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Research Output 1992 2019

2019
2 Citations (Scopus)

Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development

Hu, J., Lin, Y. Y., Chen, P. J., Watashi, K. & Wakita, T., Jan 1 2019, In : Gastroenterology. 156, 2, p. 338-354 17 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepatitis B virus
Animal Models
Pharmaceutical Preparations
Cell Culture Techniques

Chemical pressure effect on the optical conductivity of the nodal-line semimetals ZrSiY (Y= S,Se,Te) and ZrGeY (Y= S,Te)

Ebad-Allah, J., Afonso, J. F., M., K., Hu, J., Zhu, Y. L., Mao, Z. Q., J., K. & Kuntscher, C. A., 2019, In : Physical Review B. 99, 12

Research output: Contribution to journalArticle

metalloids
pressure effects
conductivity
corrugating
interlayers

HIV–HBV and HIV–HCV coinfection and liver cancer development

Hu, J., Liu, K. & Luo, J., Jan 1 2019, Cancer Treatment and Research. Springer International Publishing, p. 231-250 20 p. (Cancer Treatment and Research; vol. 177).

Research output: Chapter in Book/Report/Conference proceedingChapter

Liver Neoplasms
Coinfection
Hepatitis B virus
HIV
Hepacivirus

Secretion of empty or complete hepatitis B virions: Envelopment of empty capsids versus mature nucleocapsids

Liu, K. & Hu, J., Feb 1 2019, In : Future Virology. 14, 2, p. 95-105 11 p.

Research output: Contribution to journalReview article

Nucleocapsid
Capsid
Hepatitis B
Virion
RNA

Surface Instability and Chemical Reactivity of ZrSiS and ZrSiSe Nodal-Line Semimetals

Boukhvalov, D. W., Edla, R., Cupolillo, A., Fabio, V., Sankar, R., Zhu, Y., Mao, Z., Hu, J., Torelli, P., Chiarello, G., Ottaviano, L. & Politano, A., 2019, In : Advanced Functional Materials. 29, 18

Research output: Contribution to journalArticle

Metalloids
Chemical reactivity
metalloids
reactivity
Atoms
2018

Anisotropic ultraviolet-plasmon dispersion in black phosphorus

Nicotra, G., Van Veen, E., Deretzis, I., Wang, L., Hu, J., Mao, Z., Fabio, V., Spinella, C., Chiarello, G., Rudenko, A., Yuan, S. & Politano, A., 2018, In : Nanoscale. 10, 46, p. 21918-21927 10 p.

Research output: Contribution to journalArticle

Electron energy loss spectroscopy
Phosphorus
Plasmons
Excitation energy
Band structure
15 Citations (Scopus)

A research agenda for curing chronic hepatitis B virus infection

Alter, H., Block, T., Brown, N., Brownstein, A., Brosgart, C., Chang, K. M., Chen, P. J., Chisari, F. V., Cohen, C., El-Serag, H., Feld, J., Gish, R., Glenn, J., Greten, T., Guo, H., Guo, J. T., Hoshida, Y., Hu, J., Kowdley, K. V., Li, W. & 15 othersLiang, J., Locarnini, S., Lok, A. S., Mason, W., McMahon, B., Mehta, A., Perrillo, R., Revill, P., Rice, C. M., Rinaudo, J. A., Schinazi, R., Seeger, C., Shetty, K., Tavis, J. & Zoulim, F., Mar 1 2018, In : Hepatology. 67, 3, p. 1127-1131 5 p.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Virus Diseases
Hepatitis B virus
Research

A Triplet Resonance in Superconducting Fe1.03Se0.4Te0.6

Liu, J., Savici, A. T., Granroth, G. E., Habicht, K., Qiu, Y., Hu, J., Mao, Z. Q. & Bao, W., 2018, In : Chinese Physics Letters. 35, 12

Research output: Contribution to journalArticle

spin resonance
Group 5A compounds
chalcogenides
cuprates
inelastic scattering
3 Citations (Scopus)

common and distinct capsid and surface protein requirements for secretion of complete and genome-free hepatitis B virions

Ning, X., Luckenbaugh, L., Liu, K., Bruss, V., Sureau, C. & Hu, J., Jul 1 2018, In : Journal of virology. 92, 14, e00272-18.

Research output: Contribution to journalArticle

protein requirement
hepatitis B
surface proteins
Capsid Proteins
coat proteins
5 Citations (Scopus)

Hepatitis B virus core protein dephosphorylation occurs during pregenomic RNA encapsidation

Zhao, Q., Hu, Z., Cheng, J., Wu, S., Luo, Y., Chang, J., Hu, J. & Guo, J. T., Jul 1 2018, In : Journal of virology. 92, 13, e02139-17.

Research output: Contribution to journalArticle

Viral Core Proteins
Hepatitis B virus
dephosphorylation
RNA
Capsid

Magnetoresistance and Shubnikov-de Haas oscillations in layered Nb3SiTe6 thin flakes

An, L., Zhang, H., Hu, J., Zhu, X., Gao, W., Zhang, J., Xi, C., Ning, W., Mao, Z. & Tian, M., 2018, In : Physical Review B. 97, 23

Research output: Contribution to journalArticle

flakes
oscillations
electrical resistivity
Fermi surfaces
transport properties
3 Citations (Scopus)

Multiple roles of core protein linker in hepatitis B virus replication

Liu, K., Luckenbaugh, L., Ning, X., Xi, J. & Hu, J., May 1 2018, In : PLoS Pathogens. 14, 5, e1007085.

Research output: Contribution to journalArticle

Virus Replication
Hepatitis B virus
Virion
Capsid
Viral DNA

Multiple topologically nontrivial bands in noncentrosymmetric YSn2

Zhu, Y., Zhang, T., Hu, J., Kidd, J., Graf, D., Gui, X., Xie, W., Zhu, M., Ke, X., Cao, H., Fang, Z., Weng, H. & Mao, Z., 2018, In : Physical Review B. 98, 3

Research output: Contribution to journalArticle

metalloids
Brillouin zones
Fermi surfaces
platforms
fermions

Raman Spectroscopy, Photocatalytic Degradation, and Stabilization of Atomically Thin Chromium Tri-iodide

Shcherbakov, D., Stepanov, P., Weber, D., Wang, Y., Hu, J., Zhu, Y., Watanabe, K., Taniguchi, T., Mao, Z., Windl, W., Goldberger, J., Bockrath, M. & Lau, C. N., 2018, In : Nano letters. 18, 7, p. 4214-4219 6 p.

Research output: Contribution to journalArticle

Iodides
Chromium
iodides
Raman spectroscopy
chromium

Searching for topological Fermi arcs via quasiparticle interference on a type-II Weyl semimetal MoTe 2

Iaia, D., Chang, G., Chang, T-R., Hu, J., Mao, Z., Lin, H., Yan, S. & Madhavan, V., 2018, In : npj Quantum Materials. 3, 1

Research output: Contribution to journalArticle

Metalloids
metalloids
Fermi level
arcs
Scattering

Thickness evolution of transport properties in exfoliated Fe1+yTe nanoflakes

Hsieh, T-W., Zou, T., Hu, J., Mao, Z. Q., Zhang, P. P. & Ke, X., 2018, In : Journal of Physics Condensed Matter. 30, 29

Research output: Contribution to journalArticle

flakes
Magnetoresistance
Transport properties
transport properties
Phase transitions
2017
14 Citations (Scopus)

Capsid phosphorylation state and hepadnavirus virion secretion

Ning, X., Basagoudanavar, S. H., Liu, K., Luckenbaugh, L., Wei, D., Wang, C., Wei, B., Zhao, Y., Yan, T., Delaney, W. & Hu, J., May 1 2017, In : Journal of virology. 91, 9, e00092-17.

Research output: Contribution to journalArticle

Hepadnaviridae
capsid
Capsid
virion
Virion
41 Citations (Scopus)

Complete and incomplete hepatitis B virus particles: Formation, function, and application

Hu, J. & Liu, K., Mar 21 2017, In : Viruses. 9, 3, 56.

Research output: Contribution to journalReview article

Defective Viruses
Hepatitis B virus
Virion
Capsid
Genome
6 Citations (Scopus)

Identification of an intermediate in hepatitis B virus covalently closed circular (CCC) DNA formation and sensitive and selective CCC DNA detection

Luo, J., Cui, X., Gao, L. & Hu, J., Sep 1 2017, In : Journal of virology. 91, 17, e00539-17.

Research output: Contribution to journalArticle

circular DNA
Circular DNA
Hepatitis B virus
spleen exonuclease
DNA
1 Citation (Scopus)

In vitro assays for RNA binding and protein priming of hepatitis B virus polymerase

Clark, D. N., Jones, S. A. & Hu, J., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 157-177 21 p. (Methods in Molecular Biology; vol. 1540).

Research output: Chapter in Book/Report/Conference proceedingChapter

RNA-Binding Proteins
Hepatitis B virus
RNA
Viral DNA
Proteins
1 Citation (Scopus)

Mapping of functional subdomains in the terminal protein domain of hepatitis B virus polymerase

Clark, D. N., Flanagan, J. & Hu, J., Jan 1 2017, In : Journal of Virology. 91, 3, e01785-16.

Research output: Contribution to journalArticle

Hepatitis B virus
Proteins
proteins
RNA
Mutagenesis
2016
23 Citations (Scopus)

Cell-free hepatitis B virus capsid assembly dependent on the core protein C-terminal domain and regulated by phosphorylation

Ludgate, L., Liu, K., Luckenbaugh, L., Streck, N., Eng, S., Voitenleitner, C., Delaney, W. E. & Hu, J., Jun 1 2016, In : Journal of virology. 90, 12, p. 5830-5844 15 p.

Research output: Contribution to journalArticle

Virus Assembly
capsid
Hepatitis B virus
Capsid
Protein C
12 Citations (Scopus)

Minicircle HBV cccDNA with a Gaussia luciferase reporter for investigating HBV cccDNA biology and developing cccDNA-targeting drugs

Li, F., Cheng, L., Murphy, C. M., Reszka-Blanco, N. J., Wu, Y., Chi, L., Hu, J. & Su, L., Nov 7 2016, In : Scientific reports. 6, 36483.

Research output: Contribution to journalArticle

Circular DNA
Drug Delivery Systems
Luciferases
Hepatitis B virus
Chronic Hepatitis B
21 Citations (Scopus)

Viral DNA-dependent induction of innate immune response to hepatitis B virus in immortalized mouse hepatocytes

Cui, X., Clark, D. N., Liu, K., Xu, X. D., Guo, J. T. & Hu, J., Jan 1 2016, In : Journal of virology. 90, 1, p. 486-496 11 p.

Research output: Contribution to journalArticle

circular DNA
Circular DNA
Hepatitis B virus
Viral DNA
Innate Immunity
2015
17 Citations (Scopus)

Alteration of mature nucleocapsid and enhancement of covalently closed circular DNA formation by hepatitis B virus core mutants defective in complete-virion formation

Cui, X., Luckenbaugh, L., Bruss, V. & Hu, J., Jan 1 2015, In : Journal of virology. 89, 19, p. 10064-10072 9 p.

Research output: Contribution to journalArticle

circular DNA
Circular DNA
Nucleocapsid
nucleocapsid
Hepatitis B virus
28 Citations (Scopus)

Does tyrosyl DNA phosphodiesterase-2 play a role in hepatitis B virus genome repair?

Cui, X., McAllister, R., Boregowda, R., Sohn, J. A., Ledesma, F. C., Caldecott, K. W., Seeger, C. & Hu, J., Jun 16 2015, In : PloS one. 10, 6, e0128401.

Research output: Contribution to journalArticle

circular DNA
Circular DNA
Hepatitis B virus
Viruses
Repair
Virology
Antiviral Agents
Hepatitis B virus P protein
34 Citations (Scopus)

Genome-free hepatitis B virion levels in patient sera as a potential marker to monitor response to antiviral therapy

Luckenbaugh, L., Kitrinos, K. M., Delaney, W. E. & Hu, J., Jan 1 2015, In : Journal of Viral Hepatitis. 22, 6, p. 561-570 10 p.

Research output: Contribution to journalArticle

Hepatitis B
Virion
Antiviral Agents
Hepatitis B virus
Hepatitis B Surface Antigens
30 Citations (Scopus)

Hepadnavirus genome replication and persistence

Hu, J. & Seeger, C., Jan 1 2015, In : Cold Spring Harbor perspectives in medicine. 5, 7

Research output: Contribution to journalArticle

Hepadnaviridae
Circular DNA
Genes
Genome
Transcription
21 Citations (Scopus)

Hepatitis B virus covalently closed circular DNA formation in immortalized mouse hepatocytes associated with nucleocapsid destabilization

Cui, X., Guo, J. T. & Hu, J., Jan 1 2015, In : Journal of virology. 89, 17, p. 9021-9028 8 p.

Research output: Contribution to journalArticle

circular DNA
Circular DNA
Nucleocapsid
nucleocapsid
Hepatitis B virus
28 Citations (Scopus)

Hepatitis B virus reverse transcriptase - Target of current antiviral therapy and future drug development

Clark, D. N. & Hu, J., Nov 1 2015, In : Antiviral Research. 123, p. 132-137 6 p.

Research output: Contribution to journalReview article

RNA-Directed DNA Polymerase
Hepatitis B virus
Antiviral Agents
Drug Therapy
Viral DNA
19 Citations (Scopus)

Regulation of multiple stages of hepadnavirus replication by the carboxyl-terminal domain of viral core protein in trans

Liu, K., Ludgate, L., Yuan, Z. & Hu, J., Jan 1 2015, In : Journal of virology. 89, 5, p. 2918-2930 13 p.

Research output: Contribution to journalArticle

Hepadnaviridae
Duck Hepatitis B Viruses
Viral Core Proteins
Duck hepatitis B virus
circular DNA
6 Citations (Scopus)

Unveiling the roles of HBV polymerase for new antiviral strategies

Clark, D. N. & Hu, J., Mar 1 2015, In : Future Virology. 10, 3, p. 283-295 13 p.

Research output: Contribution to journalReview article

Antiviral Agents
RNA-Directed DNA Polymerase
RNA-Binding Proteins
DNA
RNA Stability
2014
16 Citations (Scopus)

Comparative analysis of hepatitis B virus polymerase sequences required for viral RNA binding, RNA packaging, and protein priming

Jones, S. A., Clark, D. N., Cao, F., Tavis, J. E. & Hu, J., Feb 1 2014, In : Journal of virology. 88, 3, p. 1564-1572 9 p.

Research output: Contribution to journalArticle

RNA-Binding Proteins
Hepatitis B virus
Viral RNA
Product Packaging
RNA
11 Citations (Scopus)

Sequences in the terminal protein and reverse transcriptase domains of the hepatitis B virus polymerase contribute to RNA binding and encapsidation

Cao, F., Jones, S., Li, W., Cheng, X., Hu, Y., Hu, J. & Tavis, J. E., Dec 1 2014, In : Journal of Viral Hepatitis. 21, 12, p. 882-893 12 p.

Research output: Contribution to journalArticle

RNA-Directed DNA Polymerase
Hepatitis B virus
RNA
Ducks
Proteins
2013
RNA-Directed DNA Polymerase
Anti-Infective Agents
Nucleosides
Hepatitis B virus
Drug Therapy

In Vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus Polymerase

Jones, S. A., Boregowda, R., Spratt, T. & Hu, J., Oct 29 2013, In : Journal of virology. 87, 22, 1 p.

Research output: Contribution to journalComment/debate

Hepatitis B virus
RNA
proteins
2 Citations (Scopus)

Maturation-associated destabilization of hepatitis b virus nucleocapsid

Cui, X., Ludgate, L., Ning, X. & Hu, J., Oct 25 2013, In : Journal of virology. 87, 21, p. 11493-11503 11 p.

Research output: Contribution to journalArticle

circular DNA
Circular DNA
Nucleocapsid
nucleocapsid
Hepatitis Viruses
33 Citations (Scopus)

Maturation-associated destabilization of hepatitis B virus nucleocapsid.

Cui, X., Ludgate, L., Ning, X. & Hu, J., Nov 1 2013, In : Journal of virology. 87, 21, p. 11494-11503 10 p.

Research output: Contribution to journalArticle

circular DNA
Circular DNA
Nucleocapsid
nucleocapsid
Hepatitis B virus
17 Citations (Scopus)

Noncompetitive inhibition of hepatitis B virus reverse transcriptase protein priming and DNA synthesis by the nucleoside analog clevudine

Jones, S. A., Murakami, E., Delaney, W., Furman, P. & Hu, J., Sep 1 2013, In : Antimicrobial Agents and Chemotherapy. 57, 9, p. 4181-4189 9 p.

Research output: Contribution to journalArticle

RNA-Directed DNA Polymerase
Nucleosides
Hepatitis B virus
Tenofovir
DNA
15 Citations (Scopus)

Protein-primed terminal transferase activity of hepatitis B virus polymerase

Jones, S. A. & Hu, J., Mar 1 2013, In : Journal of virology. 87, 5, p. 2563-2576 14 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Transferases
transferases
DNA
synthesis
2 Citations (Scopus)

Protein-Primed Terminal Transferase Activity of Hepatitis B Virus Polymerase

Jones, S. A. & Hu, J., Oct 29 2013, In : Journal of virology. 87, 22, 1 p.

Research output: Contribution to journalComment/debate

Hepatitis B virus
transferases
proteins
2012
29 Citations (Scopus)

Cyclin-dependent kinase 2 phosphorylates S/T-P sites in the hepadnavirus core protein C-terminal domain and is incorporated into viral capsids

Ludgate, L., Ning, X., Nguyen, D. H., Adams, C., Mentzer, L. & Hu, J., Nov 1 2012, In : Journal of Virology. 86, 22, p. 12237-12250 14 p.

Research output: Contribution to journalArticle

Hepadnaviridae
Cyclin-Dependent Kinase 2
capsid
Hepatitis B virus
cyclin-dependent kinase
38 Citations (Scopus)

In vitro epsilon RNA-dependent protein priming activity of human hepatitis B virus polymerase

Jones, S. A., Boregowd, R., Spratt, T. & Hu, J., May 1 2012, In : Journal of virology. 86, 9, p. 5134-5150 17 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Human Activities
RNA
Product Packaging
reverse transcription
6 Citations (Scopus)

TP-RT domain interactions of duck hepatitis B virus reverse transcriptase in cis and in trans during protein-primed initiation of DNA synthesis in vitro

Boregowda, R. K., Adams, C. & Hu, J., Jul 1 2012, In : Journal of Virology. 86, 12, p. 6522-6536 15 p.

Research output: Contribution to journalArticle

Duck hepatitis B virus
Duck Hepatitis B Viruses
RNA-directed DNA polymerase
RNA-Directed DNA Polymerase
synthesis
2011
16 Citations (Scopus)

A theoretical model for the dynamic structure of hepatitis B nucleocapsid

Meng, D., Hjelm, R. P., Hu, J. & Wu, J., Nov 16 2011, In : Biophysical Journal. 101, 10, p. 2476-2484 9 p.

Research output: Contribution to journalArticle

Nucleocapsid
Hepatitis B
Theoretical Models
Reverse Transcription
Hepatitis B virus
12 Citations (Scopus)

Cryptic protein priming sites in two different domains of duck hepatitis B virus reverse transcriptase for initiating DNA synthesis in vitro

Boregowda, R. K., Lin, L., Zhu, Q., Tian, F. & Hu, J., Aug 1 2011, In : Journal of Virology. 85, 15, p. 7754-7765 12 p.

Research output: Contribution to journalArticle

Duck hepatitis B virus
Duck Hepatitis B Viruses
RNA-directed DNA polymerase
RNA-Directed DNA Polymerase
synthesis
12 Citations (Scopus)

Phosphorylation State-Dependent interactions of hepadnavirus core protein with host factors

Ludgate, L., Adams, C. & Hu, J., Dec 22 2011, In : PLoS One. 6, 12, e29566.

Research output: Contribution to journalArticle

Hepadnaviridae
Integration Host Factors
Phosphorylation
phosphorylation
Duck hepatitis B virus
76 Citations (Scopus)

Secretion of genome-free hepatitis b virus - single strand blocking model for virion morphogenesis of para-retrovirus

Ning, X., Nguyen, D., Mentzer, L., Adams, C., Lee, H., Ashley, R., Hafenstein, S. & Hu, J., Sep 1 2011, In : PLoS Pathogens. 7, 9, e1002255.

Research output: Contribution to journalArticle

Hepatitis Viruses
Retroviridae
Morphogenesis
Virion
Genome
2009
17 Citations (Scopus)

An interdomain RNA binding site on the hepadnaviral polymerase that is essential for reverse transcription

Badtke, M. P., Khan, I., Cao, F., Hu, J. & Tavis, J. E., Jul 20 2009, In : Virology. 390, 1, p. 130-138 9 p.

Research output: Contribution to journalArticle

Viral RNA
Reverse Transcription
Binding Sites
RNA
DNA