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John Ellis, PhD

    • 1560 Citations
    • 23 h-Index
    1980 …2019
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    • 2 Similar Profiles
    Muscarinic Receptors Medicine & Life Sciences
    Gallamine Triethiodide Medicine & Life Sciences
    Allosteric Site Medicine & Life Sciences
    N-Methylscopolamine Medicine & Life Sciences
    Ligands Medicine & Life Sciences
    Cholinergic Agents Medicine & Life Sciences
    Epitopes Medicine & Life Sciences
    Muscarinic M2 Receptors Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Projects 1984 2019

    RESPONSES OF SUBPOPULATIONS OF MUSCARINIC RECEPTORS

    Ellis, J.

    National Institutes of Health

    2/1/85 → 8/31/19

    Project: Research project

    Muscarinic Receptors
    Cholinergic Agents
    Allosteric Site
    Ligands
    Pharmacology

    PLATELET ALPHA 2 RECEPTORS--MODELS FOR EFFECTOR COUPLING

    Ellis, J.

    National Institutes of Health

    4/1/84 → 9/30/87

    Project: Research project

    Blood Platelets
    Adenylyl Cyclases
    Adrenergic Receptors
    Nucleotides
    Biomarkers

    Research Output 1980 2017

    • 1560 Citations
    • 23 h-Index
    • 45 Article
    • 1 Short survey
    • 1 Review article

    Dronedarone Modulates M1 and M3 Muscarinic Receptors with Subtype Selectivity, Functional Selectivity, and Probe Dependence

    Jayasuriya, G. M., Elmslie, G., Burstein, E. S. & Ellis, J., Mar 1 2017, In : Pharmacology. 99, 3-4, p. 128-138 11 p.

    Research output: Contribution to journal › Article

    Muscarinic M3 Receptors
    Muscarinic M1 Receptors
    Amiodarone
    Allosteric Site
    Acetylcholine
    18 Citations (Scopus)

    Allosteric modulation in monomers and oligomers of a G protein-coupled receptor

    Shivnaraine, R. V., Kelly, B., Sankar, K. S., Redka, D. S., Han, Y. R., Huang, F., Elmslie, G., Pinto, D., Li, Y., Rocheleau, J. V., Gradinaru, C. C., Ellis, J. & Wells, J. W., May 6 2016, In : eLife. 5, MAY2016, e11685.

    Research output: Contribution to journal › Article

    Muscarinic M2 Receptors
    G-Protein-Coupled Receptors
    Static Electricity
    Oligomers
    Monomers
    21 Citations (Scopus)

    Coupling of G proteins to reconstituted monomers and tetramers of the M 2 muscarinic receptor

    Redka, D. S., Morizumi, T., Elmslie, G., Paranthaman, P., Shivnaraine, R. V., Ellis, J., Ernst, O. P. & Wells, J. W., Jan 1 2014, In : Journal of Biological Chemistry. 289, 35, p. 24347-24365 19 p.

    Research output: Contribution to journal › Article

    Guanylyl Imidodiphosphate
    Muscarinic Receptors
    GTP-Binding Proteins
    Monomers
    G-Protein-Coupled Receptors
    7 Citations (Scopus)

    Heterotropic cooperativity within and between protomers of an oligomeric M 2 muscarinic receptor

    Shivnaraine, R. V., Huang, X. P., Seidenberg, M., Ellis, J. & Wells, J. W., Jun 5 2012, In : Biochemistry. 51, 22, p. 4518-4540 23 p.

    Research output: Contribution to journal › Article

    Gallamine Triethiodide
    Protein Subunits
    Muscarinic Receptors
    Allosteric Site
    Sf9 Cells
    6 Citations (Scopus)

    Allosteric modulation of the M3 muscarinic receptor by amiodarone and N-ethylamiodarone: Application of the four-ligand allosteric two-state model

    Stahl, E., Elmslie, G. & Ellis, J., Sep 1 2011, In : Molecular Pharmacology. 80, 3, p. 378-388 11 p.

    Research output: Contribution to journal › Article

    Muscarinic M3 Receptors
    Amiodarone
    Allosteric Site
    Ligands
    Acetylcholine