Projects per year
Personal profile
Teaching and educational interests
Dr. John Elfar's laboratory is part of the Center for Orthopaedic Research and Translational Science. His group accepts postdoctoral and graduate-level trainees as well as resident physicians seeking a greater involvement in translational research. Dr. Elfar has mentored more than 60 such trainees who have completed clinical subspecialty training both inside and outside of orthopedic surgery.
Clinical interests
Dr. John Elfar specializes in sports, hand and upper extremity surgery, in addition to orthopedic reconstructive surgery. These areas are among Dr. Elfar's clinical interests: nerve compression (pinched nerve), shoulder arthroscopy and elbow arthroscopy, arthroplasty (joint replacement procedures) and complex reconstruction. He is affiliated with Penn State Health Milton S. Hershey Medical Center.
Research interests
Dr. John Elfar is a surgeon-scientist at Penn State College of Medicine. In addition to being a practicing orthopedic surgeon, he directs the Center for Orthopaedic Research and Translational Science (CORTS). This group includes multiple laboratories dedicated to translational orthopaedic research in all its forms. There is a focus on orthopaedic population studies, basic science, cell and RNA biology, epidemiology, biomechanics and drug repurposing for the treatment of musculoskeletal complaints.
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Projects
- 1 Finished
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Erythropoietin for Neuroregeneration
Elfar, J. & Elfar, J.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
1/1/13 → 8/31/18
Project: Research project
Research Output
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Aberrant structure of fibrillar collagen and elevated levels of advanced glycation end products typify delayed fracture healing in the diet-induced obesity mouse model
Khajuria, D. K., Soliman, M., Elfar, J. C., Lewis, G. S., Abraham, T., Kamal, F. & Elbarbary, R. A., Aug 2020, In: Bone. 137, 115436.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
An effective erythropoietin dose regimen protects against severe nerve injury-induced pathophysiological changes with improved neural gene expression and enhances functional recovery
Govindappa, P. K., Talukder, M. A. H., Gurjar, A. A., Hegarty, J. P. & Elfar, J. C., May 2020, In: International Immunopharmacology. 82, 106330.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Human equivalent dose of oral 4-aminopyridine differentiates nerve crush injury from transection injury and improves post-injury function in mice
Hsu, C., Talukder, M., Yue, L., Turpin, L., Noble, M. & Elfar, J., Nov 1 2020, In: Neural Regeneration Research. 15, 11, p. 2098-2107 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Novel FEMASK-score, a histopathologic assessment for destructive Charcot neuropathic arthropathy, reveals intraneural vasculopathy and correlates with progression and best treatment
King, J., Murie, B., Fanburg-Smith, J. C., Stauch, C. M., Flemming, D., Klein, M. J., Frauenhoffer, E. E., Fritsche, M., Smith, J. D., Elfar, J. & Aynardi, M., Aug 2020, In: Annals of Diagnostic Pathology. 47, 151509.Research output: Contribution to journal › Article › peer-review
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Peripheral nerve injury and myelination: Potential therapeutic strategies
Modrak, M., Talukder, M. A. H., Gurgenashvili, K., Noble, M. & Elfar, J. C., May 1 2020, In: Journal of Neuroscience Research. 98, 5, p. 780-795 16 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations