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Personal profile

Research interests

Dr. Hong Zheng's research focus is transplant immunology and developmental therapeutics for leukemia. Her study is dedicated to improve the understanding of the complex immune response involved in leukemia pathogenesis and allogeneic hematopoietic stem cell transplantation, and subsequently develop effective leukemia therapeutics.

Currently, she is involved in developing early-phase clinical studies testing the safety and efficacy of immunotherapy for leukemia. Her laboratory studies involve targeting T-cell inhibitory mechanisms as a strategy to improve anti-leukemia immunity.

Clinical interests

Dr. Hong Zheng cares for patients with hematological malignancies, including leukemia and lymphoma, as well as patients undergoing hematopoietic stem cell transplantation.

Professional information

Board-certified in Hematology and Medical Oncology

Education/Academic qualification

Hematology and Oncology, Fellowship, Yale University

… → 2013

Internal Medicine, Residency, Penn State Health Milton S. Hershey Medical Center

… → 2010

Postdoctoral Fellowship, Yale University

… → 2007

Immunology, PhD, University of Connecticut

… → 2003

Clinical Medicine, MD, Capital Medical University

… → 1995

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Research Output

  • 987 Citations
  • 15 h-Index
  • 26 Article
  • 3 Review article
  • 1 Letter

CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses

Wang, D., Du, J., Song, Y., Wang, B., Song, R., Hao, Y., Zeng, Y., Xiao, J., Zheng, H., Zeng, H., Zhao, H. & Kong, Y., Jun 30 2020, In : Aging. 12, 12, p. 12032-12050 19 p.

Research output: Contribution to journalArticle

  • Open Access
  • The PI3K/AKT Pathway Inhibitor ISC-4 Induces Apoptosis and Inhibits Growth of Leukemia in Preclinical Models of Acute Myeloid Leukemia

    Annageldiyev, C., Tan, S. F., Thakur, S., Dhanyamraju, P. K., Ramisetti, S. R., Bhadauria, P., Schick, J., Zeng, Z., Sharma, V., Dunton, W., Dovat, S., Desai, D., Zheng, H., Feith, D. J., Loughran, T. P., Amin, S., Sharma, A. K., Claxton, D. & Sharma, A., Apr 1 2020, In : Frontiers in Oncology. 10, 393.

    Research output: Contribution to journalArticle

    Open Access
  • Advanced NSCLC patients with high IL-6 levels have altered peripheral T cell population and signaling

    Rice, S. J., Liu, X., Zhang, J., Jia, B., Zheng, H. & Belani, C. P., May 2019, In : Lung Cancer. 131, p. 58-61 4 p.

    Research output: Contribution to journalArticle

  • Downregulation of CD73 associates with T cell exhaustion in AML patients

    Kong, Y., Jia, B., Zhao, C., Claxton, D. F., Sharma, A., Annageldiyev, C., Fotos, J. S., Zeng, H., Paulson, R. F., Prabhu, K. S. & Zheng, H., Apr 24 2019, In : Journal of Hematology and Oncology. 12, 1, 40.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations