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John Elfar, MD

 https://orcid.org/0000-0002-4438-7118
    • 847 Citations
    • 15 h-Index
    20012020

    Research output per year

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    Personal profile

    Teaching and educational interests

    Dr. John Elfar's laboratory is part of the Center for Orthopaedic Research and Translational Science. His group accepts postdoctoral and graduate-level trainees as well as resident physicians seeking a greater involvement in translational research. Dr. Elfar has mentored more than 60 such trainees who have completed clinical subspecialty training both inside and outside of orthopedic surgery.

    Clinical interests

    Dr. John Elfar specializes in sports, hand and upper extremity surgery, in addition to orthopedic reconstructive surgery. These areas are among Dr. Elfar's clinical interests: nerve compression (pinched nerve), shoulder arthroscopy and elbow arthroscopy, arthroplasty (joint replacement procedures) and complex reconstruction. He is affiliated with Penn State Health Milton S. Hershey Medical Center.

    Research interests

    Dr. John Elfar is a surgeon-scientist at Penn State College of Medicine. In addition to being a practicing orthopedic surgeon, he directs the Center for Orthopaedic Research and Translational Science (CORTS). This group includes multiple laboratories dedicated to translational orthopaedic research in all its forms. There is a focus on orthopaedic population studies, basic science, cell and RNA biology, epidemiology, biomechanics and drug repurposing for the treatment of musculoskeletal complaints.

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    Projects

    Erythropoietin for Neuroregeneration

    Elfar, J.

    National Institutes of Health

    1/1/13 → 12/31/17

    Project: Research project

    • Research Output

    An effective erythropoietin dose regimen protects against severe nerve injury-induced pathophysiological changes with improved neural gene expression and enhances functional recovery

    Govindappa, P. K., Talukder, M. A. H., Gurjar, A. A., Hegarty, J. P. & Elfar, J. C., May 2020, In : International Immunopharmacology. 82, 106330.

    Research output: Contribution to journal › Article

    • Peripheral nerve injury and myelination: Potential therapeutic strategies

    Modrak, M., Talukder, M. A. H., Gurgenashvili, K., Noble, M. & Elfar, J. C., May 1 2020, In : Journal of Neuroscience Research. 98, 5, p. 780-795 16 p.

    Research output: Contribution to journal › Review article

    • 1 Scopus citations

    Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice

    Clark, A., Hsu, C., Hassan Talukder, M., Noble, M. & Elfar, J., Jan 1 2020, In : Neural Regeneration Research. 15, 1, p. 136-144 9 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Zoledronic Acid Improves Muscle Function in Healthy Mice Treated with Chemotherapy

    Hain, B. A., Jude, B., Xu, H., Smuin, D. M., Fox, E. J., Elfar, J. C. & Waning, D. L., Feb 1 2020, In : Journal of Bone and Mineral Research. 35, 2, p. 368-381 14 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    4-Aminopyridine as a single agent diagnostic and treatment for severe nerve crush injury

    Noble, M., Tseng, K. C., Li, H. & Elfar, J. C., Mar 1 2019, In : Military medicine. 184, p. 379-385 7 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations