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Research interests

Jonathan G. Stine, MD, MSc, FACP, is an Assistant Professor of Medicine and funded physician scientist in the Division of Gastroenterology and Hepatology at Penn State Health Milton S. Hershey Medical Center. Dr. Stine earned his undergraduate degree from Penn State.

Dr. Stine's clinical and research areas of expertise include NAFLD, coagulation disorders in chronic liver disease, drug-induced liver injury (DILI) and liver transplantation. The majority of his early work focused on DILI in both the population at large, as well as in special populations, including the elderly and patients with underlying chronic liver disease including cirrhosis. His more recent work has focused on liver transplantation coagulation disorders and outcomes-based research in which the link between pre- and post-transplantation vascular events was demonstrated. Additionally, Dr. Stine and his research group found that despite broader organ-sharing policies, geographic disparities persist and regional access to liver transplantation remains highly variable and inequitable.

Dr. Stine is the principal investigator on the NASHFit Trial and is continuing forward his work on the hypercoagulable environment in NASH patients, where he previously demonstrated that NASH increases one's risk of venous thromboembolic disease.

Dr. Stine serves as the Director of Research, Penn State Liver Center.

Professional information

Fellow of the American College of Physicians (FACP), 2016

Education/Academic qualification

Transplant Hepatology Fellowship, NIH/NIDDK T32 training grant, University of Virginia

… → 2017

Gastroenterology and Hepatology Fellowship, NIH/NIDDK T32 training grant, University of Virginia

… → 2016

Masters of Science in Clinical Research, University of Virginia

… → 2015

Internal Medicine, Chief Medical Residency, Georgetown University Hospital

… → 2013

Internal Medicine Residency, Georgetown University Hospital

… → 2012

MD, Georgetown University

… → 2009

Nutritional Sciences, BS, The Pennsylvania State University

… → 2005

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Thrombosis Medicine & Life Sciences
Portal Vein Medicine & Life Sciences
Chemical and Drug Induced Liver Injury Medicine & Life Sciences
Fibrosis Medicine & Life Sciences
Liver Medicine & Life Sciences
Liver Transplantation Medicine & Life Sciences
Transplants Medicine & Life Sciences
Liver Diseases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2018 2020

Research Output 2007 2020

Liver transplant candidates have impaired quality of life across health domains as assessed by computerized testing

Stine, J. G., Stukenborg, G. J., Wang, J., Adkins, A., Niccum, B., Zimmet, A. & Argo, C. K., Jan 1 2020, In : Annals of Hepatology. 19, 1, p. 62-68 7 p.

Research output: Contribution to journalArticle

Open Access
Quality of Life
Liver Transplantation

Clinical Cirrhosis Dilemmas: Survey of Practice from the 7th International Coagulation in Liver Disease Conference

Stine, J. G., Intagliata, N. M., Shah, N. L., Lisman, T., Violi, F., Caldwell, S. H. & Argo, C. K., Jan 1 2019, (Accepted/In press) In : Digestive Diseases and Sciences.

Research output: Contribution to journalArticle

Liver Diseases
Mesenteric Veins
Chronic Disease
1 Citation (Scopus)

Development of a Model to Predict Portal Vein Thrombosis in Liver Transplant Candidates: The Portal Vein Thrombosis Risk Index

Gaballa, D., Bezinover, D., Kadry, Z., Eyster, E., Wang, M., Northup, P. G. & Stine, J. G., Dec 1 2019, In : Liver Transplantation. 25, 12, p. 1747-1755 9 p.

Research output: Contribution to journalArticle

Portal Vein
End Stage Liver Disease

Hyponatremia Is Protective Against the Development of Portal Vein Thrombosis in Patients Undergoing Liver Transplant

Bezinover, D., Navabi, S., Wang, M., Li, Z., William, M. & Stine, J. G., Jul 1 2019, In : Transplantation proceedings. 51, 6, p. 1880-1886 7 p.

Research output: Contribution to journalArticle

Portal Vein