If you made any changes in Pure, your changes will be visible here soon.

Research Output 2001 2019

  • 851 Citations
  • 13 h-Index
  • 24 Article
  • 3 Review article
  • 1 Letter
2019

Advanced NSCLC patients with high IL-6 levels have altered peripheral T cell population and signaling

Rice, S. J., Liu, X., Zhang, J., Jia, B., Zheng, H. & Belani, C., May 1 2019, In : Lung Cancer. 131, p. 58-61 4 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Interleukin-6
T-Lymphocytes
Population
STAT1 Transcription Factor
1 Citation (Scopus)

Downregulation of CD73 associates with T cell exhaustion in AML patients

Kong, Y., Jia, B., Zhao, C., Claxton, D., Sharma, A., Annageldiyev, C., Fotos, J., Zeng, H., Paulson, R., Prabhu, K. S. & Zheng, H., Apr 24 2019, In : Journal of Hematology and Oncology. 12, 1, 40.

Research output: Contribution to journalArticle

Open Access
Acute Myeloid Leukemia
Down-Regulation
T-Lymphocytes
Adenosine
Neoplasms
1 Citation (Scopus)
Open Access
Acute Myeloid Leukemia
T-Lymphocytes
Leukemia
Transcription Factors
Induction Chemotherapy
Open Access
decitabine
Acute Myeloid Leukemia
Therapeutics
T-Lymphocytes
DNA Methylation

Two types of poor immunological responder showing distinct responses to long-term HAART

Kong, Y., Tian, Y., Hao, Y., Chong, X., Xiao, J., Yang, D., Song, C., Han, J., Dai, G., Zhang, F., Zheng, H., Zhao, H. & Zeng, H., Sep 1 2019, In : International Journal of Infectious Diseases. 86, p. 178-187 10 p.

Research output: Contribution to journalArticle

Open Access
Highly Active Antiretroviral Therapy
T-Lymphocytes
Neopterin
T-Lymphocyte Subsets
Regulatory T-Lymphocytes
2018
3 Citations (Scopus)
Leukemia
Bone Marrow
T-Lymphocytes
17 Citations (Scopus)

High Level of Neutrophil Extracellular Traps Correlates with Poor Prognosis of Severe Influenza A Infection

Zhu, L., Liu, L., Zhang, Y., Pu, L., Liu, J., Li, X., Chen, Z., Hao, Y., Wang, B., Han, J., Li, G., Liang, S., Xiong, H., Zheng, H., Li, A., Xu, J. & Zeng, H., Jan 17 2018, In : Journal of Infectious Diseases. 217, 3, p. 428-437 10 p.

Research output: Contribution to journalArticle

Human Influenza
Infection
Multiple Organ Failure
Influenza A virus
Peroxidase
5 Citations (Scopus)

T-cell Immunoglobulin and ITIM Domain Contributes to CD8 + T-cell Immunosenescence

Song, Y., Wang, B., Song, R., Hao, Y., Wang, D., Li, Y., Jiang, Y., Xu, L., Ma, Y., Zheng, H., Kong, Y. & Zeng, H., Apr 1 2018, In : Aging cell. 17, 2, e12716.

Research output: Contribution to journalArticle

Tyrosine
Immunoglobulins
T-Lymphocytes
Programmed Cell Death 1 Receptor
Down-Regulation
2 Citations (Scopus)

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

Wang, L., Jia, B., Claxton, D., Ehmann, W. C., Rybka, W., Mineishi, S., Naik, S., Khawaja, M. R., Sivik, J., Han, J., Hohl, R. & Zheng, H., Sep 2 2018, In : OncoImmunology. 7, 9, e1469594.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
T-Lymphocytes
Leukemia
Myeloid-Derived Suppressor Cells
Immunoglobulin Domains
2017
10 Citations (Scopus)

A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220

Hou, P., Wu, C., Wang, Y., Qi, R., Bhavanasi, D., Zuo, Z., Dos Santos, C., Chen, S., Chen, Y., Zheng, H., Wang, H., Perl, A., Guo, D. & Huang, J., Aug 15 2017, In : Cancer Research. 77, 16, p. 4402-4413 12 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Acute Myeloid Leukemia
Protein-Tyrosine Kinases
Genome
Genes
12 Citations (Scopus)

Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

Zhu, L., Kong, Y., Zhang, J., Claxton, D. F., Ehmann, W. C., Rybka, W. B., Palmisiano, N. D., Wang, M., Jia, B., Bayerl, M., Schell, T. D., Hohl, R. J., Zeng, H. & Zheng, H., Jun 19 2017, In : Journal of Hematology and Oncology. 10, 1, 124.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
B-Lymphocytes
Up-Regulation
T-Lymphocytes
Proteins
2 Citations (Scopus)

Nanoparticle-Programmed Surface for Drug Release and Cell Regulation via Reversible Hybridization Reaction

Jiang, P., Li, S., Lai, J., Zheng, H., Lin, C., Shi, P. & Wang, Y., Feb 8 2017, In : ACS Applied Materials and Interfaces. 9, 5, p. 4467-4474 8 p.

Research output: Contribution to journalArticle

Nanoparticles
Pharmaceutical Preparations
Stents
Oligonucleotides
Drug delivery
2016
21 Citations (Scopus)

Expression of PD-1 on CD4+ T cells in peripheral blood associates with poor clinical outcome in non-small cell lung cancer

Zheng, H., Liu, X., Zhang, J., Rice, S. J., Wagman, M., Kong, Y., Zhu, L., Zhu, J., Joshi, M. & Belani, C., Jan 1 2016, In : Oncotarget. 7, 35, p. 56233-56240 8 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Cell Death
T-Lymphocytes
Neoplasms
Blocking Antibodies
5 Citations (Scopus)

Novel immunotherapies for hematological malignancies

Vasekar, M., Rizvi, S., Liu, X., Vrana, K. & Zheng, H., Aug 1 2016, In : Current Molecular Pharmacology. 9, 3, p. 264-271 8 p.

Research output: Contribution to journalReview article

Hematologic Neoplasms
Immunotherapy
T-Lymphocytes
Neoplasms
Antigen Presentation
55 Citations (Scopus)

T-cell immunoglobulin and ITIM domain (TIGIT) associates with CD8+ T-cell exhaustion and poor clinical outcome in AML patients

Kong, Y., Zhu, L., Schell, T., Zhang, J., Claxton, D., Ehmann, W. C., Rybka, W., George, M., Zeng, H. & Zheng, H., Jun 15 2016, In : Clinical Cancer Research. 22, 12, p. 3057-3066 10 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Tyrosine
Immunoglobulins
T-Lymphocytes
Leukemia
4 Citations (Scopus)
Open Access
Common Variable Immunodeficiency
Hodgkin Disease
Chemotherapy
Blood
Lymphoma
2015
44 Citations (Scopus)
Stem Cell Transplantation
Leukemia
T-Lymphocytes
Recurrence
Programmed Cell Death 1 Receptor
2014
7 Citations (Scopus)

Targeted immunotherapy for non-small cell lung cancer

Vasekar, M., Liu, X., Zheng, H. & Belani, C., May 10 2014, In : World Journal of Clinical Oncology. 5, 2, p. 39-47 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Immunotherapy
Therapeutics
Melanoma
Neoplasms
2011
27 Citations (Scopus)

Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVLand immune reconstitution

Li, N., Matte-Martone, C., Zheng, H., Cui, W., Venkatesan, S., Tan, H. S., McNiff, J., Demetris, A. J., Roopenian, D., Kaech, S. & Shlomchik, W. D., Nov 24 2011, In : Blood. 118, 22, p. 5965-5976 12 p.

Research output: Contribution to journalArticle

Minor Histocompatibility Antigens
T-cells
Viruses
T-Lymphocytes
Data storage equipment
2009
55 Citations (Scopus)

Central memory CD8+ T cells induce graft-versus-host disease and mediate graft-versus-leukemia

Zheng, H., Matte-Martone, C., Jain, D., McNiff, J. & Shlomchik, W. D., May 15 2009, In : Journal of Immunology. 182, 10, p. 5938-5948 11 p.

Research output: Contribution to journalArticle

Graft vs Host Disease
Leukemia
T-Lymphocytes
Transplants
Isoantigens
2008
109 Citations (Scopus)

Effector memory CD4+ T cells mediate graft-versus-leukemia without inducing graft-versus-host disease

Zheng, H., Matte-Martone, C., Li, H., Anderson, B. E., Venketesan, S., Hung, S. T., Jain, D., McNiff, J. & Shlomchik, W. D., Feb 15 2008, In : Blood. 111, 4, p. 2476-2484 9 p.

Research output: Contribution to journalArticle

T-cells
Graft vs Host Disease
Grafts
Leukemia
T-Lymphocytes
10 Citations (Scopus)

Memory T cells in GVHD and GVL.

Anderson, B. E., Zheng, H., Taylor, P. A., Matte-Martone, C., McNiff, J. M., Jain, D., Demetris, A. J., Panoskaltsis-Mortari, A., Ager, A., Blazar, B. R., Shlomchik, M. J. & Shlomchik, W. D., Jan 1 2008, In : Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 14, 1 Suppl 1, p. 19-20 2 p.

Research output: Contribution to journalReview article

Graft vs Leukemia Effect
Immunologic Memory
Hematopoietic Stem Cell Transplantation
Graft vs Host Disease
T-Lymphocytes
2004
43 Citations (Scopus)
Cross-Priming
Heat-Shock Proteins
Shock
Transcription Factors
Hot Temperature
2003
145 Citations (Scopus)
Heat-Shock Proteins
Endoplasmic Reticulum
Dendritic Cells
Autoimmune Diseases
Myeloid Differentiation Factor 88
62 Citations (Scopus)

Cell surface expression of heat shock protein gp96 enhances cross-presentation of cellular antigens and the generation of tumor-specific T cell memory

Dai, J., Liu, B., Caudill, M. M., Zheng, H., Qiao, Y., Podack, E. R. & Li, Z., Jan 28 2003, In : Cancer Immunity. 3, p. 1-11 11 p.

Research output: Contribution to journalArticle

Cross-Priming
Neoplasm Antigens
Heat-Shock Proteins
Ovalbumin
T-Lymphocytes
21 Citations (Scopus)
Heat-Shock Response
Dendritic Cells
Shock
Hot Temperature
Cytoprotection
2002
48 Citations (Scopus)
Antigen-Presenting Cells
Heat-Shock Proteins
Peptides
Cross-Priming
T-cells
2001
131 Citations (Scopus)

Cell surface targeting of heat shock protein gp96 induces dendritic cell maturation and antitumor immunity

Zheng, H., Dai, J., Stoilova, D. & Li, Z., Dec 15 2001, In : Journal of Immunology. 167, 12, p. 6731-6735 5 p.

Research output: Contribution to journalArticle

Heat-Shock Proteins
Dendritic Cells
Immunity
Adaptive Immunity
Chemokine CCL2