If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Research interests

Dr. Jeffrey Peters’ laboratory studies the role of the peroxisome proliferator-activated receptors (PPARs). PPARs modulate gene expression through direct and indirect mechanisms. His laboratory group uses genetically modified mouse and human models, high affinity agonists, antagonists and selective, repressive ligands to delineate the roles of PPARs, with a particular interest in cancers. Through their studies, they are elucidating the molecular mechanisms by which exogenous (dietary) and endogenous (metabolic sources) lipids specifically modulate human health. They are particularly interested in delineating how natural compounds can modulate PPARs with the goal of identifying new molecules/proteins that can be targeted with existing approaches to improve the efficacy of chemoprevention and chemotherapy.

Education/Academic qualification

Post-doctoral training, Laboratory of Molecular Carcinogenesis and Laboratory of Metabolism, National Cancer Institute

19951999

Post-doctoral training, University of California

19921995

External positions

Fellow, Academy of Toxicological Sciences

Jan 1 2012 → …

Fellow, Academy of Toxicological Sciences

2012 → …

Fingerprint Dive into the research topics where Jeffrey Maurice Peters is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Peroxisome Proliferator-Activated Receptors Medicine & Life Sciences
Peroxisome Proliferators Medicine & Life Sciences
Carcinogenesis Medicine & Life Sciences
Liver Medicine & Life Sciences
Ligands Medicine & Life Sciences
PPAR alpha Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Chemical activation Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2001 2019

PPAR-beta
Peroxisome Proliferator-Activated Receptors
Liver Neoplasms
Epigenomics
Kupffer Cells
Aryl Hydrocarbon Receptors
Polycyclic Aromatic Hydrocarbons
Peroxisome Proliferator-Activated Receptors
Xenobiotics
Environmental Exposure
Aryl Hydrocarbon Receptors
Peroxisome Proliferator-Activated Receptors
Polycyclic Aromatic Hydrocarbons
Keratinocytes
Phase I Metabolic Detoxication
Peroxisome Proliferator-Activated Receptors
Skin Neoplasms
Ultraviolet Rays
Ligands
Skin
PPAR-beta
Peroxisome Proliferator-Activated Receptors
Colon
Carcinogenesis
Colonic Neoplasms

Research Output 1988 2019

Continuing a Legacy: Adapting to Ensure the Bright Future of ToxSci

Peters, J. M., Jul 1 2019, In : Toxicological Sciences. 170, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Ensure

Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer

Peters, J. M., Kim, D. J., Bility, M. T., Borland, M. G., Zhu, B. & Gonzalez, F. J., Jan 1 2019, In : Molecular Carcinogenesis. 58, 9, p. 1612-1622 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Skin Neoplasms
Keratinocytes
Endoplasmic Reticulum Stress
Cell Aging
5 Citations (Scopus)

Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells

Borland, M. G., Kehres, E. M., Lee, C., Wagner, A. L., Shannon, B. E., Albrecht, P. P., Zhu, B., Gonzalez, F. J. & Peters, J. M., Jul 1 2018, In : Toxicology. 404-405, p. 25-32 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Skin
Cell Cycle
Carcinogenesis
Cells
11 Citations (Scopus)

Lipid metabolism and lipophagy in cancer

Maan, M., Peters, J. M., Dutta, M. & Patterson, A. D., Oct 7 2018, In : Biochemical and Biophysical Research Communications. 504, 3, p. 582-589 8 p.

Research output: Contribution to journalArticle

Lipid Metabolism
Tumors
Neoplasms
Lipids
Cells
1 Citation (Scopus)

Molecular Regulation of Carcinogenesis: Friend and Foe

Patterson, A. D., Gonzalez, F. J., Perdew, G. H. & Peters, J. M., Oct 1 2018, In : Toxicological Sciences. 165, 2, p. 277-283 7 p.

Research output: Contribution to journalReview article

Cell signaling
T-Cell Antigen Receptor
Medicine
Explosions
Tumors

Activities 2005 2016

  • 3 Oral presentation