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Research Output 1988 2019

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2019

Regulatory mechanisms mediated by peroxisome proliferator-activated receptor-β/δ in skin cancer

Peters, J. M., Kim, D. J., Bility, M. T., Borland, M. G., Zhu, B. & Gonzalez, F. J., Jan 1 2019, In : Molecular Carcinogenesis. 58, 9, p. 1612-1622 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Skin Neoplasms
Keratinocytes
Endoplasmic Reticulum Stress
Cell Aging
2018
6 Citations (Scopus)

Inhibition of tumorigenesis by peroxisome proliferator-activated receptor (PPAR)-dependent cell cycle blocks in human skin carcinoma cells

Borland, M. G., Kehres, E. M., Lee, C., Wagner, A. L., Shannon, B. E., Albrecht, P. P., Zhu, B., Gonzalez, F. J. & Peters, J. M., Jul 1 2018, In : Toxicology. 404-405, p. 25-32 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Skin
Cell Cycle
Carcinogenesis
Cells
15 Citations (Scopus)

Lipid metabolism and lipophagy in cancer

Maan, M., Peters, J. M., Dutta, M. & Patterson, A. D., Oct 7 2018, In : Biochemical and Biophysical Research Communications. 504, 3, p. 582-589 8 p.

Research output: Contribution to journalArticle

Lipid Metabolism
Tumors
Neoplasms
Lipids
Cells
2017
1 Citation (Scopus)

Four-week dietary supplementation with 10- and/or 15-fold basal choline caused decreased body weight in Sprague Dawley rats

Bagley, B. D., Chang, S. C., Ehresman, D. J., Eveland, A., Parker, G. A., Peters, J. M. & Butenhoff, J. L., Oct 1 2017, In : Toxicology and Industrial Health. 33, 10, p. 792-801 10 p.

Research output: Contribution to journalArticle

Dietary Supplements
Choline
Sprague Dawley Rats
Rats
Body Weight
3 Citations (Scopus)

Isolation, characterization, and purification of macrophages from tissues affected by obesity-related inflammation

Allen, J. N., Dey, A., Nissly, R., Fraser, J., Yu, S., Balandaram, G., Peters, J. M. & Hankey-Giblin, P. A., Apr 3 2017, In : Journal of Visualized Experiments. 2017, 122, e55445.

Research output: Contribution to journalArticle

Macrophages
Purification
Obesity
Tissue
Inflammation
3 Citations (Scopus)

Perfluorooctane sulfonate-induced hepatic steatosis in male sprague dawley rats is not attenuated by dietary choline supplementation

Bagley, B. D., Chang, S. C., Ehresman, D. J., Eveland, A., Zitzow, J. D., Parker, G. A., Peters, J. M., Wallace, K. B. & Butenhoff, J. L., Dec 1 2017, In : Toxicological Sciences. 160, 2, p. 284-298 15 p.

Research output: Contribution to journalArticle

Dietary Supplements
Choline
Sprague Dawley Rats
Rats
Liver
8 Citations (Scopus)

Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation

Yao, P. L., Chen, L., Dobrzański, T. P., Zhu, B., Kang, B. H., Müller, R., Gonzalez, F. J. & Peters, J. M., May 1 2017, In : Molecular Carcinogenesis. 56, 5, p. 1472-1483 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Neuroblastoma
Cell Differentiation
Carcinogenesis
Tretinoin
1 Citation (Scopus)

Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype

Yao, P. L., Morales, J. L., Gonzalez, F. J. & Peters, J. M., Apr 1 2017, In : Immunology. 150, 4, p. 456-467 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Mast Cells
Phenotype
Bone and Bones
Cytokines
6 Citations (Scopus)

PPARβ/δ and PPARγ inhibit melanoma tumorigenicity by modulating inflammation and apoptosis

Borland, M. G., Yao, P. L., Kehres, E. M., Lee, C., Pritzlaff, A. M., Ola, E., Wagner, A. L., Shannon, B. E., Albrecht, P. P., Zhu, B., Kang, B. H., Robertson, G. P., Gonzalez, F. J. & Peters, J. M., Oct 1 2017, In : Toxicological Sciences. 159, 2, p. 436-448 13 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Melanoma
Apoptosis
Inflammation
Cells
2016
4 Citations (Scopus)

Ligand activation of peroxisome proliferator-activated receptor-β/δ suppresses liver tumorigenesis in hepatitis B transgenic mice

Balandaram, G., Kramer, L. R., Kang, B. H., Murray, I. A., Perdew, G. H., Gonzalez, F. J. & Peters, J. M., Jul 1 2016, In : Toxicology. 363-364, p. 1-9 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Hepatitis B
Liver
Transgenic Mice
Carcinogenesis
5 Citations (Scopus)

Perfluorooctane sulfonate-choline ion pair formation: A potential mechanism modulating hepatic steatosis and oxidative stress in mice

Zhang, L., Krishnan, P., Ehresman, D. J., Smith, P. B., Dutta, M., Bagley, B. D., Chang, S. C., Butenhoff, J. L., Patterson, A. D. & Peters, J. M., Sep 1 2016, In : Toxicological Sciences. 153, 1, p. 186-197 12 p., kfw120.

Research output: Contribution to journalArticle

Oxidative stress
Choline
Oxidative Stress
Ions
Liver
6 Citations (Scopus)

PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration

Choudhary, M., Ding, J. D., Qi, X., Boulton, M. E., Yao, P. L., Peters, J. M. & Malek, G., Jan 1 2016, In : Aging. 8, 9, p. 1952-1978 27 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Macular Degeneration
Retinal Pigments
Cytoplasmic and Nuclear Receptors
Lipid Metabolism
5 Citations (Scopus)

Regulation of cytochrome P450 2B10 (CYP2B10) expression in liver by peroxisome proliferator-activated receptor-β/δ modulation of SP1 promoter occupancy

Koga, T., Yao, P. L., Goudarzi, M., Murray, I. A., Balandaram, G., Gonzalez, F. J., Perdew, G. H., Fornace, A. J. & Peters, J. M., Nov 25 2016, In : Journal of Biological Chemistry. 291, 48, p. 25255-25263 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Liver
Cytochrome P-450 Enzyme System
Modulation
Ethanol
8 Citations (Scopus)

The ron receptor tyrosine kinase regulates macrophage heterogeneity and plays a protective role in diet-induced obesity, atherosclerosis, and hepatosteatosis

Yu, S., Allen, J. N., Dey, A., Zhang, L., Balandaram, G., Kennett, M. J., Xia, M., Xiong, N., Peters, J. M., Patterson, A. D. & Giblin, P. H., Jul 1 2016, In : Journal of Immunology. 197, 1, p. 256-265 10 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Atherosclerosis
Obesity
Macrophages
Diet
2015
7 Citations (Scopus)

Inhibition of testicular embryonal carcinoma cell tumorigenicity by peroxisome proliferator-activated receptor-β/δ- and retinoic acid receptor-dependent mechanisms

Yao, P. L., Chen, L. P., Dobrzanski, T. P., Phillips, D. A., Zhu, B., Kang, B. H., Gonzalez, F. J. & Peters, J. M., Jan 1 2015, In : Oncotarget. 6, 34, p. 36319-36337 19 p.

Research output: Contribution to journalArticle

Embryonal Carcinoma Stem Cells
Retinoic Acid Receptors
Peroxisome Proliferator-Activated Receptors
Retinoid X Receptors
Heterografts
20 Citations (Scopus)

M-CSF from cancer cells induces fatty acid synthase and PPARβ/δ activation in tumor myeloid cells, leading to tumor progression

Park, J., Lee, S. E., Hur, J., Hong, E. B., Choi, J. I., Yang, J. M., Kim, J. Y., Kim, Y. C., Cho, H. J., Peters, J. M., Ryoo, S. B., Kim, Y. T. & Kim, H. S., Mar 10 2015, In : Cell Reports. 10, 9, p. 1614-1625 12 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Peroxisome Proliferator-Activated Receptors
Macrophage Colony-Stimulating Factor
Myeloid Cells
Tumors
10 Citations (Scopus)

Peroxisome proliferator-activated receptor-D (PPARD) coordinates mouse spermatogenesis by modulating extracellular signal-regulated kinase (ERK)-dependent signaling

Yao, P. L., Chen, L. P., Hess, R. A., Müller, R., Gonzalez, F. J. & Peters, J. M., Sep 18 2015, In : Journal of Biological Chemistry. 290, 38, p. 23416-23431 16 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Extracellular Signal-Regulated MAP Kinases
Spermatogenesis
Sertoli Cells
Cyclin D2
2014
34 Citations (Scopus)

Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity

Yao, P. L., Morales, J. L., Zhu, B., Kang, B. H., Gonzalez, F. J. & Peters, J. M., Apr 2014, In : Molecular cancer therapeutics. 13, 4, p. 1008-1017 10 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Breast Neoplasms
Cell Line
Ligands
Estrogen Receptors
28 Citations (Scopus)
Aryl Hydrocarbon Receptors
Rheumatoid Arthritis
Intercellular Signaling Peptides and Proteins
Fibroblasts
Cytokines
7 Citations (Scopus)

Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid

Yao, P. L., Ehresman, D. J., Rae, J. M. C., Chang, S. C., Frame, S. R., Butenhoff, J. L., Kennedy, G. L. & Peters, J. M., Dec 4 2014, In : Toxicology. 326, p. 62-73 12 p.

Research output: Contribution to journalArticle

perfluorooctanoic acid
Estrogen Receptors
Estrogens
Luciferases
Assays
15 Citations (Scopus)

Modulation of aryl hydrocarbon receptor (AHR)-dependent signaling by peroxisome proliferator-activated receptor β/δ (PPARβ/δ) in keratinocytes

Borland, M. G., Krishnan, P., Lee, C., Albrecht, P. P., Shan, W., Bility, M. T., Marcus, C. B., Lin, J. M., Amin, S., Gonzalez, F. J., Perdew, G. H. & Peters, J. M., Jul 2014, In : Carcinogenesis. 35, 7, bgu067.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Peroxisome Proliferator-Activated Receptors
Keratinocytes
Polycyclic Aromatic Hydrocarbons
9,10-Dimethyl-1,2-benzanthracene
28 Citations (Scopus)

The nuclear receptor peroxisome proliferator-activated receptor-β/ δ (PPARβ/δ) promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress

Zhu, B., Ferry, C. H., Markell, L. K., Blazanin, N., Glick, A. B., Gonzalez, F. J. & Peters, J. M., Jan 1 2014, In : Journal of Biological Chemistry. 289, 29, p. 20102-20119 18 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Endoplasmic Reticulum Stress
Cell Aging
Cytoplasmic and Nuclear Receptors
Oncogenes
2013
25 Citations (Scopus)

A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid

Albrecht, P. P., Torsell, N. E., Krishnan, P., Ehresman, D. J., Frame, S. R., Chang, S. C., Butenhoff, J. L., Kennedy, G. L., Gonzalez, F. J. & Peters, J. M., Feb 1 2013, In : Toxicological Sciences. 131, 2, p. 568-582 15 p.

Research output: Contribution to journalArticle

perfluorooctanoic acid
Peroxisome Proliferator-Activated Receptors
Liver
Cytochrome P-450 Enzyme System
Acyl-CoA Oxidase
4 Citations (Scopus)

Cholestasis induces reversible accumulation of periplakin in mouse liver

Ito, S., Satoh, J., Matsubara, T., Shah, Y. M., Ahn, S. H., Anderson, C. R., Shan, W., Peters, J. M. & Gonzalez, F. J., Jul 13 2013, In : BMC Gastroenterology. 13, 1, 116.

Research output: Contribution to journalArticle

Cholestasis
Liver
Plakins
Kidney
Ureteral Obstruction
6 Citations (Scopus)

PPARβ/δ modulates ethanol-induced hepatic effects by decreasing pyridoxal kinase activity

Goudarzi, M., Koga, T., Khozoie, C., Mac, T. D., Kang, B. H., Fornace, A. J. & Peters, J. M., Sep 5 2013, In : Toxicology. 311, 3, p. 87-98 12 p.

Research output: Contribution to journalArticle

Pyridoxal Kinase
Peroxisome Proliferator-Activated Receptors
Alcoholic Liver Diseases
Ethanol
Metabolism
2012
28 Citations (Scopus)

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4

Khozoie, C., Borland, M. G., Zhu, B., Baek, S., John, S., Hager, G. L., Shah, Y. M., Gonzalez, F. J. & Peters, J. M., Nov 24 2012, In : BMC genomics. 13, 1, 665.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Keratinocytes
Ligands
Chromatin Immunoprecipitation
Genes
17 Citations (Scopus)

Immunomodulatory action of dietary fish oil and targeted deletion of intestinal epithelial cell PPAR δ in inflammation-induced colon carcinogenesis

Monk, J. M., Kim, W., Callaway, E., Turk, H. F., Foreman, J. E., Peters, J. M., He, W., Weeks, B., Alaniz, R. C., McMurray, D. N. & Chapkin, R. S., Jan 1 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 1, p. G153-G167

Research output: Contribution to journalArticle

Unsaturated Dietary Fats
Peroxisome Proliferator-Activated Receptors
Fish Oils
Colon
Carcinogenesis
8 Citations (Scopus)

Peroxisome proliferator-activated receptor β/δ cross talks with e2f and attenuates mitosis in HRAS-expressing cells

Zhu, B., Khozoie, C., Bility, M. T., Ferry, C. H., Blazanin, N., Glick, A. B., Gonzalez, F. J. & Peters, J. M., Jun 1 2012, In : Molecular and cellular biology. 32, 11, p. 2065-2082 18 p.

Research output: Contribution to journalArticle

Receptor Cross-Talk
Peroxisome Proliferator-Activated Receptors
Mitosis
Ligands
Keratinocytes
2011
25 Citations (Scopus)

Functional characterization of peroxisome proliferator-activated receptor-β/δ expression in colon cancer

Foreman, J. E., Chang, W. C. L., Palkar, P. S., Zhu, B., Borland, M. G., Williams, J. L., Kramer, L. R., Clapper, M. L., Gonzalez, F. J. & Peters, J. M., Nov 1 2011, In : Molecular Carcinogenesis. 50, 11, p. 884-900 17 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Colonic Neoplasms
Colon
Ligands
Apoptosis
53 Citations (Scopus)

NTP-CERHR expert panel report on the developmental toxicity of soy infant formula

McCarver, G., Bhatia, J., Chambers, C., Clarke, R., Etzel, R., Foster, W., Hoyer, P., Leeder, J. S., Peters, J. M., Rissman, E., Rybak, M., Sherman, C., Toppari, J. & Turner, K., Oct 1 2011, In : Birth Defects Research Part B - Developmental and Reproductive Toxicology. 92, 5, p. 421-468 48 p.

Research output: Contribution to journalArticle

Infant Formula
Genistein
Program Evaluation
Toxicology
Reproduction
28 Citations (Scopus)

PPARβ/δ activation induces enteroendocrine L cell GLP-1 production

Daoudi, M., Hennuyer, N., Borland, M. G., Touche, V., Duhem, C., Gross, B., Caiazzo, R., Kerrconte, J., Pattou, F., Peters, J. M., Staels, B. & Lestavel, S., May 2011, In : Gastroenterology. 140, 5, p. 1564-1574 11 p.

Research output: Contribution to journalArticle

Enteroendocrine Cells
Peroxisome Proliferator-Activated Receptors
Glucagon-Like Peptide 1
Proglucagon
Small Intestine
26 Citations (Scopus)

Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes

Borland, M. G., Khozoie, C., Albrecht, P. P., Zhu, B., Lee, C., Lahoti, T. S., Gonzalez, F. J. & Peters, J. M., Dec 1 2011, In : Cellular Signalling. 23, 12, p. 2039-2050 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Keratinocytes
Angiopoietins
Fatty Acid-Binding Proteins
Retinoic Acid Receptors
2010
11 Citations (Scopus)

A natural propenoic acid derivative activates peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

Genovese, S., Foreman, J. E., Borland, M. G., Epifano, F., Gonzalez, F. J., Curini, M. & Peters, J. M., Feb 26 2010, In : Life Sciences. 86, 13-14, p. 493-498 6 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Derivatives
Acids
Cell proliferation
Cell Proliferation
35 Citations (Scopus)

Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-β/δ antagonist GSK3787

Palkar, P. S., Borland, M. G., Naruhn, S., Ferry, C. H., Lee, C., Sk, U. H., Sharma, A., Amin, S., Murray, I. A., Anderson, C. R., Perdew, G. H., Gonzalez, F. J., Müller, R. & Peters, J. M., Jan 1 2010, In : Molecular pharmacology. 78, 3, p. 419-430 12 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Pharmacology
4-chloro-N-(2-((5-trifluoromethyl-2-pyridyl)sulfonyl)ethyl)benzamide
Colon
Cell Line
14 Citations (Scopus)

Chemoprevention of chemically induced skin tumorigenesis by ligand activation of peroxisome proliferator-activated receptor-β/δ and inhibition of cyclooxygenase 2

Zhu, B., Bai, R., Kennett, M. J., Kang, B. H., Gonzalez, F. J. & Peters, J. M., Dec 1 2010, In : Molecular cancer therapeutics. 9, 12, p. 3267-3277 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Chemoprevention
Cyclooxygenase 2
nimesulide
Carcinogenesis
7 Citations (Scopus)

Effect of prenatal peroxisome proliferator-activated receptor α (PPARα) agonism on postnatal development

Palkar, P. S., Anderson, C. R., Ferry, C. H., Gonzalez, F. J. & Peters, J. M., Sep 1 2010, In : Toxicology. 276, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Clofibrate
perfluorooctanoic acid
Mothers
Genotype
16 Citations (Scopus)

Ligand activation of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) inhibits cell growth in a mouse mammary gland cancer cell line

Foreman, J. E., Sharma, A., Amin, S., Gonzalez, F. J. & Peters, J. M., Feb 28 2010, In : Cancer Letters. 288, 2, p. 219-225 7 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Human Mammary Glands
Breast Neoplasms
Ligands
Cell Line
14 Citations (Scopus)

Regulation of oligodendrocyte progenitor cell maturation by PPARδ: Effects on bone morphogenetic proteins

Simonini, M. V., Polak, P. E., Boullerne, A. I., Peters, J. M., Richardson, J. C. & Feinstein, D. L., Mar 22 2010, In : ASN Neuro. 2, 1, p. 1-13 13 p., e00025.

Research output: Contribution to journalArticle

Bone Morphogenetic Proteins
Peroxisome Proliferator-Activated Receptors
Oligodendroglia
Stem Cells
Autoimmune Experimental Encephalomyelitis
13 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Selenium
Bioactivity
Ligands
Cell proliferation
2009
22 Citations (Scopus)

Differential hepatic effects of perfluorobutyrate mediated by mouse and human PPAR-α

Foreman, J. E., Chang, S. C., Ehresman, D. J., Butenhoff, J. L., Anderson, C. R., Palkar, P. S., Kang, B. H., Gonzalez, F. J. & Peters, J. M., Jun 29 2009, In : Toxicological Sciences. 110, 1, p. 204-211 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Liver
Hepatocytes
perfluorobutyric acid
perfluorooctanoic acid
23 Citations (Scopus)

Ligand activation of peroxisome proliferator-activated receptor-β/δ and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis

Bility, M. T., Zhu, B., Kang, B. H., Gonzalez, F. J. & Peters, J. M., Sep 11 2009, In : Toxicological Sciences. 113, 1, p. 27-36 10 p., kfp212.

Research output: Contribution to journalArticle

nimesulide
Peroxisome Proliferator-Activated Receptors
Cyclooxygenase 2
Skin
Carcinogenesis
21 Citations (Scopus)

PPARδ is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer

Ghosh, M., Ai, Y., Narko, K., Wang, Z., Peters, J. M. & Hla, T., Apr 1 2009, In : Prostaglandins and Other Lipid Mediators. 88, 3-4, p. 97-100 4 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Cyclooxygenase 2
Breast Neoplasms
Prostaglandins
Breast
12 Citations (Scopus)

Regulation of peroxisome proliferator-activated receptor-α by MDM2

Gopinathan, L., Hannon, D. B., Peters, J. M. & Vanden Heuvel, J. P., Mar 4 2009, In : Toxicological Sciences. 108, 1, p. 48-58 11 p.

Research output: Contribution to journalArticle

PPAR alpha
Peroxisome Proliferator-Activated Receptors
Lipid Metabolism
Ubiquitin-Protein Ligases
Proteins
31 Citations (Scopus)

Regulation of peroxisome proliferator-activated receptor-β/δ by the APC/β-CATENIN pathway and nonsteroidal antiinflammatory drugs

Foreman, J. E., Sorg, J. M., McGinnis, K. S., Rigas, B., Williams, J. L., Clapper, M. L., Gonzalez, F. J. & Peters, J. M., Oct 1 2009, In : Molecular Carcinogenesis. 48, 10, p. 942-952 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Adenomatous Polyposis Coli
Anti-Inflammatory Agents
Pharmaceutical Preparations
Colonic Neoplasms
2008
21 Citations (Scopus)

Effect of ligand activation of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in human lung cancer cell lines

He, P., Borland, M. G., Zhu, B., Sharma, A., Amin, S., El-Bayoumy, K., Gonzalez, F. J. & Peters, J. M., Dec 5 2008, In : Toxicology. 254, 1-2, p. 112-117 6 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Lung Neoplasms
Chemical activation
Cells
Ligands
48 Citations (Scopus)

Ligand activation of peroxisome proliferator-activated receptor-β/ δ (PPARβ/δ) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms

Hollingshead, H. E., Borland, M. G., Billin, A. N., Willson, T. M., Gonzalez, F. J. & Peters, J. M., Jan 1 2008, In : Carcinogenesis. 29, 1, p. 169-176 8 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Cyclooxygenase 2
nimesulide
Colon
Carcinogenesis
53 Citations (Scopus)

Ligand activation of peroxisome proliferator - Activated receptor β/ δ (PPARβ/δ) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression

Shan, W., Palkar, P. S., Murray, I. A., Mcdevitt, E. I., Kennett, M. J., Kang, B. H., Isom, H. C., Perdew, G. H., Gonzalez, F. J. & Peters, J. M., Sep 22 2008, In : Toxicological Sciences. 105, 2, p. 418-428 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Carbon Tetrachloride
Gene expression
Down-Regulation
Chemical activation
33 Citations (Scopus)

Ligand activation of peroxisome proliferator-activated receptor β/δ (PPARβ/δ) inhibits chemically induced skin tumorigenesis

Bility, M. T., Devlin-Durante, M. K., Blazanin, N., Glick, A. B., Ward, J. M., Kang, B. H., Kennett, M. J., Gonzalez, F. J. & Peters, J. M., Dec 15 2008, In : Carcinogenesis. 29, 12, p. 2406-2414 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Carcinogenesis
Ligands
Skin
Keratinocytes
43 Citations (Scopus)

Ligand activation of peroxisome proliferator-activated receptor-β/ δ inhibits cell proliferation in human HaCaT keratinocytes

Borland, M. G., Foreman, J. E., Girroir, E. E., Zolfaghari, R., Sharma, A., Amin, S., Gonzalez, F. J., Ross, A. C. & Peters, J. M., Nov 1 2008, In : Molecular Pharmacology. 74, 5, p. 1429-1442 14 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Keratinocytes
Tretinoin
Cell Proliferation
Ligands
72 Citations (Scopus)

Nrf2- and PPARα-mediated regulation of hepatic mrp transporters after exposure to perfluorooctanoic acid and perfluorodecanoic acid

Maher, J. M., Aleksunes, L. M., Dieter, M. Z., Tanaka, Y., Peters, J. M., Manautou, J. E. & Klaassen, C. D., Nov 28 2008, In : Toxicological Sciences. 106, 2, p. 319-328 10 p.

Research output: Contribution to journalArticle

perfluorooctanoic acid
NF-E2-Related Factor 2
PPAR alpha
Liver
Oxidative stress