Projects per year
Personal profile
Research interests
Dr. Jeffrey Peters’ laboratory studies the role of the peroxisome proliferator-activated receptors (PPARs). PPARs modulate gene expression through direct and indirect mechanisms. His laboratory group uses genetically modified mouse and human models, high affinity agonists, antagonists and selective, repressive ligands to delineate the roles of PPARs, with a particular interest in cancers. Through their studies, they are elucidating the molecular mechanisms by which exogenous (dietary) and endogenous (metabolic sources) lipids specifically modulate human health. They are particularly interested in delineating how natural compounds can modulate PPARs with the goal of identifying new molecules/proteins that can be targeted with existing approaches to improve the efficacy of chemoprevention and chemotherapy.
Education/Academic qualification
Post-doctoral training, Laboratory of Molecular Carcinogenesis and Laboratory of Metabolism, National Cancer Institute
1995 → 1999
Post-doctoral training, University of California
1992 → 1995
External positions
Fellow, Academy of Toxicological Sciences
Jan 1 2012 → …Fellow, Academy of Toxicological Sciences
2012 → …Fingerprint Dive into the research topics where Jeffrey Maurice Peters is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 5 Similar Profiles
Peroxisome Proliferator-Activated Receptors
Medicine & Life Sciences
Peroxisome Proliferators
Medicine & Life Sciences
Carcinogenesis
Medicine & Life Sciences
Liver
Medicine & Life Sciences
Ligands
Medicine & Life Sciences
PPAR alpha
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Chemical activation
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2001 2019
- 6 Finished
PPAR-beta
Peroxisome Proliferator-Activated Receptors
Liver Neoplasms
Epigenomics
Kupffer Cells
Transcriptional regulation of polycyclic aromatic hydrocarbon metabolism
1/1/10 → 11/30/14
Project: Research project
Aryl Hydrocarbon Receptors
Polycyclic Aromatic Hydrocarbons
Peroxisome Proliferator-Activated Receptors
Xenobiotics
Environmental Exposure
Aryl Hydrocarbon Receptors
Peroxisome Proliferator-Activated Receptors
Polycyclic Aromatic Hydrocarbons
Keratinocytes
Phase I Metabolic Detoxication
Peroxisome Proliferator-Activated Receptors
Skin Neoplasms
Ultraviolet Rays
Ligands
Skin
PPAR-beta
Peroxisome Proliferator-Activated Receptors
Colon
Carcinogenesis
Colonic Neoplasms
Research Output 1988 2019
Continuing a Legacy: Adapting to Ensure the Bright Future of ToxSci
Peters, J. M., Jul 1 2019, In : Toxicological Sciences. 170, 1, p. 1-2 2 p.Research output: Contribution to journal › Editorial
Ensure
Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer
Peters, J. M., Kim, D. J., Bility, M. T., Borland, M. G., Zhu, B. & Gonzalez, F. J., Jan 1 2019, In : Molecular Carcinogenesis. 58, 9, p. 1612-1622 11 p.Research output: Contribution to journal › Article
Peroxisome Proliferator-Activated Receptors
Skin Neoplasms
Keratinocytes
Endoplasmic Reticulum Stress
Cell Aging
5
Citations
(Scopus)
Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells
Borland, M. G., Kehres, E. M., Lee, C., Wagner, A. L., Shannon, B. E., Albrecht, P. P., Zhu, B., Gonzalez, F. J. & Peters, J. M., Jul 1 2018, In : Toxicology. 404-405, p. 25-32 8 p.Research output: Contribution to journal › Article
Peroxisome Proliferator-Activated Receptors
Skin
Cell Cycle
Carcinogenesis
Cells
11
Citations
(Scopus)
Lipid metabolism and lipophagy in cancer
Maan, M., Peters, J. M., Dutta, M. & Patterson, A. D., Oct 7 2018, In : Biochemical and Biophysical Research Communications. 504, 3, p. 582-589 8 p.Research output: Contribution to journal › Article
Lipid Metabolism
Tumors
Neoplasms
Lipids
Cells
1
Citation
(Scopus)
Molecular Regulation of Carcinogenesis: Friend and Foe
Patterson, A. D., Gonzalez, F. J., Perdew, G. H. & Peters, J. M., Oct 1 2018, In : Toxicological Sciences. 165, 2, p. 277-283 7 p.Research output: Contribution to journal › Review article
Cell signaling
T-Cell Antigen Receptor
Medicine
Explosions
Tumors
Activities 2005 2016
- 3 Oral presentation
Unraveling the controversial role of peroxisome proliferator-activated receptor-β/δ in cancer
Jeffrey Maurice Peters (Keynote speaker)2016 → …
Activity: Talk types › Oral presentation
Peroxisome proliferator-activated receptors as molecular targets for the treatment and prevention of diseases
Jeffrey Maurice Peters (Invited speaker)2009 → …
Activity: Talk types › Oral presentation
PPARβ(δ)-dependent regulation of cell proliferation, differentiation and carcinogenesis: Studies from null mouse models
Jeffrey Maurice Peters (Invited speaker)2005 → …
Activity: Talk types › Oral presentation