP32 during apoptosis of neurons and astrocytes

Keane, R. W., Srinivasan, A., Foster, L. M., Testa, M. P., Örd, T., Nonner, D., Wang, H-G., Reed, J. C., Bredesen, D. E. & Kayalar, C., Apr 15 1997, In : Journal of Neuroscience Research. 48, 2, p. 168-180 13 p.

Research output: Contribution to journalArticle

Caspase 1
Astrocytes
Peptide Hydrolases
Apoptosis
Neurons
151 Citations (Scopus)

Activity of suberoylanilide hydroxamic acid against human breast cancer cells with amplification of Her-2

Bali, P., Pranpat, M., Swaby, R., Fiskus, W., Yamaguchi, H., Balasis, M., Rocha, K., Wang, H. G., Richon, V. & Bhalla, K., Sep 1 2005, In : Clinical Cancer Research. 11, 17, p. 6382-6389 8 p.

Research output: Contribution to journalArticle

docetaxel
Breast Neoplasms
Apoptosis
vorinostat
Histone Deacetylase Inhibitors
352 Citations (Scopus)

Akt Phosphorylation and Stabilization of X-linked Inhibitor of Apoptosis Protein (XIAP)

Dan, H. C., Sun, M., Kaneko, S., Feldman, R. I., Nicosia, S. V., Wang, H-G., Tsang, B. K. & Cheng, J. Q., Feb 13 2004, In : Journal of Biological Chemistry. 279, 7, p. 5405-5412 8 p.

Research output: Contribution to journalArticle

X-Linked Inhibitor of Apoptosis Protein
Phosphorylation
Stabilization
Cells
Cisplatin
20 Citations (Scopus)

An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure

Takahashi, Y., He, H., Tang, Z., Hattori, T., Liu, Y., Young, M. M., Serfass, J. M., Chen, L., Gebru, M., Chen, C., Wills, C. A., Atkinson, J. M., Chen, H., Abraham, T. & Wang, H-G., Dec 1 2018, In : Nature communications. 9, 1, 2855.

Research output: Contribution to journalArticle

Endosomal Sorting Complexes Required for Transport
regulators
Autophagy
classifying
closures
28 Citations (Scopus)

Androgen receptor-dependent regulation of Bcl-xL expression: Implication in prostate cancer progression

Sun, A., Tang, J., Hong, Y., Song, J., Terranova, P. F., Thrasher, J. B., Svojanovsky, S., Wang, H. G. & Li, B., Mar 1 2008, In : Prostate. 68, 4, p. 453-461 9 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Androgens
Castration
Cell Proliferation
79 Citations (Scopus)

Anoikis, initiated by MCL-1 degradation and Bim induction, is deregulated during oncogenesis

Woods, N. T., Yamaguchi, H., Lee, F. Y., Bhalla, K. N. & Wang, H-G., Nov 15 2007, In : Cancer Research. 67, 22, p. 10744-10752 9 p.

Research output: Contribution to journalArticle

Anoikis
Carcinogenesis
Glycogen Synthase Kinase 3
1-Phosphatidylinositol 4-Kinase
Mitogen-Activated Protein Kinases
29 Citations (Scopus)

Anti-cancer drug discovery and development bcl-2 family small molecule inhibitors

Liu, Q. & Wang, H. G., Nov 1 2012, In : Communicative and Integrative Biology. 5, 6, p. 557-565 9 p.

Research output: Contribution to journalArticle

antineoplastic agents
B-Cell Lymphoma
Drug Discovery
lymphoma
B-lymphocytes
250 Citations (Scopus)

Apoptosis regulation by interaction of Bcl-2 protein and Raf-1 kinase

Wang, H. G., Miyashita, T., Takayama, S., Sato, T., Torigoe, T., Krajewski, S., Tanaka, S., Hovey, L., Troppmair, J., Rapp, U. R. & Reed, J. C., Sep 1 1994, In : Oncogene. 9, 9, p. 2751-2756 6 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-raf
Apoptosis
Sf9 Cells
Proteins
Baculoviridae
35 Citations (Scopus)

A protective role for the human SMG-1 kinase against tumor necrosis factor-α-induced apoptosis

Oliveira, V., Romanow, W. J., Geisen, C., Otterness, D. M., Mercurio, F., Wang, H-G., Dalton, W. S. & Abraham, R. T., May 9 2008, In : Journal of Biological Chemistry. 283, 19, p. 13174-13184 11 p.

Research output: Contribution to journalArticle

Genitalia
Tumor Necrosis Factor-alpha
Morphogenesis
Apoptosis
Cells
51 Citations (Scopus)

A role of the C-terminal region of human Rad9 (hRad9) in nuclear transport of the hRad9 checkpoint complex

Hirai, I. & Wang, H-G., Jul 12 2002, In : Journal of Biological Chemistry. 277, 28, p. 25722-25727 6 p.

Research output: Contribution to journalArticle

Cell Nucleus Active Transport
DNA
Hydroxyurea
Ionizing radiation
Proliferating Cell Nuclear Antigen
56 Citations (Scopus)

Arsenic trioxide (As2O3) induces apoptosis through activation of Bax in hematopoietic cells

Zheng, Y., Yamaguchi, H., Tian, C., Lee, M. W., Tang, H., Wang, H. G. & Chen, Q., May 5 2005, In : Oncogene. 24, 20, p. 3339-3347 9 p.

Research output: Contribution to journalArticle

Apoptosis
Reactive Oxygen Species
Cytosol
Mitochondria
Thioctic Acid
42 Citations (Scopus)

A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α

Chen, S., Hoffman, N. E., Shanmughapriy, S., Bao, L., Keefer, K., Conrad, K., Merali, S., Takahashi, Y., Abraham, T., Hirschler-Laszkiewicz, I., Wang, J. F., Zhang, X. Q., Song, J., Barrero, C., Shi, Y., Imamura, Y., Bayerl, M., Sun, T., Barbour, M., Wang, H-G. & 3 others, Madesh, M., Cheung, J. Y. & Miller, B., Jan 1 2014, In : Journal of Biological Chemistry. 289, 52, p. 36284-36302 19 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Neuroblastoma
Ion Channels
Tumors
Growth
18 Citations (Scopus)

Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis

Tang, Z., Takahashi, Y., Chen, C., Liu, Y., He, H., Tsotakos, N., Serfass, J. M., Gebru, M. T., Chen, H., Young, M. M. & Wang, H. G., Dec 1 2017, In : Cell Death and Differentiation. 24, 12, p. 2127-2138 12 p.

Research output: Contribution to journalArticle

Death Domain Receptor Signaling Adaptor Proteins
Caspase 8
Autophagy
Apoptosis
Membranes
17 Citations (Scopus)

Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model

Liu, Q., Chen, L., Atkinson, J. M., Claxton, D. & Wang, H-G., Jan 1 2016, In : Cell Death and Disease. 7, 9, e2361.

Research output: Contribution to journalArticle

Autophagy
Acute Myeloid Leukemia
Myeloid Cells
Oncogene Fusion
Stem Cells
182 Citations (Scopus)

Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis

Young, M. M., Takahashi, Y., Khan, O., Park, S., Hori, T., Yun, J., Sharma, A. K., Amin, S., Hu, C. D., Zhang, J., Kester, M. & Wang, H. G., Apr 6 2012, In : Journal of Biological Chemistry. 287, 15, p. 12455-12468 14 p.

Research output: Contribution to journalArticle

Death Domain Receptor Signaling Adaptor Proteins
Caspase 8
Chemical activation
Apoptosis
Membranes
34 Citations (Scopus)

BARgaining membranes for autophagosome formation: Regulation of autophagy and tumorigenesis by Bif-1/Endophilin B1

Takahashi, Y., Meyerkord, C. L. & Wang, H-G., Jan 1 2008, In : Autophagy. 4, 1, p. 121-124 4 p.

Research output: Contribution to journalArticle

Autophagy
Carcinogenesis
Membranes
Class III Phosphatidylinositol 3-Kinases
Caspases
21 Citations (Scopus)

Bax-interacting factor-1 expression in prostate cancer

Coppola, D., Oliveri, C., Sayegh, Z., Boulware, D., Takahashi, Y., Pow-Sang, J., Djeu, J. Y. & Wang, H-G., Jan 1 2008, In : Clinical Genitourinary Cancer. 6, 2, p. 117-121 5 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Prostatic Intraepithelial Neoplasia
Prostatic Hyperplasia
Prostate
Staining and Labeling
23 Citations (Scopus)

Bax interacting factor-1 promotes survival and mitochondrial elongation in neurons

Wang, D. B., Uo, T., Kinoshita, C., Sopher, B. L., Lee, R. J., Murphy, S. P., Kinoshita, Y., Garden, G. A., Wang, H-G. & Morrison, R. S., Feb 14 2014, In : Journal of Neuroscience. 34, 7, p. 2674-2683 10 p.

Research output: Contribution to journalArticle

Neurons
Mitochondria
Stroke
Mitochondrial Dynamics
Apoptosis
121 Citations (Scopus)
HCT116 Cells
Thapsigargin
Colonic Neoplasms
Mitochondria
Apoptosis
49 Citations (Scopus)

B cell apoptosis triggered by antigen receptor ligation proceeds via a novel caspase-dependent pathway

Chen, W., Wang, H-G., Srinivasula, S. M., Alnemri, E. S. & Cooper, N. R., Sep 1 1999, In : Journal of Immunology. 163, 5, p. 2483-2491 9 p.

Research output: Contribution to journalArticle

Antigen Receptors
Caspases
Caspase 2
Ligation
B-Lymphocytes
43 Citations (Scopus)

Bcl-2, Raf-1 and mitochondrial regulation of apoptosis

Wang, H-G. & Reed, J. C., Jan 1 1998, In : BioFactors. 8, 1-2, p. 13-16 4 p.

Research output: Contribution to journalArticle

Apoptosis
Mitochondria
Catalytic Domain
Mitochondrial Membranes
Proteins
420 Citations (Scopus)

BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapy

Reed, J. C., Miyashita, T., Takayama, S., Wang, H-G., Sato, T., Krajewski, S., Aimésempé, C., Bodrug, S., Kitada, S. & Hanada, M., Feb 16 1996, In : Journal of cellular biochemistry. 60, 1, p. 23-32 10 p.

Research output: Contribution to journalArticle

Cell death
Cell Death
Neoplasms
Proteins
Apoptosis
318 Citations (Scopus)

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

Wang, H-G., Takayama, S., Rapp, U. R. & Reed, J. C., Jul 9 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 14, p. 7063-7068 6 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-raf
Apoptosis
14-3-3 Proteins
Two-Hybrid System Techniques
Apoptosis Regulatory Proteins
671 Citations (Scopus)

Bcl-2 targets the protein kinase Raf-1 to mitochondria

Wang, H-G., Rapp, U. R. & Reed, J. C., Jan 15 1996, In : Cell. 87, 4, p. 629-638 10 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins c-raf
Mitochondria
Protein Kinases
Apoptosis
Phosphorylation
80 Citations (Scopus)

Bcl-XL protects BimEL-induced Bax conformational change and cytochrome c release independent of interacting with Bax or BimEL

Yamaguchi, H. & Wang, H-G., Nov 1 2002, In : Journal of Biological Chemistry. 277, 44, p. 41604-41612 9 p.

Research output: Contribution to journalArticle

Cytochromes c
Mitochondria
Mitochondrial Membranes
Apoptosis
bcl-2-Associated X Protein
48 Citations (Scopus)

Bcl-XL-templated assembly of its own protein-protein interaction modulator from fragments decorated with thio acids and sulfonyl azides

Hu, X., Sun, J., Wang, H-G. & Manetsch, R., Oct 22 2008, In : Journal of the American Chemical Society. 130, 42, p. 13820-13821 2 p.

Research output: Contribution to journalArticle

Azides
Modulators
Proteins
Acids
bcl-X Protein
11 Citations (Scopus)

Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance

Liu, Y., Takahashi, Y., Desai, N., Zhang, J., Serfass, J. M., Shi, Y. G., Lynch, C. J. & Wang, H-G., Feb 9 2016, In : Scientific reports. 6, 20453.

Research output: Contribution to journalArticle

Insulin Resistance
Adipose Tissue
Homeostasis
Obesity
Lipids
44 Citations (Scopus)

Bif-1 haploinsufficiency promotes chromosomal instability and accelerates Myc-driven lymphomagenesis via suppression of mitophagy

Takahashi, Y., Hori, T., Cooper, T., Liao, J. J., Desai, N., Serfass, J. M., Young, M. M., Park, S., Izu, Y. & Wang, H-G., Feb 28 2013, In : Blood. 121, 9, p. 1622-1632 11 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Haploinsufficiency
Chromosomal Instability
Loss of Heterozygosity
Apoptosis
594 Citations (Scopus)

Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

Takahashi, Y., Coppola, D., Matsushita, N., Cualing, H. D., Sun, M., Sato, Y., Liang, C., Jung, J. U., Cheng, J. Q., Mulé, J. J., Pledger, W. J. & Wang, H-G., Oct 1 2007, In : Nature Cell Biology. 9, 10, p. 1142-1151 10 p.

Research output: Contribution to journalArticle

Autophagy
Carcinogenesis
src Homology Domains
Genes
Microtubule-Associated Proteins

Bif-1 interacts with prohibitin-2 to regulate mitochondrial inner membrane during cell stress and apoptosis

Cho, S. G., Xiao, X., Wang, S., Gao, H., Rafikov, R., Black, S., Huang, S., Ding, H. F., Yoon, Y., Kirken, R. A., Yin, X. M., Wang, H. G. & Dong, Z., Jul 2019, In : Journal of the American Society of Nephrology. 30, 7, p. 1174-1191 18 p.

Research output: Contribution to journalArticle

Mitochondrial Membranes
Apoptosis
Proteolysis
Mitochondrial Dynamics
Kidney
3 Citations (Scopus)

Bif-1 promotes tumor cell migration and metastasis via Cdc42 expression and activity

Zhang, C., Liu, F., Chen, H., Li, N., Luo, Z., Guo, W., Huang, D., Tang, S., Wang, H-G., Cheng, S., Li, Z. & Wang, H., Jan 1 2017, In : Clinical and Experimental Metastasis. 34, 1, p. 11-23 13 p.

Research output: Contribution to journalArticle

Cell Movement
Hepatocellular Carcinoma
Neoplasm Metastasis
Neoplasms
Rho Factor
90 Citations (Scopus)

Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy

Takahashi, Y., Meyerkord, C. L., Hori, T., Runkle, K., Fox, T. E., Kester, M., Loughran, T. P. & Wang, H. G., Jan 2011, In : Autophagy. 7, 1, p. 61-73 13 p.

Research output: Contribution to journalArticle

Autophagy
Starvation
Membranes
Class III Phosphatidylinositol 3-Kinases
Cytoplasmic Structures
22 Citations (Scopus)

Bif-1 suppresses breast cancer cell migration by promoting EGFR Endocytic degradation

Runkle, K. B., Meyerkord, C. L., Desai, N. V., Takahashi, Y. & Wang, H. G., Aug 1 2012, In : Cancer Biology and Therapy. 13, 10, p. 956-966 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor
Cell Movement
Breast Neoplasms
Endosomes
Lysosomes
23 Citations (Scopus)

C6-ceramide nanoliposomes target the warburg effect in chronic lymphocytic leukemia

Ryland, L. K., Doshi, U. A., Shanmugavelandy, S. S., Fox, T. E., Aliaga, C., Broeg, K., Baab, K. T., Young, M. M., Khan, O., Haakenson, J. K., Jarbadan, N. R., Liao, J. J., Wang, H-G., Feith, D. J., Loughran, T. P., Liu, X. & Kester, M., Dec 19 2013, In : PloS one. 8, 12, e84648.

Research output: Contribution to journalArticle

lymphocytic leukemia
ceramides
Ceramides
B-Cell Chronic Lymphocytic Leukemia
long term effects
899 Citations (Scopus)

Ca2+-Induced Apoptosis Through Calcineurin Dephosphorylation of BAD

Wang, H-G., Pathan, N., Ethell, I. M., Krajewski, S., Yamaguchi, Y., Shibasaki, F., McKeon, F., Bobo, T., Franke, T. F. & Reed, J. C., Apr 9 1999, In : Science. 284, 5412, p. 339-343 5 p.

Research output: Contribution to journalArticle

Calcineurin
Apoptosis
Phosphoprotein Phosphatases
Phosphoric Monoester Hydrolases
Cytosol
82 Citations (Scopus)

c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage

Yoshida, K., Komatsu, K., Wang, H-G. & Kufe, D., May 9 2002, In : Molecular and cellular biology. 22, 10, p. 3292-3300 9 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
DNA Damage
Apoptosis
Cell Cycle Proteins
src Homology Domains
37 Citations (Scopus)

Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagy

Hsu, P., Liu, X., Zhang, J., Wang, H-G., Ye, J. M. & Shi, Y., Jan 1 2015, In : Autophagy. 11, 4, p. 643-652 10 p.

Research output: Contribution to journalArticle

Barth Syndrome
Mitochondrial Degradation
Cardiolipins
Oxidative Phosphorylation
Phospholipids
29 Citations (Scopus)

Caspase-3-mediated cleavage of Rad9 during apoptosis

Lee, M. W., Hirai, I. & Wang, H-G., Sep 25 2003, In : Oncogene. 22, 41, p. 6340-6346 7 p.

Research output: Contribution to journalArticle

Caspase 3
DNA Damage
Apoptosis
Cytosol
Caspases
239 Citations (Scopus)

Cell-free reconstitution of Fas-, UV radiation- and ceramide-induced apoptosis

Martin, S. J., Newmeyer, D. D., Mathias, S., Farschon, D. M., Wang, H-G., Reed, J. C., Kolesnick, R. N. & Green, D. R., Jan 1 1995, In : EMBO Journal. 14, 21, p. 5191-5200 10 p.

Research output: Contribution to journalArticle

Ceramides
Ultraviolet radiation
Cell Extracts
Radiation
Apoptosis
496 Citations (Scopus)

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

Yamaguchi, H. & Wang, H-G., Oct 29 2004, In : Journal of Biological Chemistry. 279, 44, p. 45495-45502 8 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Thapsigargin
Cells
Apoptosis
Carcinoma
20 Citations (Scopus)

Depletion of the human ion channel TRPM2 in neuroblastoma demonstrates its key role in cell survival through modulation of mitochondrial reactive oxygen species and bioenergetics

Bao, L., Chen, S. J., Conrad, K., Keefer, K., Abraham, T., Lee, J. P., Wang, J. F., Zhang, X. Q., Hirschler-Laszkiewicz, I., Wang, H. G., Dovat, S., Gans, B., Madesh, M., Cheung, J. Y. & Miller, B. A., Nov 18 2016, In : Journal of Biological Chemistry. 291, 47, p. 24449-24464 16 p.

Research output: Contribution to journalArticle

Neuroblastoma
Ion Channels
Energy Metabolism
Reactive Oxygen Species
Cell Survival
101 Citations (Scopus)

Discovery of marinopyrrole A (maritoclax) as a selective Mcl-1 antagonist that overcomes ABT-737 resistance by binding to and targeting Mcl-1 for proteasomal degradation

Doi, K., Li, R., Sung, S., Wu, H., Liu, Y., Manieri, W., Gowda, K., Awwad, A., Dewey, A., Liu, X., Amin, S., Cheng, C., Qin, Y., Schonbrunn, E., Daughdrill, G., Loughran, T. P., Sebti, S. & Wang, H-G., Mar 23 2012, In : Journal of Biological Chemistry. 287, 13, p. 10224-10235 12 p.

Research output: Contribution to journalArticle

Degradation
Videocassette recorders
Oncology
Hematologic Neoplasms
Proteasome Endopeptidase Complex
53 Citations (Scopus)

Down-regulation of bax-interacting factor-1 in colorectal adenocarcinoma

Coppola, D., Khalil, F., Eschrich, S. A., Boulware, D., Yeatman, T. & Wang, H-G., Nov 15 2008, In : Cancer. 113, 10, p. 2665-2670 6 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Down-Regulation
Microarray Analysis
Staining and Labeling
Neoplasms
14 Citations (Scopus)

Down-regulation of bax-interacting factor 1 in human pancreatic ductal adenocarcinoma

Coppola, D., Helm, J., Ghayouri, M., Malafa, M. P. & Wang, H-G., Apr 1 2011, In : Pancreas. 40, 3, p. 433-437 5 p.

Research output: Contribution to journalArticle

Adenocarcinoma
Down-Regulation
Survival
Carcinogenesis
Autophagy
16 Citations (Scopus)

Dysfunction of nucleus accumbens-1 activates cellular senescence and inhibits tumor cell proliferation and oncogenesis

Zhang, Y., Cheng, Y., Ren, X., Hori, T., Huber-Keener, K. J., Zhang, L., Yap, K. L., Liu, D., Shantz, L., Qin, Z. H., Zhang, S., Wang, J., Wang, H. G., Shih, I. M. & Yang, J. M., Aug 15 2012, In : Cancer Research. 72, 16, p. 4262-4275 14 p.

Research output: Contribution to journalArticle

Cell Aging
Nucleus Accumbens
Carcinogenesis
Cell Proliferation
Neoplasms
168 Citations (Scopus)

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

Quo, F., Nimmanapalli, R., Paranawithana, S., Wittman, S., Griffin, D., Bali, P., O'Bryan, E., Fumero, C., Wang, H-G. & Bhalla, K., May 1 2002, In : Blood. 99, 9, p. 3419-3426 8 p.

Research output: Contribution to journalArticle

Mitochondria
Caspases
Apoptosis
Derivatives
Peptides