• 1576 Citations
  • 23 h-Index
1980 …2020

Research output per year

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Research Output

  • 1576 Citations
  • 23 h-Index
  • 45 Article
  • 1 Short survey
  • 1 Review article
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Article
2017

Dronedarone Modulates M1 and M3 Muscarinic Receptors with Subtype Selectivity, Functional Selectivity, and Probe Dependence

Jayasuriya, G. M., Elmslie, G., Burstein, E. S. & Ellis, J., Mar 1 2017, In : Pharmacology. 99, 3-4, p. 128-138 11 p.

Research output: Contribution to journalArticle

2016

Allosteric modulation in monomers and oligomers of a G protein-coupled receptor

Shivnaraine, R. V., Kelly, B., Sankar, K. S., Redka, D. S., Han, Y. R., Huang, F., Elmslie, G., Pinto, D., Li, Y., Rocheleau, J. V., Gradinaru, C. C., Ellis, J. & Wells, J. W., May 6 2016, In : eLife. 5, MAY2016, e11685.

Research output: Contribution to journalArticle

18 Scopus citations
2014

Coupling of G proteins to reconstituted monomers and tetramers of the M2 muscarinic receptor

Redka, D. S., Morizumi, T., Elmslie, G., Paranthaman, P., Shivnaraine, R. V., Ellis, J., Ernst, O. P. & Wells, J. W., Jan 1 2014, In : Journal of Biological Chemistry. 289, 35, p. 24347-24365 19 p.

Research output: Contribution to journalArticle

23 Scopus citations
2012

Heterotropic cooperativity within and between protomers of an oligomeric M2 muscarinic receptor

Shivnaraine, R. V., Huang, X. P., Seidenberg, M., Ellis, J. & Wells, J. W., Jun 5 2012, In : Biochemistry. 51, 22, p. 4518-4540 23 p.

Research output: Contribution to journalArticle

7 Scopus citations
2011

Allosteric modulation of the M3 muscarinic receptor by amiodarone and N-ethylamiodarone: Application of the four-ligand allosteric two-state model

Stahl, E., Elmslie, G. & Ellis, J., Sep 1 2011, In : Molecular pharmacology. 80, 3, p. 378-388 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2010

Novel allosteric effects of amiodarone at the muscarinic M5 receptor

Stahl, E. & Ellis, J., Jul 1 2010, In : Journal of Pharmacology and Experimental Therapeutics. 334, 1, p. 214-222 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
2007
12 Scopus citations
2006
52 Scopus citations
2005

Atypical muscarinic allosteric modulation: Cooperativity between modulators and their atypical binding topology in muscarinic M2 and M 2/M5 chimeric receptors

Tränkle, C., Dittmann, A., Schulz, U., Weyand, O., Buller, S., Jöhren, K., Heller, E., Birdsall, N. J. M., Holzgrabe, U., Ellis, J., Höltje, H. D. & Mohr, K., Dec 1 2005, In : Molecular pharmacology. 68, 6, p. 1597-1610 14 p.

Research output: Contribution to journalArticle

45 Scopus citations
50 Scopus citations
2003

Allosteric site on muscarinic acetylcholine receptors: Identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors

Voigtländer, U., Jöhren, K., Mohr, M., Raasch, A., Tränkle, C., Buller, S., Ellis, J., Höltje, H. D. & Mohr, K., Jul 1 2003, In : Molecular pharmacology. 64, 1, p. 21-31 11 p.

Research output: Contribution to journalArticle

85 Scopus citations
2002
55 Scopus citations
25 Scopus citations
2000
12 Scopus citations
1999
12 Scopus citations
86 Scopus citations
1996

Allosteric regulation of the binding of [3H]acetylcholine to m2 muscarinic receptors

Gnagey, A. & Ellis, J., Dec 13 1996, In : Biochemical Pharmacology. 52, 11, p. 1767-1775 9 p.

Research output: Contribution to journalArticle

26 Scopus citations
1993

Muscarinic acetylcholine receptor subtypes: Localization and structure/function

Brann, M. R., Ellis, J., Jørgensen, H., Hill-Eubanks, D. & Jones, S. V. P., Jan 1 1993, In : Progress in Brain Research. 98, C, p. 121-127 7 p.

Research output: Contribution to journalArticle

91 Scopus citations

Structure/function relationships of muscarinic acetylcholine receptors

Brann, M. R., Klimkowski, V. J. & Ellis, J., 1993, In : Life Sciences. 52, 5-6, p. 405-412 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Studies of the Pharmacology, Localization, and Structure of Muscarinic Acetylcholine Receptors

BRANN, MARK. R., JØRGENSEN, HANS. B., BURSTEIN, ETHAN. S., SPALDING, TRACY. A., ELLIS, JOHN., JONES, S. V. PENELOPE. & HILL‐EUBANKS, DAVID., Dec 1993, In : Annals of the New York Academy of Sciences. 707, 1, p. 225-236 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Use of chimeric muscarinic receptors to investigate epitopes involved in allosteric interactions

Ellis, J., Seidenberg, M. & Brann, M. R., 1993, In : Molecular Pharmacology. 44, 3, p. 583-588 6 p.

Research output: Contribution to journalArticle

54 Scopus citations
1992

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

Lenox, R. H., Watson, D. G., Patel, J. & Ellis, J., Jan 20 1992, In : Brain research. 570, 1-2, p. 333-340 8 p.

Research output: Contribution to journalArticle

125 Scopus citations

Two allosteric modulators interact at a common site on cardiac muscarinic receptors

Ellis, J. & Seidenberg, M., 1992, In : Molecular Pharmacology. 42, 4, p. 638-641 4 p.

Research output: Contribution to journalArticle

87 Scopus citations
1991

Allosteric regulation of cloned m1-m5 muscarinic receptor subtypes

Ellis, J., Huyler, J. & Brann, M. R., Oct 24 1991, In : Biochemical Pharmacology. 42, 10, p. 1927-1932 6 p.

Research output: Contribution to journalArticle

101 Scopus citations

Muscarinic receptor regulation and protein kinase C: Sites for the action of chronic lithium in the hippocampus

Lenox, R. H., Watson, D. G. & Ellis, J., 1991, In : Psychopharmacology Bulletin. 27, 3, p. 191-197 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Receptor coupling to G proteins: Interactions not affected by lithium

Ellis, J. & Lenox, R. H., 1991, In : Lithium. 2, 3, p. 141-147 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
1990

Chronic lithium treatment prevents atropine-induced supersensitivity of the muscarinic phosphoinositide response in rat hippocampus

Ellis, J. & Lenox, R. H., Oct 1 1990, In : Biological Psychiatry. 28, 7, p. 609-619 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Muscarinic receptors and second-messenger responses of neurons in primary culture

Ellis, J., Huyler, J. H., Kemp, D. E. & Weiss, S., Mar 19 1990, In : Brain research. 511, 2, p. 234-240 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
1989

Gallamine exerts biphasic allosteric effects at muscarinic receptors

Ellis, J. & Seidenberg, M., Jan 1 1989, In : Molecular pharmacology. 35, 2, p. 173-176 4 p.

Research output: Contribution to journalArticle

26 Scopus citations
74 Scopus citations
1988

Desensitization of Muscarinic Receptor‐Coupled Phosphoinositide Hydrolysis in Rat Hippocampus: Comparisons with the α1‐Adrenergic Response

Lenox, R. H., Hendley, D. & Ellis, J., Jan 1 1988, In : Journal of neurochemistry. 50, 2, p. 558-564 7 p.

Research output: Contribution to journalArticle

39 Scopus citations
5 Scopus citations
1987

Interactions between gallamine and muscarinic receptors: allosterism and subpopulation specificity are separate phenomena

Ellis, J. & Seidenberg, M., Nov 24 1987, In : European Journal of Pharmacology. 144, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Receptor‐Coupled Hydrolysis of Phosphoinositides in Rat Hippocampal Slices: Muscarinic Versus Adrenergic

LENOX, ROBERT. H., HENDLEY, DANIEL. D. & Ellis, J., Jan 1 1987, In : Annals of the New York Academy of Sciences. 494, 1, p. 129-131 3 p.

Research output: Contribution to journalArticle

α2-Adrenergic receptors mediate inhibition of cyclic AMP production in neurons in primary culture

Weiss, S., Kemp, D. E., Lenox, R. H. & Ellis, J., Jun 30 1987, In : Brain research. 414, 2, p. 390-394 5 p.

Research output: Contribution to journalArticle

14 Scopus citations
1985

Alpha2-adrenergic receptor-mediated regulation of adenylate cyclase in the intact human platelet. Evidence for a receptor reserve

Lenox, R. H., Ellis, J., Van Riper, D. & Ehrlich, Y. H., 1985, In : Molecular Pharmacology. 27, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Characterization of the interactions of gallamine with muscarinic receptors from brain

Ellis, J. & Lenox, R. H., Jun 15 1985, In : Biochemical Pharmacology. 34, 12, p. 2214-2217 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Muscarinic Receptor Subtypes in the Central Nervous System

Hoss, W. & Ellis, J., Jan 1 1985, In : International Review of Neurobiology. 26, C, p. 151-199 49 p.

Research output: Contribution to journalArticle

26 Scopus citations
13 Scopus citations
1984

Cross-species septal transplants: recovery of choline acetyltransferase activity

Daniloff, J. K., Wells, J. & Ellis, J., Dec 17 1984, In : Brain research. 324, 1, p. 151-154 4 p.

Research output: Contribution to journalArticle

26 Scopus citations
1983

Automated analysis of stereotypic behavior induced by psychomotor stimulants

Brann, M. R., Hacker, M., Finnerty, M., Ellis, J., Lenox, R. H. & Ehrlich, Y. H., Jan 1 1983, In : Pharmacology, Biochemistry and Behavior. 19, 1, p. 57-62 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
1982

Competitive interaction of gallamine with multiple muscarinic receptors

Ellis, J. & Hoss, W., Mar 1 1982, In : Biochemical Pharmacology. 31, 5, p. 873-876 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

GTP-preferring protein phosphorylation systems in brain membranes: Possible role in adenylate cyclase regulation

Ehrlich, Y. H., Whittemore, S. R., Lambert, R., Ellis, J., Graber, S. G. & Lenox, R. H., Jul 30 1982, In : Biochemical and Biophysical Research Communications. 107, 2, p. 699-706 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Turning induced by unilateral injection of antimicrotubular agents into the substantia nigra

Brann, M. R., Finnerty, M., Ellis, J., Lenox, R. H. & Ehrlich, Y. H., 1982, In : Progress in Neuropsychopharmacology and Biological Psychiatry. 6, 4-6, p. 347-350 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
1980

Analysis of regional variations in the affinities of muscarinic agonists in the rat brain

Ellis, J. & Hoss, W., Jul 7 1980, In : Brain research. 193, 1, p. 189-198 10 p.

Research output: Contribution to journalArticle

30 Scopus citations