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Personal profile

Research interests

Dr. Hong Zheng's research focus is transplant immunology and developmental therapeutics for leukemia. Her study is dedicated to improve the understanding of the complex immune response involved in leukemia pathogenesis and allogeneic hematopoietic stem cell transplantation, and subsequently develop effective leukemia therapeutics.

Currently, she is involved in developing early-phase clinical studies testing the safety and efficacy of immunotherapy for leukemia. Her laboratory studies involve targeting T-cell inhibitory mechanisms as a strategy to improve anti-leukemia immunity.

Clinical interests

Dr. Hong Zheng cares for patients with hematological malignancies, including leukemia and lymphoma, as well as patients undergoing hematopoietic stem cell transplantation.

Professional information

Board-certified in Hematology and Medical Oncology

Education/Academic qualification

Hematology and Oncology, Fellowship, Yale University

… → 2013

Internal Medicine, Residency, Penn State Health Milton S. Hershey Medical Center

… → 2010

Postdoctoral Fellowship, Yale University

… → 2007

Immunology, PhD, University of Connecticut

… → 2003

Clinical Medicine, MD, Capital Medical University

… → 1995

Fingerprint Dive into the research topics where Hong Zheng is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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T-Lymphocytes Medicine & Life Sciences
Acute Myeloid Leukemia Medicine & Life Sciences
Leukemia Medicine & Life Sciences
Heat-Shock Proteins Medicine & Life Sciences
Graft vs Host Disease Medicine & Life Sciences
Cross-Priming Medicine & Life Sciences
Dendritic Cells Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences

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Research Output 2001 2019

  • 848 Citations
  • 13 h-Index
  • 23 Article
  • 3 Review article
  • 1 Letter

Advanced NSCLC patients with high IL-6 levels have altered peripheral T cell population and signaling

Rice, S. J., Liu, X., Zhang, J., Jia, B., Zheng, H. & Belani, C., May 1 2019, In : Lung Cancer. 131, p. 58-61 4 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Interleukin-6
T-Lymphocytes
Population
STAT1 Transcription Factor
1 Citation (Scopus)

Downregulation of CD73 associates with T cell exhaustion in AML patients

Kong, Y., Jia, B., Zhao, C., Claxton, D., Sharma, A., Annageldiyev, C., Fotos, J., Zeng, H., Paulson, R., Prabhu, K. S. & Zheng, H., Apr 24 2019, In : Journal of Hematology and Oncology. 12, 1, 40.

Research output: Contribution to journalArticle

Open Access
Acute Myeloid Leukemia
Down-Regulation
T-Lymphocytes
Adenosine
Neoplasms
1 Citation (Scopus)
Open Access
Acute Myeloid Leukemia
T-Lymphocytes
Leukemia
Transcription Factors
Induction Chemotherapy

Two types of poor immunological responder showing distinct responses to long-term HAART

Kong, Y., Tian, Y., Hao, Y., Chong, X., Xiao, J., Yang, D., Song, C., Han, J., Dai, G., Zhang, F., Zheng, H., Zhao, H. & Zeng, H., Sep 1 2019, In : International Journal of Infectious Diseases. 86, p. 178-187 10 p.

Research output: Contribution to journalArticle

Open Access
Highly Active Antiretroviral Therapy
T-Lymphocytes
Neopterin
T-Lymphocyte Subsets
Regulatory T-Lymphocytes
3 Citations (Scopus)
Leukemia
Bone Marrow
T-Lymphocytes