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Ian Simpson, PhD

    • 9921 Citations
    • 55 h-Index
    1976 …2019
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    • 6 Similar Profiles
    Facilitative Glucose Transport Proteins Medicine & Life Sciences
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    Brain Medicine & Life Sciences
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    Cell membranes Chemical Compounds
    Blood-Brain Barrier Medicine & Life Sciences

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    Projects 2003 2017

    GLUCOSE TRANSPORT IN MAMMALIAN BRAIN

    Simpson, I. & Simpson, I.

    National Institutes of Health

    Project: Research project

    Facilitative Glucose Transport Proteins
    Glucose
    Brain
    Glucose Transporter Type 1
    Blood-Brain Barrier

    Mechanisms and Regulation of Brain Iron Uptake

    Connor, J. & Simpson, I.

    National Institutes of Health

    9/30/11 → 6/30/17

    Project: Research project

    Iron
    Brain
    Endothelial Cells
    Microvessels
    Extracellular Fluid

    Thyroid hormone in patients with insulin receptor mutations

    Simpson, I. & Brown, R.

    National Institutes of Health

    1/1/07 → 12/31/12

    Project: Research project

    Wound Healing
    Stroke
    Brain
    Hyperglycemia
    Leptin

    Blood-Brain Barrier Nutrient Transport

    Simpson, I.

    National Institutes of Health

    4/1/03 → 3/31/07

    Project: Research project

    Blood-Brain Barrier
    Microvessels
    Food
    Iron
    Brain

    Research Output 1976 2019

    • 9921 Citations
    • 55 h-Index
    • 128 Article
    • 5 Review article
    • 3 Chapter
    • 1 Letter
    8 Citations (Scopus)

    Endothelial cells are critical regulators of iron transport in a model of the human blood–brain barrier

    Chiou, B., Neal, E. H., Bowman, A. B., Lippmann, E. S., Simpson, I. A. & Connor, J. R., Nov 1 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 11, p. 2117-2131 15 p.

    Research output: Contribution to journal › Article

    Iron
    Endothelial Cells
    Brain
    Apoferritins
    Transferrin

    Transferrin and H-ferritin involvement in brain iron acquisition during postnatal development: impact of sex and genotype

    Chiou, B., Neely, E. B., Mcdevitt, D. S., Simpson, I. & Connor, J., Jan 1 2019, (Accepted/In press) In : Journal of neurochemistry.

    Research output: Contribution to journal › Article

    Apoferritins
    Sexual Development
    Transferrin
    Brain
    Iron
    6 Citations (Scopus)

    A role for sex and a common HFE gene variant in brain iron uptake

    Duck, K. A., Neely, E. B., Simpson, I. & Connor, J., Mar 1 2018, In : Journal of Cerebral Blood Flow and Metabolism. 38, 3, p. 540-548 9 p.

    Research output: Contribution to journal › Article

    Iron
    Brain
    Genes
    Mutation
    Genotype
    6 Citations (Scopus)

    Pharmaceutical iron formulations do not cross a model of the human blood-brain barrier

    Chiou, B., Neal, E. H., Bowman, A. B., Lippmann, E. S., Simpson, I. A. & Connor, J. R., Jun 2018, In : PloS one. 13, 6, e0198775.

    Research output: Contribution to journal › Article

    Drug Compounding
    blood-brain barrier
    Blood-Brain Barrier
    Iron
    iron
    2 Citations (Scopus)

    The role of HFE genotype in macrophage phenotype

    Nixon, A. M., Neely, E., Simpson, I. A. & Connor, J. R., Feb 1 2018, In : Journal of Neuroinflammation. 15, 1, 30.

    Research output: Contribution to journal › Article

    Iron
    Macrophages
    Genotype
    Phenotype
    Homeostasis