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Personal profile

Research interests

Dr. John Richie's research focuses on understanding factors that regulate cancer risk in individuals and in populations.

Using an interdisciplinary research approach, the aim is to identify the roles and mechanisms of key factors, alone and in combination, that impact cancer risk, with the ultimate goal of utilizing this information in the design and development of targeted prevention strategies.

The major areas of focus include aging, nutrition, tobacco and race/ethnicity as regulators or determinants of cancer risk. In particular, Dr. Richie looks at factors related to the generation of and protection against oxidative damage.

In an ongoing molecular epidemiology study of tobacco-related cancers in black and white Americans, Dr. Richie's work investigates metabolic and genetic factors that may be responsible, in part, for observed racial differences in tobacco-related cancer rates.

In other studies, Dr. Richie's team is examining the role of glutathione, the major endogenous antioxidant in nearly all cells and tissues, in protecting against oxidative damage during aging, and its relationship with cancer development.

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Projects

  • INTERDISCIPLINARY STUDIES IN CANCER EPIDEMIOLOGY

    Richie, J., Zang, E., Djordjevic, M., Koo, L., Stellman, S. & Lazarus, P.

    National Institutes of Health

    9/8/958/31/08

    Project: Research project

  • BPH GROWTH REGULATION MODEL

    Richie, J. & Richie, J.

    National Institutes of Health

    9/30/929/29/98

    Project: Research project

  • Research Output

    An Electronic Aerosol Delivery System for Functional Magnetic Resonance Imaging

    Hobkirk, A. L., Bitzer, Z., Goel, R., Sica, C. T., Livelsberger, C., Yingst, J., Houser, K. R., Rupprecht, S., Trushin, N., Karunanayaka, P., Foulds, J., Richie, J. P., Spreen, L., Hoglen, B., Wang, J., Elias, R. J. & Yang, Q. X., Jan 1 2020, In : Substance Abuse: Research and Treatment. 14

    Research output: Contribution to journalArticle

    Open Access
  • Are Ergothioneine Levels in Blood Associated with Chronic Peripheral Neuropathy in Colorectal Cancer Patients Who Underwent Chemotherapy?

    Winkels, R. M., van Brakel, L., van Baar, H., Beelman, R. B., van Duijnhoven, F. J. B., Geijsen, A., van Halteren, H. K., Hansson, B. M. E., Richie, J. P., Sun, D., Wesselink, E., van Zutphen, M., Kampman, E. & Kok, D. E., Apr 2 2020, In : Nutrition and cancer. 72, 3, p. 451-459 9 p.

    Research output: Contribution to journalArticle

    Open Access
  • Open Access
  • Methionine restriction delays aging-related urogenital diseases in male Fischer 344 rats

    Komninou, D., Malloy, V. L., Zimmerman, J. A., Sinha, R. & Richie, J. P., Feb 1 2020, In : GeroScience. 42, 1, p. 287-297 11 p.

    Research output: Contribution to journalArticle

  • Pharmacokinetic Profile of Spectrum Reduced Nicotine Cigarettes

    Kamens, H. M., Silva, C. P., Nye, R. T., Miller, C. N., Singh, N., Sipko, J., Trushin, N., Sun, D., Branstetter, S. A., Muscat, J. E., Richie, J. P. & Foulds, J., Feb 6 2020, In : Nicotine and Tobacco Research. 22, 2, p. 273-279 7 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Prizes

    Outstanding Collaborative Research Award

    Karam El-Bayoumy (Recipient), Andrea Manni (Recipient), John Richie (Recipient), Jiangang (Jason) Liao (Recipient), John Patrick Vanden Heuvel (Recipient), Laurence Demers (Recipient), James Dillard (Recipient) & Connie Jo Rogers (Recipient), 2016

    Prize