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Personal profile

Research interests

Dr. Jeffrey Peters’ laboratory studies the role of the peroxisome proliferator-activated receptors (PPARs). PPARs modulate gene expression through direct and indirect mechanisms. His laboratory group uses genetically modified mouse and human models, high affinity agonists, antagonists and selective, repressive ligands to delineate the roles of PPARs, with a particular interest in cancers. Through their studies, they are elucidating the molecular mechanisms by which exogenous (dietary) and endogenous (metabolic sources) lipids specifically modulate human health. They are particularly interested in delineating how natural compounds can modulate PPARs with the goal of identifying new molecules/proteins that can be targeted with existing approaches to improve the efficacy of chemoprevention and chemotherapy.

Education/Academic qualification

Post-doctoral training, Laboratory of Molecular Carcinogenesis and Laboratory of Metabolism, National Cancer Institute


Post-doctoral training, University of California


External positions

Fellow, Academy of Toxicological Sciences

Jan 1 2012 → …

Fellow, Academy of Toxicological Sciences

2012 → …

Fingerprint Dive into the research topics where Jeffrey Maurice Peters is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Peroxisome Proliferator-Activated Receptors Medicine & Life Sciences
Peroxisome Proliferators Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Liver Medicine & Life Sciences
Ligands Medicine & Life Sciences
PPAR alpha Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Chemical activation Chemical Compounds

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Projects 2001 2019

Peroxisome Proliferator-Activated Receptors
Liver Neoplasms
Kupffer Cells
Aryl Hydrocarbon Receptors
Polycyclic Aromatic Hydrocarbons
Peroxisome Proliferator-Activated Receptors
Environmental Exposure
Aryl Hydrocarbon Receptors
Peroxisome Proliferator-Activated Receptors
Polycyclic Aromatic Hydrocarbons
Phase I Metabolic Detoxication
Peroxisome Proliferator-Activated Receptors
Skin Neoplasms
Ultraviolet Rays
Peroxisome Proliferator-Activated Receptors
Colonic Neoplasms

Research Output 1988 2019

Continuing a Legacy: Adapting to Ensure the Bright Future of ToxSci

Peters, J. M., Jul 1 2019, In : Toxicological Sciences. 170, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Interplay Between the Host, the Human Microbiome, and Drug Metabolism

Nichols, R. G., Peters, J. M. & Patterson, A. D., Jun 11 2019, In : Human genomics. 13, 1, 1 p.

Research output: Contribution to journalReview article

Open Access
Pharmaceutical Preparations
Carboxylic Ester Hydrolases
Bacterial Vaginosis

Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer

Peters, J. M., Kim, D. J., Bility, M. T., Borland, M. G., Zhu, B. & Gonzalez, F. J., Jan 1 2019, In : Molecular Carcinogenesis. 58, 9, p. 1612-1622 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Skin Neoplasms
Endoplasmic Reticulum Stress
Cell Aging
6 Citations (Scopus)

Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells

Borland, M. G., Kehres, E. M., Lee, C., Wagner, A. L., Shannon, B. E., Albrecht, P. P., Zhu, B., Gonzalez, F. J. & Peters, J. M., Jul 1 2018, In : Toxicology. 404-405, p. 25-32 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Cell Cycle
15 Citations (Scopus)

Lipid metabolism and lipophagy in cancer

Maan, M., Peters, J. M., Dutta, M. & Patterson, A. D., Oct 7 2018, In : Biochemical and Biophysical Research Communications. 504, 3, p. 582-589 8 p.

Research output: Contribution to journalArticle

Lipid Metabolism

Activities 2005 2016

  • 3 Oral presentation