• 6982 Citations
  • 22 h-Index
1986 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
2020

Intracellular vesicle clusters are organelles that synthesize extracellular vesicle-associated cargo proteins in yeast

Winters, C. M., Hong-Brown, L. Q. & Chiang, H. L., Feb 28 2020, In : Journal of Biological Chemistry. 295, 9, p. 2650-2663 14 p.

Research output: Contribution to journalArticle

2017

The Shape of Vesicle-Containing Organelles Is Critical for Their Functions in Vesicle Endocytosis

Winters, C. M., Hong-Brown, L. Q. & Chiang, H. L., Nov 2017, In : DNA and Cell Biology. 36, 11, p. 909-921 13 p.

Research output: Contribution to journalArticle

2 Scopus citations
4 Scopus citations
2016

Yeast as a model system to study trafficking of small vesicles carrying signal-less proteins in and out of the cell

Winters, C. M. & Chiang, H. L., Jan 1 2016, In : Current Protein and Peptide Science. 17, 8, p. 808-820 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Glucose induces rapid changes in the secretome of Saccharomyces cerevisiae

Giardina, B. J., Stanley, B. A. & Chiang, H. L., Feb 12 2014, In : Proteome Science. 12, 1, 9.

Research output: Contribution to journalArticle

27 Scopus citations
11 Scopus citations
2013
8 Scopus citations
9 Scopus citations
2012
14 Scopus citations

Vid30 is required for the association of Vid vesicles and actin patches in the vacuole import and degradation pathway

Alibhoy, A. A., Giardina, B. J., Dunton, D. D. & Chiang, H. L., Jan 2012, In : Autophagy. 8, 1, p. 29-46 18 p.

Research output: Contribution to journalArticle

21 Scopus citations

Vps34p is required for the decline of extracellular fructose-1,6- bisphosphatase in the vacuole import and degradation pathway

Alibhoy, A. A., Giardina, B. J., Dunton, D. D. & Chiang, H. L., Sep 21 2012, In : Journal of Biological Chemistry. 287, 39, p. 33080-33093 14 p.

Research output: Contribution to journalArticle

16 Scopus citations
2010
21 Scopus citations
22 Scopus citations
2008

The vacuolar import and degradation pathway merges with the endocytic pathway to deliver fructose-1,6-bisphosphatase to the vacuole for degradation

Brown, C. R., Wolfe, A. B., Cui, D. & Chiang, H. L., Sep 19 2008, In : Journal of Biological Chemistry. 283, 38, p. 26116-26127 12 p.

Research output: Contribution to journalArticle

30 Scopus citations
2005

Degradation of the gluconeogenic enzyme fructose-1, 6-bisphosphatase is dependent on the vacuolar ATPase.

Liu, J., Brown, C. R. & Chiang, H. L., Jan 1 2005, In : Autophagy. 1, 3, p. 146-156 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2004

Degradation of the ghiconeogenic enzymes fructose-1,6-bisphosphatase and malate dehydrogenase is mediated by distinct proteolytic pathways and signaling events

Hung, G. C., Brown, C. R., Wolfe, A. B., Liu, J. & Chiang, H. L., Nov 19 2004, In : Journal of Biological Chemistry. 279, 47, p. 49138-49150 13 p.

Research output: Contribution to journalArticle

72 Scopus citations

The Type 1 Phosphatase Reg1p-Glc7p Is Required for the Glucose-induced Degradation of Fructose-1,6-bisphosphatase in the Vacuole

Cui, D. Y., Brown, C. R. & Chiang, H. L., Mar 12 2004, In : Journal of Biological Chemistry. 279, 11, p. 9713-9724 12 p.

Research output: Contribution to journalArticle

18 Scopus citations
2003

The Vid vesicle to vacuole trafficking event requires components of the SNARE membrane fusion machinery

Brown, C. R., Liu, J., Hung, G. C., Carter, D., Cui, D. & Chiang, H. L., Jul 11 2003, In : Journal of Biological Chemistry. 278, 28, p. 25688-25699 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
2002

Vid22p, a novel plasma membrane protein, is required for the fructose-1, 6-bisphosphatase degradation pathway

Randell Brown, C., McCann, J. A., Hung, G. G. C., Elco, C. P. & Chiang, H. L., Feb 1 2002, In : Journal of Cell Science. 115, 3, p. 655-666 12 p.

Research output: Contribution to journalArticle

33 Scopus citations
2001

Biochemical Analysis of Fructose-1,6-bisphosphatase Import into Vacuole Import and Degradation Vesicles Reveals a Role for UBC1 in Vesicle Biogenesis

Shieh, H. L., Chen, Y., Brown, C. R. & Chiang, H. L., Mar 30 2001, In : Journal of Biological Chemistry. 276, 13, p. 10398-10406 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Cyclophilin A Mediates Vid22p Function in the Import of Fructose-1,6-bisphosphatase into Vid Vesicles

Brown, C. R., Cui, D. Y., Hung, G. G. C. & Chiang, H. L., Dec 21 2001, In : Journal of Biological Chemistry. 276, 51, p. 48017-48026 10 p.

Research output: Contribution to journalArticle

51 Scopus citations
2000

The heat shock protein Ssa2p is required for import of fructose-1,6- bisphosphatase into Vid vesicles

Randell Brown, C., McCann, J. A. & Chiang, H. L., Jul 10 2000, In : Journal of Cell Biology. 150, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

60 Scopus citations
1998
36 Scopus citations
60 Scopus citations
1997

Identification of novel vesicles in the cytosol to vacuole protein degradation pathway

Huang, P. H. & Chiang, H. L., Mar 11 1997, In : Journal of Cell Biology. 136, 4, p. 803-810 8 p.

Research output: Contribution to journalArticle

75 Scopus citations
1996

Selective uptake of cytosolic, peroxisomal, and plasma membrane proteins into the yeast lysosome for degradation

Chiang, H., Schekman, R. & Hamamoto, S., Apr 26 1996, In : Journal of Biological Chemistry. 271, 17, p. 9934-9941 8 p.

Research output: Contribution to journalArticle

87 Scopus citations
1992

Mechanism and regulation of import and degradation of cytosolic proteins in the lysosome/vacuole

Chiang, H. L. & Schekman, R., Jan 1 1992, In : New Comprehensive Biochemistry. 22, C, p. 149-164 16 p.

Research output: Contribution to journalArticle

Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein

Terlecky, S. R., Chiang, H., Olson, T. S. & Dice, J. F., May 5 1992, In : Journal of Biological Chemistry. 267, 13, p. 9202-9209 8 p.

Research output: Contribution to journalArticle

150 Scopus citations
1991

Proteins containing peptide sequences related to Lys-Phe-Glu-Arg-Gln are selectively depleted in liver and heart, but not skeletal muscle, of fasted rats

Wing, S. S., Chiang, H. L., Goldberg, A. L. & Dice, J. F., Jan 1 1991, In : Biochemical Journal. 275, 1, p. 165-169 5 p.

Research output: Contribution to journalArticle

102 Scopus citations

Regulated import and degradation of a cytosolic protein in the yeast vacuole

Chiang, H. L. & Schekman, R., Jan 1 1991, In : Nature. 350, 6316, p. 313-318 6 p.

Research output: Contribution to journalArticle

123 Scopus citations
1989

A role for a 70-kilodaton heat shock protein in lysosomal degradation of intracellular proteins

Chiang, H. L., Terlecky, S. R., Plant, C. P. & Dice, J. F., Jan 1 1989, In : Science. 246, 4928, p. 382-385 4 p.

Research output: Contribution to journalArticle

607 Scopus citations

Peptide signals for protein degradation within lysosomes

Dice, J. F. & Chiang, H. L., Jan 1 1989, In : Biochemical Society Symposia. 55, p. 45-55 11 p.

Research output: Contribution to journalArticle

26 Scopus citations
1988

Peptide sequences that target proteins for enhanced degradation during serum withdrawal

Chiang, H. & Dice, J. F., Jan 1 1988, In : Journal of Biological Chemistry. 263, 14, p. 6797-6805 9 p.

Research output: Contribution to journalArticle

162 Scopus citations
1987

Lysosomal degradation of microinjected proteins.

Dice, J. F., Backer, J. M., Chiang, H. & Goff, S. A., Jan 1 1987, In : Biochemical Society Transactions. 15, 5, p. 824-826 3 p.

Research output: Contribution to journalArticle

4 Scopus citations
1986

Regulation of catabolism of microinjected ribonuclease A. Identification of residues 7-11 as the essential pentapeptide

Dice, J. F., Chiang, H., Spencer, E. P. & Backer, J. M., Dec 1 1986, In : Journal of Biological Chemistry. 261, 15, p. 6853-6859 7 p.

Research output: Contribution to journalArticle

65 Scopus citations